‘Draws on ingenious insights and lessons from nature to emphasize the importance of imbibing, developing, listening to and trusting your intuition – increasingly becoming a differentiator in senior circles – to develop the confidence to take that leap of faith which every risk-bearing decision entails’ – Ratan Tata Managers can become like stunted plants. The absence of intuition – or its inadequate use – has the effect of constricting a manager. The Case of the Bonsai Manager is the perfect antidote for every manager who feels they are not achieving their full potential. Effective leadership is not just about hard facts but also about listening to, and using, your intuition. Using anecdotes from nature and the world of management, R. Gopalakrishnan explores how you can be more intuitive, inclusive and humane. The revised and updated edition of this best-selling book, with its easy-to-read anecdotal style, has additional material to reinforce the key messages, including a new self-help workbook. ‘Exceptional . . . R. Gopalakrishnan is a formidable writer and manager’ – Economic Times ‘One of the most refreshing and useful books on management that I have read in many years’ – Business Today
Advances in computers and biotechnology have had a profound impact on biomedical research, and as a result complex data sets can now be generated to address extremely complex biological questions. Correspondingly, advances in the statistical methods necessary to analyze such data are following closely behind the advances in data generation methods. The statistical methods required by bioinformatics present many new and difficult problems for the research community. This book provides an introduction to some of these new methods. The main biological topics treated include sequence analysis, BLAST, microarray analysis, gene finding, and the analysis of evolutionary processes. The main statistical techniques covered include hypothesis testing and estimation, Poisson processes, Markov models and Hidden Markov models, and multiple testing methods. The second edition features new chapters on microarray analysis and on statistical inference, including a discussion of ANOVA, and discussions of the statistical theory of motifs and methods based on the hypergeometric distribution. Much material has been clarified and reorganized. The book is written so as to appeal to biologists and computer scientists who wish to know more about the statistical methods of the field, as well as to trained statisticians who wish to become involved with bioinformatics. The earlier chapters introduce the concepts of probability and statistics at an elementary level, but with an emphasis on material relevant to later chapters and often not covered in standard introductory texts. Later chapters should be immediately accessible to the trained statistician. Sufficient mathematical background consists of introductory courses in calculus and linear algebra. The basic biological concepts that are used are explained, or can be understood from the context, and standard mathematical concepts are summarized in an Appendix. Problems are provided at the end of each chapter allowing the reader to develop aspects of the theory outlined in the main text. Warren J. Ewens holds the Christopher H. Brown Distinguished Professorship at the University of Pennsylvania. He is the author of two books, Population Genetics and Mathematical Population Genetics. He is a senior editor of Annals of Human Genetics and has served on the editorial boards of Theoretical Population Biology, GENETICS, Proceedings of the Royal Society B and SIAM Journal in Mathematical Biology. He is a fellow of the Royal Society and the Australian Academy of Science. Gregory R. Grant is a senior bioinformatics researcher in the University of Pennsylvania Computational Biology and Informatics Laboratory. He obtained his Ph.D. in number theory from the University of Maryland in 1995 and his Masters in Computer Science from the University of Pennsylvania in 1999. Comments on the first edition: "This book would be an ideal text for a postgraduate course...[and] is equally well suited to individual study.... I would recommend the book highly." (Biometrics) "Ewens and Grant have given us a very welcome introduction to what is behind those pretty [graphical user] interfaces." (Naturwissenschaften) "The authors do an excellent job of presenting the essence of the material without getting bogged down in mathematical details." (Journal American Statistical Association) "The authors have restructured classical material to a great extent and the new organization of the different topics is one of the outstanding services of the book." (Metrika)
Since mathematical models express our understanding of how nature behaves, we use them to validate our understanding of the fundamentals about systems (which could be processes, equipment, procedures, devices, or products). Also, when validated, the model is useful for engineering applications related to diagnosis, design, and optimization. First, we postulate a mechanism, then derive a model grounded in that mechanistic understanding. If the model does not fit the data, our understanding of the mechanism was wrong or incomplete. Patterns in the residuals can guide model improvement. Alternately, when the model fits the data, our understanding is sufficient and confidently functional for engineering applications. This book details methods of nonlinear regression, computational algorithms,model validation, interpretation of residuals, and useful experimental design. The focus is on practical applications, with relevant methods supported by fundamental analysis. This book will assist either the academic or industrial practitioner to properly classify the system, choose between the various available modeling options and regression objectives, design experiments to obtain data capturing critical system behaviors, fit the model parameters based on that data, and statistically characterize the resulting model. The author has used the material in the undergraduate unit operations lab course and in advanced control applications.
