The Professionals' Guide to Publishing is a practical introduction to working in the publishing industry. The authors provide a clear overview of its many functions, including editorial, production, sales and marketing; ensuring that the reader has a firm understanding of their responsibilities and how these departments work cross-functionally. Providing a thorough grounding in how publishing works including information on permissions and the current legal framework; they also examine current and enduring trends in publishing including; networking, supply chains and e-publishing.
The BIRPS Atlas presents the 100 deep seismic reflection profiles collected around the British Isles by the BIRPS Group (BIRPS - British Institutions Reflection Profiling Syndicate) at desk-top scale.
Progress in Drug Research is a prestigious book series which provides extensive expert-written reviews on a wide spectrum of highly topical areas in current pharmaceutical and pharmacological research. It serves as an important source of information for researchers concerned with drug research and all those who need to keep abreast of the many recent developments in the quest for new and better medicines.
Find out the facts behind reducing your risk of cancer with cancer-fighting foods in this updated informative and visual guide. With over 700,000 copies sold worldwide, Foods to Fight Cancer explores the link between diet and cancer with information and research backed by the scientific community. Updated and expanded to support that latest cancer research, this guide reveals the best anti-cancer foods and explains how they work in your body to fight and prevent cancer. Learn why your diet needs more berries, Omega 3s, onions, garlic, and green tea to reduce your risk. With over 100 charts, tables, and diagrams that clearly explain the facts and science behind nutrition and debunk popular myths surrounding certain foods, Foods to Fight Cancer is an essential book for anyone looking to improve their health, to have a healthy remission, to begin cancer prevention, or to support a loved one going through treatment. Adhering to recommendations from the World Cancer Research fund, Foods to Fight Cancer is a vital read that details serious dietary and lifestyle changes for the good of your health.
This is a handbook of practical techniques for making the best possible interpretation of geological structures at the map scale and for extracting the maximum amount of information from surface and subsurface maps. Quantitative methods are emphasized throughout and analytical solutions are given. Interpretation strategies are defined for GIS or CAD users, yet are simple enough to be done by hand. This book will help users produce better geological maps, judge the quality of existing maps, and locate and fix mapping errors.
A fascinating interdisciplinary approach to how everyday Western music works, and why the tones, melodies, and chords combine as they do. Despite the cultural diversity of our globalized world, most Western music is still structured around major and minor scales and chords. Countless thinkers and scientists of the past have struggled to explain the nature and origin of musical structures. In Psychoacoustic Foundations of Major-Minor Tonality, music psychologist Richard Parncutt offers a fresh take, combining music theory—Rameau’s fundamental bass, Riemann’s harmonic function, Schenker’s hierarchic analysis, Forte’s pitch-class set theory—with psychology—Bregman’s auditory scene, Terhardt’s virtual pitch, Krumhansl’s tonal hierarchy. Drawing on statistical analyses of notated music corpora, Parncutt charts a middle path between cultural relativism and scientific positivism to bring music theory into meaningful discourse with empirical research. Our musical subjectivity, Parncutt explains, depends on our past musical experience and hence on music history and its social contexts. It also depends on physical sound properties, as investigated in psychoacoustics with auditory experiments and mathematical models. Parncutt’s evidence-based theory of major-minor tonality draws on his interdisciplinary background to present a theory that is comprehensive, creative, and critical. Examining concepts of interval, consonance, chord root, leading tone, harmonic progression, and modulation, he asks: Why are some scale tones and chord progressions more common than others? What aspects of major-minor tonality are based on human biology or general perceptual principles? What aspects are culturally arbitrary? And what about colonial history? Original and provocative, Psychoacoustic Foundations of Major-Minor Tonality promises to become a foundational text in both music theory and music cognition.
This book describes and interprets the findings from archaeological excavations at the Sjovold Site, situated on the west bank of the South Saskatchewan River in the far northern Plains. It explores many features of life in ancient times, inferring, along with the cultural and historical framework, societal dimensions such as group size and gender, trade and travel as well as a wide range of daily activities.
