Chemoattractant Ligands and Their Receptors succinctly summarizes cutting-edge research in the important area of chemoattraction in immunology. It explains how chemoattractant molecules mobilize immune cells to ward off attack by invading pathogens, both at a molecular and at a cellular level. Written by acknowledged experts in the field, it contains detailed molecular and structural information on each of the major chemoattractants and their receptors. Its unique multidisciplinary approach encompasses biology, immunology, protein chemistry, and molecular biology. A time-saving reference for both researchers and students.
Rothman-Simeone The Spine helps you achieve optimal outcomes in the clinical practice of spine surgery in adults and children. Drs. Harry N. Herkowitz, Steven R. Garfin, Frank J. Eismont, Gordon R. Bell, Richard Balderston, and an internationally diverse group of authorities help you keep up with the fast-paced field and get the best results from state-of-the-art treatments and surgical techniques, such as spinal arthroplasty and the latest spinal implants and equipment. An all-new full-color design and surgical videos online at www.expertconsult.com make this classic text more invaluable than ever before. Get the best results from the full range of both surgical and non-surgical treatment approaches with guidance from the world’s most trusted authorities in orthopaedic spine surgery. Find important information quickly through pearls, pitfalls, and key points that highlight critical points. Watch experts perform key techniques in real time with videos, on DVD and online, demonstrating minimally invasive surgery: SED procedure; thorascopic techniques; lumbar discectomy; pedicle subtraction osteotomy (PSO); C1, C2 fusion; intradural tumor; cervical laminoforaminoty; and much more. Apply the newest developments in the field thanks to expert advice on minimally invasive surgery, spinal arthroplasty and the latest spinal implants and equipments. See procedures clearly through an all new full-color design with 2300 color photographs and illustrations placed in context. Access the fully searchable contents of text online at www.expertconsult.com.
A year-long devotional that explores the Godly principles on which our country was founded. Experience gratitude for country and love of God with this 365-day journey through America’s historical events as Dr. Richard Lee introduces the people who established and shaped our nation, and teaches the Godly principles on which it was founded. Each devotional is followed by a Patriot Prayer and Promise. Scripture is taken from the New King James Version of the Bible.
Biobased Surfactants: Synthesis, Properties, and Applications, Second Edition, covers biosurfactant synthesis and applications and demonstrates how to reduce manufacturing and purification costs, impurities, and by-products. Fully updated, this book covers surfactants in biomedical applications, detergents, personal care, food, pharmaceuticals, cosmetics, and nanotechnology. It reflects on the latest developments in biobased surfactant science and provides case scenarios to guide readers in efficient and effective biobased surfactant application, along with strategies for research into new applications. This book is written from a biorefinery-based perspective by an international team of experts and acts as a key text for researchers and practitioners involved in the synthesis, utilization, and development of biobased surfactants. - Describes new and emerging biobased surfactants and their synthesis and development - Showcases an interdisciplinary approach to the topic, featuring applications to chemistry, biotechnology, biomedicine, and other areas - Presents the entire lifecycle of biobased surfactants in detail
Superconductivity covers the nature of the phenomenon of superconductivity. The book discusses the fundamental principles of superconductivity; the essential features of the superconducting state-the phenomena of zero resistance and perfect diamagnetism; and the properties of the various classes of superconductors, including the organics, the buckministerfullerenes, and the precursors to the cuprates. The text also describes superconductivity from the viewpoint of thermodynamics and provides expressions for the free energy; the Ginzburg-Landau and BCS theories; and the structures of the high temperature superconductors. The band theory; type II superconductivity and magnetic properties; and the intermediate and mixed states are also considered. The book further tackles critical state models; various types of tunneling and the Josephson effect; and other transport properties. The text concludes by looking into spectroscopic properties. Physicists and astronomers will find the book invaluable.
Covers all major modifications, including phosphorylation, glycosylation, acetylation, ubiquitination, sulfonation and and glycation Discussion of the chemistry behind each modification, along with key methods and references Contributions from some of the leading researchers in the field A valuable reference source for all laboratories undertaking proteomics, mass spectrometry and post-translational modification research
Compounds labeled with carbon-14 and tritium are indispensable tools for research in biomedical sciences, discovery and development of pharmaceuticals and agrochemicals. Preparation of Compounds Labeled with Tritium and Carbon-14 is a comprehensive, authoritative and up-to-date discussion of the strategies, synthetic approaches, reactions techniques, and resources for the preparation of compounds labeled with either of these isotopes. A large number of examples are presented for the use of isotopic sources and building blocks in the preparation of labeled target compounds, illustrating the range of possibilities for embedding isotopic labels in selected moieties of complex structures. Topics include: Formulation of synthetic strategies for preparing labeled compounds Isotope exchange methods and synthetic alternatives for preparing tritiated compounds In-depth discussion of carbon-14 building blocks and their utility in synthesis Preparation of enantiomerically pure isotopically labeled compounds Applications of biotransformations Preparation of Compounds Labeled with Tritium and Carbon-14 is an essential guide to the specialist strategies and tactics used by chemists to prepare compounds tagged with theradioactive atoms carbon-14 and tritium.