This Book, Based On A Study Carried Out In The Travancore Region Of Kerala, Attempts To Explain The Differential Influeces Of Many Demographic, Developmental And Cultural Variables That Influence Social Change Among Different Religious Groups And Also Ultimately The Fertility Behaviour.
Operations Management: Managing Global Supply Chains takes a holistic, integrated approach to managing operations and supply chains by exploring the strategic, tactical, and operational decisions and challenges facing organizations worldwide. Authors Ray R. Venkataraman and Jeffrey K. Pinto address sustainability in each chapter, showing that sustainable operations and supply chain practices are not only attainable, but are critical and often profitable practices for organizations to undertake. With a focus on critical thinking and problem solving, Operations Management provides students with a comprehensive introduction to the field and equips them with the tools necessary to thrive in today’s evolving global business environment.
Over the last century, medicine has come out of the "black bag" and emerged as one of the most dynamic and advanced fields of development in science and technology. Today, biomedical engineering plays a critical role in patient diagnosis, care, and rehabilitation. As such, the field encompasses a wide range of disciplines, from biology and physiolo
This international technology assessment study has focused on the emerging global trend toward the miniaturization of manufacturing processes, equipment and systems for microscale components and products. The study has investigated both the state-of-the-art as well as emerging technologies from the scientific, technological, and commercialization perspectives across key industrial sectors in the USA, Asia and Europe.
Master the full range of colorectal procedures performed today with Atlas of Surgical Techniques for the Colon, Rectum, and Anus. In this volume in the Surgical Techniques Atlas Series, top authorities provide expert, step-by-step guidance on surgery of the large bowel, rectum, and anus - including both open and closed approaches for many procedures - to help you expand your repertoire and hone your clinical skills. Rely on definitive, expert guidance from the same respected authorities that made Campbell-Walsh Urology the most trusted clinical reference source in the field. Assess and deepen your understanding of key information with answers and rationales for more than 2,800 board-style multiple-choice study questions. Over 2,800 board-style multiple-choice questions provide a realistic simulation of the actual board experience. Deepen your grasp of critical concepts by studying supporting pathology and radiologic images and understanding their correlation to key points. Benefit from the consistency of all questions, answers, and rationales re-written by a single author. Measure your proficiency with interactive self-assessment questions online. Get the most from your board prep by pairing this review with its parent text, Campbell-Walsh Urology, for detailed explanations and an enhanced learning experience.
Neelakanta Theerthapada; disciple of Chattampi Swamikal was a great scholar, poet, and social and religious reformer and was a lead figures of renaissance in Kerala. He has composed numerous works in Sanskrit and Malayalam. They became the theoretical base for the movements of the marginalized and were the agents that heralded social reformers. His works formed the most important contributions from Kerala to the spiritual and philosophical literature in Sanskrit of the twentieth century. After Sankara, there was no other scholar from Kerala who has composed Sanskrit works in quality and quantity to the extent to which Neelakanta Theerthapada has done. Any serious observation of the works of Theerthapada can reveal that they excel Brhatkatha of Gunadhya, beautiful words of Murari, meaningfulness of Bharavi, compositions of Kalidasa, works of Mayura, and Magha. With the use of simple and direct words they outshine Naishadha of Sri Harsha and Karporamanjari of Rajasekhara. This is the first book in English on the life and work of Neelakanta Theerthapada.
