This publication offers both a timely reflection on the challenges faced and the approaches developed over the course of the pandemic and a look into the future at ways in which the skills and insights gained may bring about beneficial lasting changes in the teaching and learning of languages.
This book explains in practical detail how an understanding of competences can have an impact on all aspects of professional development. Areas covered include: • key terminology • factors leading to the development of teaching competence frameworks • in-depth exploration of the European Profiling Grid and the Eaquals Framework for Language Teacher Training and Development • practical advice on using language teaching competences for assessment and self-assessment in a range of teaching contexts
This essential guide examines course planning as an end-to-end process, from learners’ needs through to assessment, taking into account both the broader issues and the practical details at every stage. Areas covered include: • effective needs analysis • using the CEFR as a resource for course planning • writing scenarios for classroom teaching and assessment • triangulating course objectives, materials, and learners’ goals • key terminology Extra resources are available on the website: www.oup.com/elt/teacher/lcp Brian North is a co-author of the CEFR and of its companion volume, and was Chair of Eaquals from 2005 to 2010. Mila Angelova is the Academic Vice Chair of Eaquals and Head Director of Studies at AVO Language and Examination Centre, in Sofia. Elzbieta Jarosz is a member of the Eaquals Certification Panel and is the Academic Director of Gama College, in Krakow. Richard Rossner is a co-founder of Eaquals, and a co-author of the European Profiling Grid and the Eaquals Framework.
This book explores key issues in course management and provides an essential toolkit of practical and effective strategies for creating a positive teaching and learning environment.
This textbook aims to raise teachers’ language awareness, to emphasise the importance of language and communication in enabling young people to reach their potential, and to develop their knowledge of how language and communication function in educational environments as well as outside. Laid out in a clear five-unit structure, and complemented by a range of classroom activities, reflective exercises, and case study examples from around the world, this book addresses the need for teachers to become more linguistically aware and sensitive in an accessible and reader-friendly way. It is an essential resource for pre-service and in-service teachers working with a range of age groups across the curriculum.
Description: In biomedical research, because of a dramatic increase in productivity, immunocytochemistry has emerged as a major technique. The proposed book will provide the first practical guide to planning, performing, and evaluating immunocytochemical experiments. In today’s graduate education the emphasis is on doing research and not on formal class work. Graduate students therefore lack the background in many essential techniques necessary to perform research in fields in which they were not trained. As director of a university core microscopy facility which sees students and faculty from dozens of laboratories each year, Dr. Burry has surmised the vast majority of these novice microscope users need considerable help. In an attempt to educate users, Dr. Burry has initiated immunocytochemistry seminars and workshops which serve to train people in this powerful research tool. The proposed book is an outgrowth of these presentations and conversations with, by now, hundreds of people who have asked for help. The philosophy which separates this book from other books in this field is that it is practical, rather than academic. In looking at other important immunocytochemistry titles, the predominant orientation is academic, with the author attempting to comprehensively discuss the topic. For example, one book with sample preparation lists ten fixatives which can be used; however, only two such fixatives are commonly used today. In this particular title, the detailed discussion of old methods might be seen as important in establishing the author as an expert. By contrast, the approach for Burry’s book would be to discuss methods based on what works in animal research laboratories today, and focus only on the most productive methods. An additional distinction with this proposed book is the focus on animal research and not human pathology. There is a certification program for pathology technicians which requires them to learn a set body of material based on processing human tissue for examination by a pathologist. Many of the books on immunocytochemistry aim at this large pathology user base. Due to historical reasons, pathology laboratories process human tissues in a specific way and embed the tissue in paraffin, as has been done for over a century. In the last ten years, the power of immunocytochemistry in clinical diagnosis has become clear and has accordingly been adapted to pathology. However, the extensive processing needed for paraffin sections is not needed if the tissues are from research animals. Processing for animal-based tissues takes about a third of the time and results in higher quality images. The focus of this book is on processing these animal research tissues for immunocytochemistry. Today, there are no technique books which are aimed at this user base. As a subject matter expert in the area of the proposed book, Dr. Burry will make recommendations and offer opinions. Because this field is new and is emerging, there are numerous advantages of specific methods over other, more generalized methods. The purpose of this book is to show a novice how to do immunocytochemistry without engaging in a discussion of possible advanced methods. For the advanced user, there are several good books which discuss the unusual methods, yet for the novice there are currently none. Main Author : Richard W. Burry, The Ohio State University (United States). The Outline of the Book : Each