Richard Losick's Books

The Hierarchical Genome and Differentiation Waves

Novel Unification of Development, Genetics and Evolution

By: Richard Gordon

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The Hierarchical Genome and Differentiation Waves

Novel Unification of Development, Genetics and Evolution

By: Richard Gordon

Over the past few decades numerous scientists have called for a unification of the fields of embryo development, genetics, and evolution. Each field has glaring holes in its ability to explain the fundamental phenomena of life. In this book, the author shows how the phenomenon of cell differentiation, considered in its temporal and spatial aspects during embryogenesis, provides a starting point for a unified theory of multicellular organisms (plants, fungi and animals), including their evolution and genetics. This unification is based on the recent discovery of differentiation waves by the author and his colleagues, described in the appendices, and illustrated by a flip movie prepared by a medical artist. To help the reader through the many fields covered, a glossary is included.This book will be of great value to the researcher and practicing doctors/scientists alike. The research students will receive an in-depth tutorial on the topics covered. The seasoned researcher will appreciate the applications and the gold mine of other possibilities for novel research topics.

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Page Count

936

Publisher

World Scientific

Published Date

ISBN 10

9810222688

ISBN 13

9789810222680

Biochemistry Student Companion

By: Jeremy M. Berg,Frank H. Deis,Nancy Counts Gerber,Richard Gumport,Roger E. Koeppe

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Biochemistry Student Companion

By: Jeremy M. Berg,Frank H. Deis,Nancy Counts Gerber,Richard Gumport,Roger E. Koeppe

Since its first edition in 1975, this extraordinary textbook has helped shape the way biochemistry is taught, offering exceptionally clear writing, innovative graphics, coverage of the latest research techniques and advances, and a signature emphasis on physiological and medical relevance. Those defining features are at the heart of this edition.

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Page Count

1224

Publisher

Macmillan

Published Date

ISBN 10

1429231157

ISBN 13

9781429231152

The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman

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The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and includes chapter problems and other elements that make the book more useful for course instruction. - New edition includes new chapter problems and exercises to help students learn, plus extensive references and illustrations - Clearly presents an organic chemist's perspective of how drugs are designed and function, incorporating the extensive changes in the drug industry over the past ten years - Well-respected author has published over 200 articles, earned 21 patents, and invented a drug that is under consideration for commercialization

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Page Count

650

Publisher

Elsevier

Published Date

ISBN 10

0080513379

ISBN 13

9780080513379

The Organic Chemistry of Drug Design and Drug Action, Power PDF

By: Richard B. Silverman

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The Organic Chemistry of Drug Design and Drug Action, Power PDF

By: Richard B. Silverman

This CD-ROM edition of Silverman's Organic Chemisry of Drug Design and Drug Action, Second Edition reflects the significant changes in the drug industry in recent years, using an accessible interactive approach. This CD-ROM integrates the author's own PowerPoint slides, indexed and linked to the book pages in PDF format. The three-part structure includes an all-electronic text with full-text search capabilites and nearly 800 powerpoint slides. This is a unique and powerful combination of electronic study guide and full book pages. Users can hyperlink seamlessly from the main text to key points and figures on the outline and back again. It serves as a wonderful supplement for instructors as well as a fully integrated text and study aid for students. * Three-part package includes 1) powerpoint, 2) integrated powerpoint and pdf-based text, and 3) fully searchable PDF-based text with index * Includes new full-color illustrations, structures, schemes, and figures as well as extensive chapter problems and exercises * User-friendly buttons transition from overview (study-guide) format to corresponding book page and back with the click of a mouse * Full-text search capabality an incomparable tool for researchers seeking specific references and/or unindexed phrases

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Page Count

634

Publisher

Elsevier

Published Date

ISBN 10

0080575382

ISBN 13

9780080575384

Advanced Molecular Biology

A Concise Reference

By: Richard Twyman

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Advanced Molecular Biology

A Concise Reference

By: Richard Twyman

Advanced Molecular Biology emphasises the unifying principles and mechanisms of molecular biology, with frequent use of tables and boxes to summarise experimental data and gene and protein functions. Extensive cross-referencing between chapters is used to reinforce and broaden the understanding of core concepts. This is the ideal source of comprehensive, authoritative and up-to-date information for all those whose work is in the field of molecular biology. This book emphasises the unifying principles and mechanisms of molecular biology, with frequent use of tables and boxes to summarise experimental data and gene and protein functions.

