Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible cell has been described by GOWANS (1965) as a small lymphocyte. Passive transfer has also been achieved in the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo characteristic of delayed hypersensitivity from which the class derives its name is the delayed skin reaction. When an antigen is injected intradermally into a previously immunized animal, the typical delayed reaction begins to appear after 4 hours, reaches a peak at 24 hours, and fades after 48 hours. It is grossly characterized by induration, erythyma, and occasionally necrosis. The histology of the delayed reaction has been studied by numerous investigators (COHEN et al., 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al., 1963; MCCLUSKEY et al., 1963; WAKSMAN, 1960; WAKSMAN, 1962). Initially dilatation of the capillaries with exudation of fluid and cells occurs.
This volume is the first comprehensive history of task analysis, charting its origins from the earliest applied psychology through to modern forms of task analysis that focus on the study of cognitive work. Through this detailed historical analysis, it is made apparent how task analysis has always been cognitive.Chapters cover the histori
While, not discounting the potency of the radical Islamic religious discourse in fuelling the contemporary wave of terrorism, this book makes an attempt to explain terrorism in China as an ethno-nationalist conflict rooted in issues involving minority identity. However, a largely domestic conflict is being hijacked by the radical Islamists.
This timely reference provides the latest information on the diagnosis, treatment, and prevention of nosocomial pneumonia, including risk factors, diagnostic tests used to make the definitive diagnosis, likely pathogens, and the most effective treatment options. Contains guidelines for the prevention of nosocomial pneumonia-emphasizing selected
During the Civil War, Vicksburg, Mississippi, assumed almost mythic importance in the minds of Americans: northerners and southerners, soldier and civilian. The city occupied a strategic and commanding position atop rocky cliffs above the Mississippi River, from which it controlled the great waterway. As a result, Federal forces expended enormous effort, expense, and troops in many attempts to capture Vicksburg. The immense struggle for this southern bastion ultimately heightened its importance beyond its physical and strategic value. Its psychological significance elevated the town’s status to one of the war’s most important locations. Vicksburg’s defiance dismayed northerners and delighted Confederates, who saw command of the river as a badge of honor. Finally, after a six-week siege that involved intense military and civilian suffering amid heavy artillery bombardment, Union forces captured the “Gibraltar of the Confederacy,” ending the bloody campaign. While many historians have told the story of the fall of Vicksburg, Bradley R. Clampitt is the first to offer a comprehensive examination of life there after its capture by the United States military. In the war-ravaged town, indiscriminate hardships befell soldiers and civilians alike during the last two years of the conflict and immediately after its end. In Occupied Vicksburg, Clampitt shows that following the Confederate withdrawal, Federal forces confronted myriad challenges in the city including filth, disease, and a never-ending stream of black and white refugees. Union leaders also responded to the pressures of newly free people and persistent guerrilla violence in the surrounding countryside. Detailing the trials of blacks, whites, northerners, and southerners, Occupied Vicksburg stands as a significant contribution to Civil War studies, adding to our understanding of military events and the home front. Clampitt’s astute research provides insight into the very nature of the war and enhances existing scholarship on the experiences of common people during America’s most cataclysmic event.
This book provides a balanced discussion about the wastewater generated by hydraulic fracturing operations, and how to manage it. It includes an in-depth discussion of the hydraulic fracturing process, the resulting water cycle, and the potential risks to groundwater, soil, and air. The “fracking” process involves numerous chemicals that could potentially harm human health and the environment, especially if they enter and contaminate drinking water supplies. Treatment, reuse, and disposal options are the focus, and several case studies will be presented. The book also discusses the issues of the large amounts of water required for drilling operations, the impacts on water-sensitive regions.
Examines trends in the mathematics scores of different racial-ethnic groups over time and analyzes how changes in family, school, and schooling measures help explain changes in the test score gaps. Although there were few positive changes between schools, the within-school experiences of black and Latino students changed for the better compared with white students when measured by student self-reported academic track placement.