For more than 100 years, Henry's Clinical Diagnosis and Management by Laboratory Methods has been recognized as the premier text in clinical laboratory medicine, widely used by both clinical pathologists and laboratory technicians. Leading experts in each testing discipline clearly explain procedures and how they are used both to formulate clinical diagnoses and to plan patient medical care and long-term management. Employing a multidisciplinary approach, it provides cutting-edge coverage of automation, informatics, molecular diagnostics, proteomics, laboratory management, and quality control, emphasizing new testing methodologies throughout. - Remains the most comprehensive and authoritative text on every aspect of the clinical laboratory and the scientific foundation and clinical application of today's complete range of laboratory tests. - Updates include current hot topics and advances in clinical laboratory practices, including new and extended applications to diagnosis and management. New content covers next generation mass spectroscopy (MS), coagulation testing, next generation sequencing (NGS), transfusion medicine, genetics and cell-free DNA, therapeutic antibodies targeted to tumors, and new regulations such as ICD-10 coding for billing and reimbursement. - Emphasizes the clinical interpretation of laboratory data to assist the clinician in patient management. - Organizes chapters by organ system for quick access, and highlights information with full-color illustrations, tables, and diagrams. - Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. - Includes a chapter on Toxicology and Therapeutic Drug Monitoring that discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Buying and Clearing Rights is the first work to consider the difficulties of rights clearances in all forms of media. It offers practical advice on how to plan, clear and pay for rights. Covering such areas as co-production and the co-financing of contracts, multimedia, text, pictures, footage, software, moral rights and production paperwork, this book will be of use to producers, directors, suppliers of creative material and distributors as well as academics and media studies students.
This book constitutes the thoroughly refereed post-conference proceedings of the 4th International Computer Music Modeling and Retrieval Symposium, CMMR 2007, held in Copenhagen, Denmark, in August 2007 jointly with the International Computer Music Conference 2007, ICMC 2007. The 33 revised full papers presented were carefully selected during two rounds of reviewing and improvement. Due to the interdisciplinary nature of the area, the papers address a broad variety of topics in computer science and engineering areas such as information retrieval, programming, human computer interaction, digital libraries, hypermedia, artificial intelligence, acoustics, signal processing, etc. CMMR 2007 has put special focus on the Sense of Sounds from the synthesis and retrieval point of view. This theme is pluridisciplinary by nature and associates the fields of sound modeling by analysis, synthesis, perception and cognition.
The role of the cytokine, macrophage migration inhibitory factor (MIF), in the immune response and in the immunopathogenesis of different inflammatory, autoimmune, and infectious disorders is now well established. The aim of this handbook is to provide an authoritative volume covering all aspects of MIF, from basic molecular biology to structure-function relationships, pathophysiology, genetics, and drug development.Recent studies continue to broaden considerably the role of MIF in both normal physiology and pathology, which range from such diverse areas as oncogenesis, cardiac physiology, and neurodevelopment. MIF's molecular mechanism of action in these contexts is becoming increasingly understood and the role of variant MIF alleles in different conditions continues to be defined. Unique structural features of the protein, such as an intrinsic catalytic activity, and the continuing elucidation of its receptor-dependent mechanism of action offer attractive opportunities for therapeutic intervention. This volume will provide a comprehensive synthesis of the state of the art of MIF science.
A fresh, science-backed approach to reframing our often damaging relationship with technology—with tips on ergonomics, optimal screen-time, combatting ‘brain drain’, and more. Reclaim health, happiness, and sanity in a plugged-in world with this self-help guide for the 21st-century worker suffering from burnout, Zoom fatigue, shortened attention span, and smartphone addiction. Evolution shapes behavior—and as a species, we've evolved to be drawn to the instant gratification, constant connectivity, and the shiny lights, beeps, and chimes of our ever-present devices. In earlier eras, these hardwired evolutionary patterns may have set us up for success, but today they confuse our instincts, leaving us vulnerable and stressed out from fractured attention, missed sleep, skipped meals, aches, pains, and exhaustion. So how can we avoid the pitfalls programmed into modern technology use? Tech Stress offers real, practical tools to avoid the evolutionary traps that trip us up and to address the problems associated with technology overuse. You will find a range of effective strategies and best practices to individualize your workspace (in the office and at home), reduce physical strain, prevent sore muscles, combat brain drain, and correct poor posture. The book also provides fresh insights on reducing stress and enhancing health.
