A proposal for moving from price-centric to innovation-centric competition policy, reviewing theory and evidence on economic incentives for innovation. Competition policy and antitrust enforcement have traditionally focused on prices rather than innovation. Economic theory shows the ways that price competition benefits consumers, and courts, antitrust agencies, and economists have developed tools for the quantitative evaluation of price impacts. Antitrust law does not preclude interventions to encourage innovation, but over time the interpretation of the laws has raised obstacles to enforcement policies for innovation. In this book, economist Richard Gilbert proposes a shift from price-centric to innovation-centric competition policy. Antitrust enforcement should be concerned with protecting incentives for innovation and preserving opportunities for dynamic, rather than static, competition. In a high-technology economy, Gilbert argues, innovation matters. Gilbert considers both theory and available empirical evidence on the relationships among market structure, firm behavior, and the production of new products and services. He reviews the distinctive features of the high-tech economy and why current analytical tools used by antitrust enforcers aren't up to the task of assessing innovation concerns. He considers, from the perspective of innovation competition, Kenneth Arrow's “replacement effect” and the Schumpeterian theory of market power and appropriation; discusses the effect of mergers on innovation and future price competition; and reviews the empirical literature on competition, mergers, and innovation. He describes examples of merger enforcement by US and European antitrust agencies; examines cases brought against Microsoft and Google; and discusses the risks and benefits of interoperability standards. Finally, he offers recommendations for competition policy. The open access edition of this book was made possible by generous funding from Arcadia – a charitable fund of Lisbet Rausing and Peter Baldwin.
Hawaii has been referred to as the crossroads of the Pacific. This book illustrates how many world cultures and customs meet in the Hawaiian Islands, providing a chronological overview highlighted by extracts from important works that express Hawaii's unique history. This work starts with chronological chapters on general and ancient Hawaiian history and continues through early Western contact, the 19th century, and Hawaii's annexation to the United States. Topics include politics, religion, social issues, business, ethnic groups, and race relations.
An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Bringing together contributions by leading international experts, Drug Delivery covers the entire field in a systematic but concise way. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination-including overviews, timely examples, and extensive references-of a host of specific subjects, including: * Receptor-mediated drug delivery * Prodrug delivery approaches * Oral protein and peptide drug delivery * Gene therapy and gene delivery * Ultrasound-mediated drug delivery * Polycationic peptides and proteins in drug delivery * Pulmonary drug delivery * Antibody-directed drug delivery * Efflux transporters in drug excretion * Intellectual property issues in drug delivery
While research has enabled us to better understand the nonhuman primates, they have repaid that by repaid that by providing medical scientists with important tools for the study of human biomedical problems. This book is about those research tools. The book was designed by identifying areas of human medical research that are under intensive research study today. Authors were then selected based on their expertise at using nonhuman primates as models for the human condition. Each was asked to use as comparative an approach as models for the human condition. Each was asked to use a comparative an approach as possible, to provide the reader with knowledge relating to the usefulness of various nonhuman primate species to each specific research area.
A proposal for moving from price-centric to innovation-centric competition policy, reviewing theory and evidence on economic incentives for innovation. Competition policy and antitrust enforcement have traditionally focused on prices rather than innovation. Economic theory shows the ways that price competition benefits consumers, and courts, antitrust agencies, and economists have developed tools for the quantitative evaluation of price impacts. Antitrust law does not preclude interventions to encourage innovation, but over time the interpretation of the laws has raised obstacles to enforcement policies for innovation. In this book, economist Richard Gilbert proposes a shift from price-centric to innovation-centric competition policy. Antitrust enforcement should be concerned with protecting incentives for innovation and preserving opportunities for dynamic, rather than static, competition. In a high-technology economy, Gilbert argues, innovation matters. Gilbert considers both theory and available empirical evidence on the relationships among market structure, firm behavior, and the production of new products and services. He reviews the distinctive features of the high-tech economy and why current analytical tools used by antitrust enforcers aren't up to the task of assessing innovation concerns. He considers, from the perspective of innovation competition, Kenneth Arrow's “replacement effect” and the Schumpeterian theory of market power and appropriation; discusses the effect of mergers on innovation and future price competition; and reviews the empirical literature on competition, mergers, and innovation. He describes examples of merger enforcement by US and European antitrust agencies; examines cases brought against Microsoft and Google; and discusses the risks and benefits of interoperability standards. Finally, he offers recommendations for competition policy. The open access edition of this book was made possible by generous funding from Arcadia – a charitable fund of Lisbet Rausing and Peter Baldwin.
