Fungal spores play an important role in plant pathology and human respiratory allergy. concentration of microspores in the atmosphere is the result of complex interaction between biological and environmental factors. A better understanding of these phenomena with details of airborne particles of a particular geography helps in better management of fungal disease. A detailed study of aero mycoflora of Darbhanga urban - a small densely populated town reflects that the environmental factors may have some effect on seasonal variation of spore types. This book will be justified to check mycotoxicolgical impact of the mycoflora on the human population of Darbhanga district. This will give an understanding of the correlation of mycoflora and mycotoxin for future research.