Reena Sharma's Books

Hindu Women's Property Rights in Rural India

Law, Labour and Culture in Action

By: Reena Patel

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Hindu Women's Property Rights in Rural India

Law, Labour and Culture in Action

By: Reena Patel

Hindu women in India have independent right of ownership to property under the Law of Succession (The Hindu Succession Act, 1956). However, during the last five decades of its operation not many women have exercised their rights under the enactment. This volume addresses the issue of Hindu peasant women's ability to effectuate the statutory rights to succession and assert ownership of their share in family land. The work combines a critical evaluation of law with economic analyses into allocation of resources within the family as a means of addressing gender relations and explaining resulting gender inequalities.

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246

Publisher

Routledge

Published Date

ISBN 10

1351156381

ISBN 13

9781351156387

Female Infanticide in India

A Feminist Cultural History

By: Rashmi Dube Bhatnagar,Renu Dube,Reena Dube

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Female Infanticide in India

A Feminist Cultural History

By: Rashmi Dube Bhatnagar,Renu Dube,Reena Dube

Female Infanticide in India is a theoretical and discursive intervention in the field of postcolonial feminist theory. It focuses on the devaluation of women through an examination of the practice of female infanticide in colonial India and the reemergence of this practice in the form of femicide (selective killing of female fetuses) in postcolonial India. The authors argue that femicide is seen as part of the continuum of violence on, and devaluation of, the postcolonial girl-child and woman. In order to fully understand the material and discursive practices through which the limited and localized crime of female infanticide in colonial India became a generalized practice of femicide in postcolonial India, the authors closely examine the progressivist British-colonial history of the discovery, reform, and eradication of the practice of female infanticide. Contemporary tactics of resistance are offered in the closing chapters.

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335

Publisher

State University of New York Press

Published Date

ISBN 10

0791483851

ISBN 13

9780791483855

Self-Help to Raintree English Class 8

FOR 2021 EXAMINATIONS

By: Reena Sidhu

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Self-Help to Raintree English Class 8

FOR 2021 EXAMINATIONS

By: Reena Sidhu

Solutions of OrientBlackswan Raintree English class 8 It includes solutions of Coursebook, Workbook and Literature Reader.

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247

Publisher

Ravinder Singh and sons

ISBN 10

9388395336

ISBN 13

9789388395335

Application of AI

By: Dr. Surender Kumar Yadav,Prof. (Dr.) B. K. Sarkar,Prof. (Dr.) Reena Singh,Prof. (Dr.) Vandana Singh

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Application of AI

By: Dr. Surender Kumar Yadav,Prof. (Dr.) B. K. Sarkar,Prof. (Dr.) Reena Singh,Prof. (Dr.) Vandana Singh

IoT stands for the Internet of Things. It refers to the network of physical objects or "things" embedded with sensors, software, and other technologies that enable them to connect and exchange data with other devices and systems over the internet. These objects can range from everyday items such as household appliances, wearable devices, and vehicles to industrial machines and infrastructure components.

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311

Publisher

GEH Press

Published Date

ISBN 10

819760794X

ISBN 13

9788197607943

Critical Response To Literatures In English

By: Reena Mitra

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Critical Response To Literatures In English

