Winner of the 2021 California Book Award (Californiana category) A brilliant California history, in word and image, from an award-winning historian and a documentary photographer. “This is the West, sir. When the legend becomes fact, print the legend.” This indelible quote from The Man Who Shot Liberty Valance applies especially well to California, where legend has so thoroughly become fact that it is visible in everyday landscapes. Our foremost historian of the West, Richard White, never content to “print the legend,” collaborates here with his son, a talented photographer, in excavating the layers of legend built into California’s landscapes. Together they expose the bedrock of the past, and the history they uncover is astonishing. Jesse White’s evocative photographs illustrate the sites of Richard’s historical investigations. A vista of Drakes Estero conjures the darkly amusing story of the Drake Navigators Guild and its dubious efforts to establish an Anglo-Saxon heritage for California. The restored Spanish missions of Los Angeles frame another origin story in which California’s native inhabitants, civilized through contact with friars, gift their territories to white settlers. But the history is not so placid. A quiet riverside park in the Tulare Lake Basin belies scenes of horror from when settlers in the 1850s transformed native homelands into American property. Near the lake bed stands a small marker commemorating the Mussel Slough massacre, the culmination of a violent struggle over land titles between local farmers and the Southern Pacific Railroad in the 1870s. Tulare is today a fertile agricultural county, but its population is poor and unhealthy. The California Dream lives elsewhere. The lake itself disappeared when tributary rivers were rerouted to deliver government-subsidized water to big agriculture and cities. But climate change ensures that it will be back—the only question is when.
Cryopreserved allograft tissues are now standard materials for the reconstructive cardiac surgeon. Since publication of the first edition ("Cardiac Reconstructions with Allograft Valves") in 1989, the field has progressed dramatically with increased clinical use of cardiovascular allograft tissues, with the development of new surgical techniques, and with advances in the understanding of the fundamentals of valve transplantation biology and cryopreservation. As a result, over two-thirds of the present volume represents new material. Fifty-six authors bring their expertise to thirteen comprehensive, lavishly illustrated sections which discuss the principles of the use of homograft valves, major clinical series of homograft valves for both left and right ventricular outflow tracts, cryopreserved allograft tissue for cardiac reconstruction, cell biology of heart valve leaflets, cryobiology of heart valve preservation, morphological, biochemical, and explant pathology studies of allograft heart valves, allograft valve banking, as well as detailed explanation of surgical techniques for valve and root methods for left and right ventricular outflow tract reconstructions, the Ross operation and variants, and complex reconstructions. A final section presents potential future directions for the field. Over 400 illustrations, created expressly for this book, depict the surgical techniques from the perspective of the surgeon standing at the operating table. All surgeons performing pediatric and/or adult valve replacements and reconstructive cardiac surgeries will benefit from the described methods. Cardiothoracic residents and cardiologists will also find the text useful. It will provide the surgeon with an enhanced understanding of the biological and material properties of allografts and increased familiarity with the range of surgical techniques applicable for the use of these valves, particularly in the successful management of challenging cardiac reconstructions.>
From the contents: · C. Brater and M. D. Murray: The effects of NSAIDs on the kidney · G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs · M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms · S.P. Gupta: Studies on cardiovascular drugs · G. Polak: Antifungal chemotherapy: An everlasting battle · O. Valdenaire: New insights into the bioamine receptor family.
In the first full-length study in English of Carlo Collodi's The Adventures of Pinocchio, the authors show how the checkered history of the puppet illuminates social change from the pre World War One era to the present. The authors argue that most Americans know a trivialized, diluted version of the tale, one such source is Disney's perennial classic. The authors also discover that when adults are introduced to the 'real' story, they often deem it as unsuitable for children. Placing the puppet in a variety of contexts, the authors chart the progression of this childhood tale that has frequently undergone dramatic revisions to suit America's idea of children's literature.