chapter supplies a set of important principals and steps necessary for good immunocytochemistry. The information is distilled down to include only the most important points and does not attempt to cover infrequently used procedures or reagents. At the end of most chapters is a section on trouble-shooting many of the common problems using the Sherlock Holmes method. Each chapter also includes specific protocols which can be used. The goal of each chapter is to present the reader with enough information to successfully design experiments and solve many of the problems one may encounter. Using immunocytochemical protocols without the understanding of their workings is not advised, as the user will need to evaluate his or her results to determine whether the results are reliable. Such evaluation is extremely important for users who need reliable images which will clearly answer important scientific questions. 1. Introduction Definitions (immunocytochemistry and immunohistochemistry) Scope: animal research and not human pathology, paraffin sections, epitope retrieval, or immunohistochemistry Focus: fluorescence and enzyme detection Why do immunocytochemistry? Immunocytochemistry "individual study" rather than "population study" Example of a two-label experiment What is included in these chapters? Overview of the theory Background with enough information to help solve common problems. Advantages and disadvantages of different options Opinions and suggestions 2. Fixation and Sectioning Chemistry of fixation Denaturing vs cross-linking fixatives Application of fixative Perfusion, drop-in, cultures, fresh-frozen Selection of sample section type Sectioning tissue Rapid freezing, cryostat, freezing microtome, vibratome Storage of tissue Protocols 3. Antibodies Introduction Isoforms, structure, reactivity Generation Polyclonal vs monoclonal Antibodies as reagents Antibody specificity and sources Storage and handling 4. Labels for antibodies Fluorescence, enzymes and particulates Fluorescence theory Fluorescent labels - four generations Enzymes theory Selecting enzymes vs. fluorescence Selecting a label- advantages and disadvantages Protocols 5. Methods of applying antibodies Direct method Indirect method Antibody amplification methods ABC TSA Protocols 6. Blocking and Permeability Theory of blocking Theory of detergents Protocols 7. Procedure- Single primary antibody Planning steps Sample, fixation, sectioning Vehicle Antibody dilutions Controls Protocols 8. Multiple primary antibodies - primary antibodies of different species Procedure Controls Protocols 9. Multiple primary antibodies-primary antibodies of same species Block-between Zenon HRP-chromogen development High-titer incubations Controls Protocols 10. Microscopy Wide-field fluorescence microscope Confocal microscope Bright field—enzyme chromogen Choice Problems 11. Images Size, intensity, and pixels Manipulation—what is ethical? Manuscript Figures 11. Planning and Troubleshooting Scheme for discussion-making in planning experiments Case studies with Sherlock Holmes detective work 12. So you want to do electron microscopic ICC? Criteria in decision-making Summary of the two techniques
The mechanisms controlling body weight or, to be more specific, that component of body mass that consists of adipose tissue is an active area of scientific research. Two stimuli can be discerned that give a sense of urgency to this research. The first is the data, from many sources, confirming an inexorable upward trend in the prevalence of overweight and obesity in developed countries. The picture in the emerging nations is unclear because of both a lack of appropriate survey data and the continued scourge of under nourishment among their poor. It is likely, however, that, throughout the world, wherever disposable income and food availability are high, obesity and overweight will be a continuing and increasing problem. The second driving force among researchers is the realization that, to date, there has been little success in either stemming the tide of individuals experiencing excessive adiposity or enabling them to recover a more desirable body weight and composition. Such are the problems. But significant progress in research into the origins and treatment of this condition is being made, and in recent years has been brisk. Technical advances (such as the ability to measure total energy expenditure in free-living individuals with good reliability), new and imaginative thinking and a determination not to be satisfied with hypotheses until they have been thoroughly challenged by experiment have yielded significant advances.
This book responds to the some of the twenty-first century's most assuming problems of our times: global warming, sub-national terrorism, natural resource depletion, and economic, environmental and financial crises. It finds short- and long-term solutions to these global woes by looking to the city as the fulcrum for introducing sustainability around the world. Beginning with an outline of a robust strategy of sustainable cities-or sustainable city-regions-that has emerged out of over two-and-a-half decades of theoretical and practical work, the authors show why these portentous problems can best be addressed at the local-regional scale. In the process, this book cuts through the received wisdom and popular misunderstandings about sustainability and peels away the conceptual fog and ideological confusion about the meaning of sustainability. Drawing upon extensive fieldwork in North America, Europe and Asia, the authors examine both strong and weak examples of sustainable city approaches that validate their distinctive urban sustainability strategy. They discover keen insights and important lessons in these case studies for sustainability practice across the globe, whether in small towns in the US and Canada, large cities in Europe or tiny Chinese villages in Asia. Their concluding chapter argues that only the road less travelled holds real promise of creating sustainable city-regions around the world guided by the toolkit of ecological and technological conviviality.
