- Heavily illustrated atlas covers entire development from week 1 through birth. - Enables the Radiologist or Obstetrician to monitor progress, and the Pathologist to see what went wrong. - Cross-disciplinary expertise; authors are a leading Pediatric Radiologist, a Geneticist, and an expert in abnormal pediatric skeletal development.
This thesis deals with two theories of international trade: the theory of comparative advantage, which is connected to the name David Ricardo and is dominating current trade theory, and Adam Smith’s theory of absolute advantage. Both theories are compared and their assumptions are scrutinised. The former theory is rejected on theoretical and empirical grounds in favour of the latter. On the basis of the theory of absolute advantage, developments of free international trade are examined, whereby the focus is on trade between industrial and underdeveloped countries. The main conclusions are that trade patterns are determined by absolute production cost advantages and that the gap between developed and poor countries is not reduced but rather increased by free trade.
Essay from the year 2006 in the subject Politics - Topic: International Organisations, grade: B2, University of Limerick, language: English, abstract: Introduction In March 2003 an US-led coalition declared war against the Iraq and invaded Iraq. As soon as in April the resistance of the Iraqi military ended and the ‘coalition of the willings’ came out as the winner. But until today the situation in Iraq is far away from being peaceful. Instead there are terror attacks with hundred, sometimes even thousand, of dead civilians and soldiers every month. But there is another point that led the war appears in bad light, namely that the United Nations (UN) and especially the Security Council of the UN never clearly backed this war. Furthermore the US-led coalition started the invasion disregarding the international community that was majoritarian against an attack on Iraq. But the fact that the US started the war by-passing the UN generates the question which role plays the UN nowadays in international politics? Is the UN still the only authority that has the legitimacy to decide and act in matters of international peace and security or are states paying less attention to the rules and regulations of the UN and strong states like the US act without regards to the UN and its the decisions in the future? Thus, can the UN and the Security Council restore and maintain their authority in matters of international dimension – despite the fact, that they were undermined in the Iraq war by the US (and the states that supported the US-led coalition)? Or did the unilateral Iraq War marked the ‘end of international security system’ (Glennon 2003, p.17)? The starting point of this essay is this thesis of Thierry Tardy: ‘The ill-founded war in Iraq no doubt undermined the authority of the UN Security Council, apparently unable to match US security interests. But it also holds true that the UN still matters for the overwhelming majority of actors in the “international community” and is likely to remain an inescapable pivot of security management long after the Iraq crisis is out of the headlines’ (Tardy 2004, p.591) To discuss these points this essay starts with a short introduction about the UN system and the Security Council of the UN. Afterwards I will look at the war on Iraq, how the UN and its member countries, especially the US, acted during to and after the war...
A self-contained introduction to the basic theoretical concepts, experimental techniques and recent advances in the fields of quantum communication, quantum information and quantum computation. The introductory and self-contained character of the contributions should make this book particularly attractive to students and active researchers in physics and computer science who want to become acquainted with the underlying basic ideas and recent advances in the rapidly evolving field of quantum information processing.
Get a healthy perspective on pharmaceutical economics! Strategies in Pharmacoeconomics and Outcomes Research presents a comprehensive introduction to the economic aspects of the health sector, focusing on strategies for the development and marketing of healthcare products. A much-needed addition to this relatively new field, the book narrows health economics into the sub-discipline of pharmacoeconomics, bridging the gap between different interest groups in the pharmaceutical industry-research and development at one end, sales and marketing at the other. Using basic terminology and practical examples with descriptive tables and figures, it analyzes the implications of projecting costs of pharmaceutical products as a method of determining the viability of their development. Written from an international perspective, Strategies in Pharmacoeconomics and Outcomes Research examines the costs of drug therapy on health care systems and society through global marketing and modeling strategies, including clinical research and trial examples. Through the interlinked concepts of clinical research, outcomes research and pharmacoeconomics, the book evaluates the effectiveness of health technologies under “real world” circumstances or “normal” medical practice to achieve the optimum benefit from the resources available. The research process follows the economics of a drug?s efficacy (how it works under ideal circumstances) to its effectiveness (how it does in “real” life) to its efficiency (how cost-effective it is) in determining the baseline effects of a disease on economic and humanistic parameters. Strategies in Pharmacoeconomics and Outcomes Research also examines: resources and cost benefits (direct, indirect, intangible, and quality of life) health economical models (decision-tree analysis, Markov-model) reimbursement differences between countries due to the rate of currency exchange drug monitoring and regulation . . . and includes an extensive glossary! At a time when health economics has become increasingly important, Strategies in Pharmacoeconomics and Outcomes Research is an essential tool for the pharmaceutical, diagnostic, and medical device industries to ensure the most efficient use of limited resources. The book?s practical tone and common-sense methods provide a realistic approach that will benefit pharmaceutical and medical professionals, product managers, business development managers, drug regulatory affairs officials, and clinical study coordinators in making strategic and operational decisions about pharmaceutical development, production, or consumption.