By: Reena Mitra

The Present Book Contains A Varied Selection Of Essays Ventured Upon As Exercises In Critical Evaluation Of Texts That Are Relevant In The Existent Literary Context. These Essays Are Certainly Not A Random Pick For Each Of The Works Chosen For Analysis, Whatever Be The Genre Of Writing, Represents The Literature In English Produced By The Native Writers Of A Particular Country. The Two Major Literatures In English Are Indisputably Those Of England And America But There Are Many Other Countries Like Africa, Australia, India And Pakistan Whose Authors Chose To Write In English Because They Felt That English, Despite Being An Alien Language, Would Better Verbalize Their Creative Urge And Lend Itself To An Exploration Of The Immense Possibilities Therein. Most Of The Authors Taken Up For Study In This Book Are Those Who Belong To The Fraternity Of Indian English Writers, Namely Mulk Raj Anand, Shashi Deshpande, Salman Rushdie, Vikram Seth, Mahesh Dattani And Manju Kapur. Catering To A Revival Of Interest In The Partition Of India As A Theme In Fiction Are Two Essays Which Deal With The Issue. Other Write-Ups Are On Works (Some In Translation) By Native Writers Of Hitherto Marginalized Countries That Have Now Chosen To Aggressively Assert Themselves Through Their Respective Literatures.The Book, Comprehensive And Rich In Its Contents, Is Highly Informative And Would Prove An Asset To Those Interested In The Diverse Manifestations Of Literature In English. It Would Be Of Particular Appeal To Those Who Wish To Explore The Works Of Indian English Writers Of Repute.

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264

Publisher

Atlantic Publishers & Dist

Published Date

ISBN 10

8126905859

ISBN 13

9788126905850

Animal Behaviour

By: Reena Mathur

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Animal Behaviour

By: Reena Mathur

1. Introduction to the Study of Animal Behaviour 2. Concepts of Ethology 3. Methods of Studying Behaviour 4. Mammalian Nervous System and Behaviour 5. Pheromones 86-108 6. Hormones and Behaviour 7. Biological Clocks 8. Orientation 9. Bird Migration and Navigation 10. Fish Migration 11. Social Organization 12. Wildlife 10 India Glossary Supplementary Reading

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296

Publisher

Rastogi Publications

Published Date

ISBN 10

8171337473

ISBN 13

9788171337477

Param Vir Chakra

By: Reena I. Puri

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Param Vir Chakra

By: Reena I. Puri

The Param Vir Chakra is the highest decoration of valour in wartime, awarded to members of the Indian Armed Forces. The men who have been awarded this ultimate honour displayed indomitable courage and selfless devotion to duty, while defending the borders of our nation. It is only the most fearless who can summon the will to stand their ground and fight the enemy in the face of death. Only the bravest can challenge the ultimate sacrifice, so that no one else has to. Amar Chitra Katha tells the stories of 21 fearless heroes, for whom their own lives were less important than the sovereignty of India, and the safety of their fellow citizens. 21 stirring tales of bravery, courage and sacrifice, that need to be told and remembered, as an inspiration for generations to come.

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251

Publisher

Amar Chitra Katha Pvt Ltd

Published Date

ISBN 10

9350858428

ISBN 13

9789350858424

The English Circle Workbook 07

By: Reena Shukla

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The English Circle Workbook 07

By: Reena Shukla

This series is a multi-skill structured course in English with an intense focus on grammar structure practised through the LSRW skills. Some of the key features of this series include HOTS, Life skills, exercises based on the principle of multiple intelligences and learn-by-doing methods as well as projects and sample test papers to evaluate all skills.

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New Saraswati House India Pvt Ltd

ISBN 10

935272254X

ISBN 13

9789352722549

Ultrasound Technology in Green Chemistry

By: Mika Sillanpää,Thuy-Duong Pham,Reena Amatya Shrestha

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Ultrasound Technology in Green Chemistry

By: Mika Sillanpää,Thuy-Duong Pham,Reena Amatya Shrestha

As a new and rapidly growing science, the applications of ultrasound methods in environmental technology hold a promising future. Compared to conventional methods, ultrasonication can bring several benefits such as being environmentally friendly (no toxic chemical are used or produced), low cost, and compact, allowing on-site treatment. Besides an overview featuring the background behind ultrasonic technology, this brief summarizes the main studies and innovations reported in recent research that has utilized ultrasound methods in environmental analysis, water, and sludge treatment, soil and sediment remediation to air purification.