The concept of dilettantism has not always been associated with amateurism or superficiality. It played a significant role in French and German critical writing from the late eighteenth century until the fin de siecle, embracing notions such as apprenticeship, fruitful error, parody, aestheticism and scepticism. Attempts to define dilettantism in a binary relationship with art have often been defeated by a fundamental ambivalence towards its values. The major texts on the subject are Goethe and Schiller's unfinished 'dilettantism project' (1799) and Paul Bourget's essay on Ernest Renan (1882), although the term was also used by writers including Wieland, Baudelaire, Laforgue, Nietzsche, Hofmannsthal and Thomas Mann. In this wide-ranging study Richard Hibbitt provides the first book-length comparative analysis of the concept of dilettantism, tracing its chronological development and proposing a synthesis of its diverse aspects and values.
America’s emerging “fat war” threatens to pit a shrinking population of trim Americans against an expanding population of heavy Americans in raging policy debates over “fat taxes” and “fat bans.” These “fat policies” would be designed to constrain what people eat and drink – and theoretically crimp the growth in Americans’ waistlines and in the country’s healthcare costs. Richard McKenzie’s HEAVY! The Surprising Reasons America Is the Land of the Free—And the Home of the Fat offers new insight into the economic causes and consequences of America's dramatic weight gain over the past half century. It also uncovers the follies of seeking to remedy the country’s weight problems with government intrusions into people’s excess eating, arguing that controlling people’s eating habits is fundamentally different from controlling people’s smoking habits. McKenzie controversially links America’s weight gain to a variety of causes: the growth in world trade freedom, the downfall of communism, the spread of free-market economics, the rise of women's liberation, the long-term fall in real minimum wage, and the rise of competitive markets on a global scale. In no small way – no, in a very BIG way – America is the “home of the fat” because it has been for so long the “land of the free.” Americans’ economic, if not political, freedoms, however, will come under siege as well-meaning groups of “anti-fat warriors” seek to impose their dietary, health, and healthcare values on everyone else. HEAVY! details the unheralded consequences of the country's weight gain, which include greater fuel consumption and emissions of greenhouse gases, reduced fuel efficiency of cars and planes, growth in health insurance costs and fewer insured Americans, reductions in the wages of heavy people, and required reinforcement of rescue equipment and hospital operating tables. McKenzie advocates a strong free-market solution to how America's weight problems should and should not be solved. For Americans to retain their cherished economic freedoms of choice, heavy people must be held fully responsible for their weight-related costs and not be allowed to shift blame for their weight to their genes or environment. Allowing heavy Americans to shift responsibility for their weight gain can only exacerbate the country’s weight problems.
Wiley's landmark food chemistry textbook that provides an all-in-one reference book, revised and updated The revised second edition of The Chemistry of Food provides a comprehensive overview of important compounds constituting of food and raw materials for food production. The authors highlight food’s structural features, chemical reactions, organoleptic properties, nutritional, and toxicological importance. The updated second edition reflects the thousands of new scientific papers concerning food chemistry and related disciplines that have been published since 2012. Recent discoveries deal with existing as well as new food constituents, their origin, reactivity, degradation, reactions with other compounds, organoleptic, biological, and other important properties. The second edition extends and supplements the current knowledge and presents new facts about chemistry, legislation, nutrition, and food safety. The main chapters of the book explore the chemical structure of substances and subchapters examine the properties or uses. This important resource: • Offers in a single volume an updated text dealing with food chemistry • Contains complete and fully up-to-date information on food chemistry, from structural features to applications • Features several visual aids including reaction schemes, diagrams and tables, and nearly 2,000 chemical structures • Written by internationally recognized authors on food chemistry Written for upper-level students, lecturers, researchers and the food industry, the revised second edition of The Chemistry of Food is a quick reference for almost anything food-related as pertains to its chemical properties and applications.
