Evidence-Based Otitis Media offers one-stop shopping for the best current evidence to guide management decisions at the individual, organizational, and societal levels. This text details the importance of evidence-based data in interpreting the ever-enlarging body of literature on otitis media. The editors have assembled an impressive group of experts on all aspects of otitis media and addressed comprehensively many issues related to methodology, clinical management, and consequences of this disease. The eight chapters comprising the methodology section provide the necessary background and detail to allow physicians and other health professionals to understand and appreciate the value of evidence-based medicine. Updates include: the incorporation of new original research, systemic reviews, and evidence reports to existing chapters. New chapter topics include: evidence-based medicine, professional evidence reports, molecular and translational research, complementary and alternative medicine, bacteriologic efficacy of antimicrobials, vaccine prevention, international management perspectives, meta-analysis of speech and language sequelae, suppurative complications, host susceptibility to sequelae, and judicious use of systemic and topical antimicrobials. FEATURES: *Maturation of evidence-based medicine as a foundation for clinical care is reflected throughout the text. *Extensive evidence tables summarize study characteristics and quantitative outcomes for clinically relevant endpoints *Internationally distinguished contributors selected based on both their clinical expertise and their ability to write for an evidence-based text
Nelson Textbook of Pediatrics has been the world’s most trusted pediatrics resource for nearly 75 years. Drs. Robert Kliegman, Bonita Stanton, Richard Behrman, and two new editors—Drs. Joseph St. Geme and Nina Schor—continue to provide the most authoritative coverage of the best approaches to care. This streamlined new edition covers the latest on genetics, neurology, infectious disease, melamine poisoning, sexual identity and adolescent homosexuality, psychosis associated with epilepsy, and more. Understand the principles of therapy and which drugs and dosages to prescribe for every disease. Locate key content easily and identify clinical conditions quickly thanks to a full-color design and full-color photographs. Access the fully searchable text online at www.expertconsult.com, along with abundant case studies, new references and journal articles, Clinics articles, and exclusive web-only content. Stay current on recent developments and hot topics such as melamine poisoning, long-term mechanical ventilation in the acutely ill child, sexual identity and adolescent homosexuality, age-specific behavior disturbances, and psychosis associated with epilepsy. Tap into substantially enhanced content with world-leading clinical and research expertise from two new editors—Joseph St. Geme, III, MD and Nina Schor, MD—who contribute on the key subspecialties, including pediatric infectious disease and pediatric neurology. Manage the transition to adult healthcare for children with chronic diseases through discussions of the overall health needs of patients with congenital heart defects, diabetes, and cystic fibrosis. Recognize, diagnose, and manage genetic conditions more effectively using an expanded section that covers these diseases, disorders, and syndromes extensively. Find information on chronic and common dermatologic problems more easily with a more intuitive reorganization of the section.
Covering both the theoretical and practical aspects of critical care,Irwin & Rippe’s Intensive Care Medicine, Ninth Edition, provides state-of-the-art, evidence-based knowledge for specialty physicians and non-physicians practicing in the adult intensive care environment. Drs. Craig M. Lilly, Walter A. Boyle, and Richard S. Irwin, along with a team of expert contributing authors and education expert, William F. Kelly, offer authoritative, comprehensive guidance from an interprofessional, collaborative, educational, and scholarly perspective, encompassing all adult critical care specialties.
This book discusses a broad range of statistical design and analysis methods that are particularly well suited to pollution data. It explains key statistical techniques in easy-to-comprehend terms and uses practical examples, exercises, and case studies to illustrate procedures. Dr. Gilbert begins by discussing a space-time framework for sampling pollutants. He then shows how to use statistical sample survey methods to estimate average and total amounts of pollutants in the environment, and how to determine the number of field samples and measurements to collect for this purpose. Then a broad range of statistical analysis methods are described and illustrated. These include: * determining the number of samples needed to find hot spots * analyzing pollution data that are lognormally distributed * testing for trends over time or space * estimating the magnitude of trends * comparing pollution data from two or more populations New areas discussed in this sourcebook include statistical techniques for data that are correlated, reported as less than the measurement detection limit, or obtained from field-composited samples. Nonparametric statistical analysis methods are emphasized since parametric procedures are often not appropriate for pollution data. This book also provides an illustrated comprehensive computer code for nonparametric trend detection and estimation analyses as well as nineteen statistical tables to permit easy application of the discussed statistical techniques. In addition, many publications are cited that deal with the design of pollution studies and the statistical analysis of pollution data. This sourcebook will be a useful tool for applied statisticians, ecologists, radioecologists, hydrologists, biologists, environmental engineers, and other professionals who deal with the collection, analysis, and interpretation of pollution in air, water, and soil.