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Springer Science & Business Media

Published Date

ISBN 10

9400724098

ISBN 13

9789400724099

Know Your State Haryana

By: Sohan Singh Kattar,Reena Kar

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Know Your State Haryana

By: Sohan Singh Kattar,Reena Kar

1. Know Your State’ series provides the entire description of the state 2. Present edition on Haryana has been divided into 6 Units 3. It provides Chapterwise theory for thorough learning 4. More than 1100 MCQs are provided for practice 5. Special section for Current Affairs for a quick look 6. The book contains detailed information on “Haryana” along with latest current updates 7. Highly useful for HPSC and other state-level exams. ‘Know Your State – Haryana’ that has been designed as a reference book to provide comprehensive information about the state. This book provides detailed study of History, Geography, Economy, Polity, Art & Culture, Centre and State Government welfare schemes in a systematic chapter by chapter manner that results in the marked improvement in the performances of the students. A separate section has been allotted to Current Affairs. Theories given in the book are supported by Box, Tables, Map, and Figures for the clear presentation that leads better understanding among readers. Multiple Choice Questions are provided at end of each chapter which test the understanding each concept from exam point of view. Students who are preparing for Haryana Public Service Commission (HPSC) and other state level exams will find this book as quick relevant and easy route for achieving success in the examination. TABLE OF CONTENT Haryana Basic Information, Ancient History of Haryana, Medieval History of Haryana, Modern History of Haryana, Geographical Features and Climate of Haryana, Drainage System of Haryana, Soil and Mineral Resources in Haryana, Forest and Wildlife of Haryana, Agriculture and Animal Husbandry of Haryana, Industries of Haryana, Energy and Irrigation Resources in Haryana, Transportation and Communication in Haryana, Tourism in Haryana, Formation of Haryana State, Haryana Legislative and State Structure, Haryana Judiciary, Haryana Local Self Government District Profile of Haryana, Language and Literature of Haryana, Arts and Crafts of Haryana, Music and Dance of Haryana, Fairs and Festivals of Haryana, Sports in Haryana, Education in Haryana, Famous Personalities of Haryana, Awards and Honors in Haryana, Social Welfare Scheme in Haryana, Demographic Profile of Haryana, Current Affairs.

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322

Publisher

Arihant Publications India limited

Published Date

ISBN 10

9325293994

ISBN 13

9789325293991

Reimagining India-thailand Relations: A Multilateral And Bilateral Perspective

By: Reena Marwah

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Reimagining India-thailand Relations: A Multilateral And Bilateral Perspective

By: Reena Marwah

This book brings into focus India's relations with ASEAN and Thailand in particular. In the 1990s, India revived its relations with Southeast Asia. Yet, in comparison to China, India continued to be a distant neighbour. Hence, India has once again, through its 'Look and Act East' policies become intertwined with its immediate neighbours in the East, especially with Thailand. The objective of the book is to contextualise India's relations and influence in Southeast Asia over a period of nearly two thousand years, through culture and religion. The scope of the book extends beyond bilateral issues to include the multilateral, bringing in issues of trade negotiations under the Regional Comprehensive Economic Partnership (RCEP) and the Indo-Pacific construct. As ASEAN's importance grows in the regional and global landscape, there are ramifications for its relations with its traditional partners. The volatility and suspicion among the major powers, especially USA and China harbour the potential to disunite ASEAN. A rising India seeks a united and strong ASEAN both as a natural partner and in a bid to balance China's growing assertiveness and deep pockets. Based on interviews conducted with experts , diplomats and scholars in the field, this book encompasses a wide range of aspects that pertain to the historical, cultural, economic and strategic international relations of ASEAN and Thailand with India.