A major transformation in research and training is expected, using new, more advanced versions of computer-based systems. Technology now affords new capabilities: complex and distributed expert decisionmaking and team performance can now be elicited and rehearsed through affordable and easily distributed systems. These new systems will transform research and training on two fronts. It will allow research needed to bridge the gap between internal (i.e. laboratory control) and external (e.g. operational relevance) validity. In addition, it enables a coalition of forces, from training instructors and their students, to research scientists and quantitative performance modelers. While simulation-based research and training is rapidly advancing, with increased funding and sponsorship, as yet there is no comprehensive documentation of tools and techniques. This book addresses the problem, bringing together experts from a variety of perspectives. Their contributions document emerging trends and issues with regard to development, utilization, and validation of these emerging ’scaled world’ systems. The readership includes researchers and practitioners who develop and/or utilize simulation-based environments, educators interested in instructional technology and researchers who require criterion-based performance evaluation.
Successful social marketing holds the power to change the world. For almost two decades, Social Marketing: Behavior Change for Social Good has been the definitive guide for designing and implementing memorable social marketing campaigns. Bestselling authors Nancy R. Lee and Philip Kotler present a proven 10 Step Strategic Social Marketing Planning Model and guides students and practitioners through each stage of the process. The new Sixth Edition is packed with more than 25 new cases and dozens of new examples related to today's most pressing social problems including the opioid epidemic, climate change, youth suicide, and more. The new edition also includes significantly expanded coverage of social media. Whether you are on a mission to improve public health, protect the environment, or galvanize their community, you will find Social Marketing an invaluable resource.
This book analyzes the relations between two geographical areas with different levels of regional institutionalization: the European Union and Latin America. Characterized by low interdependence and asymmetry, this relationship operates in different levels ranging from EU-individual countries to EU-Latin American summits.
Ecosystem-based fishery management (EBFM) is rapidly becoming the default approach in global fisheries management. The clarity of what EBFM means is sharpening each year and there is now a real need to evaluate progress and assess the effectiveness and impacts. By examining a suite of over 90 indicators (including socioeconomic, governance, environmental forcing, major pressures, systems ecology, and fisheries criteria) for 9 major US fishery ecosystem jurisdictions, the authors systematically track the progress the country has made towards advancing EBFM and making it an operational reality. The assessment covers a wide range of data in both time (multiple decades) and space (from the tropics to the poles, representing over 10% of the world's ocean surface area). The authors view progress towards the implementation of EBFM as synonymous with improved management of living marine resources in general, and highlight the findings from a national perspective. Although US-centric, the lessons learned are directly applicable for all parts of the global ocean. Much work remains, but significant progress has already been made to better address many of the challenges facing the sustainable management of our living marine resources. This is an essential and accessible reference for all fisheries professionals who are currently practicing, or progressing towards, ecosystem-based fisheries management. It will also be of relevance and use to researchers, teachers, managers, and graduate students in marine ecology, fisheries biology, biological oceanography, global change biology, conservation biology, and marine resource management.
Compiles the most current information on the Zika virus and its associated diseases This comprehensive book provides the most up-to-date information for students, medical students, and scientists on Zika virus and its associated diseases. It includes all the information related to the Zika virus since its discovery in 1947; its epidemic outbreak in 2007-2014; how the epidemiology changed in America in 2015-2016; its mode of transmission; how to prevent and treat it; and associated diseases. Zika Virus and Diseases: From Molecular Biology to Epidemiology offers complete and up-to-date coverage in 10 chapters. It presents information from papers that attempted to associate the virus with diseases in Africa until the first animal experiment; discusses its association with Guillain-Barré syndrome and microcephaly; describes the basic mechanisms for Zika (ZIKV) replication, including important differences between Dengue (DENV), West-Nile virus (WNV), and ZIKV; explains the difference between the strains and discusses the pathogenesis of them; covers the papers that showed all the interferences that Zika can cause, and the pathways which can be modified; and more. The first book since 1947 to put together all the scientific information Compiles all the information received in the last year about Zika virus Clearly demonstrates the origin and discovery of the virus Zika Virus and Diseases: From Molecular Biology to Epidemiology will appeal to graduate students, medical students, basic researchers, clinicians in infectious disease, microbiology, and virology, as well as people in related disciplines interested in learning more about this topic.