Effectively perform today’s most state-of-the-art neurosurgical procedures with Youmans Neurological Surgery, 6th Edition, edited by H. Richard Winn, MD. Still the cornerstone of unquestioned guidance on surgery of the nervous system, the new edition updates you on the most exciting developments in this ever-changing field. In print and online, it provides all the cutting-edge details you need to know about functional and restorative neurosurgery (FRN)/deep brain stimulation (DBS), stem cell biology, radiological and nuclear imaging, neuro-oncology, and much more. And with nearly 100 intraoperative videos online at www.expertconsult.com, as well as thousands of full-color illustrations, this comprehensive, multimedia, 4-volume set remains the clinical neurosurgery reference you need to manage and avoid complications, overcome challenges, and maximize patient outcomes. Overcome any clinical challenge with this comprehensive and up-to-date neurosurgical reference, and ensure the best outcomes for your patients. Rely on this single source for convenient access to the definitive answers you need in your practice. Successfully perform functional and restorative neurosurgery (FRN) with expert guidance on the diagnostic aspects, medical therapy, and cutting-edge approaches shown effective in the treatment of tremor, Parkinson’s disease, dystonia, and psychiatric disorders. Sharpen your neurosurgical expertise with updated and enhanced coverage of complication avoidance and intracranial pressure monitoring, epilepsy, neuro-oncology, pain, peripheral nerve surgery, radiosurgery/radiation therapy, and much more. Master new techniques with nearly 100 surgical videos online of intraoperative procedures including endoscopic techniques for spine and peripheral nerve surgery, the surgical resection for spinal cord hemangiomas, the resection of a giant AVM; and the radiosurgical and interventional therapy for vascular lesions and tumors. Confidently perform surgical techniques with access to full-color anatomic and surgical line drawings in this totally revised illustration program. Get fresh perspectives from new section editors and authors who are all respected international authorities in their respective neurosurgery specialties. Conveniently search the complete text online, view all of the videos, follow links to PubMed, and download all images at www.expertconsult.com.
The book includes new material, in particular examples of 3-D models and techniques for using kinematic models to predict fault and ramp-anticline geometry. The book is geared toward the professional user concerned about the accuracy of an interpretation and the speed with which it can be obtained from incomplete data. Numerous analytical solutions are given that can be easily implemented with a pocket calculator or a spreadsheet.
Globally, the methodologies of legal education have not changed in any fundamental way, some methods dating back hundreds of years. Law schools have relied, for too long, on passive learning methods such as lectures or cases. Clinical legal education provides an alternative that is more than just another pedagogical method. It provides a way for students to experience their emerging professional selves, while providing services or projects with poor and underrepresented clients. This book documents both the historical origins of clinical experiments in the earliest days of US university legal education, and the now-global reach of clinical pedagogy as a proven tool for effective training of legal professionals.
The California Constitution is one of the longest in the world and has been revised over 500 times since its original drafting in 1849. In its current incarnation, the constitution reflects the state's mistrust of elected officials, gives cities and towns broad home rule powers, and outlines governance for the state's university system. The California State Constitution provides an outstanding constitutional and historical account of the state's basic governing charter. In addition to an overview of California's constitutional history, it offers an in-depth, section-by-section analysis of the entire constitution, detailing the many significant changes that have been made since its initial drafting in 1849. This treatment, along with a table of cases, index, and the bibliography provides an unsurpassed reference guide for students, scholars, and practitioners of California's constitution. Previously published by Greenwood, this title has been brought back in to circulation by Oxford University Press with new verve. Re-printed with standardization of content organization in order to facilitate research across the series, this title, as with all titles in the series, is set to join the dynamic revision cycle of The Oxford Commentaries on the State Constitutions of the United States. The Oxford Commentaries on the State Constitutions of the United States is an important series that reflects a renewed international interest in constitutional history and provides expert insight into each of the 50 state constitutions. Each volume in this innovative series contains a historical overview of the state's constitutional development, a section-by-section analysis of its current constitution, and a comprehensive guide to further research. Under the expert editorship of Professor G. Alan Tarr, Director of the Center on State Constitutional Studies at Rutgers University, this series provides essential reference tools for understanding state constitutional law. Books in the series can be purchased individually or as part of a complete set, giving readers unmatched access to these important political documents.