Stay on top of the latest scientific and therapeutic advances with the new edition of Leibel and Phillips Textbook of Radiation Oncology. Dr. Theodore L. Phillips, in collaboration with two new authors, Drs. Richard Hoppe and Mack Roach, offers a multidisciplinary look at the presentation of uniform treatment philosophies for cancer patients emphasizing the "treat for cure" philosophy. You can also explore the implementation of new imaging techniques to locate and treat tumors, new molecularly targeted therapies, and new types of treatment delivery. Supplement your reading with online access to the complete contents of the book, a downloadable image library, and more at expertconsult.com. Gather step-by-step techniques for assessing and implementing radiotherapeutic options with this comprehensive, full-color, clinically oriented text. Review the basic principles behind the selection and application of radiation as a treatment modality, including radiobiology, radiation physics, immobilization and simulation, high dose rate, and more. Use new imaging techniques to anatomically locate tumors before and during treatment. Apply multidisciplinary treatments with advice from experts in medical, surgical, and radiation oncology. Explore new treatment options such as proton therapy, which can facilitate precise tumor-targeting and reduce damage to healthy tissue and organs. Stay on the edge of technology with new chapters on IGRT, DNA damage and repair, and molecularly targeted therapies.
This book surveys the models for the origin of life and presents a new model starting with shaped droplets and ending with life as polygonal Archaea; it collects the most published micrographs of Archaea (discovered only in 1977), which support this conclusion, and thus provides the first visual survey of Archaea. Origin of Life via Archaea’s purpose is to add a new hypothesis on what are called “shaped droplets”, as the starting point, for flat, polygonal Archaea, supporting the Vesicles First hypothesis. The book contains over 6000 distinct references and micrographs of 440 extant species of Archaea, 41% of which exhibit polygonal phenotypes. It surveys the intellectual battleground of the many ideas of the origin of life on earth, chemical equilibrium, autocatalysis, and biotic polymers. This book contains 17 chapters, some coauthored, on a wide range of topics on the origin of life, including Archaea’s origin, patterns, and species. It shows how various aspects of the origin of life may have occurred at chemical equilibrium, not requiring an energy source, contrary to the general assumption. For the reader’s value, its compendium of Archaea micrographs might also serve many other interesting questions about Archaea. One chapter presents a theory for the shape of flat, polygonal Archaea in terms of the energetics at the surface, edges and corners of the S-layer. Another shows how membrane peptides may have originated. The book also includes a large table of most extant Archaea, that is searchable in the electronic version. It ends with a chapter on problems needing further research. Audience This book will be used by astrobiologists, origin of life biologists, physicists of small systems, geologists, biochemists, theoretical and vesicle chemists.
Companion to Dental Anthropology presents a collection of original readings addressing all aspects and sub-disciplines of the field of dental anthropology—from its origins and evolution through to the latest scientific research. Represents the most comprehensive coverage of all sub-disciplines of dental anthropology available today Features individual chapters written by experts in their specific area of dental research Includes authors who also present results from their research through case studies or voiced opinions about their work Offers extensive coverage of topics relating to dental evolution, morphometric variation, and pathology
Surgical Anatomy of the Ocular Adnexa is a beautifully and thoughtfully illustrated anatomical text that provides the ophthalmic surgeon or any surgeon working in the eyelid/orbital region with detailed yet concise, easy to read and understand descriptions of the anatomy in any particular region of the eyelid, orbit or nasolacrimal system. Throughout the text are clinical pearls and vignettes to help the reader appreciate why certain anatomical features are important to understand. Key anatomical concepts are highlighted and easy to visualize with real cadaver photos as well as the artists rendition of the same region. This book: - Develops a thorough understanding of the anatomy in the eyelid, orbit, nasolacriaml and periocular regions. - Fosters an appreciation of how knowledge of the anatomy leads to a better understanding of the pathophysiology of various disease processes involving the eyelid, orbit, nasolacrimal and periocular region. - Conveys the importance of anatomy in the surgical approach to various disease processes in the eyelid, orbit, nasolacrimal and periocular regions. This second edition will be an invaluable guidel to all those working in the eyelid, orbital, and nasolacrimal areas including residents, fellows and staff in ophthalmology, otolaryngology/head and neck surgery, plastic surgery and neurosurgeons working in and around the orbit.