The stories of five mathematical journeys into new realms, pieced together from the writings of the explorers themselves. Some were guided by mere curiosity and the thrill of adventure, others by more practical motives. In each case the outcome was a vast expansion of the known mathematical world and the realisation that still greater vistas remain to be explored. The authors tell these stories by guiding readers through the very words of the mathematicians at the heart of these events, providing an insightinto the art of approaching mathematical problems. The five chapters are completely independent, with varying levels of mathematical sophistication, and will attract students, instructors, and the intellectually curious reader. By working through some of the original sources and supplementary exercises, which discuss and solve -- or attempt to solve -- a great problem, this book helps readers discover the roots of modern problems, ideas, and concepts, even whole subjects. Students will also see the obstacles that earlier thinkers had to clear in order to make their respective contributions to five central themes in the evolution of mathematics.
In Dust Bound for Heaven Reinhard Hütter shows how Thomas Aquinas's view of the human being as dust bound for heaven weaves together elements of two questions without fusion or reduction. Does humanity still have an insatiable thirst for God that sends each person on an irrepressible religious quest that only the vision of God can quench? Or must the human being, living after the fall, become a "new creation" in order to be readied for heaven? Hütter also applies Thomas's anthropology to a host of pressing contemporary concerns, including the modern crisis of faith and reason, political theology, the relationship between divine grace and human freedom, and many more. The concluding chapter explores the Christological center of Thomas's theology.
Nitrogen" Suppt. Vol. B 1 describes the compounds of nitrogen with noble gases and, in the major part, binary compounds composed of one nitrogen atom and hydrogen. Nitrogen hydrogen compounds with two and more nitrogen atoms are covered in "Nitrogen" Suppt. Vol. 82. There is some information on various nitrogen-noble gas species, to a large extent because of the interest in their bonding behavior. Experimental data have been obtained chiefly for some singly charged cations, particularly those formed by argon Like ArN + and ArNi. The existence of others has only been established by mass spectrometry. The binary compounds of nitrogen and hydrogen comprise NH, NH , NH , NH , the corre 2 4 5 sponding ions, and some adducts. NH and NH1 are not treated. The predominant part 3 of the volume covers the description of the molecules NH and NH . 8oth species are present 2 in photolytic processes in the atmosphere. They play an essential role in combustion systems regardless of whether the nitrogen stems from the nitrogen-containing fuel or from the air. Thus, much work has been devoted to the understanding of the nitrogen chemistry in combustion and in the atmosphere. The production and detection methods as weiL as the reactions have been comprehensively described. ln addition detailed information is given on the spectral behavior, the knowledge of which is important for detecting the mole cules and for studying their kinetics.
Dehydrobenzene and Cycloalkynes deals with the problems associated with the production and reactions of dehydrobenzene and of the related fields of dehydroheterocycles and cycloalkynes. This book also describes the various synthetic applications of dehydrobenzene and provides a list of reactions in which dehydrobenzene occurs as an intermediary. The text explains the generation of dehydrobenzene by cleavage of cyclic systems, by photolytic methods, and by free radical reactions. Nucleophilic and electrophilic monodentate attacks on dehydrobenzene, as well as, bidentate additions to dehydrobenzene yielding cycloadducts. The book also notes that dehydrobenzene is not only a transition state but can be an intermediate of characteristic selectivity and lifetime. The reactions of dehydrobenzene in the gaseous phase affirm that the existence of dehydrobenzene is not restricted to the presence of a solvation shell. The researcher can then study the molecular structure of dehydrobenzene when its existence has been fully established. The text also extends the principle that the dehydroaromatic intermediates can be obtained by abstracting two adjacent hydrogen atoms from an aromatic substrate different from the 1- and 2- positions to arrive at a 1,3- and 1,4-dehydrobenzene. Researchers and scientists whose works are associated with organic chemistry, analytical chemistry, molecular physics or physical chemistry will find this book valuable.
Understanding the atomic structure of complex and time disordered materials relies upon computer simulations of these structures. This cook book provides a unique mixture of simulation know-how and hands on examples. All related files and the program DISCUS are included on a CDROM with the book.
