This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.
This textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies and on patient care. The international team of contributors discuss the clinical course of multiple sclerosis, its clinical heterogeneity, the presence of subclinical disease activity which occurs during the early stages of the disease. Multiple sclerosis presents clinical challenges: from unexpected and irregular relapses to profressive deterioration.
Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.
Principles of Addiction Medicine, 7th ed is a fully reimagined resource, integrating the latest advancements and research in addiction treatment. Prepared for physicians in internal medicine, psychiatry, and nearly every medical specialty, the 7th edition is the most comprehensive publication in addiction medicine. It offers detailed information to help physicians navigate addiction treatment for all patients, not just those seeking treatment for SUDs. Published by the American Society of Addiction Medicine and edited by Shannon C. Miller, MD, Richard N. Rosenthal, MD, Sharon Levy, MD, Andrew J. Saxon, MD, Jeanette M. Tetrault, MD, and Sarah E. Wakeman, MD, this edition is a testament to the collective experience and wisdom of 350 medical, research, and public health experts in the field. The exhaustive content, now in vibrant full color, bridges science and medicine and offers new insights and advancements for evidence-based treatment of SUDs. This foundational textbook for medical students, residents, and addiction medicine/addiction psychiatry fellows, medical libraires and institution, also serves as a comprehensive reference for everyday clinical practice and policymaking. Physicians, mental health practitioners, NP, PAs, or public officials who need reference material to recognize and treat substance use disorders will find this an invaluable addition to their professional libraries.
This revised textbook examines the most important aspects of multiple sclerosis that impact on clinical trial design, on the development of new disease therapies, and, most importantly, on patient care. An international team of contributors discusses the clinical course of multiple sclerosis, its clinical heterogeneity, and the presence of subclinical disease activity which occurs during the early stages of the disease. There have been substantial advances in the field since the first edition was published in 1999. There are new chapters on functional imaging, the issues involved in long-term follow-up studies, cyclophosphamide, sex hormones and pregnancy-related factors, complementary and alternative treatments, management of cognitive impairment, treatment of pain, and rehabilitative approaches. Chapters on MS pathogenesis, imaging, the interferons, glatiramer acetate, mitoxantrone, IVIg, plasma exchange, stem cell transplantation, combination therapies, and newly-emerging treatments have been updated. This book is essential for any clinician who works with MS patients.
STATISTICAL THINKING FOR NON-STATISTICIANS IN DRUG REGULATION Statistical methods in the pharmaceutical industry are accepted as a key element in the design and analysis of clinical studies. Increasingly, the medical and scientific community are aligning with the regulatory authorities and recognizing that correct statistical methodology is essential as the basis for valid conclusions. In order for those correct and robust methods to be successfully employed there needs to be effective communication across disciplines at all stages of the planning, conducting, analyzing and reporting of clinical studies associated with the development and evaluation of new drugs and devices. Statistical Thinking for Non-Statisticians in Drug Regulation provides a comprehensive in-depth guide to statistical methodology for pharmaceutical industry professionals, including physicians, investigators, medical science liaisons, clinical research scientists, medical writers, regulatory personnel, statistical programmers, senior data managers and those working in pharmacovigilance. The author’s years of experience and up-to-date familiarity with pharmaceutical regulations and statistical practice within the wider clinical community make this an essential guide for the those working in and with the industry. The third edition of Statistical Thinking for Non-Statisticians in Drug Regulation includes: A detailed new chapter on Estimands in line with the 2019 Addendum to ICH E9 Major new sections on topics including Combining Hierarchical Testing and Alpha Adjustment, Biosimilars, Restricted Mean Survival Time, Composite Endpoints and Cumulative Incidence Functions, Adjusting for Cross-Over in Oncology, Inverse Propensity Score Weighting, and Network Meta-Analysis Updated coverage of many existing topics to reflect new and revised guidance from regulatory authorities and author experience Statistical Thinking for Non-Statisticians in Drug Regulation is a valuable guide for pharmaceutical and medical device industry professionals, as well as statisticians joining the pharmaceutical industry and students and teachers of drug development.
Reprints. Lists originally published in the Magazine of Virginia genealogy, February 1984-August 1986; Interpreting headrights in Colonial-Virginia patents: uses and abuses originally published September 1987 in National Genealogical Society quarterly.