With a focus on evidence-based, state-of-the-art information throughout, the eighth edition of Irwin and Rippe’s Intensive Care Medicine offers authoritative guidance to the wide variety of specialty physicians and non-physicians practicing in the adult intensive care environment. This comprehensive textbook covers both the theoretical and practical aspects of the field, and has been completely updated to provide encyclopedic, interprofessional coverage to support practitioners in every area of this complex field.
Employing a unique case-based approach, Ham's Primary Care Geriatrics continues to be your comprehensive source of clinical solutions for this challenging population. This gerontology medical reference book features an interdisciplinary perspective that empowers you with team-oriented knowledge on the best diagnosis, treatment, and management strategies available to address the complex needs of older adults."Overall this is a useful, well written, practical elderly medicine book, ideal for use in primary care. It is reasonable priced and an excellent addition to the bookshelf, virtual or real".Reviewed by: Dr Harry Brown, July 2014 Effectively treat your geriatric patients, and provide helpful guidance to their families, through engaging geriatric case studies that illustrate the principles and key clinical information you need. Form a definitive diagnosis and create the best treatment plans possible using the evidence-based medicine guidelines throughout. Find the information you need quickly and efficiently with a 2-color layout and consistent format, and test your knowledge with USMLE-style questions in every chapter. Offer your geriatric patients the most up-to-date treatment options available with six new chapters addressing Principles of Primary Care of Older Adults, Interprofessional Team Care, Billing and Coding, Frailty, Pressure Ulcers, and Anemia. Access the complete geriatric text online anytime, anywhere at Expert Consult, along with an online Cognitive Status Assessment with four tests and patient teaching guides, a dermatology quiz, and informative videos on Gait and Balance and Dizziness.
The Clerical Guide, Or Ecclesiastical Directory: Containing a Complete Register of the Dignities and Benefices of the Church of England, with the names of their present possessors,patrons &c. and an alphabetical list of the dignitaries and benefits clergy.
Stem cell transplantation may be complicated by treatment-related mortality and like the immune system that it regenerates has equal potential to either create and preserve or destroy. The dual nature that defines stem cells is differentiation that ultimately leads to death and self-renewal, which leads to immortality. What types of stem cells are there? How are they collected? What are their attributes and characteristics? This textbook devotes many chapters to familiarize the reader with the basic science, clinical aspects, and new questions being raised in the field of stem cell biology. Blood stem cells for tolerance and tissue regeneration are a rapidly developing research and clinical field that is being applied to autoimmune diseases. In clinical trials, autologous hematopoietic (blood) stem cells are being used to reduce the cytopenic interval following intense immune suppressive transplant regimens. While as yet not delineated, some possible mechanisms and pathways leading to tolerance after hematopoietic stem cell transplantation are suggested in these chapters. Tissue regeneration from blood stem cells is also suggested by animal experiments on stem cell plasticity or metamoirosis (i.e., change in fate) as described within this textbook. Ongoing early clinical trials on tissue regeneration from blood stem cells are described in the chapter on stem cell therapy for cardiac and peripheral vascular disease. Whether autologous hematopoietic stem cells, through the process of mobilization and reinfusion, may be manipulated to contribute to tissue repair in autoimmune diseases is a future area for translational research.
Written by clinicians, for clinicians, Cardiovascular Medicine and Surgery offers a comprehensive, authoritative, and multidisciplinary approach to this rapidly evolving field. Covering every area relevant to the daily practice of cardiovascular medicine, this new and innovative reference text, led by Drs. Debabrata Mukherjee and Richard A. Lange, brings together a stellar team of cardiovascular specialists from leading medical centers worldwide who focus on cutting-edge strategies for the clinical and surgical management of patients. Both medicine and surgery are highlighted in chapters along with follow-up care and changing technology to equip the clinician for optimal patient care. Highly structured and templated chapters cover pathogenesis, diagnosis, management, special considerations/limitations, follow-up care, and on-going and future research.
The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for students and exercise solutions for instructors.
