There is a war outside the wire and we fight it every day on patrol, but the enemy is among us. There is another war, inside the wire, that although fought in silence is no less important to your safety. In some ways it is even more important because a man with his guard down is more vulnerable than a soldier prepared to meet his enemy in battle." As a Senior Counterintelligence Agent in Iraq, this is what Dr. Richard Saccone warned during staff meetings with combat troops facing bullets every day. Today's modern leaner military requires the hiring of thousands of contract workers and local nationals to work on U.S. bases performing services from translation to manual labor, light construction, maintenance and more. Out of the several thousand non-military personnel hired, insurgents are unceasing in their attempts to infiltrate, living and working right next to U.S. soldiers every day. Access and information are highly valuable commodities. Whether they are insurgents, sympathizers or working under threat of harm to themselves or their loved ones, it is difficult to know where true loyalties lie. Sifting through this human haystack, searching for the proverbial insurgent needle is the job of Counterintelligence (CI). Skilled CI agents work closely with Force Protection soldiers to identify and eliminate infiltrators and spies before they can harm U.S. forces in the sanctuary of their homes. This is the unseen war; the war not captured by the media. Without revealing classified methods that would undermine the CI effort, Dr. Saccone exposes the reader to the Unseen War in Iraq, a war of cloak-and-dagger and intrigue, a war interesting in its methods and critical to overall success. He reflects on his time spent at Abu Ghraib prison, raises thought-provoking questions relating to the difference between torture and coercive techniques, methods to distinguish between the "good guys" and the "bad guys" and provides deep insight into ways the military could improve their counterintelligence strategy.
In the midst of an addiction epidemic, this newly updated edition of The American Society of Addiction Medicine Principles of Addiction Medicine, 5th edition is the sought-after text every addiction researcher and care provider needs. This comprehensive reference text dedicates itself to both the science and treatment of addiction. You’ll receive a thorough grounding in both the scientific principles behind the causes of addiction and the practical aspects of clinical care. Chapters are written by recognized experts, covering areas such as the basic science of addiction medicine; diagnosis, assessment and early intervention; pharmacologic and behavioral interventions; mutual help and twelve-step; and co-occurring addiction, medical and psychiatric disorders—backed by the latest research data and successful treatment methods. Features: Numerous figures, tables and diagrams elucidate the text Chapters include case examples List of data research reports provided at end of each chapter NEW material on Prescription Drug Abuse, Club Drugs, Nursing Roles in Addressing Addiction, Conceptual and Treatment Issues in Behavioral Addictions, Rehabilitation Approaches to Pain Management, Comorbid Pain and Addiction, Pharmacotherapy for Adolescents with Substance Use Disorders, Preventing and Treating Substance Use Disorders in Military Personnel, and more.
Principles of Addiction Medicine, 7th ed is a fully reimagined resource, integrating the latest advancements and research in addiction treatment. Prepared for physicians in internal medicine, psychiatry, and nearly every medical specialty, the 7th edition is the most comprehensive publication in addiction medicine. It offers detailed information to help physicians navigate addiction treatment for all patients, not just those seeking treatment for SUDs. Published by the American Society of Addiction Medicine and edited by Shannon C. Miller, MD, Richard N. Rosenthal, MD, Sharon Levy, MD, Andrew J. Saxon, MD, Jeanette M. Tetrault, MD, and Sarah E. Wakeman, MD, this edition is a testament to the collective experience and wisdom of 350 medical, research, and public health experts in the field. The exhaustive content, now in vibrant full color, bridges science and medicine and offers new insights and advancements for evidence-based treatment of SUDs. This foundational textbook for medical students, residents, and addiction medicine/addiction psychiatry fellows, medical libraires and institution, also serves as a comprehensive reference for everyday clinical practice and policymaking. Physicians, mental health practitioners, NP, PAs, or public officials who need reference material to recognize and treat substance use disorders will find this an invaluable addition to their professional libraries.
Carcinoma of the lung is one of the most prevalent and aggressive types of cancer, and rates of lung cancer are on the rise. This issue gives a comprehensive review of the most recent advances in Lung Cancer. Epidemiology, etiology, and prevention of lung cancer is first discussed, followed by articles on pre-invasive evaluation and management, screening, pathology and molecular biology. There is an article on the approach to the ground glass nodule. Of great importance is the revised staging classification of Lung Cancer, which is discussed here in detail. Articles on PET imaging, interventional pulmonary, and functional evaluation before Lung Resection are also included. The issue then focuses on advances in treatment for early stage lung cancer, high risk patients with early stage lung cancer, advances in the treatment of Advanced Stage Lung Cancer, Small Cell Lung Cancer, and gene therapy for lung neoplasms.