This biographical dictionary of some 3,000 photographers (and workers in related trades), active in a vast area of North America before 1866, is based on extensive research and enhanced by some 240 illustrations, most of which are published here for the first time. The territory covered extends from central Canada through Mexico and includes the United States from the Mississippi River west to, but not including, the Rocky Mountain states. Together, this volume and its predecessor, Pioneer Photographers of the Far West: A Biographical Dictionary, 1840-1865, comprise an exhaustive survey of early photographers in North America and Central America, excluding the eastern United States and eastern Canada. This work is distinguished by the large number of entries, by the appealing narratives that cover both professional and private lives of the subjects, and by the painstaking documentation. It will be an essential reference work for historians, libraries, and museums, as well as for collectors of and dealers in early American photography. In addition to photographers, the book includes photographic printers, retouchers, and colorists, and manufacturers and sellers of photographic apparatus and stock. Because creators of moving panoramas and optical amusements such as dioramas and magic lantern performances often fashioned their works after photographs, the people behind those exhibitions are also discussed.
This pioneering work brings together for the first time in a single reference work all of the extant, fugitive, and recently discovered registration data on African American voters from Colonial America to the present. It features election returns for African American presidential, senatorial, congressional, and gubernatorial candidates over time. Rich, insightful narrative explains the data and traces the history of the laws dealing with the enfranchisement and disenfranchisement of African Americans. Topics covered include: - The contributions of statistical pioneers including Monroe Work, W.E.B. DuBois and Ralph Bunche - African American organizations, like the NAACP and National Equal Rights League (NERL) - Pioneering African American officeholders, including the few before the Civil War - Four influxes of African American voters: Reconstruction (Southern African American men), the Fifteenth Amendment (African American men across the country), the Nineteenth Amendment (African American female voters in 1920 election), and the Voting Rights Act of 1965 - The historical development of disenfranchisement in the South and the statistical impact of the tools of disenfranchisement: literacy clauses, poll taxes, and grandfather clauses. The African-American Electorate features more than 300 tables, 150 figures, and 50 maps, many of which have been created exclusively for this work using demographic, voter registration, election return, and racial precinct data that have never been collected and assembled for the public. An appendix includes popular and electoral voting data for African-American presidential, congressional, and gubernatorial candidates, and a comprehensive bibliography indicates major topic areas and eras concerning the African-American electorate. The African American Electorate offers students and researchers the opportunity, for the first time, to explore the relationship between voters and political candidates, identify critical variables, and situate African Americans' voting behavior and political phenomena in the context of America's political history.
In this book, we identify key areas for Mississippi economic policy reform. Twenty-one scholars, ten of which are from or work in Mississippi, have contributed original policy research. All twenty chapters were written specifically for Mississippi with a shared goal to promote prosperity in the state. While some of the chapters contain complex policy reforms, we have made every effort to present the concepts and ideas in a way that is understandable to the average citizen, the person who can benefit the most from this information. The first three chapters of the text summarize the basic economic principles necessary to achieve economic prosperity. These three chapters present the principles behind the reforms proposed in the subsequent seventeen chapters. Each chapter was written independently and offers unique insight into different areas of state policy reform. While the topics covered range from tax reform, education reform, healthcare, corporate welfare, occupational licensing and business regulatory reform to criminal justice reform, and natural disaster recovery efforts, there is a clear unifying framework underlying the conclusions reached in each chapter. The theme throughout is that economic growth is best achieved through free market policies, policies which are based on limited government, lower regulations, lower taxes, minimal infringement on contracting and labor markets, secure private property rights, low subsidies, and privatization. Policy based on these principles allows Mississippians to have more rights and more choices in their lives.
This book focuses on the economic decisions that must be made in the household. It states that domestic activities are commonly grouped into two primary types, one having to do with social reproduction, the other with the production and consumption of foods.
In Teaching for Spiritual Formation, church historian and experienced Christian educator Kyle R. Hughes advances a fresh vision of Christian teaching and learning by drawing upon the riches of the Christian tradition, synthesizing the wisdom of the early church fathers with contemporary efforts to cultivate a distinctively Christian approach to education. Of interest to a wide range of Christian educators, this book examines how the writings of five significant church fathers can illuminate our understanding of the vocation of teachers, the nature of students, the purpose of curriculum, decisions about pedagogy, and how spiritual formation works. Besides reimagining these aspects of Christian education, Hughes also offers habits and practices that can help bring this vision of Christian teaching and learning to life, challenging Christian educators to sharpen their approach to the integration of faith and learning in practical and accessible ways.
This book covers suggested clauses for both inter vivos and testamentary instruments and examines court reactions to a petition for change when the trust instrument does not specifically give one.