Concepts, methods, and techniques—supported with practical, real-world examples The first book to cover the ISTQB® Certified Test Automation Engineer syllabus With real-world project examples – Suitable as a textbook, as a reference book for ISTQB® training courses, and for self-study This book provides a complete overview of how to design test automation processes and integrate them into your organization or existing projects. It describes functional and technical strategies and goes into detail on the relevant concepts and best practices. The book's main focus is on functional system testing. Important new aspects of test automation, such as automated testing for mobile applications and service virtualization, are also addressed as prerequisites for creating complex but stable test processes. The text also covers the increase in quality and potential savings that test automation delivers. The book is fully compliant with the ISTQB® syllabus and, with its many explanatory examples, is equally suitable for preparation for certification, as a concise reference book for anyone who wants to acquire this essential skill, or for university-level study.
Known for depicting alienation, frustration, and the victimization of the individual by impenetrable bureaucracies, Kafka's works have given rise to the term Kafkaesque. This encyclopedia details Kafka's life and writings. Included are more than 800 alphabetically arranged entries on his works, characters, family members and acquaintances, themes, and other topics. Most of the entries cite works for further reading, and the Encyclopedia closes with a selected, general bibliography.
This book engages the problem of how, in the 21st century, we are to speak about experiences of the extraordinary/anomalous/extreme which occur on a transhistorical and transcultural basis. Critical re-readings of seminal texts show how 20th-century theoreticians in the humanities sought to erase madness from their irrational subjects. This propensity to sanitize madness in the study of religions was mirrored by the instinct of psychiatrists to degrade religious experiences by reducing mad consciousness to psychosis or dissociation. Richard Saville-Smith introduces explanatory pluralism as a way of recognizing these disciplinary biases and mad studies as a way of negotiating this understanding. The disproportionate significance of madness in shaping the fabric of the human story can then be recovered from both erasure and dismissal to be given the recognition previously denied - as acute religious experiences. Acute Religious Experiences divides into three sections, beginning with re-readings of William James's pathological programme, Rudolf Otto's numinous, T. K. Oesterreich's possession, Mircea Eliade's shamanism, Walter Stace's mysticism, Walter Pahnke's psychedelic experience, and Abraham Maslow's peak experiences. These ideas are shown to constitute the beginnings of a fractured discourse on the irrational. In part two, contemporary psychiatry's Diagnostic and Statistical Manual (DSM) and Foucault's History of Madness are re-read to reposition madness as not necessarily pathological. This opens the way for the identification of acute religious experiences as a new holistic and post-colonial approach through which religious data can be organized and addressed on a comparative basis. In part three, The Gospel of Mark is re-read as a case study to demonstrate the novel insights which flow from the identification of acute religious experiences. Richard Saville-Smith draws on his own experiences of madness and his PhD from the School of Divinity at The University of Edinburgh to elucidate his research.
By 1972, President Richard Nixon had reached the heights of political power and popularity, only to self-destruct due to his role in a third-rate burglary called Watergate. Nixon resigned in disgrace, and, for the first time in history, Americans came to be led by an unelected President and Vice President -- Gerald Ford and Nelson Rockefeller. But Americans had much more on their minds than mere politics -- movies, TV, sports, earning a living, etc. Hollywood motion pictures, including The Godfather, Jaws, and Star Wars, captured their imaginations, while weekly TV shows such as All in the Family and Happy Days made them laugh, and Monday Night Football kept their competitive juices flowing. To no ones surprise, UCLA continued to win NCAA basketball championships, and such schools as Alabama, Arkansas, Michigan, Nebraska, Notre Dame, Oklahoma, Penn State, Texas, and USC remained dominant on the gridiron. And professional sports, thanks to such super-stars as BIllie Jean King, Kareem Abul-Jabbar, Henry Aaron, Jack Nicklaus, Muhammad Ali, Al Unser, and Terry Bradshaw, became more popular than ever. But who could have predicted at the beginning of the decade that a young high school dropout named John Travolta and a band called the Bees Gees would become the kings of Disco Dancing? Or that a peanut farmer from Georgia would be elected President during our Bicentennial Year?