An Introduction to Young Children with Special Needs: Birth Through Age Eight is a comprehensive introduction to educational policies, programs, practices, and services for future practitioners serving young children with delays or disabilities in early intervention-early childhood special education (EI-ECSE). Thoughtfully addressing the needs of children at risk for learning or development delays or disabilities, revered authors Richard M. Gargiulo and Jennifer L. Kilgo offer evidence-based interventions and instructional techniques that provide students with a broad understanding of important theoretical and philosophical foundations, including evidence-based decision making, developmentally appropriate practices, cultural responsiveness, and activity-based intervention. The Fifth Edition includes the latest developments in and influences on the field of early intervention and early childhood special education, including the Division for Early Childhood’s (DEC)Recommended Practices, which are infused throughout the text. With the support of this current and innovative book, readers will gain a firm understanding of the complex field of EI-ECSE to assist them in their future study and careers. A Complete Teaching & Learning Package SAGE Premium Video Included in the interactive eBook! SAGE Premium Video tools and resources boost comprehension and bolster analysis. Interactive eBook Your students save when you bundle the print version with the Interactive eBook (Bundle ISBN: 978-1-5443-6571-8), which includes access to SAGE Premium Video and other multimedia tools. SAGE coursepacks SAGE coursepacks makes it easy to import our quality instructor and student resource content into your school’s learning management system (LMS). Intuitive and simple to use, SAGE coursepacks allows you to customize course content to meet your students’ needs. SAGE edge This companion website offers both instructors and students a robust online environment with an impressive array of teaching and learning resources.
Written by the multidisciplinary intensive care unit staff at the Massachusetts General Hospital, the Fifth Edition of this best-selling handbook is a practical, complete, and current guide to medical and surgical critical care. In a user-friendly outline format designed for rapid reference, this pocket-sized book presents reliable, hospital-tested protocols that reflect today's most advanced critical care practices. This edition includes new chapters on disaster preparedness in the ICU, quality improvement and prophylaxis, non-antibiotic therapies for sepsis, and use of ultrasound in the ICU. An appendix provides supplemental drug information.
In Cytokines and the CNS, leading practicing physicians and scientists review the current status of cytokines, with an emphasis on their role in developmental and pathological processes in the central nervous system (CNS). They describe various cytokine families and their receptors, focusing on the delineation of known mechanisms by which ligand-receptor interactions mediate biological effects. The book also emphasizes interactions between cytokines and other biological regulators at the cellular and molecular level, and considers in detail tissue-specific effects exerted on CNS cells by cytokines. Cytokine regulation of CNS development also is discussed. With this background, Cytokines and the CNS then explores how cytokine action may be implicated in various human disease processes, including inflammation, neoplasia, degeneration, and the neurological manifestations of HIV infection. This book features cutting-edge information in this rapidly expanding area of investigation - the result of explosive growth in the understanding of cytokines' role in hematopoiesis, inflammation, and immunity, combined with tremendous advances in the identification and characterization of neurotrophic factors. Cytokines and the CNS contains chapters by practicing researchers from the fields of neurobiology and immunology/hematopoiesis, and presents both practical and conceptual information.
This voluminous book of 47 chapters offers a good cross section of what is burgeoing in the field of client-centered and experiential psychotherapy on the threshold of the nineties. it does not represent a single vision but gives the floor to the various suborientations: classics Rogerians; client-centered therapists who favor some form of integration or even eclecticism; experiential psychotherapists for whom Gendlin's focusing approach is a precious way of working; client-centered therapists who look at the therapy process in terms of information-processing; existentially oriented therapists... Remarkable is that - for the first time in the history of client-centered/experiential psychotherapy - the European voice rings through forcefully: more than half of the contributions were written by authors from Western Europe.Several chapters contain reflections on the evolution--past, present, and future--of client-centered/experiential psychotherapy. The intensive research into the process, which had a central place in the initial phase of client-centered therapy, is given here ample attention, with several creative studies and proposals for renewal. In numerous contributions efforts are made to build and further develop a theroy of psychopathology, the client's process, the basic attitudes and task-oriented interventions of the therapist. The chapters dealing with clinical practice typically aim at the description of therapy with specific client populations and paricularly severely disturbed clients. And finally a few fields are introduced which are new or barely explored within the client-centered/experiential approach: working with dreams, health psychology, couple and family therapy.