This book provides a comprehensive exploration of hypersonic technology, focusing on its growing significance in modern warfare. It is structured into five parts, each addressing a different aspect of hypersonic weapons. Part I lays the foundation, explaining the definition, types, and characteristics of hypersonic weapons, such as glide vehicles and cruise missiles. It covers the physics of hypersonic flight, the challenges posed by extreme speeds, and the materials needed to withstand such conditions. A detailed analysis of propulsion systems like scramjets and ramjets highlights future innovations in this field. In Part II, the book delves into the development and testing of hypersonic weapons. It explores their evolution, from Cold War-era experiments to modern programs led by the U.S., Russia, and China. Testing facilities and challenges associated with high-speed flight, such as wind tunnels and simulation tools, are discussed in depth. Part III addresses the military and strategic implications of hypersonic weapons. It emphasizes their offensive capabilities, the difficulty of defending against them, and their role in global power dynamics. The global arms race is examined, with a focus on how hypersonic weapons fit into national defence strategies, and the delicate balance between conventional and nuclear systems is considered. Part IV outlines the technical challenges and countermeasures to hypersonic weapons, including detection and interception difficulties. International collaboration on missile defence and the ethical and legal concerns surrounding these weapons are also explored. Finally, Part V looks to the future, discussing emerging technologies, the potential for space-based hypersonic platforms, and the changing nature of warfare in a hypersonic age. The book concludes with insights into the future challenges and opportunities presented by hypersonic weapons in global security.
In the early part of the twentieth century, Argentina's Socialist Party became the largest and most effective socialist organization in Latin America. Richard J. Walter's interpretive study begins with the party's origins in the 1890s, traces its development through 1912, and then offers a comprehensive analysis of its activities and programs during the almost two decades of civilian, democratic government that ended with the military coup of 1930. His aim has been to provide a detailed case study of a Latin American political party within a specific historical context. The work gives particular attention to the nature of party leadership, internal party organization, attempts to win the support of the Argentine working class, party activities in national elections and the National Congress, and internal disputes and divisions. In discussing these topics, Walter draws heavily on government documents, including national and municipal censuses, ministerial reports, and the Argentine Congressional Record. He also makes extensive use of national and party newspapers and journals, political memoirs, and collections of essays by party leaders. Walter concludes that the party enjoyed relative electoral and legislative success because of efficient organization, capable leadership, and specific, well-reasoned programs. On the other hand, it failed to create a firm working-class base or to extend its influence much beyond Buenos Aires, mainly because of its inability to relate adequately to the needs of the proletariat and to the growth of nationalist sentiment. The analysis of these successes and failures also provides an important background for understanding the rise to power of Juan Perón and Peronism.
John Fante, an important figure in the history of the Italian-American novel, is proving to be fascinating to contemporary readers. Richard Collins has caught Fante's spirit from several crucial angles: as an ethnic writer; as a comic novelist; as a serious writer struggling to remain so in Hollywood. Intelligent, balanced, informative, and empathetic, this book combines criticism with scholarship, and biography with history to make what Henry James would have called a perfect 'literary portrait,' for it gives life to an interesting subject.
Packed with more than 500 techniques, this book delivers what you need to know-on the spot. It is suited to editors of all experience levels, whether you are: * Migrating from another NLE * Upgrading to Final Cut Studio 2 * Seeking a handy reference to raise your proficiency No need to wade through tomes of documentation. Final Cut Studio On the Spot presents immediate solutions in an accessible format. Step-by-step instruction by Apple Certified Pros shows you how to: * Optimize system performance * Create impressive titles with Generators, Motion, LiveType, and Photoshop * Build Commercial-quality transitions * Work quickly with buttons and keyboard shortcuts * Color correct to save vital shots, and keep them broadcast legal * Fix and mix for professional-quality audio * Use the compositing tools of master editors * Design and import graphics seamlessly * Integrate with other applications including Motion, Soundtrack Pro and Color * Troubleshoot and recover files * Manage media and backup strategies * Export and publish finished projects to tape, DVD, or the Web
Exposure to stressful life experiences can disrupt key regulatory systems in the body and contribute to a variety of negative health outcomes. This authoritative text takes a biopsychosocial approach to understanding the role of stress in alcohol use disorder, posttraumatic stress disorder, depression, cardiovascular disease, type 2 diabetes, cancer, and other chronic diseases. It presents cutting-edge knowledge about how stressors are conceptualized and measured; connections to disease processes; systemic racism as a significant, ongoing stressor for people of color; and factors that promote resilience. For each of the disorders discussed, proven and promising stress-targeted clinical interventions are reviewed. Student-friendly features include an end-of-book glossary and an extensive bibliography to facilitate in-depth study of selected topics of interest.
