Richard C. Horton's Books

Difficult Hypertension

Practical management and decision making

By: Richard C Horton,Norman M Kaplan,Martin J Kendall

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Difficult Hypertension

Practical management and decision making

By: Richard C Horton,Norman M Kaplan,Martin J Kendall

Sets out the problems of dealing with, and the treatment for, difficult hypertension. The international contributors offer guidelines on how they personally would tackle the problem. The book is critical of the available evidence but also provides practical and clear guidelines for clinicians.

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Page Count

308

Publisher

CRC Press

Published Date

ISBN 10

1853172146

ISBN 13

9781853172144

The Dr. Seuss Catalog

An Annotated Guide to Works by Theodor Geisel in All Media, Writings About Him, and Appearances of Characters and Places in the Books, Stories and Films

By: Richard H.F. Lindemann

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The Dr. Seuss Catalog

An Annotated Guide to Works by Theodor Geisel in All Media, Writings About Him, and Appearances of Characters and Places in the Books, Stories and Films

By: Richard H.F. Lindemann

Theodor Seuss Geisel--known worldwide as the beloved children's author Dr. Seuss--produced a body of work that spans more than 70 years. Though most often associated with children's books, he frequently contributed cartoons and humorous essays to popular magazines, produced effective and memorable advertising campaigns ("Quick, Henry, the Flit!"), and won Oscars and Emmys for motion picture productions, animated shorts, and features. As founder and president of Beginner Books, his influence on children's book publishing was revolutionary, especially in the field of elementary readers. Geisel's prolific career--he wrote or contributed illustrations to more than 75 books, most of which have been reprinted repeatedly and translated worldwide--and his predilection for made-up creatures make this joint bibliography and iconography especially useful to readers and researchers. The exhaustive bibliography is arranged chronologically, providing full bibliographic information, including translations as they appear, reissue information, and descriptions of the binding. The iconography links more than 900 fictional names, places and terms to the works in which they appear. For the reader seeking a first edition of Quomodo Invidiosulus Nomine Grinchus Christi Natalem Abrogaverit (How the Grinch Stole Christmas! translated into Latin) or hoping to identify "abrasion-contusions" (race cars in If I Ran the Circus!), this work promises as much discovery as a walk down Mulberry Street.

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Page Count

257

Publisher

McFarland

Published Date

ISBN 10

147661895X

ISBN 13

9781476618951

The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman,Mark W. Holladay

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The Organic Chemistry of Drug Design and Drug Action

By: Richard B. Silverman,Mark W. Holladay

The Organic Chemistry of Drug Design and Drug Action, Third Edition, represents a unique approach to medicinal chemistry based on physical organic chemical principles and reaction mechanisms that rationalize drug action, which allows reader to extrapolate those core principles and mechanisms to many related classes of drug molecules. This new edition includes updates to all chapters, including new examples and references. It reflects significant changes in the process of drug design over the last decade and preserves the successful approach of the previous editions while including significant changes in format and coverage. This text is designed for undergraduate and graduate students in chemistry studying medicinal chemistry or pharmaceutical chemistry; research chemists and biochemists working in pharmaceutical and biotechnology industries. - Updates to all chapters, including new examples and references - Chapter 1 (Introduction): Completely rewritten and expanded as an overview of topics discussed in detail throughout the book - Chapter 2 (Lead Discovery and Lead Modification): Sections on sources of compounds for screening including library collections, virtual screening, and computational methods, as well as hit-to-lead and scaffold hopping; expanded sections on sources of lead compounds, fragment-based lead discovery, and molecular graphics; and deemphasized solid-phase synthesis and combinatorial chemistry - Chapter 3 (Receptors): Drug-receptor interactions, cation-p and halogen bonding; atropisomers; case history of the insomnia drug suvorexant - Chapter 4 (Enzymes): Expanded sections on enzyme catalysis in drug discovery and enzyme synthesis - Chapter 5 (Enzyme Inhibition and Inactivation): New case histories: - for competitive inhibition, the epidermal growth factor receptor tyrosine kinase inhibitor, erlotinib and Abelson kinase inhibitor, imatinib - for transition state analogue inhibition, the purine nucleoside phosphorylase inhibitors, forodesine and DADMe-ImmH, as well as the mechanism of the multisubstrate analog inhibitor isoniazid - for slow, tight-binding inhibition, the dipeptidyl peptidase-4 inhibitor, saxagliptin - Chapter 7 (Drug Resistance and Drug Synergism): This new chapter includes topics taken from two chapters in the previous edition, with many new examples - Chapter 8 (Drug Metabolism): Discussions of toxicophores and reactive metabolites - Chapter 9 (Prodrugs and Drug Delivery Systems): Discussion of antibody–drug conjugates

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Page Count

537

Publisher

Academic Press

Published Date

ISBN 10

0123820316

ISBN 13

9780123820310

Dixie Valley Synthesis

By: David Blackwell,Richard Smith,Maria Richards

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Dixie Valley Synthesis

By: David Blackwell,Richard Smith,Maria Richards

The objective of this report is to summarize U.S. Department of Energy (DOE) supported studies in the Dixie Valley geothermal area and to relate the results of those studies to other, non-DOE-supported studies that have been done in the valley during the past 40 to 50 years. This compilation of past research includes new analysis resulting in a more in-depth understanding of the geothermal system in Dixie Valley. The focus is on the basin geology and structure, thermal regime, and geothermal system geochemistry. Reservoir studies are briefly discussed.

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Page Count

437

Publisher

Lulu.com

Published Date

ISBN 10

1312911778

ISBN 13

9781312911772

The Chemical Century

Molecular Manipulation and Its Impact on the 20th Century

By: Richard J. Sundberg

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The Chemical Century

Molecular Manipulation and Its Impact on the 20th Century

By: Richard J. Sundberg

This fascinating new volume provides a comprehensive yet concise overview of the chemical aspects of some of the major innovations and changes that occurred during the 20th century, relating chemical structures and properties to real-life applications. Developed for a course taught by the author for several years at UVA, the author covers the important and consequential developments in chemistry and explains their everyday, real-life applications. These include such topics as consumer products, fossil fuel use, polymers, agriculture, food production, nutrition, explosives, and drugs. The section Molecular Biology and Its Applications includes examples of the application of biotechnology and genetic engineering.

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Page Count

520

Publisher

CRC Press

Published Date

ISBN 10

1315342030

ISBN 13

9781315342030

Book's by Richard C. Horton

Difficult Hypertension

Difficult Hypertension

The Dr. Seuss Catalog

The Dr. Seuss Catalog

The Organic Chemistry of Drug Design and Drug Action

The Organic Chemistry of Drug Design and Drug Action

Dixie Valley Synthesis

Dixie Valley Synthesis

The Chemical Century

The Chemical Century

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