Widely regarded as the definitive reference in the field, Youmans and Winn Neurological Surgery offers unparalleled, multimedia coverage of the entirety of this complex specialty. Fully updated to reflect recent advances in the basic and clinical neurosciences, the 8th Edition covers everything you need to know about functional and restorative neurosurgery, deep brain stimulation, stem cell biology, radiological and nuclear imaging, and neuro-oncology, as well as minimally invasive surgeries in spine and peripheral nerve surgery, and endoscopic and other approaches for cranial procedures and cerebrovascular diseases. In four comprehensive volumes, Dr. H. Richard Winn and his expert team of editors and authors provide updated content, a significantly expanded video library, and hundreds of new video lectures that help you master new procedures, new technologies, and essential anatomic knowledge in neurosurgery. - Discusses current topics such as diffusion tensor imaging, brain and spine robotic surgery, augmented reality as an aid in neurosurgery, AI and big data in neurosurgery, and neuroimaging in stereotactic functional neurosurgery. - 55 new chapters provide cutting-edge information on Surgical Anatomy of the Spine, Precision Medicine in Neurosurgery, The Geriatric Patient, Neuroanesthesia During Pregnancy, Laser Interstitial Thermal Therapy for Epilepsy, Fetal Surgery for Myelomeningocele, Rehabilitation of Acute Spinal Cord Injury, Surgical Considerations for Patients with Polytrauma, Endovascular Approaches to Intracranial Aneurysms, and much more. - Hundreds of all-new video lectures clarify key concepts in techniques, cases, and surgical management and evaluation. Notable lecture videos include multiple videos on Thalamotomy for Focal Hand Dystonia and a video to accompany a new chapter on the Basic Science of Brain Metastases. - An extensive video library contains stunning anatomy videos and videos demonstrating intraoperative procedures with more than 800 videos in all. - Each clinical section contains chapters on technology specific to a clinical area. - Each section contains a chapter providing an overview from experienced Section Editors, including a report on ongoing controversies within that subspecialty. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
This book features the major research advances on integrated networking, caching, and computing. Information-centric networking-based caching is one of the promising techniques for future networks. The cloud computing paradigm has been widely adopted to enable convenient, on-demand network access to a shared pool of configurable computing resources. In addition, fog/edge computing is proposed to deploy computing resources closer to end devices. From the perspective of applications, network, cache and compute are underlying enabling resources. How to manage, control and optimize these resources can have significant impacts on application performance.
In Introduction to Mortgages & Mortgage Backed Securities, author Richard Green combines current practices in real estate capital markets with financial theory so readers can make intelligent business decisions. After a behavioral economics chapter on the nature of real estate decisions, he explores mortgage products, processes, derivatives, and international practices. By focusing on debt, his book presents a different view of the mortgage market than is commonly available, and his primer on fixed-income tools and concepts ensures that readers understand the rich content he covers. Including commercial and residential real estate, this book explains how the markets work, why they collapsed in 2008, and what countries are doing to protect themselves from future bubbles. Green's expertise illuminates both the fundamentals of mortgage analysis and the international paradigms of products, models, and regulatory environments. - Written for buyers of real estate, not mortgage lenders - Balances theory with increasingly complex practices of commercial and residential mortgage lending - Emphasizes international practices, changes caused by the 2008-11 financial crisis, and the behavioral aspects of mortgage decision making
This book features the refereed proceedings from the 24th British National Conference on Databases, held in Glasgow, Scotland in July 2007. The eighteen full papers and seven poster papers are presented, together with two invited contributions. Papers are organized into topical sections covering data applications, searching XML documents, querying XML documents, XML transformation, clustering and security, data mining, and extraction.
Comprehensive, readable, and clinically oriented, Stoelting’s Pharmacology & Physiology in Anesthetic Practice, Sixth Edition, covers all aspects of pharmacology and physiology that are relevant either directly or indirectly to the anesthetic practice—a challenging topic that is foundational to the practice of anesthesia and essential to master. This systems-based, bestselling text has been thoroughly updated by experts in the field, giving you the detailed information needed to make the most informed clinical decisions about the care of your patients.
The first systematic survey of Healthcare Infrastructure, this book describes the inevitable future of health systems. It gives a concrete plan for improved quality at diminished cost, via merger of personal medicine and public health. It discusses general aspects of infrastructure engineering and specific aspects of healthcare systems. It discusses current and future technologies for health measurement and management. This book outlines how the health of populations will be measured at the level of individuals, combining engineering and medicine to support viable health systems for the first time. This book is unique, in combining a systematic survey of health determinants with a research monograph on health technologies. Readers will gain a broad context and a deep knowledge of future information technology applied to health systems.