Part of a series of detailed reference manuals on American economic history, this volume traces the development and rapid growth of transportation across the USA in the mid-1800s.
Why would a country strongly influenced by Buddhism's reverence for life allow legalized, widely used abortion? Equally puzzling to many Westerners is the Japanese practice of mizuko rites, in which the parents of aborted fetuses pray for the well-being of these rejected "lives." In this provocative investigation, William LaFleur examines abortion as a window on the culture and ethics of Japan. At the same time he contributes to the Western debate on abortion, exploring how the Japanese resolve their conflicting emotions privately and avoid the pro-life/pro-choice politics that sharply divide Americans on the issue.
Entity Information Life Cycle for Big Data walks you through the ins and outs of managing entity information so you can successfully achieve master data management (MDM) in the era of big data. This book explains big data's impact on MDM and the critical role of entity information management system (EIMS) in successful MDM. Expert authors Dr. John R. Talburt and Dr. Yinle Zhou provide a thorough background in the principles of managing the entity information life cycle and provide practical tips and techniques for implementing an EIMS, strategies for exploiting distributed processing to handle big data for EIMS, and examples from real applications. Additional material on the theory of EIIM and methods for assessing and evaluating EIMS performance also make this book appropriate for use as a textbook in courses on entity and identity management, data management, customer relationship management (CRM), and related topics. - Explains the business value and impact of entity information management system (EIMS) and directly addresses the problem of EIMS design and operation, a critical issue organizations face when implementing MDM systems - Offers practical guidance to help you design and build an EIM system that will successfully handle big data - Details how to measure and evaluate entity integrity in MDM systems and explains the principles and processes that comprise EIM - Provides an understanding of features and functions an EIM system should have that will assist in evaluating commercial EIM systems - Includes chapter review questions, exercises, tips, and free downloads of demonstrations that use the OYSTER open source EIM system - Executable code (Java .jar files), control scripts, and synthetic input data illustrate various aspects of CSRUD life cycle such as identity capture, identity update, and assertions
Written by authors with extensive experience in the field and in the classroom, Introduction to Forensic Psychology: Research and Application, Sixth Edition demonstrates how to analyze psychological knowledge and research findings and apply these findings to the civil and criminal justice systems. Focusing on research-based forensic practice and practical application, the authors use real-life examples and case law discussions to define and explore forensic psychology. Students are introduced to emerging specializations within forensic psychology, including investigative psychology, family forensic psychology, and police and public safety psychology. Research related to bias, diversity, and discrimination is included throughout the text to give students a multicultural perspective that is critical to the successful practice of forensic psychology. Included with this title: Instructor Online Resources: Access online resources for this title via the password-protected Instructor Resource Site. Learn More
At 8:43 a.m. on the morning of Sunday, October 6, 1918, HMS Kashmir rammed HMS Otranto off Islay, Scotland. Both ships were former British passenger liners from the P&O Steamship Company that had been pulled into the war to ferry American soldiers between New York and various British ports. On this stormy morning, however, they were part of Convoy HX-50 carrying troops to Liverpool. On board were 372 British officers and sailors and 701 American soldiers. The Americans were mostly Southern farm boys from Fort Screven in Savannah under the command of Lt. Sam Levy, a Georgia Tech graduate from Atlanta. The Kashmir managed to back away and follow the harsh wartime order that required her to ignore any maritime disasters that might befall her sister ships and to continue on her prescribed course rather than stop and take on survivors. Thus it was that—with winds blowing at 70 to 75 mph and waves at more than 60 feet—the severely damaged Otranto was left dead in the water with more than a thousand souls aboard. Many Were Held by the Sea: The Tragic Sinking of HMS Otranto, tells the story of what happened during that voyage—mostly from the perspective of the American soldiers—and builds to the disastrous conclusion. The narrative details the courage of the young men on board, men who, for the most part, had never seen the ocean or learned to swim. It tells of the anguish from the home front, as family members had to wait weeks to learn the fate of their relatives. In addition, Scott’s narrative tells the personal story of Lieutenant Craven of the Royal Navy, serving as Commander of the rescue ship, who was forced to gamble with the lives of those on both ships in order to save the maximum number of passengers.