Today, multidisciplinary approaches to treatment are at the heart of cancer care. They offer improved clinical outcomes, new possibilities in patient quality of life, and enable the development of true innovation in individualized treatment. To accurately reflect this modern day approach to cancer care, the content of the 6th edition of Principles and Practice of Gynecologic Oncology was written entirely by surgeons, medical oncologists, radiation oncologists, and pathologists. New to the editorial team, Dr. Andrew Berchuck has made significant contributions to the understanding of the molecular pathogenesis of ovarian and endometrial cancer in the book’s content. Every chapter of this book has been either completely rewritten or extensively updated to ensure that everyone involved in treating women with gynecologic cancer will have the most comprehensive and up-to-date information on the subject.
A comprehensive monograph of the beautiful Snowy Owl, famed for its elegant, all-white plumage. The Snowy Owl needs little introduction. This massive white owl breeds throughout the Arctic, wherever there are voles or lemmings to hunt, from Scandinavia through northern Russia to Canada and Greenland. Southerly movements in winter see North American birds travel as far south as the northern United States, while infrequent vagrants on the Shetlands and other northern isles are a magnet for birders. The Snowy Owl gives this popular bird the full Poyser treatment, with sections on morphology, distribution, palaeontology and evolution, habitat, breeding, diet, population dynamics, movements, interspecific relationships and conservation, supported by some fabulous photography. The award-winning author team also had access to Russian research literature, which is generally out of reach for Western scientists.
As our understanding of what constitutes ‘good health’ grows, so does our need to understand the psychological aspects of medicine and health, as well as the psychological interventions available in healthcare. This new edition of this bestselling textbook provides a comprehensive overview of the research, theory, application and current practices in the field, covering topics from epigenetics to social determinants of health and transdiagnostic approaches to mental health and everything in between. An essential read for all medicine and healthcare students, this text is now accompanied by a suite of online resources for all your learning needs.
Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression — A Selection of Readings for Health Services Providers presents an edited and annotated collection of recent medical journal publications and abstracts illustrating new approaches to treatment derived from the metabolic theory of cancer. It intends to shed an early light on a relatively new approach to our understanding of the cancer cell idiosyncratic metabolic dysfunction, and on evidence-based new treatment strategies derived from that understanding. The book discusses topics such as tumor starvation by L-arginine deprivation; L-canavanine depriving tumors of L-arginine in pancreatic, multiple myeloma and breast cancer; glucose deprivation and intermittent fasting; glutamine uptake in cancer; the relation of oxygen-starved cancer cells with aspartate; and reducing tolerance of tumor cells to nutrition starvation. The content is presented in a contextualized and practical way in order to facilitate the transition from bench to bedside. This is a valuable resource for practitioners, oncologists and other members of healthcare chain who are interested in learning more about the most recent tumor cell starvation strategies and how they can improve overall treatment outcome. - Provides extensive comments on scientific publications detailing recent findings about tumor cell auxotrophy applied to tumor cell starvation strategies - Helps the reader to find relevant and practical information on cancer cell starvation, otherwise spread through niched specialized journals, in one single place - Comments on the recent findings putting them in context of clinical practice in order to provide the reader with means of translating high level research to the clinics
Deep-water (below wave base) processes, although generallyhidden from view, shape the sedimentary record of more than 65% ofthe Earth’s surface, including large parts of ancientmountain belts. This book aims to inform advanced-levelundergraduate and postgraduate students, and professional Earthscientists with interests in physical oceanography and hydrocarbonexploration and production, about many of the important physicalaspects of deep-water (mainly deep-marine) systems. The authorsconsider transport and deposition in the deep sea, trace-fossilassemblages, and facies stacking patterns as an archive of theunderlying controls on deposit architecture (e.g., seismicity,climate change, autocyclicity). Topics include modern and ancientdeep-water sedimentary environments, tectonic settings, and howbasinal and extra-basinal processes generate the typicalcharacteristics of basin slopes, submarine canyons, contouritemounds and drifts, submarine fans, basin floors and abyssalplains.
To interpret the laboratory results. To distinguish the normal from the abnormal and to understand the merits and demerits of the assays under study. The book attempts to train a laboratory medicine student to achievesound knowledge of analytical methods and quality control practices, tointerpret the laboratory results, to distinguish the normal from the abnormaland to understand the merits and demerits of the assays under study.
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