In this exciting symposium, the editor brings to print important new information on AIDS and how HIV affects the brain. Each chapter focuses on one or more of the cell types that reside in or traffic through the central nervous system (CNS). Each of these cells is important to considerations of the pathogenesis of the CNS. Neurologists, AIDS physicians, and other professionals caring for AIDS patients will find that this “cell-based” view provides a unique perspective and that it will guide and stimulate future investigation of this clinically important and pathogenetically intriguing disorder. The editor also introduces some general considerations for therapeutic intervention of AIDS dementia complex (ADC). The contributors to The Cellular Basis of Central Nervous System HIV-1 Infection and the AIDS Dementia Complex deal with the cells and mechanisms involved in HIV-1 brain infection and the resultant ADC. Each author was asked to review the involvement of their assigned cells in CNS HIV-1 infection and how these cells might be involved in the pathology and process of brain injury associated with ADC. Readers will be enlightened on the functional roles of various cells and how these cells and mechanisms might fit into the broader picture of ADC pathogenesis.
This book examines the long term economic growth that has raised the West's material living standards to levels undreamed of by counterparts in any previous time or place. The authors argue that this growth has been driven by technological revolutions that have periodically transformed the West's economic, social and political landscape over the last 10,000 years and allowed the West to become, until recently, the world's only dominant technological force. Unique in the diversity of the analytical techniques used, the book begins with a discussion of the causes and consequences of economic growth and technological change. The authors argue that long term economic growth is largely driven by pervasive technologies now known as General Purpose (GPTs). They establish an alternative to the standard growth models that use an aggregate production function and then introduce the concept of GPTs, complete with a study of how these technologies have transformed the West since the Neolithic Agricultural Revolution. Early modern science is given more importance than in most other treatments and the 19th century demographic revolution is studied with a combination of formal models of population dynamics and historical analysis. The authors argue that once sustained growth was established in the West, formal models can shed much light on its subsequent behaviour. They build non-conventional, dynamic, non-stationary equilibrium models of GPT-driven growth that incorporate a range of phenomena that their historical studies show to be important but which are excluded from other GPT models in the interests of analytical tractability. The book concludes with a study of the policy implications that follow from their unique approach.
Published by Oxford University Press in 2008, Massacre at Mountain Meadows relied on new and exhaustive research to tell the story of one of the grimmest episodes in Latter-day Saint history. On September 11, 1857, southern Utah settlers slaughtered more than 100 emigrants of a California-bound wagon train. In this much-anticipated sequel, Richard E. Turley Jr. and Barbara Jones Brown follow up that volume with an examination of the aftermath of the atrocity. In greater detail than ever before, Vengeance Is Mine documents southern Utah leaders' attempts to cover up their crime by silencing witnesses and spreading lies about the victims and perpetrators of the crime. Investigations by both governmental and church bodies were stymied by stonewalling and political wrangling. While nine men were eventually indicted, five were captured and only one, John D. Lee, was executed. The book examines the maneuvering of the defense and prosecution in Lee's two trials, the second ending in Lee's conviction. The book examines the fraught relationship between Lee and church president Brigham Young, including what Young knew of the crime and when he knew it. The book also tells the story of the seventeen young children who survived the massacre and their later return to Arkansas, from where the ill-fated wagon train originated. The book traces the fate of the perpetrators to the end of their lives, including the harrowing demise of Nephi Johnson, who screamed, "Blood! Blood! Blood!" in the delirium of his death bed more than sixty years after the massacre"--
Written for safety and loss-control, environmental, and quality managers, this is the first comprehensive, integrated guide to developing a complete environmental risk analysis for regulated substances and processes. Unlike other books, Introduction to Risk Analysis looks at risk from a regulatory perspective, allowing both professionals in regulatory agencies concerned with risk_including OSHA, EPA, USDA, DOT, FDA, and state environmental agencies_and professionals in any agency-regulated industry to understand and implement the methods required for proper risk assessment. The authors examine risk and the structure of analysis. Emphasizing the predictive nature of risk, they discuss the quantitative nature of risk and explore quantitative-analysis topics, including data graphing, logarithmic thinking, risk estimating, and curve fitting. Chapters include discussions on functions, models, and uncertainties; the regulatory process; risk assessment; exposure; dosimetry; epidemiology; toxicology; risk characterization; comparative risk assessment; ecological risk assessment; risk management; and risk communication. Six in-depth case studies, an annotated bibliography, and more than 50 figures are also included.