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318

Publisher

World Scientific

Published Date

ISBN 10

9811212058

ISBN 13

9789811212055

The English Circle Class 08

By: Reena Shukla

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The English Circle Class 08

By: Reena Shukla

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156

Publisher

New Saraswati House India Pvt Ltd

ISBN 10

9352722175

ISBN 13

9789352722174

From Quetta to Delhi: A Partition Story

By: Reena Nanda

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From Quetta to Delhi: A Partition Story

By: Reena Nanda

This story is a cameo set against the backdrop of Partition - a decision taken by political leaders in Britain and India that shattered the lives of ordinary people like the family in this narrative who at that time were living in Quetta, Baluchistan. Viewing victims of the Partition of Punjab in the light of post traumatic stress has been long overdue. The narrator's mother's method of coping with the traumatic present was to escape into the past by reliving her memories of Quetta and her beloved Pathans along with the mundane, insignificant little details of the women's daily lives. Her recall hinges on the drama of the trivial, on food,rituals, clothes, religious practices and neighbourhood bonding. It was a syncretic culture, of multilinguism - Urdu,Punjabi and Seraiki, Persian and Sanskrit, of multiple identities through the biradaris - caste,mohalla and religion. The author's grandmother kept the Guru Granth Sahib at home, her mother and sisters practiced Hindu rituals, while her husband was an agnostic. And everyone made pilgrimages to Sufi pirs.

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158

Publisher

Bloomsbury Publishing

Published Date

ISBN 10

9386643448

ISBN 13

9789386643445

India–Vietnam Relations

Development Dynamics and Strategic Alignment

By: Reena Marwah,Lê Thị Hằng Nga

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India–Vietnam Relations

Development Dynamics and Strategic Alignment

By: Reena Marwah,Lê Thị Hằng Nga

This book provides an in-depth analysis of the close cultural links between India and Vietnam. It discusses the issues of trade negotiations under the Regional Comprehensive Economic Partnership (RCEP) and the Indo-Pacific construct. Issues such as strengthening the economic partnership, contemporary development challenges posed by the COVID-19 pandemic, including weakening supply chains, and geo-strategic tensions are explored in this book. It enriches understanding of the potential of the two countries to develop as manufacturing hubs for the region and beyond. Given the more aggressive posturing by China in 2020, the concluding chapter includes the policy prescriptions with a futuristic vision, for India and Vietnam to catalyze their strategic and bilateral partnership. Well researched and analytical, the book draws extensively from several interviews of experts, diplomats, journalists, businesspersons, and members of the diaspora. It is a must read for students, researchers, think tanks, area study centers, and all institutions engaged in Asian studies, encompassing narratives extending from the developmental to political, from the bilateral to the multilateral and from the geo-economic to the geo-strategic.

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Page Count

227

Publisher

Springer Nature

Published Date

ISBN 10

9811678227

ISBN 13

9789811678226

Abiotic And Biotic Stress Management In Plants

Volume 01 Abiotic Stress

By: Bhav Kumar Sinha,Reena

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Abiotic And Biotic Stress Management In Plants

Volume 01 Abiotic Stress

By: Bhav Kumar Sinha,Reena

This book deals with an array of topics in the broad area of abiotic stress responses in plants focusing “problems and their management” by selecting some of the widely investigated themes. Such as, Cell signalling in Plants during abiotic and biotic stress, Salinity stress induced metabolic changes and its management, High temperature stress: responses, mechanism and management, Low temperature stress induced changes in plants and their management, Biotechnological approaches to improve abiotic stress tolerance, Nutritional poverty in wheat under abiotic stress scenario, Strategies for improving soil health under current climate change scenario, Abiotic stress management in Pulse crops, Mitigation strategies of abiotic stress in fruit crops, Impacts of abiotic stress and possible management option in vegetable crops, and Abiotic stress: impact and management in ornamental crops. This book is useful for under-graduate and post-graduate students in Plant Physiology, Biochemistry, agronomy, horticulture, Botany, Environmental sciences and other cognate disciplines of agriculture and allied sciences and other research workers. We fervently believe that this book will provide good information and understanding of abiotic stress problems and their management in plants.