In the midst of an addiction epidemic, this newly updated edition of The American Society of Addiction Medicine Principles of Addiction Medicine, 5th edition is the sought-after text every addiction researcher and care provider needs. This comprehensive reference text dedicates itself to both the science and treatment of addiction. You’ll receive a thorough grounding in both the scientific principles behind the causes of addiction and the practical aspects of clinical care. Chapters are written by recognized experts, covering areas such as the basic science of addiction medicine; diagnosis, assessment and early intervention; pharmacologic and behavioral interventions; mutual help and twelve-step; and co-occurring addiction, medical and psychiatric disorders—backed by the latest research data and successful treatment methods. Features: Numerous figures, tables and diagrams elucidate the text Chapters include case examples List of data research reports provided at end of each chapter NEW material on Prescription Drug Abuse, Club Drugs, Nursing Roles in Addressing Addiction, Conceptual and Treatment Issues in Behavioral Addictions, Rehabilitation Approaches to Pain Management, Comorbid Pain and Addiction, Pharmacotherapy for Adolescents with Substance Use Disorders, Preventing and Treating Substance Use Disorders in Military Personnel, and more.
This book describes, illustrates, and shares our current understanding, evaluation, and treatments of nystagmus in infancy and childhood. Nystagmus in Infancy and Childhood will provide clinicians with algorithms for examination, descriptions of diagnostic techniques, and medical, surgical, and alternative treatments of the visual system in infants and children with nystagmus.
This volume contains abstracts of most of the significant scientific literature dealing with prostaglandins published between 1906~when certain biologically active tissue extracts first stimulated the speculation of researchers~and 1970~when the use of prostaglandins for experimental control of fertility and induction of labor had been reported from six countries. Of the more than 4000 articles now identified which were published between 1906 and 1972, approximately half had appeared in print by the end of 1970. A second volume will cover the material printed in 1971 and 1972 with special emphasis on the role of prostaglandins in reproductive physiology. The reasons for publishing this considerable compilation of data are twofold. On the one hand, prosta· glandins, a family of fatty acid derivatives first identified in human semen, have been shown to have great and varied effects on all aspects of human physiology due to activity at the cellular level as mediators in the formation of cyclic AMP. The study of prostaglandins is considered today one of the most promising fields in the biological sciences. Secondly, as is now recognized, prostaglandins play an important role in reproduction, influencing both male and female fertility. It is hoped that this volume will make the results of early prostaglandin research available to investigators throughout the world, including especially those in developing coun· tries who may not have easy access to such material.
A Practical Reference Guide to Emergency Care Essentials of Emergency Medicine, Second Edition, provides physicians and medical residents with a comprehensive reference guide to the practice of emergency medicine in clinical settings. Covering both complicated and straightforward issues, Essentials of Emergency Medicine, Second Edition, serves as a quick-reference handbook for the full range of challenges encountered in emergency departments, as well as a manual for physician self-assessment and study guide for those seeking recertification. This second edition, compiled by an editorial board of veteran emergency medicine providers, draws expert content from 184 contributors. New and updated chapters include expanded sections on pediatrics and toxicology as well as the latest science on emergency psychiatric care. With Essentials of Emergency Medicine, Second Edition, physicians and medical residents can readily assess and expand their knowledge of emergency medicine, ensuring their patients receive the highest quality care over the full continuum of treatment, from the emergency room to inpatient departments.
This popular reference is the definitive guide on exam techniques for neurology residents, fellows, and practitioners, integrating details of neuroanatomy and diagnosis in an easy-to-read, easy-to-follow format. A new clinical focus, new videos online, and new illustrations makeDeJong’s The Neurologic Examination, 8th Edition,even more useful for mastery of this complex area. Anatomical and exam illustrations ensure proper technique, and illustrative case studies and tables summarize differentials and clinical findings.
Based upon the testimony of Thomas Carlyle, most biographers acknowledge that Wordsworth witnessed the beheading of the journalist Antoine Gorsas in October 1793 during the Reign of Terror. But they go no further. This study reads the Poet’s reactions to the Terror in passages from The Prelude as explicitly about his twenty-three-year-old-self witnessing the gory deaths of Gorsas and others, which caused post-traumatic stress disorder and its symptoms, exacerbated by guilt for abandoning his French lover and their child a year earlier. Following a chronological arc from October 1793, when the trauma began, until its conclusion in October 1803, when Wordsworth became a poet-soldier, I examine poetic works from The Borderers (1796), the “Discharged Soldier’ (1798), the Two-Part Prelude (1799), Home at Grasmere (1800), and the Liberty sonnets (1803), to follow the Poet working through anxiety, fear, and remorse to a resolution.