This book was written for you-a graduate social work student-as an introduction to program evaluation. We selected and arranged its contents so it can be used in a beginning one-semester social work program evaluation course, a social work administrative course, or a program planning course. It is designed to prepare you to: Participate in evaluative activities within your social service organization, Become a beginning critical producer of the professional evaluative literature, Become a beginning consumer of the professional evaluative literature, Master more advanced evaluation courses and texts.
Tap into the gold standard on central nervous system infections: Infections of the Central Nervous System, 4e is now fully revised and updated to accommodate the wealth of new CNS information discovered over the past decade. More than 90 leading experts contribute chapters, providing comprehensive, up-to-date information. With a broad scope and thorough detail, the text addresses pathogenesis, clinical manifestations, diagnosis, and therapy of various CNS infections and related conditions. Features: Every chapter has been extensively revised and updated, nearly half with new author teams NEW chapter on acute encephalitis NEW clinical information on treatment of tuberculosis, non-tubercular mycobacterial infections, brain abscess, and Lyme disease NEW color design and color images Numerous diagrams, figures, tables, illustrations and photographs demonstrate the content Evidence-based references
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
Much has been written about the history and the people of northern Manitoba, but until now this body of work has not been readily accessible to the researcher or teacher. This bibliography identifies published sources, such as books and magazine and journal articles, as well as unpublished sources that are available to the public, including academic theses and government pamphlets, reports, and studies. It includes primarily materials dealing with the area north of 53rd parallel of latitude, but it also includes material on the area east of Lake Winnipeg as far south as the 51st parallel, a region that is similar to the North. References are listed under seven topics: bibliographies and research aids; the fur trade; Aboriginal and Métis populations; exploration and travel accounts; church and mission histories; northern geography and resources; and community histories and twentieth century resource exploitation.
Written by leading experts in the field, Stellar Spectral Classification is the only book to comprehensively discuss both the foundations and most up-to-date techniques of MK and other spectral classification systems. Definitive and encyclopedic, the book introduces the astrophysics of spectroscopy, reviews the entire field of stellar astronomy, and shows how the well-tested methods of spectral classification are a powerful discovery tool for graduate students and researchers working in astronomy and astrophysics. The book begins with a historical survey, followed by chapters discussing the entire range of stellar phenomena, from brown dwarfs to supernovae. The authors account for advances in the field, including the addition of the L and T dwarf classes; the revision of the carbon star, Wolf-Rayet, and white dwarf classification schemes; and the application of neural nets to spectral classification. Copious figures illustrate the morphology of stellar spectra, and the book incorporates recent discoveries from earth-based and satellite data. Many examples of spectra are given in the red, ultraviolet, and infrared regions, as well as in the traditional blue-violet optical region, all of which are useful for researchers identifying stellar and galactic spectra. This essential reference includes a glossary, handy appendixes and tables, an index, and a Web-based resource of spectra. In addition to the authors, the contributors are Adam J. Burgasser, Margaret M. Hanson, J. Davy Kirkpatrick, and Nolan R. Walborn.
When we were first approached by the senior editors of this series to edit a book on interactions between the host and infectious agents, we accepted this offer as an exciting challenge. The only condition, readily agreed upon, was that such a book should focus on the immunology of infections in humans. Our reasons, if not biases, were severalfold. We sensed that the fields of microbiology and im munology, which had diverged as each was focusing on its individual search, were coming together. In agreement with the opinions expressed by Dr. Richard Krause in the Introduction, we strongly believed that the development of the immune system evolved in response to infectious agents and that the evolution of these agents was influenced in turn by the character of the host's responses. An inten sive examination of the multitude of primitive or more recently developed host defense mechanisms to determine their relative contribution to man's resistance to a given infectious agent appeared to us to be of crucial basic and practical interest. Many immune mechanisms studied in animals were being explored in humans and it appeared timely to focus particularly on what was known about man's resistance to infectious agents, correlating this information with lessons learned from relevant experiments in animal models.
Linville argues that a new approach to the book of Kings is needed because of the failings of the usual historical-critical methods. He adopts a holistic approach which sees the book as a Persian-era text intended to articulate politically and religiously significant symbols within the book's monarchic history. These express the producer's reactions to important issues of Jewish identity in the continuing Diaspora and in Jerusalem. In the story of the schisms and apostacies of Israel's defunct monarchies both the Diaspora and cultural pluralism are legitimized. Rival versions of Israelite heritage are reconciled under an overarching sense of a greater Israelite history and identity.