The cruel power of misdirected words, artfully structured but spiritually empty and bearing the stamp of law or legalistic reasoning, is a persistent theme in the modern novel. Richard Weisberg, who has written extensively on both literature and law, explores the role of legalism and its abuses in eight major novels of the nineteenth and twentieth centuries. Beginning with Dostoevski and moving by way of trenchant analyses of Flaubert and Camus, Weisberg culminates his argument in a brilliantly revisionist reading of Melville's Billy Budd. In each of the novels treated, Weisberg sees a verbally gifted central character relying on wordiness to avoid or distort previously revealed truths. He argues that the malaise Nietzsche called ressentiment goads these characters to verbalizations that do violence to others and, ironically, indict their very creators. He identifies the legalistic theme as the major mode of iconoclasm in modern fiction and the source of its holocaustic vision. Writers, he reflects, viewed with profound skepticism their culture's tendency to substitute complex narrative formalism for earlier, absolute approaches to justice. In this, Weisberg concludes, their works anticipated the jurisprudential discourse of today. "The Failure of the Word is a creative, provocative, and learned work, written with style and feeling. Weisberg brings to bear on his core themes (the legalistic proclivity and ressentiment) a wide body of knowledge and thought in law and philosophy, literary history and theory."--Robert L. Jackson, Yale University
Of Richard Hugo's Making Certain It Goes On, David Wagoner has written: "Richard Hugo spared himself (and us) no pains or joys in making the wonderful, vigorous original poems brought together in this single collection. His was and is a very important voice in modern American poetry." Hugo was also an editor of the Yale Younger Poets series and a distinguished teacher and master of the personal essay. Now many of his essays have been assembled and arranged by Ripley Hugo, the poet's widow and a writer and teacher, and Lois and James Welch, writers and close friends of the poet. Together the essays constitute a compelling autobiographical narrative that takes Hugo from his lonely childhood through the war years and his working and creative life to an interview just before his death in 1982. William Matthews, also a friend of Hugo's, has written an introduction.
This title is directed primarily towards health care professionals outside of the United States. In the 21st Century, the management of type 2 diabetes has become even more important both in the primary health care setting and in the UK government's health policy. With the publication of the National Service Framework and the allied National Clinical Guidelines, both patients and the government expect practices to deliver appropriate and effective care to a high standard. This handbook addresses many concepts important in the day-to-day management of these patients. In addition to the discussion of specific medical management of type 2 diabetes (including the improvement of cardiovascular risk factors), the book explores the use of self-management techniques, the consultation process, and the use of psychological techniques to influence health-related behavior. All aspects of the text are linked, when appropriate, to the GMS contract. The authors include a full time GP delivering diabetic care and an eminent Consultant/academic at the leading edge of diabetes research The text is completely up-to-date with numerous current references, incorporating the latest guidance The span of the text is comprehensive, including clinical, organisational and psycho-social topics of importance in delivering high-quality diabetes care The text is cross-referenced to the relevant QOF indicators and NSF standards This book also covers the relevant aspects of diabetes in Curriculum Statement 15.6 prepared by the Royal College of General Practitioners, which forms the basis of the new membership examination and the competencies expected of General Practitioners. The management options include extensive balanced discussions about not just drugs, but also health education and appropriate referrals to specialists The approach is neither didactic nor promotional, and aims to provide sufficient practical information to help clinicians make optimal decisions that take full account of the latest authoritative guidance, but which can be tailored rationally to the individual patient's needs Many of the concepts covered - including reduction of cardiovascular risk, health education, audit and lifestyle - are extremely relevant to non-diabetes care The appendices include a detailed drug formulary and the relevant 2006-2008 QOF clinical indicators. Future trends and further reading are clearly set out, ensuring that the book will remain useful for the next few years.
Obesity in children and adolescents is a serious issue with many health and social consequences that often continue into adulthood. Implementing prevention programs and getting a better understanding of treatment for youngsters is important to controlling the obesity epidemic. The term "childhood obesity" may refer to both children and adolescents. Between 5-25 percent of children and teenagers in the United States are obese. As with adults, the prevalence of obesity in the young varies by ethnic group. It is estimated that 5-7 percent of White and Black children are obese, while 12 percent of Hispanic boys and 19 percent of Hispanic girls are obese. Some data indicate that obesity among children is on the increase. The second National Children and Youth Fitness Study found 6-9 year olds to have thicker skinfolds than their counterparts in the 1960s. During the same period, others documented a 54 percent increase in the prevalence of obesity among 6-11 year olds. This book examines leading research in this area of great concern to society.