What if adolescents aren't bored with preaching? What if they have and are interacting with preaching in complex, various ways that have escaped the attention of adult listeners and preachers? What if their own preaching informed the ways adults think about Christian faith and theories/practices of preaching? While much recent discussion in preaching revolves around underrepresented groups, the relationship between adolescent youth and preaching remains largely unexplored. Youthful Preaching brings youth into contemporary conversations about preaching by listening to their voices and by advocating for communities of faith and practice to seek ways to reimagine, renew, and strengthen the relationships between youth, adults, and preaching.
Advances in Anesthesia highlights the year's significant medical advances, providing one source to review the essential information updates for the Anesthesiologist in that year. The distinguished editorial board, led by Dr. Thomas McLoughlin, includes Drs. Richard Dutton, Laurence Torsher, and Francis Salinas. The board has assembled a first-rate volume for 2018, with topics including care of the severely injured orthopedic patient, patient satisfaction, emergency preparedness and mass casualty considerations, anticoagulant reversal agents, perioperative blood pressure management, postoperative management of nausea and vomiting, anesthesia for noncardiac surgery in patients with implanted LVAD, neurocognitive impact of anesthesia in children, modalities and techniques for labor epidural analgesia and anesthesia, PECS and Serratus Plane Blocks, Transversus Abdominus Plane (TAP) Blocks, cardiac dysrhythmias, right heart failure and pulmonary hypertension, and risks of "non-rate based harms.
Explores the authors' novel and provocative hypothesis that neural mechanisms controlling reproductive behavior and pain are intricately intertwined." -- Karen J. Berkley, Ph.D., Florida State University.
Textbook of Gastrointestinal Radiology remains your indispensable source for definitive, state-of-the-art guidance on all the latest and emerging GI and abdominal imaging technologies. Drs. Richard M. Gore and Marc S. Levine lead a team of world-renowned experts to provide unparalleled comprehensive coverage of all major abdominal disorders as well as the complete scope of abdominal imaging modalities, including the latest in MDCT, MRI, diffusion weighted and perfusion imaging, ultrasound, PET/CT, PET/MR, plain radiographs, MRCP, angiography, and barium studies. This edition is the perfect "go-to" reference for today’s radiologist. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Characterize abdominal masses and adenopathy with the aid of diffusion-weighted MR imaging. See how gastrointestinal conditions present with more than 2,500 multi-modality, high-quality digital images that mirror the findings you're likely to encounter in practice. Make optimal use of the latest abdominal and gastrointestinal imaging techniques with new chapters on diffusion weighted MRI, perfusion MDCT and MRI, CT colonography, CT enterography and MR enterography—sophisticated cross-sectional imaging techniques that have dramatically improved the utility of CT and MR for detecting a host of pathologic conditions in the gastrointestinal tract. Expert guidance is right at your fingertips. Now optimized for use on mobile devices, this edition is perfect as an on-the-go resource for all abdominal imaging needs. Effectively apply MR and CT perfusion, diffusion weighted imaging, PET/CT and PET/MR in evaluating tumor response to therapy.
People need a creed and a cause, and today millions of patriotic Americans are finding their voices. They say the best indicator of the future is history. How things have been can be a powerful signal of how they will be. But what will be our role in shaping the future for this country? In The Coming Revolution Dr Richard G. Lee powerfully explains that a new revolution is coming. It may be in the streets of our nation’s capitol—as we saw in Europe last year—or, better yet, in voting booths across America. Signs from our nation’s past and present ring out the truth: a second American revolution is near at hand. Using this country’s rich heritage of liberty and democracy as a roadmap toward where we could be headed, Dr. Lee brings thoughtful clarity to the ever-growing probability of such a revolution in America; illuminating the important reminder that the voices of every revolution have been—and always will be—the ordinary everyman. Discover how you can be a part of this country’s social, political, and moral reform and how faith in God serves as the one truth that can provide both individual and national guidance for America’s next revolution. “A powerful reminder about why America is great and worth fighting for.” —Lt. Colonel Oliver L. North, USMC (Ret.) “Within this book Dr. Richard Lee clearly reveals how the intolerable conditions being forced upon the American people by Washington’s current administration will lead to a certain and powerful explosion of predictable consequences.” —Michael Reagan
This text explains how firms can improve the performance of the people on whom they depend - workers, customers, suppliers, stockholders - by managing the incentives system better. The author argues that incentives are not just a matter of money, but a range of factors which provide a set of rewards that encourage people to work towards a common goal of organizational success.
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