Longstreth explores the early development of two kinds of retail space that have become ubiquitous in the United States in the second half of the twentieth century. Richard Longstreth is one of the few historians to focus on ordinary commercial buildings—buildings usually associated with commercial builders and real estate developers rather than architects and thus generally overlooked by historians of "high" architecture. Here Longstreth explores the early development of two kinds of retail space that have become ubiquitous in the United States in the second half of the twentieth century. One, external, is devoted to the circulation and parking of automobiles on retail premises. Longstreth analyzes the origins of this development in the 1910s and 1920s, with the super service station and then the drive-in market. The other type of space, internal, was introduced soon thereafter with the single-story supermarket. The most innovative aspect of the supermarket was how its interior was designed for high-volume turnover of a large selection of goods with a minimum of staff assistance. Longstreth focuses on Los Angeles, the principal center for the development of both kinds of space, during the period from the mid-1910s to the early 1940s. This richly illustrated study integrates architectural, cultural, economic, and urban factors to describe the evolution of retailing and how it has affected the urban landscape.
Over the past several decades, Richard Ellis has produced a remarkable body of work that has been called "magnificent" (Washington Post Book World), "masterful" (Scientific American), "magical" (Men's Journal), and a "dazzling tour de force" (Christian Science Monitor). Ellis's new book-a fascinating tour through the world of the sperm whale-will surely inspire more such praise for the author heralded by Publisher Weekly as "America's foremost writer on marine research." Written with Ellis's deep knowledge and trademark passion, verve, and wit-and illustrated with a wide array of images including his own signature artwork-his study covers the full spectrum of the sperm whale's existence from its prehistoric past to its current endangered existence. Ellis, as no one else can, illuminates the iconic impact of Physeter macrocephalus ("big-headed blower") on our history, environment, and culture, with a substantial nod to Herman Melville and Moby-Dick, the great novel that put the sperm whale (and whaling) on the literary map. Ranging far and wide, Ellis covers the sperm whale's evolution, ecology, biology, anatomy, behavior, social organization, intelligence, communications, migrations, diet, and breeding. He also devotes considerable space to the whale's hunting prowess, including its clashes with the giant squid, and to the history of the whaling industry that decimated its numbers during the last two centuries. He even includes a story about a beached juvenile he helped rescue, an event that provided scientists with one of their first opportunities to observe a sperm whale in the water and up close. Offering a rich tapestry for anyone with an interest in the marvels of ocean life, Ellis's book provides an indispensable guide to the life and times of one of the planet's most intelligent, elusive, and endangered species.
The 19th Hole examines the design of many of the world's great golf clubhouses. It's part of the IMAGES series of titles that looks exclusively at world-best practice in architecture. The book is a photographic feast of the often-sumptuous clubhouse fit-outs that accompanies golfing at these illustrious courses. This book is endorsed by golf legend Jack Nicklaus, who names author Richard Diedrich in his foreword as possibly the only person he has ever met who truly understands the synergy that must coexist between golf courses and their clubhouses. Nicklaus and Diedrich paired up more than 25 years ago to design many of the world's newest and most prestigious clubs. Many of the world's most established and legendary courses are featured, including the Augusta National Golf Club, the Winged Foot Golf Club and the Congressional Country Club, to name a few. What makes this book outstanding, however, is its presentation of many new clubs that are destined to rank among the world's legendary clubs. These include 40 recently designed and built clubs in the United States that set the standard for designing clubs around the world, which is appropriate when it is considered that more than half of the world's 32,000 golf courses can be found within the United States.
The riveting story of a dramatic confrontation between Native Americans and white settlers, a compelling conflict that unfolded in the newly created Washington Territory from 1853 to 1857. When appointed Washington’s first governor, Isaac Ingalls Stevens, an ambitious military man turned politician, had one goal: to persuade (peacefully if possible) the Indians of the Puget Sound region to turn over their ancestral lands to the federal government. In return, they were to be consigned to reservations unsuitable for hunting, fishing, or grazing, their traditional means of sustaining life. The result was an outbreak of violence and rebellion, a tragic episode of frontier oppression and injustice. With his trademark empathy and scholarly acuity, Pulitzer Prize–winner Richard Kluger recounts the impact of Stevens’s program on the Nisqually tribe, whose chief, Leschi, sparked the native resistance movement. Stevens was determined to succeed at any cost: his hasty treaty negotiations with the Indians, marked by deceit, threat, and misrepresentation, inflamed his opponents. Leschi, resolved to save more than a few patches of his people’s lush homelands, unwittingly turned his tribe—and himself most of all—into victims of the governor’s relentless wrath. The conflict between these two complicated and driven men—and their supporters—explosively and enormously at odds with each other, was to have echoes far into the future. Closely considered and eloquently written, The Bitter Waters of Medicine Creek is a bold and long-overdue clarification of the historical record of an American tragedy, presenting, through the experiences of one tribe, the history of Native American suffering and injustice.