Most physicians entering the field of pediatric cardiology are drawn to it by an interest in the wide variety of congenital heart defects which present at various ages. Most congenital heart disease will be evident in early life, presenting with cyanosis, heart murmur, congestive heart failure or shock. Textbooks in pediatric cardiology are filled overwhelmingly with chapters on the various congenital heart lesions which are encountered, both rare and common. However, practicing pediatric cardiologists will be quick to point out that a significant number of referrals to any practice do not involve congenital heart problems. Reviewing our own statistics at the Children’s Hospital of Michigan Cardiology Center for the past two years (2010-2012) reveals that outpatient visits for new patient consultations examined by age groups are: less than 1 year of age – 11%; 1-5 years – 23%; 6-10 years – 21%; 11-18 years – 45%. Retrospective data collected from billing codes, as in this brief survey, may imprecise. However, it does provide a snapshot of the usual referral problems encountered by pediatric cardiologists. In our practice, the most common overall reason for referral in all ages was "heart murmur", constituting 26% of total referrals. Second were rhythm and rhythm related problems (inclusive of palpitations, abnormal ECG and diagnosed premature beats) constituted 19% of the total. In the age group of interest for this book of 11-18 years, the most common presenting issues were rhythm related (23%) and chest pain (23%), followed by syncope or dizziness (19%) and heart murmur (12%). Congenital heart disease diagnoses encountered in the 11 to 18 year age group comprised only 6.5% of referrals within that age group. It is likely that many of these were not new diagnoses (with a few exceptions), but rather represented transfers to our practice. Our own outpatient clinical experience reveals that the majority of outpatients referred by pediatricians for pediatric cardiology evaluation are between the ages of 11 and 18. The majority of these new referrals are not for congenital heart disease. Our intent for this edition of Pediatric Clinics of North America is to describe the types of problems which seem to be of concern to the pediatric community within this age group and to describe strategies for evaluation.
This edition of Health Psychology provides an even more effective introduction to the psychology behind why we get sick, how we stay well, how we react to illness, and how we relate to the health care system and health care providers.
American author Richard Harding Davis began his career as a writer of short stories, but he first gained international acclaim as a daring war correspondent whose front-line dispatches left audiences breathless. In this eclectic collection, Harding Davis returns to his first literary love, the short story.
Organic Chemistry, Volume 18: The Chemistry of Indoles discusses the chemistry of indole derivatives. This book explores the potent biological activity of several indole derivatives and explains the structure of indole alkaloids. Organized into 10 chapters, this monograph starts with an overview of the most important types of reactions of the indole ring on a mechanical basis. This text then proceeds to review the methods of synthesizing indoles and describes the oxidations and rearrangements of indole derivatives. Other chapters explore the special features of the synthesis and reactivity of hydroxyindoles, acylindoles, and aminoindoles. This book discusses as well the properties of carboxyl groups, which is substituted on the benzenoid ring of the indole nucleus that is typical of aromatic carboxylic acids. The final chapter deals with the certain classes of indoles that are found in nature. Chemists, researchers, and readers interested in the chemistry of indoles will find this book extremely useful.
Over three editions the Handbook of Diabetes has built a reputation as an essential practical manual on the assessment and management of patients with diabetes. Previously written by Gareth Williams and John Pickup, the book has been completely revised by Rudy Bilous and Richard Donnelly to reflect recent changes in diabetes treatment and care. It contains information on the new IFCC units for measuring blood glucose and the latest drugs being used to combat diabetes, as well as alternative methods of insulin delivery. The book has been fully updated and redesigned to make it even more user-friendly, and contains case histories, practice points, and landmark clinical trials highlighted in color in each chapter where appropriate. It also features an entirely new set of 250 clinical photographs. The Handbook of Diabetes is the ideal practical handbook for all health professionals with an interest in diabetes care.
How does the brain regulate sexual behavior, or control our body weight? How do we cope with stress? Addressing these questions and many more besides, this thoroughly revised new edition reflects the significant advances that have been made in the study of neuroendocrinology over the last twenty years. The text examines the importance of the hypothalamus in regulating hormone secretion from the endocrine glands, describing novel sites of hormone release including bone, heart, skeletal muscle and liver. The role of steroid hormone, neurotransmitter and peptide receptors, and the molecular responses of target tissues, is integrated into the discussion of the neuroendocrine brain, especially through changes in gene expression. Particular attention is attached to neuropeptides, including their profound influence on behavior. Complete with new full-color figures throughout, along with review and essay questions for each chapter, this is an ideal resource for undergraduate and graduate students of neuroscience, psychology, biology and physiology.