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Page Count

763

Publisher

Garland Science

Published Date

ISBN 10

1135324468

ISBN 13

9781135324469

Divine Action and Natural Selection

Science, Faith and Evolution

By: Joseph Seckbach,Richard Gordon

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Divine Action and Natural Selection

Science, Faith and Evolution

By: Joseph Seckbach,Richard Gordon

The debate between divine action, or faith, and natural selection, or science, is garnering tremendous interest. This book ventures well beyond the usual, contrasting American Protestant and atheistic points of view, and also includes the perspectives of Jews, Muslims, and Roman Catholics. It contains arguments from the various proponents of intelligent design, creationism, and Darwinism, and also covers the sensitive issue of how to incorporate evolution into the secondary school biology curriculum. Comprising contributions from prominent, award-winning authors, the book also contains dialogs following each chapter to provide extra stimulus to the readers and a full picture of this ?hot? topic, which delves into the fundamentals of science and religion.

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Page Count

1122

Publisher

World Scientific

Published Date

ISBN 10

9812834338

ISBN 13

9789812834331

Embryogenesis Explained

By: Natalie K Gordon,Richard Gordon

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Embryogenesis Explained

By: Natalie K Gordon,Richard Gordon

The greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time.As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.

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Page Count

784

Publisher

World Scientific

Published Date

ISBN 10

9814740691

ISBN 13

9789814740692

Biobased Surfactants

Synthesis, Properties, and Applications

By: Douglas G. Hayes,Daniel K. Solaiman,Richard D. Ashby

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Biobased Surfactants

Synthesis, Properties, and Applications

By: Douglas G. Hayes,Daniel K. Solaiman,Richard D. Ashby

Biobased Surfactants: Synthesis, Properties, and Applications, Second Edition, covers biosurfactant synthesis and applications and demonstrates how to reduce manufacturing and purification costs, impurities, and by-products. Fully updated, this book covers surfactants in biomedical applications, detergents, personal care, food, pharmaceuticals, cosmetics, and nanotechnology. It reflects on the latest developments in biobased surfactant science and provides case scenarios to guide readers in efficient and effective biobased surfactant application, along with strategies for research into new applications. This book is written from a biorefinery-based perspective by an international team of experts and acts as a key text for researchers and practitioners involved in the synthesis, utilization, and development of biobased surfactants. - Describes new and emerging biobased surfactants and their synthesis and development - Showcases an interdisciplinary approach to the topic, featuring applications to chemistry, biotechnology, biomedicine, and other areas - Presents the entire lifecycle of biobased surfactants in detail

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Page Count

544

Publisher

Elsevier

Published Date

ISBN 10

0128127066

ISBN 13

9780128127063

Dictyostelium

Evolution, Cell Biology, and the Development of Multicellularity

By: Richard H. Kessin

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Dictyostelium

Evolution, Cell Biology, and the Development of Multicellularity

By: Richard H. Kessin

Dictyostelia are soil amoebae capable of extraordinary feats of survival, motility, chemotaxis, and development. Characterised by their ability to transform from a single-celled organism into an elaborate assemblage of thousands of synchronously-moving cells, Dictyostelids are often referred to as 'social amoebae', and have been the subjects of serious study since the 1930s. Research in this area has been instrumental in understanding many problems in cellular biology. Beginning with the history of Dictyostelids and discussing each stage of their development, this book considers the evolution of this unique organism, analyses the special properties of the Dictyostelid genome, and presents in detail the methods available, at the time of the book's original publication in 2001, to manipulate their genes. Representing the synthesis of such material and with an emphasis on combining classical experiments with modern molecular findings, this book will be essential for researchers and graduates in developmental and cellular biology.

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Page Count

318

Publisher

Cambridge University Press

Published Date

ISBN 10

0521583640

ISBN 13

9780521583640

The Harvey Lectures |

By: Ronald M. Evans,Christine Guthrie,Leland H. Hartwell,Arnold J. Levine,Richard Losick,Randy W. Schekman,Robert Tjian

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The Harvey Lectures |

By: Ronald M. Evans,Christine Guthrie,Leland H. Hartwell,Arnold J. Levine,Richard Losick,Randy W. Schekman,Robert Tjian

This is the latest volume in the distinguished Harvey Lectures Series, which provides a topical overview of recent trends in biomedical research.

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Page Count

168

Publisher

Wiley-Liss

Published Date

ISBN 10

0471146226

ISBN 13

9780471146223

Book's by Richard Losick

The Hierarchical Genome and Differentiation Waves

The Hierarchical Genome and Differentiation Waves

Biochemistry Student Companion

Biochemistry Student Companion

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action, Power PDF

The Organic Chemistry of Drug Design and Drug Action, Power PDF

Advanced Molecular Biology

Advanced Molecular Biology

Divine Action and Natural Selection

Divine Action and Natural Selection

Embryogenesis Explained

Embryogenesis Explained

Biobased Surfactants

Biobased Surfactants

Dictyostelium

Dictyostelium

The Harvey Lectures |

The Harvey Lectures |

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