This volume presents the story of the Eastern Band of Cherokees during the nineteenth century. This group - the tribal remnant in North Carolina that escaped removal in the 1830's - found their fortitude and resilience continually tested as they struggled with a variety of problems, including the upheavals of the Civil War and Reconstruction, internal divisiveness, white encroachment on their lands, and a poorly defined relationship with the state and federal governments. Yet despite such stresses and a selective adaptation in the face of social and economic changes, the Eastern Cherokees retained a sense of tribal identity as they stood at the threshold of the twentieth century.
- Thoroughly revised and expanded to reflect the substantial changes in the field since its publication in 1978 - Strong emphasis on how to effectively use software design packages, indispensable to today's lens designer - Many new lens design problems and examples – ranging from simple lenses to complex zoom lenses and mirror systems – give insight for both the newcomer and specialist in the field Rudolf Kingslake is regarded as the American father of lens design; his book, not revised since its publication in 1978, is viewed as a classic in the field. Naturally, the area has developed considerably since the book was published, the most obvious changes being the availability of powerful lens design software packages, theoretical advances, and new surface fabrication technologies. This book provides the skills and knowledge to move into the exciting world of contemporary lens design and develop practical lenses needed for the great variety of 21st-century applications. Continuing to focus on fundamental methods and procedures of lens design, this revision by R. Barry Johnson of a classic modernizes symbology and nomenclature, improves conceptual clarity, broadens the study of aberrations, enhances discussion of multi-mirror systems, adds tilted and decentered systems with eccentric pupils, explores use of aberrations in the optimization process, enlarges field flattener concepts, expands discussion of image analysis, includes many new exemplary examples to illustrate concepts, and much more. Optical engineers working in lens design will find this book an invaluable guide to lens design in traditional and emerging areas of application; it is also suited to advanced undergraduate or graduate course in lens design principles and as a self-learning tutorial and reference for the practitioner. Rudolf Kingslake (1903-2003) was a founding faculty member of the Institute of Optics at The University of Rochester (1929) and remained teaching until 1983. Concurrently, in 1937 he became head of the lens design department at Eastman Kodak until his retirement in 1969. Dr. Kingslake published numerous papers, books, and was awarded many patents. He was a Fellow of SPIE and OSA, and an OSA President (1947-48). He was awarded the Progress Medal from SMPTE (1978), the Frederic Ives Medal (1973), and the Gold Medal of SPIE (1980). R. Barry Johnson has been involved for over 40 years in lens design, optical systems design, and electro-optical systems engineering. He has been a faculty member at three academic institutions engaged in optics education and research, co-founder of the Center for Applied Optics at the University of Alabama in Huntsville, employed by a number of companies, and provided consulting services. Dr. Johnson is an SPIE Fellow and Life Member, OSA Fellow, and an SPIE President (1987). He published numerous papers and has been awarded many patents. Dr. Johnson was founder and Chairman of the SPIE Lens Design Working Group (1988-2002), is an active Program Committee member of the International Optical Design Conference, and perennial co-chair of the annual SPIE Current Developments in Lens Design and Optical Engineering Conference. - Thoroughly revised and expanded to reflect the substantial changes in the field since its publication in 1978 - Strong emphasis on how to effectively use software design packages, indispensable to today's lens designer - Many new lens design problems and examples – ranging from simple lenses to complex zoom lenses and mirror systems – give insight for both the newcomer and specialist in the field
Sams Teach Yourself SQL in 21 Days, Fourth Editionprovides a sold foundation in understanding the fundamentals of SQL (Structured Query Language). SQL is the query language used by relational databases such a Oracle, Microsoft Access, and Microsoft SQL Server. The new edition covers object-oriented programming with SQL, ODBC, JDBC, embedded SQL, accessing remote databases, and constructs. All new examples based on an open source database such as MySQL enhance this new edition by making the examples readily useable for readers.
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found
Because they were situated near the Mason-Dixon line, Shepherdstown residents witnessed the realities of the Civil War firsthand. Marching armies, sounds of battle and fear of war had arrived on their doorsteps by the summer of 1862. The Maryland Campaign of September 1862 brought thousands of wounded Confederates into the town's homes, churches and warehouses. The story of Shepherdstown's transformation into "one vast hospital" recounts nightmarish scenes of Confederate soldiers under the caring hands of an army of surgeons and civilians. Author Kevin R. Pawlak retraces the horrific accounts of Shepherdstown as a Civil War hospital town.
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