This issue of Medical Clinics, guest edited by Drs. Marc Shalaby and Edward Bollard, is devoted to Quality Patient Care: Making Evidence-Based, High Value Choices. Articles in this issue include: Cardiovascular testing in asymptomatic patients: carotid duplex, cardiac stress testing, screen for PVD; Utility of echocardiogram in the evaluation of heart murmurs; Evidenced-based recommendations for the evaluation of palpitations in the primary care setting; Radiologic evaluation of common orthopedic complaints: low back pain, non-traumatic knee/shoulder/hip pain, and ankle injuries; Indications and usefulness of common injections for non-traumatic orthopedic complaints – shoulder, trochanteric bursa, epidural injections, tennis elbow, and knee; The evidence-based evaluation of chronic cough; Evaluation of uncomplicated headache; Evaluation of syncope; Pre-operative assessment: Cataract surgery, pre-operative EKG testing, screening for cardiopulmonary disease, urinalysis, coagulation studies, other lab assessments; The approach to occult GI bleed; The role of EGD surveillance for patients with Barrett’s esophagus; The evidence-based evaluation of iron deficiency anemia; Cancer screening in the elderly; Utilization and safety of common over the counter dietary/nutritional supplements, herbal agents and homeopathic compounds for disease prevention; Utilization of oxygen for the patient with dyspnea; IV fluids, enteral or parenteral nutrition; and Symptom control at the end of life.
Since 1954, Campbell-Walsh Urology has been internationally recognized as the pre-eminent text in its field. Edited by Alan J. Wein, MD, PhD(hon), Louis R. Kavoussi, MD, Alan W. Partin, MD, PhD, Craig A. Peters, MD, FACS, FAAP, and the late Andrew C. Novick, MD, it provides you with everything you need to know at every stage of your career, covering the entire breadth and depth of urology - from anatomy and physiology through the latest diagnostic approaches and medical and surgical treatments. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Be certain with expert, dependable, accurate answers for every stage of your career from the most comprehensive, definitive text in the field! Required reading for all urology residents, Campbell-Walsh Urology is the predominant reference used by The American Board of Urology for its board examination questions. Visually grasp and better understand critical information with the aid of algorithms, photographs, radiographs, and line drawings to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Stay on the cutting edge with online updates. Get trusted perspectives and insights from hundreds of well-respected global contributors, all of whom are at the top and the cutting edge of their respective fields. Stay current with the latest knowledge and practices. Brand-new chapters and comprehensive updates throughout include new information on perioperative care in adults and children, premature ejaculation, retroperitoneal tumors, nocturia, and more! Meticulously revised chapters cover the most recent advancements in robotic and laparoscopic bladder surgery, open surgery of the kidney, management of metastic and invasive bladder cancer, and many other hot topics! Reference information quickly thanks to a new, streamlined print format and easily searchable online access to supplemental figures, tables, additional references, and expanded discussions as well as procedural videos and more at www.expertconsult.com.
In the hamlet of Pookkudi in Tamil Nadu, an archaeological team excavates a mysterious statuette of a woman in black granite. The localities seem to know who the woman was, and folklores about her life are well-known and the team too is convinced of these. Yet, Ananthan a young archaeologist in the team, keeps questioning the authenticity of these claims. In the interregnum of a fortnight awaiting the carbon dating result, Ananthan pays a visit to his octogenarian grandfather whose health is in a sinking state. The old man, a former professor, has written a novel based on the history of Travancore and Tamil Nadu. The story is set two hundred years ago around the unnatural death of Ranganatha Deekshithar, a famous musician, and Kaveri, an eminent dancer, who is convicted of this murder by the royal police. He wrote the story based on the facts revealed to him and the assumptions he could make thereof. But he always felt there was something amiss. He believes that unless the story is cleared, his soul would not leave the nest of his body. He wants his scion, Ananthan, to take up the mission of rewriting it in line with historical facts so that he can die peacefully. From then on, Ananthan traverses through the dark recesses of history, which is embellished by music, dance, love, deception, revenge, and murder. What is the real story? Will the carbon dating results prove his theory to be correct? Will he be able to unfold the mystery and find who committed the murder, how, and why?