Stress has been recognized as an important factor in the development or recurrence of various mental disorders, from major depressive disorder to bipolar disorder to anxiety disorders. Stressful stimuli also appear to exert their effects by acting upon individuals with susceptible genotypes. Over the past 50 years, animal models have been developed to study these dynamic interactions between stressful stimuli and genetically susceptible individuals during prenatal and postnatal development and into adulthood. Stress and Mental Disorders: Insights from Animal Models begins with a discussion of the history of psychiatric diagnosis and the recent goal of moving toward precision psychiatry, followed by a review of clinical research on connections between stressful stimuli and the development of psychiatric disorders. Chapters are also included on neuroendocrine, immune, and brain systems involved in responses to stress. Additional chapters focus on the development of animal models in psychiatry and the susceptibility of the developing organism to stressful stimuli. Subsequent chapters are devoted to animal models of specific stress-sensitive psychiatric disorders, including schizophrenia, autism spectrum disorders, bipolar disorder, anxiety disorders, depression, and post-traumatic stress disorder. These chapters also focus on identification of promising molecular targets for development of new drug therapies. The section concludes with a chapter on animal models of resilience to stress-induced behavioral alterations as a newer approach to understanding why some animals are susceptible to stress and others are resilient, even though they are essentially genetically identical. The final chapter discusses how these basic laboratory studies are providing promising leads for future breakthroughs in the diagnosis, treatment, and prevention of mental disorders.
Probabilistic models are becoming increasingly important in analysing the huge amount of data being produced by large-scale DNA-sequencing efforts such as the Human Genome Project. For example, hidden Markov models are used for analysing biological sequences, linguistic-grammar-based probabilistic models for identifying RNA secondary structure, and probabilistic evolutionary models for inferring phylogenies of sequences from different organisms. This book gives a unified, up-to-date and self-contained account, with a Bayesian slant, of such methods, and more generally to probabilistic methods of sequence analysis. Written by an interdisciplinary team of authors, it aims to be accessible to molecular biologists, computer scientists, and mathematicians with no formal knowledge of the other fields, and at the same time present the state-of-the-art in this new and highly important field.
The increasing integration between gene manipulation and genomics is embraced in this new book, Principles of Gene Manipulation and Genomics, which brings together for the first time the subjects covered by the best-selling books Principles of Gene Manipulation and Principles of Genome Analysis & Genomics. Comprehensively revised, updated and rewritten to encompass within one volume, basic and advanced gene manipulation techniques, genome analysis, genomics, transcriptomics, proteomics and metabolomics Includes two new chapters on the applications of genomics An accompanying website - www.blackwellpublishing.com/primrose - provides instructional materials for both student and lecturer use, including multiple choice questions, related websites, and all the artwork in a downloadable format. An essential reference for upper level undergraduate and graduate students of genetics, genomics, molecular biology and recombinant DNA technology.
The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics. Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis. - Unique coverage of probabilistic reasoning methods applied to bioinformatics data--those methods that are likely to become the standard analysis tools for bioinformatics. - Shares insights about when and why probabilistic methods can and cannot be used effectively; - Complete review of Bayesian networks and probabilistic methods with a practical approach.
This impressive compilation offers a nearly complete listing of sound recordings made by American minority artists prior to mid-1942. Organized by national group or language, the seven-volume set cites primary and secondary titles, composers, participating artists, instrumentation, date and place of recording, master and release numbers, and reissues in all formats. Because of its clear arrangements and indexes, it will be a unique and valuable tool for music and ethnic historians, folklorists, and others.