The integration of sustainability requires a paradigm shift in the lifecycle of buildings. By using the BIM method, aspects of sustainable construction can be increasingly integrated into processes and workflows. Information is captured consistently and in a structured way across the lifecycle and made available to all stakeholders. This Essential presents the current status quo of possible applications of the BIM method in sustainable construction. The aim is to promote a fusion of BIM and sustainability by highlighting essential requirements for BIM processes and models, workflows and their added value.
This is the first book which brings together the fields of theoretical and empirical studies in syntax on the one hand and the methodology of quantitative linguistics on the other hand. The author provides the theoretical background for this enterprise on the basis of the philosophy of science and of linguistic considerations including a discussion of Chomsky’s attitude against the application of statistical methods to syntactic phenomena. He gives a short introduction into the aims and methods of the quantitative approach to linguistics in general and to syntax in particular. The following chapters inform the reader about the measurement of syntactic properties, possibilities to acquire empirical data from syntactically annotated text corpora and the most common mathematical models and methods for the analysis of syntactic and syntagmatic material. Then, a number of prominent approaches and hypotheses about interrelations between properties of syntactic constructions are presented and evaluated on material from various languages and text kinds. Finally, the theory of synergetic linguistics and its application to syntax is introduced including the integration of such famous hypotheses as Yngve’s depth hypothesis and Hawkins’s "Early immediate constituent" principle. The book concludes with a number of perspectives with respect to follow-up studies and extensions to the presented models with interfaces to neighbouring disciplines.
This book examines the circumstances under which a company needs restructuring, and for which companies that would be possible given the nature of the corporation and the economic viability. It discusses the criteria for judging whether a reorganization has been a success. Bork considers the legal mechanisms involved in restructuring including the extent to which the law provides the rules for a moratorium and the rights creditors may exercise over the debtor's assets. It also tackles the legal processes and how a reorganization can be commenced. The book includes analysis of the role of management and the partners or shareholders and the extent to which either legal system assigns the decision-making powers to the right persons. It considers how each regime deals with the assets involved and whether there are rules to reverse payments made during the crisis and the possibility of a set-off claim. Other aspects considered include special rules for terminating or modifying disadvantageous contracts including contracts of employment, and costs of restructuring procedures under given legal conditions. Providing a thorough consideration of the extent to which English and German company law (including the proposed changes to German law) enhances or limits the prospects of businesses seeking to reorganize, this work offers a valuable reference source for practitioners advising companies on where to base their restructuring and gives scholars further research material concerning the remaining issues in English and German restructuring law.
Chronic conditions and diseases are the leading cause of mortality and morbidity in Europe, accounting for 86% of total premature deaths, and research suggests that complex conditions such as diabetes and depression will impose an even greater health burden in the future - and not only for the rich and elderly in high-income countries, but increasingly for the poor as well as low- and middle-income countries. The epidemiologic and economic analyses in the first part of the book suggest that policy-makers should make chronic disease a priority. This book highlights the issues and focuses on the strategies and interventions that policy-makers have at their disposal to tackle this increasing challenge. Strategic discussed in the second part of this volume include (1) prevention and early detection, (2) new provider qualifications (e.g. nurse practitioners) and settings, (3) disease management programmes and (4) integrated care models. But choosing the right strategies will be difficult, particularly given the limited evidence on effectiveness and cost-effectiveness. In the third part, the book therefore outlines and discusses institutional and organizational challenges for policy-makers and managers: (1) stimulating the development of new effective pharmaceuticals and medical devices, (2) designing appropriate financial incentives, (3) improving coordination, (4) using information and communication technology, and (5) ensuring evaluation. To tackle these challenges successfully, key policy recommendations are made.
This book presents recent developments in automatic text analysis. Providing an overview of linguistic modeling, it collects contributions of authors from a multidisciplinary area that focus on the topic of automatic text analysis from different perspectives. It includes chapters on cognitive modeling and visual systems modeling, and contributes to the computational linguistic and information theoretical grounding of automatic text analysis.
The Bibliography of Quantitative Linguistics (BQL) comprises more than 6500 titles from all areas of quantitative linguistic research. Publications have been included without restrictions regarding form, place, language, and date of publication. This bibliography thus provides, for the first time, a comprehensive overview of, and easy bibliographical access to, publications in quantitative linguistics, a linguistic discipline characterized by its rapid and promising scientific development, and its increasing significance for most branches of theoretical and applied language studies. The bibliography consists of: an introduction and instructions for use; a main section containing more than 6500 titles, which is subdivided in 28 thematic classes, each forming a chapter; an index of authors; an index of keywords from titles; indices of subject headings and subheadings; an index of uncontrolled vocabulary; an index of languages investigated; an index of reviewed publications. All texts and indices are in English, German and Russian.
