The fourth edition of this classic text provides a thorough, yet concise review of the cellular and molecular mechanisms involved in the transformation of normal into malignant cells, the invasiveness of cancer cells into host tissues, and the metastatic spread of cancer cells in the host organism. It defines the fundamental pathophysiologic changes that occur in tumor tissue and in the host animal or patient. Each chapter discusses the historical development of a field, citing the key experimental advances to the present day, and evaluates the current evidence that best supports or rules out concepts of the molecular and cellular mechanisms regulating cancer cell behavior. For all the areas of fundamental cancer research, an effort has been made to relate basic research findings to the clinical disease states. The book is well written and well illustrated, with schematic diagrams and actual research data to demonstrate points made in the text. There is also an extensive, up-to-date bibliography, making the book valuable to scientists, and to physicians, students, and nurses interested in the field of cancer biology. The topics covered include pathologic characterization of human tumors, epidemiology of human cancer, regulation of cell proliferation and differentiation, cellular and molecular phenotypic characteristics of the cancer cell, mechanisms of carcinogenesis, tumor initiation and promotion, viral carcinogenesis, oncogenes and oncogene products, growth factors, chromosomal alterations in cancer, mechanisms of tumor metastasis, host-tumor interactions, fundamental aspects of tumor immunology, and the advances in cancer cell biology that will lead to improved diagnosis and treatment of cancer in the future.
Two of America’s foremost fly-fishing authors join forces in this unique book offering guidance to others who aspire to write about fly fishing. Paul Schullery and Steve Raymond, both members of the Fly Fishing Hall of Fame, have separately written many fly-fishing books, both fiction and nonfiction, and edited three fly-fishing magazines. Here they offer the benefit of their many years of experience to help others who aspire to write about the sport, including everything you need to know about developing your personal writing style, how to write and sell fly-fishing magazine articles or books, how to find publishers, how to promote and sell your work, or how to self-publish.
Fundamental Accounting Principles remains the most successful introductory accounting text in Canada. The 10th Canadian Edition benefits from a winning new author team, and a research and development process that is unprecedented in Canadian College Publishing. The result is a highly market driven text that responds to the evolving needs of today's classroom. The text's hallmarks; readability, superior problem material and high production value; have been expanded and improved, reflecting extensive user and reviewer feedback. With a sole proprietor focus, the text patiently brings the student into the accounting cycle and the key financial statements, with an appreciation for the role and importance of the accounting function stressed throughout.The 10 c/e is available in 3 volumes, or in a hardbound financial accounting version.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.