Interfacial Science for Geosystems Engineers provides geoscientists the connections between the nano-scale physico-chemical interactions between fluids and minerals and the core/field-scale observations to manage energy extraction, water resources and subsurface storage, timely topics central to the energy transition. Packed with latest research and recent developments, chapter learning objectives, and illustrative diagrams, tables and charts throughout, this specialized volume will help geosystems engineers tackle the above challenges, by systematically going through the basics of surface and interfacial tension, capillarity, surfactants, surface free energy, adsorption, electrokinetics, colloidal stability, equilibrium and stability of thin liquid films, wettability, microemulsions, emulsions and foams, and polymers for subsurface applications. Useful as a teaching, training or reference text, Interfacial Science for Geosystems Engineers prepares today's subsurface scientists and engineers to tackle two pressing problems in the energy transition, by introducing recent developments on how to remove CO2 from our environment and how to wean ourselves off fossil energy while meeting growing energy demands. - Describes fundamentals and recent advances in interface and nanoparticle/colloid dispersion science - Offers critical analysis of the latest research and developments relevant to extracting low-carbon and other energy materials from, and store CO2 and H2 in, subsurface formations - Helps guide geosystems (especially energy) engineers on how to solve the problems they encounter in the rapidly evolving Energy Transition
This open access book provides both a broad perspective and a focused examination of cow care as a subject of widespread ethical concern in India, and increasingly in other parts of the world. In the face of what has persisted as a highly charged political issue over cow protection in India, intellectual space must be made to bring the wealth of Indian traditional ethical discourse to bear on the realities of current human-animal relationships, particularly those of humans with cows. Dharma, yoga, and bhakti paradigms serve as starting points for bringing Hindu—particularly Vaishnava Hindu—animal ethics into conversation with contemporary Western animal ethics. The author argues that a culture of bhakti—the inclusive, empathetic practice of spirituality centered in Krishna as the beloved cowherd of Vraja—can complement recently developed ethics-of-care thinking to create a solid basis for sustaining all kinds of cow care communities.
Compiles the most current information on the Zika virus and its associated diseases This comprehensive book provides the most up-to-date information for students, medical students, and scientists on Zika virus and its associated diseases. It includes all the information related to the Zika virus since its discovery in 1947; its epidemic outbreak in 2007-2014; how the epidemiology changed in America in 2015-2016; its mode of transmission; how to prevent and treat it; and associated diseases. Zika Virus and Diseases: From Molecular Biology to Epidemiology offers complete and up-to-date coverage in 10 chapters. It presents information from papers that attempted to associate the virus with diseases in Africa until the first animal experiment; discusses its association with Guillain-Barré syndrome and microcephaly; describes the basic mechanisms for Zika (ZIKV) replication, including important differences between Dengue (DENV), West-Nile virus (WNV), and ZIKV; explains the difference between the strains and discusses the pathogenesis of them; covers the papers that showed all the interferences that Zika can cause, and the pathways which can be modified; and more. The first book since 1947 to put together all the scientific information Compiles all the information received in the last year about Zika virus Clearly demonstrates the origin and discovery of the virus Zika Virus and Diseases: From Molecular Biology to Epidemiology will appeal to graduate students, medical students, basic researchers, clinicians in infectious disease, microbiology, and virology, as well as people in related disciplines interested in learning more about this topic.