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New India Publishing Agency

Published Date

ISBN 10

9386546574

ISBN 13

9789386546579

Working the Night Shift

Women in India’s Call Center Industry

By: Reena Patel

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Working the Night Shift

Women in India’s Call Center Industry

By: Reena Patel

Relatively high wages and the opportunity to be part of an upscale, globalized work environment draw many in India to the call center industry. At the same time, night shift employment presents women, in particular, with new challenges alongside the opportunities. This book explores how beliefs about what constitutes "women's work" are evolving in response to globalization. Working the Night Shift is the first in-depth study of the transnational call center industry that is written from the point of view of women workers. It uncovers how call center employment affects their lives, mainly as it relates to the anxiety that Indian families and Indian society have towards women going out at night, earning a good salary, and being exposed to western culture. This timely account illustrates the ironic and, at times, unsettling experiences of women who enter the spaces and places made accessible through call center work. Visit the author's website at http://www.working-the-nightshift.com and Facebook group at www.facebook.com/WorkingtheNightShift.

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287

Publisher

Stanford University Press

Published Date

ISBN 10

0804775508

ISBN 13

9780804775502

China's Economic Footprint In South And Southeast Asia: A Futuristic Perspective - Case Studies Of Pakistan, Sri Lanka, Myanmar And Thailand

By: Reena Marwah,Sanika Sulochani Ramanayake

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China's Economic Footprint In South And Southeast Asia: A Futuristic Perspective - Case Studies Of Pakistan, Sri Lanka, Myanmar And Thailand

By: Reena Marwah,Sanika Sulochani Ramanayake

The labyrinthine BRI projects, aimed at realizing win-win benefits, have created new challenges for the host countries. Economic aspirations must be shielded and protected by security umbrellas, thus making these countries partners of the China-dominated security architecture. Nowhere is this more evident than in the countries of Sri Lanka and Pakistan. Despite Southeast Asian nations being viewed as within the ambit of China's historical sphere of influence, Myanmar and Thailand provide experiences different from their neighbours. This book analyzes China as an economic juggernaut, undergirded by global ambitions, expanding its economic footprint across South and Southeast Asia through trade, technological supremacy and territorial acquisitions. The authors also navigate China's policies at home and abroad, providing a futuristic perspective on China's path to victory. The book provides answers to compelling questions as:

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Page Count

357

Publisher

World Scientific

Published Date

ISBN 10

9811236399

ISBN 13

9789811236396

Pharmaceutical Organic Chemistry -E-Book

By: S.K. Bhasin,Reena Gupta

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Pharmaceutical Organic Chemistry -E-Book

By: S.K. Bhasin,Reena Gupta

Pharmaceutical Organic Chemistry has been written keeping in mind the severe need for a comprehensive text to meet the curriculum needs of the undergraduate pharmacy students. It not only provides all the curriculum topics to the students but also contains all the vital reactions/mechanisms that the students look for in an organic chemistry book. - Entire subject matter has been written in a systematic and lucid style in simple language. - All the basic concepts and fundamentals of organic chemistry have been explained with well-chosen examples. - For better understanding of the subject matter, important points have been highlighted in the form of the textboxes titled as Remember, Learning Plus and Noteworthy Points, wherever required. - Summary of the topics in the form of Memory Focus has been given at relevant places to help the students to revise the subject matter quickly. - Stepwise mechanism of the reactions as per the syllabus has been illustrated, laying emphasis on the reactive intermediates involved. - At the end of each chapter, Revision Questions including descriptive questions and short answer questions have been given for the students to practice. Multiple Choice Questions with answers have been included at the end of each chapter.

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Page Count

819

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

8131232670

ISBN 13

9788131232675

Satyajit Ray's The Chess Players and Postcolonial Film Theory

Postcolonialism and Film Theory

By: Reena Dube

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Satyajit Ray's The Chess Players and Postcolonial Film Theory

Postcolonialism and Film Theory

By: Reena Dube

Indispensable for students of film studies, in this book Reena Dube explores Satyajit Ray's films, and The Chess Players in particular, in the context of discourses of labour in colonial and postcolonial conditions. Starting from Daniel Defoe and moving through history, short story and film to the present, Dube widens her analysis with comparisons in which Indian films are situated alongside Hollywood and other films, and interweaves historical and cultural debates within film theory. Her book treats film as part of the larger cultural production of India and provides a historical sense of the cross genre borrowings, traditions and debates that have deeply influenced Indian cinema and its viewers.