The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates
In this sweeping interpretive history of mid-nineteenth-century Chicago, historians John B. Jentz and Richard Schneirov boldly trace the evolution of a modern social order. Combining a mastery of historical and political detail with a sophisticated theoretical frame, Jentz and Schneirov examine the dramatic capitalist transition in Chicago during the critical decades from the 1850s through the 1870s, a period that saw the rise of a permanent wage worker class and the formation of an industrial upper class. Jentz and Schneirov demonstrate how a new political economy, based on wage labor and capital accumulation in manufacturing, superseded an older mercantile economy that relied on speculative trading and artisan production. The city's leading business interests were unable to stabilize their new system without the participation of the new working class, a German and Irish ethnic mix that included radical ideas transplanted from Europe. Jentz and Schneirov examine how debates over slave labor were transformed into debates over free labor as the city's wage-earning working class developed a distinctive culture and politics. The new social movements that arose in this era--labor, socialism, urban populism, businessmen's municipal reform, Protestant revivalism, and women's activism--constituted the substance of a new post-bellum democratic politics that took shape in the 1860s and '70s. When the Depression of 1873 brought increased crime and financial panic, Chicago's new upper class developed municipal reform in an attempt to reassert its leadership. Setting local detail against a national canvas of partisan ideology and the seismic structural shifts of Reconstruction, Chicago in the Age of Capital vividly depicts the upheavals integral to building capitalism.
Provides a unique biography of Charlie Chaplin, focusing on Chaplin as a political figure, providing students with a fuller picture of the film maker by looking beyond his films. Allows students to see how Chaplin used his films as political criticisms of the Great Depression and the wars of the 20th century, enabling students to see why his films were controversial and the impact Chaplin had on popular opinion. Looks not just at the life of Charlie Chaplin but the culture and politics of the 20th century, enabling students of film history, cultural history and of 20th century history to broaden their focus and offer new ideas for assignments.
Concentrating on the eighteenth and nineteenth centuries, he traces its development up to 1878 and one of its earliest conscious articulations, Thomas Hardy's description of Egdon Heath in The Return of the Native."--BOOK JACKET.
The behavioral sciences—anthropology, sociology, psychology, economics, geography, political science—have reached a turning point as we enter the decade of the 1990s. Freed from a strict emulation of classical science methodology, while benefiting from the remarkable advances in biology and the other "hard" sciences, scholars in the behavioral scie
Recognizing the urgent need for an up-to-date review of new and innovative research on growth hormone (GH) secretagogues, this exclusive work furnishes the state of the art on the mechanisms of action, design, synthesis, evaluation, and clinical applications of GH secretagogues, including orally active and xenobiotic GH-releasing compounds. Beg
Voltage-sensitive ion channels are macromolecules embedded in the membranes of nerve and muscle fibers of animals. Despite decades of intensive research under the traditional approach of gated structural pores, the relation between the structure of these molecules and their function remains enigmatic. This book examines physically oriented approaches not covered in other ion-channel books, and it develops a new physics-based approach to the problem of molecular excitability.
The dramatic story of several generations of cavers whose exciting and dangerous explorations in Kentucky's limestone labyrinths culminated in the big connection between the Flint Ridge Cave System and Mammoth Cave, forming the longest cave in the world.
Modern Irish and Scottish Literature: Connections, Contrasts, Celticisms explores the ways Irish and Scottish literatures have influenced each other from the 1760s onwards. Although an early form of Celticism disappeared with the demise of the Celtic Revivals of Ireland and Scotland, the 'Celtic world' and the 'Celtic temperament' remained key themes in central texts of Irish and Scottish literature well into the twentieth century. Richard Barlow examines the emergence, development, and transformation of Celticism within Irish and Scottish writing and identifies key connections between modern Irish and Scottish authors and texts. By reading works from figures such as James Macpherson, Walter Scott, Sydney Owenson, Augusta Gregory, W. B. Yeats, Fiona Macleod, James Joyce, Samuel Beckett, Hugh MacDiarmid, Sorley MacLean, and Seamus Heaney in their political and cultural contexts, Barlow provides a new account of the characteristics and phases of literary Celticism within Romanticism, Modernism, and beyond.