Provides an account, from the point of view of the U.S. Army forces employed, of the 1990-91 Persian Gulf War, from the Iraqi invasion of Kuwait to the withdrawal of coalition forces from southeastern Iraq. It focuses on the Army's part in this war, particularly the activities of the Headquarters, Third Army, and the Army Forces Central Command (ARCENT). It looks especially at the activities of the VII Corps, which executed ARCENT's main effort in the theater ground force schwerpunkt -- General Schwarzkopf's "Great Wheel." This is not an official history; the author speaks in his own voice and makes his own judgments. Maps.
Love is one of the most exhilarating emotions we experience--unfortunately, it is also one of the most painful and sometimes traumatic. The unresolved emotional scars from a broken heart can manifest as a "love trauma syndrome." Until now, a love trauma was thought to precipitate other common psychiatric conditions, such as depression or adjustment disorders, but these generic psychiatric ailments are not adequate for articulating the full and unique character of the condition following love trauma. The Love Trauma Syndrome: Free Yourself from the Pain of a Broken Heart fills the need of patients feeling isolated, ashamed, or alone in their anguish. Dr. Richard Rosse, a psychiatrist with expertise in the area of emotional breakdown, provides a concrete path to help people understand this condition. At times, the syndrome can seriously diminish the sufferer's quality of life, and dramatically impair social, academic, and occupational activities. Dr. Rosse warns that there can also be bouts of severe manifestations, things go horribly wrong. Patients may end up committing suicide. A few become so obsessed by their lost loves that they are driven to stalk, attack, or murder these persons and then ultimately commit suicide. However, most patients suffer alone and in silence without ever resorting to an act of physical violence.Dr. Rosse clearly explains that Love Trauma Syndrome is a clinical disorder of "too much memory" in which the past intrudes upon the present to influence thoughts, feelings, and behaviors to a much greater extent than is expected. It can also be associated with a variety of other behavioral problems: the avoidance of future loving relationships, nervousness, feeling "unreal" or out of place, anger, and sleep disturbances. The book will educate mental health clinicians on how to recognize and treat people with the syndrome, and Dr. Rosse discusses a variety of psychotherapeutic and pharmacological treatment options and their rationale.The Love Trauma Syndrome is the first book to describe the condition and to present a full array of self-help strategies and specific techniques tailored to help those suffering from a love trauma. Designed for both lay and professional audiences, it is the ideal resource for anyone--male or female, young or old, gay or straight--hurt by love to understand what to do to escape the bleak prison of misery.
In the exciting and growing field of hospital medicine, you're as concerned with the efficient management of your unit as you are the effective care of your patients. This title is your ideal new clinical reference on both counts. Nationally recognized experts equip you with practical, actionable guidance on all of the challenges you face every day—making it easier for you to provide optimal care for every patient. State-of-the-art, evidence-based, hospital-focused guidelines on clinical assessment, diagnosis, prognosis, treatment, and discharge/follow-up planning help you to effectively manage all of the key disorders in every body system. 20 chapters focused on peri-operative care assist you in navigating this increasingly important component of hospital medicine practice. Expert advice on systems issues explores how to establish and enhance a hospitalist program, provide leadership, manage patient transitions of care, establish a teamwork model with hospital staff, promote patient safety and staff performance improvement, standardize care, and navigate legal and ethical concerns.
Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression — A Selection of Readings for Health Services Providers presents an edited and annotated collection of recent medical journal publications and abstracts illustrating new approaches to treatment derived from the metabolic theory of cancer. It intends to shed an early light on a relatively new approach to our understanding of the cancer cell idiosyncratic metabolic dysfunction, and on evidence-based new treatment strategies derived from that understanding. The book discusses topics such as tumor starvation by L-arginine deprivation; L-canavanine depriving tumors of L-arginine in pancreatic, multiple myeloma and breast cancer; glucose deprivation and intermittent fasting; glutamine uptake in cancer; the relation of oxygen-starved cancer cells with aspartate; and reducing tolerance of tumor cells to nutrition starvation. The content is presented in a contextualized and practical way in order to facilitate the transition from bench to bedside. This is a valuable resource for practitioners, oncologists and other members of healthcare chain who are interested in learning more about the most recent tumor cell starvation strategies and how they can improve overall treatment outcome. Provides extensive comments on scientific publications detailing recent findings about tumor cell auxotrophy applied to tumor cell starvation strategies Helps the reader to find relevant and practical information on cancer cell starvation, otherwise spread through niched specialized journals, in one single place Comments on the recent findings putting them in context of clinical practice in order to provide the reader with means of translating high level research to the clinics
Provides personality profiles, historical essays, and first-person reminiscences of the history of the University of Texas. Topics include recurring attacks on the school by politicians and regents, the institution's history of segregation and struggles to become a diverse university, the sixties' protest movements, and the Tower sniper shooting.