Miller takes readers on an eye-opening tour of psychotropic drugs, describing the various kinds, how they were discovered and developed, and how they have played multiple roles in virtually every culture.
The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development.Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
Journalism Beyond Orwell adapts and updates pioneering work by Richard Lance Keeble to explore George Orwell’s legacy as a journalist in original, critical – and often controversial – ways. Though best known as the author of Animal Farm and Nineteen Eighty-Four, Orwell was, throughout his career, a journalist. The essays in this collection explore Orwell’s important legacy: as a practising activist journalist critical of the dominant media; as a polemicist, essayist and novelist constantly concerned with issues relating to war and peace; as a literary journalist determined to make ‘political writing an art’; and as a writer who warned of the growing powers of the secret state. Through this highly individualistic essay collection that connects Orwellian themes to modern journalism, Richard Lance Keeble explores key topics, including: Orwell the ‘proto-blogger’ How Orwell put his political economy critique of the corporate press into practice Information warfare in an age of hyper-militarism The manufacture of the myth of heroic warfare in the reporting of the Afghan conflict The debates over the theory and practice of peace journalism The ethical challenges for journalists reporting on conflict The crucial role of the alternative media The pleasures and pitfalls of the celebrity profile This collection will be of particular interest to students and researchers in journalism studies, English literature, media, intelligence studies and international relations.
An Introduction to Young Children With Delays and Disabilities: Birth Through Age Eight introduces readers to educational policies, services, and practices for future educators serving young children birth through age eight with delays and disabilities in early intervention/early childhood special education (EI/ECSE). Thoughtfully and comprehensively addressing the needs of young children and their families, esteemed authors Richard M. Gargiulo and Jennifer L. Kilgo offer interventions and instructional techniques that provide students with a broad understanding of important theoretical and philosophical foundations, including evidence-based decision making, cultural and linguistic responsiveness, and appropriate instruction and interventions in classroom settings and beyond. The Sixth Edition has been thoroughly updated to incorporate the Initial Practice-Based Professional Preparation Standards for Early Interventionists/Early Childhood Special Educators developed by the Division for Early Childhood (DEC) and Council for Exceptional Children (CEC) in 2020, as well as the DEC Recommended Practices. The revised text reflects these standards and practices in crucial content around assessment processes, partnering with families, teaming and collaboration, and services in natural environments, among many other updates to provide contemporary information and resources for future educators.
The Art of The Faerie Queene is the first book centrally focused on the forms and poetic techniques employed by Spenser. It offers a sharp new perspective on Spenser by rereading The Faerie Queene as poetry which is at once absorbing, demanding and experimental. Instead of the traditional conservative model of Spenser as poet, this book presents the poem as radical, edgy and unconventional, thus proposing new ways of understanding the Elizabethan poetic Renaissance. The book moves from the individual words of the poem to metre, rhyme and stanza form onto its larger structures of canto and book. It will be of particular relevance to undergraduates studying Elizabethan poetry, graduate students and scholars of Renaissance poetry, for whom the formal aspect of the poetry has been a topic of growing relevance in recent years.
Since 1975, Dr. Kenneth Swaiman’s classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that’s new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly. New content includes 12 new epilepsy chapters, 5 new cerebrovascular chapters, and 13 new neurooncology chapters, as well as new chapters on neuroimmunology and neuromuscular disorders, as well as chapters focused on clinical care (e.g., Counseling Families, Practice Guidelines, Transitional Care, Personalized Medicine, Special Educational Law, Outcome Measurements, Neurorehabilitation, Impact of Computer Resources, and Training Issues). Additional new chapters cover topics related to the developmental connectome, stem cell transplantation, and cellular and animal models of neurological disease. Greatly expanded sections to increase your knowledge of perinatal acquired and congenital disorders, neurodevelopmental disabilities, pediatric epilepsy, and nonepileptiform paroxysmal disorders and disorders of sleep. Coverage of new, emerging, or controversial topics includes developmental encephalopathies, non-verbal learning disorders, and the pharmacological and future genetic treatment of neurodevelopmental disabilities.
