Recognizing the urgent need for an up-to-date review of new and innovative research on growth hormone (GH) secretagogues, this exclusive work furnishes the state of the art on the mechanisms of action, design, synthesis, evaluation, and clinical applications of GH secretagogues, including orally active and xenobiotic GH-releasing compounds. Beg
Evidence based medicine has had a major impact on clinical practice. There is an urgent need for the Public Health community to further develop its own evidence base as many interventions are introduced, unchallenged with no hope of evaluation as the tools for this do not exist. This well structured text aims to provide the tools to achieve this aim. Mindful of the varying needs of students, practitioners and policy makers, the author highlights key take home messages for each and provides practical methods, and their theoretical basis, for applying evidence to the field of Public Health. Some of the methods are well established, others are newly developed by the author and colleagues. The book is aimed at all health students and practitioners, at whatever level, with the hope that the reader will apply these methods to their thinking, research and practice.
This important on proficiency testing and is essential reading for practising analytical chemists and all with an interest in the quality of analytical data.
In Counterterror Offensives for the Ghost War World: The Rudiments of Counterterrorism Policy, Richard J. Chasdi has written a groundbreaking quantitative analysis that provides new insight into which types of counterterror practices work best and which types perform poorly in particular operational environments and circumstances. For Chasdi, "effectiveness" is defined as the capacity of counterterror practices to work with "stealth"-namely, without eliciting high amounts of related follow-up terrorist assaults. He moves beyond individual country analyses to tackle an analysis of counterterror practice effectiveness based on the type of political system of the country carrying out counterterror offensives and the power level of that country within the international political system. Chasdi furthermore provides essential qualitative descriptions of national security institutions, stakeholders, and processes to frame his quantitative results in ways that tie those findings to historical and contemporary political developments.
In this controversial new book, Lathe contends that the recent rise in cases of autism spectrum disorders--ASDs--is a result of increased exposure to environmental toxicity combined with genetic predisposition.
This two-volume reference examines the translational research field of oxidative stress and ageing. It focuses on understanding the molecular basis of oxidative stress and its associated age-related diseases, with the goal of developing new methods for treating the human ageing processes.
Gioachino Rossini was one of the most influential, as well as one of the most industrious and emotionally complex of the great nineteenth-century composers. Between 1810 and 1829, he wrote 39 operas, a body of work, comic and serious, which transformed Italian opera and radically altered the course of opera in France. His retirement from operatic composition in 1829, at the age of 37, was widely assumed to be the act of a talented but lazy man. In reality, political events and a series of debilitating illnesses were the determining factors. After drafting the Stabat Mater in 1832, Rossini wrote no music of consequence for the best part of twenty-five years, before the clouds lifted and he began composing again in Paris in the late 1850s. During this glorious Indian summer of his career, he wrote 150 songs and solo piano pieces his 'Sins of Old Age' and his final masterpiece, the Petite Messe solennelle. The image of Rossini as a gifted but feckless amateur-the witty, high-spirited bon vivant who dashed off The Barber of Seville in a mere thirteen days-persisted down the years, until the centenary of his death in 1968 inaugurated a process of re-evaluation by scholars, performers, and writers. The original 1985 edition of Richard Osborne's pioneering and widely acclaimed Rossini redefined the life and provided detailed analyses of the complete Rossini oeuvre. Twenty years on, all Rossini's operas have been staged and recorded, a Critical Edition of his works is well advanced, and a scholarly edition of his correspondence, including 250 previously unknown letters from Rossini to his parents, is in progress. Drawing on these past two decades of scholarship and performance, this new edition of Rossini provides the most detailed portrait we have yet had of one of the worlds best-loved and most enigmatic composers.
In 1860, on the eve of the Civil War, Macon was a business community dedicated to supplying the needs of its citizens, of the cotton planters who grew the short-staple upland cotton, the principal foundation of wealth for the antebellum South. This book offers an encyclopedic history of Macon, Georgia, during the Civil War.
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