When firefighter John Casey heroically saves an elderly woman named Mrs. Parker in a terrible fire, he has no idea that this one act will change his life forever. A mysterious letter arrives from Mrs. Parkers attorney, summoning John and his wife, Susan, to a meeting. The couple receives news they never expected. They are the sole beneficiaries of Mrs. Parkers incredible fortune, worth an estimated two billion dollars; they now own homes in Palm Beach, Boston, and New York. With all this money comes a new challenge. As Christians, John and Susan know they need to be responsible stewards; accordingly, they give to their church and to other charities. Yet as soon as they travel to Florida to look at their new property, strange things begin to happen. Unsavory men begin following them and, unbeknownst to the couple, their own servants are involved in monitoring their every move. As John and Susan, along with their best friends, Mark and Carol, begin to dig deeper into the Parker family history, they discover a sordid tale full of deceit, murder, demons, and angels. John and Susan must adorn the armor of God if they are to prevail over Satans minions and emerge with their faithand their livesintact.
An indispensable tool for those working at the front lines of new drug development Written for busy professionals at the forefront of new drug development, Drug Delivery gets readers quickly up to speed on both the principles and latest applications in the increasingly important field of drug delivery. Recent developments in such areas as combinatorial chemistry, proteomics, and genomics have revolutionized researchers' ability to rapidly identify and synthesize new pharmacological compounds. However, delivery-related properties remain a significant reason for clinical trial failures. Bringing together contributions by leading international experts, Drug Delivery covers the entire field in a systematic but concise way. It begins with an in-depth review of key fundamentals, such as physiochemical and biological barriers; drug delivery pathways; metabolism; drug formulation; pharmacokinetic and pharmacodynamic issues; and more. The remainder of the book is devoted to the systematic examination-including overviews, timely examples, and extensive references-of a host of specific subjects, including: * Receptor-mediated drug delivery * Prodrug delivery approaches * Oral protein and peptide drug delivery * Gene therapy and gene delivery * Ultrasound-mediated drug delivery * Polycationic peptides and proteins in drug delivery * Pulmonary drug delivery * Antibody-directed drug delivery * Efflux transporters in drug excretion * Intellectual property issues in drug delivery
The first book to address the fundamental nexus that binds poverty and income inequality to soaring health care utilization and spending, Poverty and the Myths of Health Care Reform is a must-read for medical professionals, public health scholars, politicians, and anyone concerned with the heavy burden of inequality on the health of Americans.
Why have Blacks won political empowerment in some cities and in others remained subordinated or had their achievements rolled back? Why do some cities have many Black leaders with multi-racial appeal while other cities have none? Subordination or Empowerment answers these questions through detailed historical examinations of the Black struggle for political power in Chicago, Gary, Philadelphia, and Atlanta. Keiser argues that electoral competition among White factions has created opportunities for Black leaders to win genuine political empowerment and avoid subordination. When electoral competition among Whites does not exist, Black votes lose their electoral leverage, leading to the rise of extra-electoral strategies. Keiser's dynamic theory of leadership formation explains the current appeal of Black separatism and messianism at the local and national levels and the consequent rise of leaders such as Louis Farakhan, and offers a rejoinder to Cornel West's critique of Black leadership in Race Matters.
Since 1975, Dr. Kenneth Swaiman's classic text has been the reference of choice for authoritative guidance in pediatric neurology, and the 6th Edition continues this tradition of excellence with thorough revisions that bring you fully up to date with all that's new in the field. Five new sections, 62 new chapters, 4 new editors, and a reconfigured format make this a comprehensive and clearly-written resource for the experienced clinician as well as the physician-in-training. - Nearly 3,000 line drawings, photographs, tables, and boxes highlight the text, clarify key concepts, and make it easy to find information quickly.
As many as 80% of patients will suffer from back pain at some point in their lifetime. It is the most common form of disability, and the second largest cause of work absenteeism. An early, proactive management approach offers the best route to minimizing these conditions. Renowned authority Curtis W. Slipman, MD and a team of multidisciplinary authorities present you with expert guidance on today's best non-surgical management methods, equipping you with the knowledge you need to offer your patients optimal pain relief. Refresh your knowledge of the basic principles that must be understood before patients with spinal pain can be properly treated. Know what to do when first-line tests and therapies fail, using practice-proven diagnostic and therapeutic algorithms. Offer your patients a full range of non-surgical treatment options, including pharmacology, physical therapy, injection techniques, ablative procedures, and percutaneous disc decompression. Make an informed surgical referral with guidance on indications, contraindications, methods, and postoperative rehabilitation. Better understand key techniques and procedures with visual guidance from more than 500 detailed illustrations.
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