This issue of the Urologic Clinics is unique in that it examines the Controversies in Female Pelvic Reconstruction from both the urology and urogynecology standpoint. Areas of controversy regarding evaluation and therapy for a number of conditions unique to women's health are examined. Topics covered include urethral bulking, robotic/laparoscopic prolapse repair, management of bladder pain syndromes, and urodynamics.
Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.
This book presents the first behavioral activation (BA) program to help 12- to 18-year-olds overcome depression. The authors provide a systematic framework for increasing adolescents' engagement in rewarding activities and decreasing avoidant behavior. User-friendly features include session-by-session guidelines and agendas, sample scripts, and instructional materials. Strategies are described for actively involving parents and tailoring BA to each teen's needs and developmental level. In a large-size format for easy photocopying, the book contains 35 reproducible handouts. Purchasers get access to a Web page where they can download and print the reproducible materials.
Waldenström macroglobulinemia (WM) is a rare lymphoplasmacytic lymphoma characterized by the presence of an immunoglobulin M (IgM) monoclonal protein. WM is a chronic, indolent disease, which can remain undiagnosed for years. A better understanding of the role of signaling pathways in the development of the disease and the identification of clinical and genetic markers have driven the development of targeted therapeutic strategies, improving overall survival.
This revised edition provides updated fluid mechanics measurement techniques as well as a comprehensive review of flow properties required for research, development, and application. Fluid-mechanics measurements in wind tunnel studies, aeroacoustics, and turbulent mixing layers, the theory of fluid mechanics, the application of the laws of fluid mechanics to measurement techniques, techniques of thermal anemometry, laser velocimetry, volume flow measurement techniques, and fluid mechanics measurement in non-Newtonian fluids, and various other techniques are discussed.
Intended for an audience of graduate students, executive MBA students, and mid-to upper level government and corporate managers, Design, Analysis and Optimization of Supply Chains: A System Dynamic Approach examines the complexity of the types of organizations that comprise a modern supply chain, the problems that arise as a result of this complexity, and the solutions and analytical approaches available to managers that can help resolve these real world problems and dilemmas. The modern enterprise, be it a large corporation or a government agency, has two key dimensions of complexity: static and dynamic. The static complexity refers to the remarkable number of companies and agencies that enable delivery of the product or service. A static "snapshot" of this end-to-end enterprise would reveal hundreds if not thousands of companies involved in the supply network and many additional firms involved in the distribution and delivery to customers. Planning, communication, coordination and execution of this large system network is fundamentally challenging just because of the sheer size. This large, extended network represents the static complexity. The dynamic complexity arises from the difficulty of managing the performance of this extended enterprise over time. This requires having the appropriate metrics to track performance over time, the management skills to develop strategies, the ability to collect and monitor the correct data for true visibility, and the recognition and understanding of the long lags between actions and results. Design, Analysis and Optimization of Supply Chains: A System Dynamic Approach incorporates real-world examples and cases, representing actual complex enterprise systems including firms involved and with long lead times, to illustrate the multi-faceted activities occurring within a modern supply chain and the challenges they pose to managers. Simulation and optimization techniques are introduced and used to develop strategies for improved performance.
Reason, Faith, and Purpose: The Ultimate Gamble is a guide for believers and inquiring skeptics. This book summarizes the scientific view of the origins of the universe and life and analyzes the question of the existence of god from philosophical, religious, and scientific perspectives.The material is presented in two parts. Part I presents the secular, scientific view of the origin and evolution of the physical universe and life. Part II introduces other perspectives that are representative of ideas historically prevalent around the world. The material in Reason, Faith, and Purpose is designed to provide insight into the choice each of us must make in this life: the ultimate gamble.
Presents Performance And Policy Analysis Of Indian Transport Sector-An Overview Of General Aspects Of Transport Sectors-Performance Of-Railways, Roads, Airways And Water Ways And The Latest Trends In Energy Consuption And Environmental Emissions. Divided Into 3 Parts And Has 12 Chapters And 2 Appendices.
