Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. - Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field - Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise - Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients
This book addresses the mapping of soil-landscape parameters in the geospatial domain. It begins by discussing the fundamental concepts, and then explains how machine learning and geomatics can be applied for more efficient mapping and to improve our understanding and management of ‘soil’. The judicious utilization of a piece of land is one of the biggest and most important current challenges, especially in light of the rapid global urbanization, which requires continuous monitoring of resource consumption. The book provides a clear overview of how machine learning can be used to analyze remote sensing data to monitor the key parameters, below, at, and above the surface. It not only offers insights into the approaches, but also allows readers to learn about the challenges and issues associated with the digital mapping of these parameters and to gain a better understanding of the selection of data to represent soil-landscape relationships as well as the complex and interconnected links between soil-landscape parameters under a range of soil and climatic conditions. Lastly, the book sheds light on using the network of satellite-based Earth observations to provide solutions toward smart farming and smart land management.
As countries strive for a strong recovery and to recoup the losses incurred during the COVID-19 pandemic, they need to map out a new path for development and high and sustained growth. Promoting diversification, developing new industrial capabilities, and designing the policies needed to achieve this goal should be a priority. A successful diversification strategy should tackle both broad policy failures, such as an unfavorable business environment and investment climate and sector-specific market failures. This departmental paper presents a conceptual framework to analyze industrial policy, defined as targeted sectoral interventions. The authors first discuss the key principles that should guide policymakers, that is, a focus on the market failures that could justify targeted sectoral interventions, as well as the potential government failures that can undermine these interventions. The authors then discuss some commonly employed policy tools, their rationale, and the associated pitfalls. Finally, the authors outline a stylized decision-making framework.
South Asia’s Path to Sustainable and Inclusive Growth highlights the remarkable development progress in South Asia and how the region can advance in the aftermath of the COVID-19 pandemic. Steps include a renewed push toward greater trade and financial openness, while responding proactively to the distributional impact and dislocation associated with this structural transformation. Promoting a green and digital recovery remains important. The book explores ways to accelerate the income convergence process in the region, leveraging on the still-large potential demographic dividend in most of the countries. These include greater economic diversification and export sophistication, trade and foreign direct investment liberalization and participation in global value chains amid shifting regional and global conditions, financial development, and investment in human capital.
The Japanese word, Ikigai means 'reason for being'. Think of what you love, what you are good at, what you can be paid for, and what the world needs. When these come together, you get your Ikigai. However, Ikigai can be beyond these four components and doesn't have to include any or all of them. The moments each day where you live fully — engaging in a hobby or pursuit, learning, connecting with people, being useful, choosing empathy over apathy, and being in the present — and the small joys that inhabit those moments make your Ikigai. You can have more than one Ikigai and it can change with time. You already have your Ikigai and just need to discover it!The book unveils the life journeys of 25 teens that left India for the uncharted waters of Singapore in the 1990s and early 2000s. Each story started with engineering and took the person to one's calling — dance, filmmaking, entrepreneurship, mountaineering, philanthropy, research, and even monkhood. Did they find their Ikigai? Uncover the pages to find out!
Cellular, Molecular and Environmental Contribution in Cardiac Remodeling: From Lab Bench to Clinical Perspective consolidates the most recent research advances on cellular, molecular, biochemical, and heterogeneous factors contributing to the physiological and pathological cardiac remodeling, elucidating their mechanisms of action and the clinical outcomes of cardiac remodeling. It extensively covers the factors determining cardiac remodeling, including cardiomyocyte regeneration, cardiac stem cells and their therapeutic potential, cardiac resident pericytes, the role of natural bioactive compounds in cardiac remodeling, chronic cardiac adaptations to exercise and more. This book provides basic science researchers and clinical investigators in cardiology with a current and comprehensive resource on molecular mechanisms and contributing factors to cardiac remodeling, and its effects and impacts on heart health. New research areas for the future, aimed at preventing, limiting, and reversing bad remodeling, are also discussed. - Provides a concise summary of recent developments in cardiac remodeling research, combining novel information and the latest data published in this field - Discusses not only cellular and molecular factors impacting cardiac remodeling, but also environmental contributions such as lifestyle and exercise - Identifies areas for future research and potential novel strategies for translating basic research knowledge to applications in patients
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