Learn to reduce joint pain and inflammation—while avoiding surgery and medication—with this proven eight-week program! In this groundbreaking book, leading orthopedic surgeon and former NFL player Richard Diana, M.D., applies his unique experience and training to tackle the problem of joint pain. Dr. Diana draws on cutting-edge research to provide a comprehensive eight-week program proven to reduce inflammation, relieve pain, and rejuvenate your joints at the cellular level. THIS VOLUME INCLUDES: • An accessible overview of the science behind joint pain and inflammation • Which delicious foods reduce inflammation • Simple exercises tailored to your ability • The right supplements to help increase your mobility
Hardening hearts. Blinding eyes. Sending deceitful spirits. Crafting vessels of wrath. Few will deny that certain biblical passages make claims about God that are difficult to accept. But perhaps the most troubling are the verses that describe God as influencing individuals or groups towards wicked behavior for the purpose of condemning them. What are readers to do with these texts? In Vessels of Wrath, Richard M. Blaylock tackles the thorny subject of divine reprobating activity (DRA). Through an exhaustive, biblical-theological study of the Old and New Testaments, Blaylock argues that the Bible does not present DRA as an insignificant or monolithic concept; instead, the biblical authors showcase both the significance and the complexity of DRA in a variety of ways. The book aims to help readers of the Bible to wrestle with the Scriptures so that they might come to better understand its testimony to this mysterious and awesome divine activity.
This volume consists of full length manuscripts of 159 of the 165 invited papers presented at World Soybean Research Conference III that was held in the Scheman Continuing Education Building at Iowa State University August 12-17, 1984. The authors, widely recognized as world authorities in their fields, represent all aspects of soybean research activity: breeding and genetics, crop and soil management, economics, entomology, food science, international programs, nematology, pathology, physiology, plant nutrition, rhizobiology, utilization, and weed science. This proceedings, which contains more than 1200 pages of information including many tables and figures, represents the most extensive compilation of soybean research results since the previous proceedings were published in 1980. It should be of value to research scientists, students and administrators alike.
This book derives the mathematical basis for the most-encountered waves in fluids in science and engineering. It gives professionals in important occupations such as maritime engineering, climate science, urban noise control, and medical diagnostics the key formulae needed for calculations. The book begins with the basis of fluid dynamics and subsequent chapters cover surface gravity waves, sound waves, internal gravity waves, waves in rotating fluids, and introduce some nonlinear wave phenomena. Basic phenomena common to all fluid waves such as refraction are detailed. Thereafter, specialized application chapters describe specific contemporary problems. All concepts are supported by narrative examples, illustrations, and problems. FEATURES • Explains the basis of wave mechanics in fluid systems. • Provides tools for the analysis of water waves, sound waves, internal gravity waves, rotating fluid waves and some nonlinear wave phenomena, together with example problems. • Includes comprehensible mathematical derivations at the expense of fewer theoretical topics. • Reviews cases describable by linear theory and cases requiring nonlinear and wave-interaction theories. This book is suitable for senior undergraduates, graduate students and researchers in Fluid Mechanics, Applied Mathematics, Meteorology, Physical Oceanography, and in Biomedical, Civil, Chemical, Environmental, Mechanical, and Maritime Engineering.
The first edition, published in 1973, has become a classicreference in the field. Now with the second edition, readers willfind information on key new topics such as neural networks andstatistical pattern recognition, the theory of machine learning,and the theory of invariances. Also included are worked examples,comparisons between different methods, extensive graphics, expandedexercises and computer project topics. An Instructor's Manual presenting detailed solutions to all theproblems in the book is available from the Wiley editorialdepartment.
The second edition of this popular textbook presents a balanced overview of the principles of supply chain management. Going beyond the usual supply chain text, Principles of Supply Chain Management not only details the individual components of the supply chain, but also illustrates how the pieces must come together. To show the logic behind why su
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