For more than 100 years, Henry's Clinical Diagnosis and Management by Laboratory Methods has been recognized as the premier text in clinical laboratory medicine, widely used by both clinical pathologists and laboratory technicians. Leading experts in each testing discipline clearly explain procedures and how they are used both to formulate clinical diagnoses and to plan patient medical care and long-term management. Employing a multidisciplinary approach, it provides cutting-edge coverage of automation, informatics, molecular diagnostics, proteomics, laboratory management, and quality control, emphasizing new testing methodologies throughout. Remains the most comprehensive and authoritative text on every aspect of the clinical laboratory and the scientific foundation and clinical application of today's complete range of laboratory tests. Updates include current hot topics and advances in clinical laboratory practices, including new and extended applications to diagnosis and management. New content covers next generation mass spectroscopy (MS), coagulation testing, next generation sequencing (NGS), transfusion medicine, genetics and cell-free DNA, therapeutic antibodies targeted to tumors, and new regulations such as ICD-10 coding for billing and reimbursement. Emphasizes the clinical interpretation of laboratory data to assist the clinician in patient management. Organizes chapters by organ system for quick access, and highlights information with full-color illustrations, tables, and diagrams. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Includes a chapter on Toxicology and Therapeutic Drug Monitoring that discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.
Netter's Neurology, 2nd Edition, by Drs. H. Royden Jones, Jayashri Srinivasan, Gregory J. Allam, and Richard A. Baker, uses visually rich Netter artwork to efficiently provide you with a concise overview of general neurology and its intersection with internal medicine, neurosurgery, ophthalmology, psychiatry, and orthopedics. "It communicates often very difficult areas of neurology quite simply, and builds on basics to advanced understanding. I've never seen such well-thought-out and informative illustrations with such detail in another neurology book of this type." - First Prize Winner, Illustrated Book Category, British Medical Association 2012 Medical Book Competition Master general neurology and its intersection with internal medicine, neurosurgery, ophthalmology, psychiatry, and orthopedics through comprehensive topic coverage. Get a quick and memorable overview of anatomy, pathophysiology, and clinical presentation from the precision and beauty of Netter and Netter-style plates that highlight key neuroanatomical and neurologic concepts. Explore specific clinical applications with vignettes included throughout the text that bring each topic to life. Find the information you need quickly and easily thanks to the short text and concise topic overviews. See the latest developments in the field in clear detail with new artwork and new entries on ALS, Eastern Equine Encephalitis, African Sleeping Sickness, and more. Effectively visualize the underlying anatomy in living patients through upgraded neuroimaging coverage, including MR, CT, and PET. Tap into additional treatment information with more clinical vignettes that provide "real-life" illustrative case evaluations.
Anesthesia Outside of the Operating Room is a comprehensive, up-to-date textbook that covers all aspects of anesthesia care in OOR settings, from financial considerations to anesthetic techniques to quality assurance. With increasing numbers of procedures such as cardiac catheterization and imaging taking place outside of the main OR, anesthesia providers as well as non-anesthesia members of the patient care team will find this book critical to their understanding of the principles of anesthesia care in unique settings which may have limited physical resources. Topics include patient monitoring techniques, pre-procedure evaluation and post-procedure care, and procedural sedation performed by non-anesthesia providers. The authors address problems of anesthesia that have unique answers in OOR settings, such as patient transport and cardiac arrest, and discuss technological progress and considerations for the future. The text also covers surgical procedures and anesthetic considerations by procedure location, such as radiology, infertility clinics, field and military environments, and pediatric settings, among many others Select guidelines from the American Society of Anesthesiologists (ASA) are provided as well. Edited by the senior faculty from Harvard Medical School and with contributions from other academic institutions, Anesthesia Outside of the Operating Room provides a unique and convenient compendium of expertise and experience.
Organized classically by system, this popular text gives medical and health professions students a complete, clinically oriented introduction to neuroanatomy. Each chapter begins with clear objectives, includes clinical cases, and ends with clinical notes, clinical problem-solving, and review questions. Hundreds of full-color illustrations, diagnostic images, and color photographs enhance the text. This Seventh Edition features new information relating the different parts of the skull to the brain areas, expanded coverage of brain development and neuroplasticity, and updated information on stem cell research. A companion Website includes the fully searchable text and 454 USMLE-style review questions with answers and explanations.
Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.
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