With cutting-edge and clinically relevant information, MECHANICAL VENTILATION, 2nd Edition takes a practical, clinical approach to the principles and practice of mechanical ventilation. This informative resource explains mechanical ventilation decisions and procedures in real-world terms so information is easy to understand and apply. This thoroughly updated edition includes one new chapter, four completely updated chapters, and a wealth of new user-friendly features. - Detailed, clinically focused coverage of the application of mechanical ventilation to the most common respiratory diseases, provides practical answers to real life problems. - UNIQUE! Sections of chapters on Special Techniques and Future Therapies include information on the newest techniques for treating patients in respiratory distress. - A separate appendix of case studies helps you apply what you've learned to realistic situations. - Well-known and respected authors, Neil MacIntyre and Rich Branson, share their vast expertise and accurate, cutting-edge information. - Chapter Objectives, Key Point Summaries, and Assessment Questions reinforce basic concepts from each chapter. - New chapter on Unique Patient Populations highlights the mechanical ventilation issues of traumatic brain injury, neuromuscular disease, lung transplantation, burn injury, and perioperative patient populations. - Expanded glossary includes relevant terminology and key terms to help you easily find unfamiliar terminology.
In the course of the same old race I find myself writing about knowing some people—how fame seems to set some people apart from us, once known: I was astonished by Ernest Hemingway's small, weak handshake when we were introduced at Scribners by John Hall Wheelock and by the jolt of force with which Elie Wiesel squeezed my hand. How long ago seems knowing, too: when I first meet Isaac Singer he asks me, "Who is Mr. Saul Bellow?" We're on the Upper West Side in his apartment next to the funeral parlor. A yellow parakeet hops around on Singer's bald forehead. Singer's great comic story of faith, "Gimpel the Fool," has only recently been published from Yiddish into English in a translation by Saul Bellow. They're both still a long way from Stockholm. "Do you know him? Can you tell me who this Mr. Bellow is?" he asks. It was not always possible to guess Singer's motives in acting as though he was not impressed with worldly reputations. His features of a medieval Polish saint, even to a faint white-haired tonsure effect around the crown of his skull, were backlit by the glowing monitor from his mischievous incubus.—from the Preface These are Richard Elman's candid snapshots in prose of the various, mostly literary celebrities he encountered during his four decades as a working writer and journalist—among them Isaac Bashevis Singer, Tillie Olsen, Bernard Malamud, Faye Dunaway, Hunter S. Thompson, and other important artists and writers who were Elman's teachers and, occasionally, adversaries. Engagingly written and never superficial, these portraits and anecdotes in many cases strike to the center of each subject's art. To many readers, these persons are just "names"; Elman brings them to life while never simplifying or overdramatizing their work.
Contributors include Dapo Akande (Oxford), Antonio Franceschet (Acadia), Tracy Isaacs (Western Ontario), Catherine Lu (McGill), Darryl Robinson (The International Criminal Court), Michael P. Scharf (Case Western Reserve School of Law), Alex Tuckness (Iowa State), and David Wippman (Cornell).
The evolution of high-crowned teeth, hypsodonty, is a defining characteristic of many terrestrial herbivores. To date, the most prominent focus in the study of the teeth of grazing herbivores has been co-evolution with grasses and grasslands. This book develops the idea further and looks at the myriad ways that soil can enter the diet. Madden then expands this analysis to examine the earth surface processes that mobilize sediment in the environment. The text delivers a global perspective on tooth wear and soil erosion, with examples from the islands of New Zealand to the South American Andes, highlighting how similar geological processes worldwide result in convergent evolution. The final chapter includes a review of elodonty in the fossil record and its environmental consequences. Offering new insights into geomorphology and adaptive and evolutionary morphology, this text will be of value to any researcher interested in the evolution of tooth size and shape.
This book dissects the effects of ethanol on the major neurotransmitter systems affected by ethanol and correlates these actions with the behavioral consequences. The subject is approached first from the perspective of the neurochemical system and the behaviors resulting from ethanol's effects on that system. The behaviors themselves are discussed in later chapters. Some older theories of the effects of ethanol such as the membrane fluidization hypothesis are evaluated in light of new and updated information. Fetal Alcohol Syndrome (FAS) as well as the structural damage in the brain by long term ethanol exposure are also discussed.
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