If you are not already in a management position, chances are you soon will be. According to the Bureau of Statistics, the fastest growing areas of employment for engineers are in engineering/science management. With over 200 contributing authors, The Technology Management Handbook informs and assists the more than 1.5 million engineering managers in the practice of technical management. Written from the technical manager's perspective and written for technologists who are managers, The Technology Management Handbook presents in-depth information on the science and practice of management. Its comprehensive coverage encompasses the field of technology management, offering information on: Entrepreneurship Innovations Economics Marketing Product Development Manufacturing Finance Accounting Project Management Human Resources International Business
To study this transition from universalism to cultural particularism, Richard King focuses on the arguments of major thinkers, movements, and traditions of thought, attempting to construct a map of the ideological positions that were staked out and an intellectual history of this transition.
Quantum computing explained in terms of elementary linear algebra, emphasizing computation and algorithms and requiring no background in physics. This introduction to quantum algorithms is concise but comprehensive, covering many key algorithms. It is mathematically rigorous but requires minimal background and assumes no knowledge of quantum theory or quantum mechanics. The book explains quantum computation in terms of elementary linear algebra; it assumes the reader will have some familiarity with vectors, matrices, and their basic properties, but offers a review of the relevant material from linear algebra. By emphasizing computation and algorithms rather than physics, it makes quantum algorithms accessible to students and researchers in computer science who have not taken courses in quantum physics or delved into fine details of quantum effects, apparatus, circuits, or theory.
Decentralization has become a popular management strategy in many European health care systems. The term describes a wide variety of power transfer arrangements and accountability systems. The logic of decentralization is grounded in an intrinsically powerful idea; that smaller organizations, properly structured and steered, are inherently more agile and accountable than larger organizations. In a world where large organizations control wide swathes of both public and private sector activity, the possibility of establishing more locally operated, locally responsible institutions holds out great attraction. This text explores the capacity and impact of decentralization within European health care systems. It examines both the theoretical underpinnings as well as recent practical experiences, drawing upon both published literature and evidence collected directly from the field. The book also assesses the appropriateness of management processes within health systems for implementing a successful decentralization strategy. Decentralization in Health Care will appeal to health policy makers, postgraduates taking courses in health services management, HR, health policy and health economics, and human resource professionals.
Covering both surgical and non-surgical pain, Acute Pain Management Essentials is a comprehensive, clinically oriented reference for the entire acute pain management team. Edited by Drs. Alan David Kaye and Richard D. Urman, this new title brings together the expertise of contributing authors from anesthesiology, medicine, surgery, and allied health professions to offer an interdisciplinary approach to this complex and fast-changing field. Beginning with an overview of basic principles, it then approaches pain management by organ system, by patient population, and by treatment modality, ending with review of subspecialty considerations and related topics.
The use of the wind as an energy source is increasing and growing worldwide. Wind energy is an important non-fossil option to supplement fossil (coal, natural gas and oil) and nuclear fuels for the generation of electricity. Many parts of the world, particularly the coastlines of Western Europe, North Africa, North and South America, India, Eastern Russia, China, the Philippines, Australia and New Zealand, experience a high annual incidence of wind energy. The United Kingdom of Great Britain and Northern Ireland, together with the Republic of Ireland form a particularly windy location, being favoured with strong westerly winds. The technology of the design and installation of wind turbines and wind farms are, in fact, well established. Operational practice, though, is still being developed as engineers learn by experience. This book is written for electrical engineers concerned with the use of wind power for generating electricity. It incorporates some meteorological features of international wind supply plus a survey of the past and present wind turbines with technical assessment of the choice of turbine sites. Detailed coverage is given to the different types of electrical generator machines used and the electronic control devices employed in modern turbine systems. Importantly, this book devotes full chapters to the integration of wind farms into established electrical grid supply systems, and the environmental and economic aspects of wind generation. Engineers will be drawn to the practical approach in this book, featuring worked numerical examples — complete with answers — at the end of some chapters.
This volume constitutes the post-proceedings of the 2005 Computer Music Modeling and Retrieval Symposium (CMMR2005). This event took place during September 26–28, 2005 at the Institute of Information Science and Technologies (ISTI), Italian National Research Council (CNR), Pisa, Italy.
This edition retains the case history approach to emphasize the subsurface diagnosis of environments using seismic and geophysical well logs and their application to petroleum exploration and production. This book should be of interest to undergraduates in sedimentology and petroleum geology.
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