Designed for portability and quick reference, Pocket Anesthesia, Fifth Edition, provides the essential information needed by practitioners and trainees on a daily basis. Expertly edited by Drs. Richard D. Urman and Jesse M. Ehrenfeld, this fully updated volume provides a concise and focused review of all areas of anesthesiology in one easy-to-navigate, pocket-sized notebook, making it an ideal reference for residents, anesthesiologists, CRNAs, CAA’s and students, in all clinical settings where anesthesia care is delivered.
Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.
With the first draft of the human genome project in the publicdomain and full analyses of model genomes now available, thesubject matter of 'Principles of Genome Analysis and Genomics' iseven 'hotter' now than when the first two editions were publishedin 1995 and 1998. In the new edition of this very practical guideto the different techniques and theory behind genomes and genomeanalysis, Sandy Primrose and new author Richard Twyman provide afresh look at this topic. In the light of recent excitingadvancements in the field, the authors have completely revised andrewritten many parts of the new edition with the addition of fivenew chapters. Aimed at upper level students, it is essential thatin this extremely fast moving topic area the text is up to date andrelevant. Completely revised new edition of an establishedtextbook. Features new chapters and examples from exciting new researchin genomics, including the human genome project. Excellent new co-author in Richard Twyman, also co-author ofthe new edition of hugely popular Principles of GeneManipulation. Accompanying web-page to help students deal with this difficulttopic at www.blackwellpublishing.com/primrose
In this highly original study of Italian baroque master Guido Reni (1575-1642), Richard Spear paints a compelling portrait of the artist - his complexities, his formative experiences, his cultural surroundings, and his unique sensibilities. Spear views Reni's career from a wide variety of perspectives and sets his life and works in social, economic, historical, artistic, religious, and psychological contexts. The author focuses first on Reni's peculiar character: a man at once deeply religious, rabidly misogynist, reportedly virginal, neurotically fearful of witches, and addicted to gambling. The author considers the enduring charisma of Reni's Crucifixions, weeping Marys, and repentant saints in the light of the Catholic doctrinal meaning of grace in Reni's time, the Church's attitude toward Mary and women, and the gendered implications of visual grace. Chapters on Reni's pricing policies, selling strategies, use of assistants, and attitude toward what constituted an "original", expose the motivating importance of money for Reni, and the concerns, even among seventeenth-century collectors, about how to distinguish original paintings from studio replicas or copies. The book investigates the ways renaissance and baroque attitudes toward art-making affected Reni and closes with a fresh view of Reni's unfinished canvases and last style, including the Divine Love, the beautiful and unusual painting that remained in Reni's studio at the time of his death.
American business folklore is awash with the adventures of successful entrepreneurs. Still, most of these stories are about Americans, neglecting important and courageous entrepreneurs from other countries. Made in Korea recounts the story of how Chung Ju Yung rose from poverty to build one of the world's largest and most successful building empires - Hyundai - through a combination of creative thinking, tenacity, timing, political skills, and a business strategy that few competitors ever understood. Chung entered the shipbuilding business with no experience and went on to create the world's largest shipyard. He began making automobiles when foreign experts unanimously predicted he would fail, and he started a global construction company that has built some of today's greatest architectural wonders. He even convinced the International Olympic Committee to select South Korea over Japan as the site for the highly successful 1988 Olympics. Unlike most CEO's of major firms, Chung has always preferred the company of his workers to that of the global executive elite. Hard work, creativity and a capacity to never give up - this is the essence of Chung's life. In each of his ventures, he exhibited a sheer determination to succeed, regardless of the obstacles, and he worked tirelessly to instil this drive in all of his employees. Even today, in the midst of Korea's worst economic crisis in over four decades, Chung's company is busy implementing plans to emerge as an even stronger contender in the world economy. Illustrated with 32 pages of colour photographs not previously seen in the West, including photos of Chung's recent historic visit to North Korea in 1998, Made in Korea takes stock of Chung's entire life, highlighting both his contributions to society and the lessons his work can teach to aspiring entrepreneurs.
Informed by discussions and interviews with more than fifty seasoned foreign and American negotiators, this landmark study offers a rich and detailed portrait of the negotiating practices of American officials. Including contributions by eleven international experts, i assesses the multiple influences--cultural, institutional, historical, and political--that shape how American policymakers and diplomats approach negotiations with foreign counterparts and highlights behavioral patterns that transcend the actions of individual negotiators and administrations.
The sixth edition of this comprehensive yet concise Rosen & Barkin’s 5 Minute Emergency Medicine Consult pulls together up-to-date and evidence-based practice guidelines for easy use in a busy emergency department. In just two brief, bullet-friendly, clutter-free pages, you can quickly decipher the information you need to confirm your diagnosis, order tests, manage treatment and more!