Only six escapees survived the Sandakan death marches of 1945 in North Borneo, the worst atrocity ever inflicted on Australian soldiers. 1787 Australian and 641 British POWs perished. Previous descriptions of the numerous violent acts have yielded little understanding of a situation where the real struggle was to keep one’s humanity when so many were losing theirs, whether Allied POWs, local residents of Borneo, Javanese slave labourers, or Japanese soldiers. Understanding this extraordinary story is aided by reference to a wide range of sources in different countries and disciplines, and by examining the perspectives of all players in this terrible game of survival. An unusual and extreme POW story, the Sandakan tragedy had four stages: active resistance in 1942–3, stubborn endurance in 1943–4, the collapse of civilized existence in 1945 and, finally, the postwar decades of torment for the six damaged survivors, the gradual assimilation of the story, the healing of the damage and the commemoration of the tragedy by the families and communities involved. Richard Wallace Braithwaite’s father was one of the six survivors of the Sandakan death marches of 1945. He died in 1986, still wanting the story to be properly told. This led to a project that has lasted for much of the last forty years of the author’s life, culminating in this book. With a scientific background, Richard worked for many years with CSIRO and universities in the biological and social sciences and in historical research. His extensive and diverse research history and lifelong personal immersion in the story has given him a unique perspective in exploring the complexities of the Sandakan tragedy.
From the Publisher: Essentials of Global Health is just one offering in Jones and Bartlett's new Essential Public Health series. The book is a clear, concise, and user-friendly introduction to the most critical issues in global health. It illustrates key themes with an extensive set of case studies, examples, and the latest evidence. While the book offers a global perspective, particular attention is given to the health-development link, to developing countries, and to the health needs of poor and disadvantaged people. This introductory level textbook is perfect for undergraduate students and others new to the field of public health or global health. It is based on and designed for a one-semester global health course.
Public Health 101 provides a big-picture, population perspective on the determinants of health and disease and the tools available to protect and promote health. It examines the full range of options for intervention including use of the health care system, the public health system, and society-wide interventions such as laws and taxation.Students will learn how public health affects them in their everyday lives. Using case studies, vignettes, and extensive examples, they will learn and apply frameworks for thinking about the issues of public health. They will gain a deeper understanding about the health news they hear, the web sites they visit, and the research they read.
Reprint of a reference book first published in 1987. Lavishly illustrated, it contains detailed descriptions of all the important weeds of Australia. Suitable for primary producers, students, agricultural advisers and research workers.
The reference JAMA called "an outstanding contribution" and "must reading" is back in a fully revised New Edition! This 2-volume set presents cutting-edge discussions of scientific principles, pathogenesis, pathophys-iology, diagnosis, treatment, and prevention for the full range of tropical infectious diseases. A new bonus CD-ROM, a clinical-focused organization, standardized life-cycle diagrams, and 850 illustrations make vital guidance easy to find and apply
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease.
Fetal and Neonatal Physiology, edited by Drs. Polin, Fox, and Abman, focuses on physiologic developments of the fetus and newborn and their impact on the clinical practice of neonatology. A must for practice, this 4th edition brings you the latest information on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. You'll also have easy access to the complete contents and illustrations online at expertconsult.com. Gain a comprehensive, state-of-the-art understanding of normal and abnormal physiology, and its relationship to disease in the fetus and newborn premature infant, from Dr. Richard Polin and other acknowledged worldwide leaders in the field. Understand the implications of fetal and neonatal physiology through chapters devoted to clinical correlation. Apply the latest insights on genetic therapy, intrauterine infections, brain protection and neuroimaging, and much more. Effectively manage the consequences of intrauterine infections with three new chapters covering intrauterine infection and preterm birth, intrauterine infection and brain injury, and intrauterine infection and chronic lung disease. Access the complete contents and illustrations online at expertconsult.com - fully searchable! Get the latest developments and a full understanding of the distinct physiology of the fetus and newborn so you can treat and manage sick newborns and preemies.
Rated by an independent panel as the best introductory Global Health text for undergraduates, Global Health 101, Third Edition is a clear, concise, and user-friendly introduction to the most critical issues in global health. It illustrates key themes with an extensive set of case studies, examples, and the latest evidence. Particular attention is given to the health-development link, to developing countries, and to the health needs of poor and disadvantaged people. The Third Edition is a thorough revision that offers an extensive amount of new and updated information, while maintaining clarity, simplicity, and ease of use for faculty and students. Offering the latest data on the burden of disease, the book presents unique content on key topics that are often insufficiently covered in introductory materials, such as immunization and adolescent health.
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