Multiple Sclerosis 3 emphasizes the latest in the pharmacologic treatment of this incurable inflammatory demyelinating disorder. Primary editors Claudia Lucchinetti, MD, and Reinhard Hohlfeld, MD, with the aid of all new contributors, present a complete and current reference on multiple sclerosis that includes discussions of such hot topics as Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair. Distinguish between MS and other similar demyelinating disorders and know the best and most aggressive methods of treatment. This title in the Blue Books of Neurology series is exactly what you need to treat the disease and its relapses. Covers the latest clinical advances and relevant discussions—Biomarkers, Genomics, and Surrogate Outcomes in MS; Pediatric MS; Transverse Myelitis; Attack Therapies in MS; Current Disease-Modifying Therapeutic Strategies in MS; Management of Aggressive MS; Symptomatic Therapies in MS; Complementary and Alternative Medical Therapies; and Strategies to Promote Neuroprotection and Repair—to bring you up to date and keep your practice state-of-the-art. Features a greater emphasis on practical management to help you determine the type of multiple sclerosis and the best course of therapy. Focuses on pharmaceutical therapies so you know the best and most aggressive methods and which drugs to use for treatment. Includes extensive information on differential diagnosis so that you can clearly distinguish between multiple sclerosis and other similar demyelinating disorders. Presents expert new editors and experienced contributing authors for the most current and relevant practice information. Emphasizes the pharmacologic management of patients with multiple sclerosis to address treating the actual disease and its relapses as well as treating the symptoms.
The wealth of insights into the brain’s functioning gained by neuroscience in recent years led to the development of new possibilities for intervening in the brain such as neurotransplantation, neural prostheses and brain stimulation techniques. Moreover, new and safer classes of psychopharmaceutical drugs lend themselves to neuroenhancement applications, i.e. they could be used to enhance cognitive capacities or emotional well-being without therapeutic need. This book offers extensive state-of-the-art accounts for these novel kinds of intervention, indicates future developments, and discusses the relevant philosophical, ethical and legal issues.
This second edition, which combines the features of an atlas and a textbook, presents findings in forensic histology, immunohistochemistry, and cytology based on microscopic investigations using different stainings and different antibodies. Questions of quality when working in the field of forensic histology are included as well as scientific perspectives for further research. The principal aim is to provide practitioners with detailed information and guidance on how microscopy can help to clarify the cause of sudden and unexpected death. Therefore additional and particularly rare histopathological findings are presented. Many of the topics will be of interest not only to forensic pathologists but also to general pathologists, whether practitioners or researchers. Examples include the pathology of drug abuse, wound age determination, adverse drug reactions, histopathology of the sudden infant death syndrome, and age determination of myocardial infarction. Both typical and unusual findings are demonstrated with the aid of numerous high-quality color illustrations, and other key literature in forensic histology and immunohistochemistry is highlighted for each topic.
Intended for juniors and seniors majoring in mathematics, as well as anyone pursuing independent study, this book traces the historical development of four different mathematical concepts by presenting readers with the original sources. Each chapter showcases a masterpiece of mathematical achievement, anchored to a sequence of selected primary sources. The authors examine the interplay between the discrete and continuous, with a focus on sums of powers. They then delineate the development of algorithms by Newton, Simpson and Smale. Next they explore our modern understanding of curvature, and finally they look at the properties of prime numbers. The book includes exercises, numerous photographs, and an annotated bibliography.
The volume describes all compounds that consist of bromine and fluorine and/or chlorine and may additionally contain noble gases, hydrogen, oxygen, and nitrogen. The description of chemical and physical properties of binary compounds between bromine and fluorine takes up most of the volume, because this class of compounds includes BrF3 and BrF5 which have considerable technical interest. Especially the the oxidizing and fluorinating properties of BrF3 make it a convenient reactant for the preparation of inorganic fluorides. On the other hand, the diatomic molecule BrF is well-characterized by spectroscopic methods, but its chemistry is less known because of its instability. Other neutral species, such as Br2F, Br2F2, BrF2, and BrF6, only exist in matrices at low temperatures, and the existence of BrF4 and BrF7 is even doubted. Some of the ions, including BrF2+, BrF2-, Br3F10-, BrF4+, BrF4-, BrF6+, and BrF6-, can be stabilized as salts.
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