Without domestication, civilization as we know it would not exist. Since that fateful day when the first wolf decided to stay close to human hunters, humans and their various animal companions have thrived far beyond nearly all wild species on earth. Tameness is the key trait in the domestication of cats, dogs, horses, cows, and other mammals, from rats to reindeer. Surprisingly, with selection for tameness comes a suite of seemingly unrelated alterations, including floppy ears, skeletal and coloration changes, and sex differences. It’s a package deal known as the domestication syndrome, elements of which are also found in humans. Our highly social nature—one of the keys to our evolutionary success—is due to our own tameness. In Domesticated, Richard C. Francis weaves history and anthropology with cutting-edge ideas in genomics and evo devo to tell the story of how we domesticated the world, and ourselves in the process.
This book mainly presents the current state of knowledge on the use of of Silicon (Si) in agriculture, including plants, soils and fertilizers. At the same time, it discusses the future interdisciplinary research that will be needed to further our knowledge and potential applications of Si in agriculture and in the environmental sciences in general. As the second most abundant element both on the surface of the Earth’s crust and in soils, Si is an agronomically essential or quasi-essential element for improving the yield and quality of crops. Addressing the use of Si in agriculture in both theory and practice, the book is primarily intended for graduate students and researchers in various fields of the agricultural, biological, and environmental sciences, as well as for agronomic and fertilizer industry experts and advisors. Dr. Yongchao Liang is a full professor at the College of Environmental and Resource Sciences of the Zhejiang University, Hangzhou, China. Dr. Miroslav Nikolic is a research professor at the Institute for Multidisciplinary Research of the University of Belgrade, Serbia. Dr. Richard Bélanger is a full professor at the Department of Plant Pathology of the Laval University, Canada and holder of a Canada Research Chair in plant protection. Dr. Haijun Gong is a full professor at College of Horticulture, Northwest A&F University, China. Dr. Alin Song is an associate professor at Institute of Agricultural Resources and Regional Planning, Chinese Academy of Agricultural Sciences, Beijing, China.
Trusted by physicians and advanced practice providers through ten standard-setting editions, Fanaroff and Martin's Neonatal-Perinatal Medicine, 11th Edition, remains the reference of choice for expert, multidisciplinary guidance on the management and evidence-based treatment of problems in the mother, fetus, and neonate. An expanded team of international authors, led by Drs. Richard J. Martin, Avroy A. Fanaroff, and Michele C. Walsh of Rainbow Babies and Children's Hospital, brings you up to date with advances in the control of nosocomial infections in preterm infants, genetic disorders and birth defects, the fetal origins of adult disease, the late preterm infants, and much more – all designed to help you improve the quality of life and long-term outcomes of your patients. - Helps you make informed clinical choices for each patient – from diagnosis and treatment selection through post-treatment strategies and management of complications – with a dual focus on neonatology and perinatology. - Includes a new chapter on Social and Economic Contributors to Neonatal Outcome. - Features extensive updates and reorganization throughout, with new Key Points at the end of each chapter - Provides up-to-date, evidence-based content, with more information on precision medicine and genetics. - Uses detailed, full-color illustrations that depict disorders in the clinical setting and explain complex information. - Remains the most comprehensive, multidisciplinary text in the field – an excellent source of information for every stage of your practice.
Over the past 40 years, ERCP has become an effective therapeutic modality with diagnostic purposes that are continually improved.. The 3rd Edition of this practical reference helps you make the most of today's endoscopic retrograde cholangiopancreatography in your practice. You'll find authoritative, highly illustrated guidance on every aspect of ERCP, including coverage of the latest techniques. - Clearly depicts each step of ERCP procedures in dozens of step-by-step videos, including Needle Knife Sphincterotomy, Biliary Sphincterotomy, Cannulation, and Fistulotomy. - Provides clear guidelines on when and when not to perform ERCP. - Features superb, full-color images, and a wealth of illustrative diagrams. - Includes new chapters that cover duodenoscope reprocessing; endomicrocopy; EUS-guided endotherapy related to pancreatobiliary disorders; and CT and MRCP related to pancreatobiliary disorders. - Contains updated information on radiofrequency ablation for cancer, percutaneous vs. endoscopic drainage, scope cleaning practices, and pancreatic necrosis. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
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