Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
In a compelling, honest, and transparent account, Ralph Friesen tells the story of his father, Reverend Peter D. Friesen of Steinbach, Manitoba. He also tells his own story, of the search for his father and a crisis of faith. Growing up in a fundamentalist Mennonite community as the son of a minister, Ralph resisted the pressure to be “saved” and struggled to find a spiritual alternative. His father suffered a debilitating stroke when Ralph was a young teenager, but it is only now, in his seventies, that Ralph has delved into the meaning of that event. Dad, God, and Me is Ralph’s quest to discover and convey the man his father was—with all of his strengths, faults, aspirations, and regrets. Drawing on journal entries, old photographs, and personal memories, this memoir welcomes readers into a particular time, place, and family. An engaging read for anyone who appreciates that “real life” can be challenging, painful, and beautiful all at the same time.
An examination of the ways that digital and networked technologies have fundamentally changed research practices in disciplines from astronomy to literary analysis. In Knowledge Machines, Eric Meyer and Ralph Schroeder argue that digital technologies have fundamentally changed research practices in the sciences, social sciences, and humanities. Meyer and Schroeder show that digital tools and data, used collectively and in distributed mode—which they term e-research—have transformed not just the consumption of knowledge but also the production of knowledge. Digital technologies for research are reshaping how knowledge advances in disciplines that range from physics to literary analysis. Meyer and Schroeder map the rise of digital research and offer case studies from many fields, including biomedicine, social science uses of the Web, astronomy, and large-scale textual analysis in the humanities. They consider such topics as the challenges of sharing research data and of big data approaches, disciplinary differences and new forms of interdisciplinary collaboration, the shifting boundaries between researchers and their publics, and the ways that digital tools promote openness in science. This book considers the transformations of research from a number of perspectives, drawing especially on the sociology of science and technology and social informatics. It shows that the use of digital tools and data is not just a technical issue; it affects research practices, collaboration models, publishing choices, and even the kinds of research and research questions scholars choose to pursue. Knowledge Machines examines the nature and implications of these transformations for scholarly research.
Global security, climate and health challenges have called into question our capacity to cope with change. Criticizing mainstream norm, practice and realist theory, Jason Ralph offers a 'Pragmatic Constructivist' theory of learning, which is then used to assess international society's problem-solving capacities.
Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book’s sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face. Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints. Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms. Apply the latest therapeutic advances through new chapters in bioengineering and tissue engineering, as well as up-to-date coverage of gout and disease-modifying drugs. Learn how the study of biomarkers across populations can help you detect diseases earlier and with greater accuracy with a new chapter on epigenetics. Diagnose, monitor, and manage rheumatic disease more effectively with expanded information on the use of ultrasound and other imaging modalities.
This catalogue coincides with an exhibition at the NRW-Forum, 27 September 2014 - 11 January 2014, presenting for the first time in Germany, the entire photographic spectrum of 50 years of Meyerowitz's photography.Apart from the early black and white and colour photography of the 1960s, images from all working projects such as Cape Light, Portraits, Between the Dog and the Wolf and Ground Zero are presented and allow the visitor both a photographic and cultural comparison between Europe and the U.S.A.Alongside William Eggleston and Stephen Shore, Joel Meyerowitz is one of the most important representatives of the New Color Photography movement of the 1960s/70s. His early street photography of New York and the achromatic view of light at Cape Cod in particular remain icons of contemporary photography to this day.This beautiful catalogue includes texts by Jörg Sasse, Ralph Goertz and Joel Meyerowitz.English and German text.
Professor Goldman has contributed articles and books in divers fields of political science. This is a partial collection of his principal published and unpublished journal articles as well as brief references to his principal books. Professor Goldman's years at Michigan State and San Francisco State Universities provided opportunities for instructional experimentation and management of educational programs: at MSU, the American Politics Graduate Training Program; at San Francisco State, experiments in small-group peer-instruction. Other experiments: self-paced instruction; an assessment program for political science majors, and simulations of disarmament conferences. His RolePlay is an innovative teaching program for K-12 social studies.
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