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271

Publisher

Springer

Published Date

ISBN 10

0230509665

ISBN 13

9780230509665

Engineering Mathematics-I

By: Reena Garg

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Engineering Mathematics-I

By: Reena Garg

This book is designed to meet the complete requirements of Engineering Mathematics course of undergraduate syllabus, The book consists of seven chapters viz. infinite Series, Matrices, Expansion of Functions, Asymptotes, Curvature, Partial Differenciation , Multiple Integrals, Each chapter is treated in treated in systematic,logical and lucid manner, All these chapters are independent units in themselves. The students can go through the book picking up any chapter at any given times, without referring to other chapters, Hints, where ever necessary and answers of the questions in the exercises are given at the end of each exercise, Most of the questions-solved as well as unsolved-have been picked up from the examination papers of different universities and professional examinations, There are fully worked out examples and graded exercises (with answers) aimed at preparing the student for examination as well as higher studies, The authors have illustrated various methods to solve particular problems.

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2019

Publisher

KHANNA PUBLISHING HOUSE

Published Date

ISBN 10

9382609555

ISBN 13

9789382609551

The Indus Valley Adventure

By: Reena Ittyerah Puri

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The Indus Valley Adventure

By: Reena Ittyerah Puri

Vijay and Durga have no idea what they are in for when they accompany their amateur archaeologist grandfather to the excavation site of the Indus Valley civilization. Quite annoyed that they have to spend their holidays in a dusty dump they are hardly prepared for the amazing adventure that takes them back 3390 years to a world that they have only read about in their history books. An adventure that involves a clay whistle, a boy called Vala and his pet goat. Amar Chitra Katha presents a very special story that brings to life one of the most ancient civilizations of the world.

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Amar Chitra Katha Pvt Ltd

Published Date

ISBN 10

818482937X

ISBN 13

9788184829372

Connecting Places, Connecting People

A Paradigm for Urban Living in the 21st Century

By: Reena Tiwari

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Connecting Places, Connecting People

A Paradigm for Urban Living in the 21st Century

By: Reena Tiwari

What is a better community? How can we reconfigure places and transport networks to create environmentally friendly, economically sound, and socially just communities? How can we meet the challenges of growing pollution, depleting fossil fuels, rising gasoline prices, traffic congestion, traffic fatalities, increased prevalence of obesity, and lack of social inclusion? The era of car-based planning has led to the disconnection of people and place in developed countries, and is rapidly doing so in the developing countries of the Global South. The unfolding mega-trend in technological innovation, while adding new patterns of future living and mobility in the cities, will question the relevance of face-to-face connections. What will be the ‘glue’ that holds communities together in the future? To build better communities and to build better cities, we need to reconnect people and places. Connecting Places, Connecting People offers a new paradigm for place making by reordering urban planning principles from prioritizing movement of vehicles to focusing on places and the people who live in them. Numerous case studies, including many from developing countries in the Global South, illustrate how this can be realized or fallen short of in practical terms. Importantly, citizens need to be engaged in policy development, to connect with each other and with government agencies. To measure the connectivity attributes of places and the success of strategies to meet the needs, an Audit Tool is offered for a continual quantitative and qualitative evaluation.