Radio systems capable of localization have emerging applications in homeland security, law enforcement, emergency response, defense command and control, multi-robot coordination and vehicle-to-vehicle and vehicle-to-pedestrian collision avoidance. In fact, high resolution localization is vital for many applications, including: traffic alert, emergency services, e.g., indoor localization for firefighters, and battlefield command and control. These systems promise to dramatically reduce society's vulnerabilities to catastrophic events and improve its quality of of life. While work this important area is progressing, limited resources are available to support graduate students and researchers in this important area. Specifically, a limited number of books has been published in this area covering selected subjects. This comprehensive handbook offers gaps of available localization books presenting in-depth coverage from fundamentals of coordinates to advanced application examples.
Designed to address all aspects of shoulder reconstruction, this volume in the Disorders of the Shoulder series provides complete and practical discussions of the reconstructive process—from diagnosis and planning, through surgical and nonsurgical treatments, to outcome and return to functionality.
An invaluable source of inspiration to help leaders understand themselves and overcome their barriers to success For centuries, we have learnt what’s not taught through our own experiences and the stories of others. Even today, only 3 per cent of leadership development occurs due to classroom training. In fact, for most managers, ‘the penny drops’ only when we are at the end of our careers. In this book, R. Gopalakrishnan shares some valuable learnings from his decades of corporate experience, through a series of engaging stories. When the Penny Drops encourages you to reflect on yourself, and will help you learn by identifying the success mantras embedded in you.
The second edition of this popular textbook presents a balanced overview of the principles of supply chain management. Going beyond the usual supply chain text, Principles of Supply Chain Management not only details the individual components of the supply chain, but also illustrates how the pieces must come together. To show the logic behind why supply chain management is essential, the text examines how supply chains are evolving, looks ahead to new developments, and provides a balanced look at supply chains with a focus on both the customer side and the supplier side of supply chains. See What’s New in the Second Edition: Expanded coverage of current topics such as e-commerce, risk management, outsourcing and reshoring, sustainability, project management, and data analytics Increased emphasis on how customers are becoming more influential in steering product design Additional coverage of the use of data analytics to evaluate customer preferences and buying patterns A new chapter devoted to logistics and its increasing importance in supply chains Company profiles of organizations with effective supply chains that illustrate the main theme of each chapter A "Hot Topic" for each chapter, providing a description of a critical management issue to stimulate class discussion A complete set of instructor materials for each chapter, including presentation slides, test banks, class exercises, discussion questions, and more From the point of distribution to the final customer, all the way back to the point of origin at the mine or farm, the text provides examples and case histories that illustrate a proven approach for achieving effective supply chain integration. This self-contained resource provides readers with a realistic appraisal of the state of the art in supply chain management and the understanding needed to build and manage effective supply chains in a wide range of industries. Most importantly, it emphasizes the need for building and maintaining collaboration among all members of the supply chain.
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
This monograph presents for the first time the foundations of Hamilton Geometry. The concept of Hamilton Space, introduced by the first author and investigated by the authors, opens a new domain in differential geometry with large applications in mechanics, physics, optimal control, etc. The book consists of thirteen chapters. The first three chapters present the topics of the tangent bundle geometry, Finsler and Lagrange spaces. Chapters 4-7 are devoted to the construction of geometry of Hamilton spaces and the duality between these spaces and Lagrange spaces. The dual of a Finsler space is a Cartan space. Even this notion is completely new, its geometry has the same symmetry and beauty as that of Finsler spaces. Chapter 8 deals with symplectic transformations of cotangent bundle. The last five chapters present, for the first time, the geometrical theory and applications of Higher-Order Hamilton spaces. In particular, the case of order two is presented in detail. Audience: mathematicians, geometers, physicists, and mechanicians. This volume can also be recommended as a supplementary graduate text.
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