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173

Publisher

Routledge

Published Date

ISBN 10

1315449226

ISBN 13

9781315449227

The Crux - Stories Inspired by Real Life

By: Dr.Reena Walia

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The Crux - Stories Inspired by Real Life

By: Dr.Reena Walia

Born at Ambala (Haryana), the authoress is a cheerful, positive, friendly, God fearing, and hardworking person. She runs a school "Zenith Public School" which is upto Tenth in Jalandhar; Punjab. Also a social organization in the name of" Bachpan Pratinishtha"- an organization that takes care of health and education of destitute kids of Jalandhar. She has an artistic bent of mind and is fond of reading and writing. She is 16 years young with 42 years of experience. (58 years, just kidding) and with her B.Sc (Non.Med), M.A(English), B.Ed, M.Ed, M.Phil (English),PhD(English) she strives for perfection at home and equally at work. She has contributed to various anthologies and magazines such as ‘Be The One', Mentor, Being Mindful and कश्फ़ Many prizes to her credit in various online poetry competitions such as Poet of the month, Inspiring women's award, Be The One award and gold medals, trophies and first, second and third positions. Five published books, namely- Emotional Reverberation, Dialogics of Narrative Techniques in Salman Rushdie's Midnight Children, Carnivalesque in Salman Rushdie's Fictional Rendition, Judge for an open mike competition, Modulator of poetic group Shabdanchal Rajasthan and Sahitya Sarovar. She hates cheeky people and gets put- off with their stupid shrewdness (so to say). She has a loving family, wonderful staff at school and cooperative team at the NGO. She loves life and thanks God for all the blessings. Life couldn't have been better, it's totally blissful.

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129

Publisher

JEC PUBLICATION

ISBN 10

9358500719

ISBN 13

9789358500714

Textbook of Nursing Education 3E - E-Book

By: Suresh Sharma,Reena Sharma

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Textbook of Nursing Education 3E - E-Book

By: Suresh Sharma,Reena Sharma

Chapter-I: Review of the Communication Process Chapter-2: Interpersonal Relationship Chapter-3: Human Relations Chapter-4: Guidance and Counselling Chapter-5: Principles of Philosophy of Education Chapter-6: Teaching-Learning Process Chapter-7: Methods of Teaching Chapter-8: Educational Media Chapter-9: Assessment & Evaluation Chapter-10: Information, Education and Communication for Health Chapter-11: - Nursing Education in India Updated MCQs and other review questions (short and long answer) Flowcharts, Diagrams and Images added for better and easy understanding Aligned as per the INC syllabus for UGs and reference for PG nursing students Working Examples of Clinical teaching methodologies provided

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977

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

8131261573

ISBN 13

9788131261576

Molecular Genetics of Thalassemia Syndromes

By: Reena Das,Prashant Sharma

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Molecular Genetics of Thalassemia Syndromes

By: Reena Das,Prashant Sharma

This book reviews the molecular genetics of the thalassemia syndromes, inherited hemoglobin disorders that comprise the commonest monogenic disorders globally. Thalassemias are found in high frequencies in tropical regions corresponding to the malaria belt. Beta thalassemia traits show high HbA2 by HPLC, and β-globin mutations (commonly point mutations) are detected by using ARMS-PCR, reverse dot-blot analysis and β-globin gene sequencing. Globally >300 β globin gene mutations exist, however regional mutations are limited to 5-6 common ones. Alpha globin gene defects can only be identified by molecular tests, the exception being HbH disease that shows "golf ball" appearance in HbH preparation, pre-integration peaks on HPLC and a fast-moving band on hemoglobin electrophoresis. Multiplex Gap-PCR identifies common α-globin gene deletions. Specific PCR across the junction caused by the unequal crossing over can detect α-gene triplication. However, heterozygosity or homozygous triplication cannot be resolved by this technique. Non-deletional α-thalassemia can be characterized by specific α-globin gene sequencing. Identification of unusual deletions requires Multiplex Ligation-dependent Probe Amplification. In conclusion, the molecular characterization of human globin gene disorders is required to resolve the phenotypically heterogeneous thalassemia syndromes. Molecular analysis is also an important tool to prevent these disorders by offering prenatal screening in regions with a high disease burden.

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Solve jigsaw puzzle

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Publisher

Biota Publishing

Published Date

ISBN 10

1615047255

ISBN 13

9781615047253

Book's by Reena Sharma

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