In this text, the small team of expert authors presents the field in a comprehensive and accessible manner that is well suited for students and junior researchers. The result is a highly readable and systematically structured introduction to antimicrobial peptides, their structure, biological function and mode of action. The authors point the way towards a rational design of this potentially highly effective new class of clinical antibiotics on the brink of industrial application. They do this by discussing their design principles, target membranes and structure-activity relationships. The final part of the book describes recent successes in the application of peptides as anticancer agents.
Discusses the Legal aspects of launching and operating different Satellite systems: Direct Broadcasting System, Remote Sensing, and Military; also general responsibility and liability principles.
Bald nach Erscheinen des Bandes "Geschwülste" "Geschwiilste" 1956 1956 wurde wurde deutlich, deutlich, daß daB dies dies nur ein Anfang gewesen sein konnte. Die grundlegenden Beitrage Beiträge dieses Bandes spiegelten den Wissensstand am Beginn des 6. Jahrzehnts wider. Sie waren wahrscheinlich zugleich die letzten echten Handbuchbeitrage Handbuchbeiträge zu diesem Thema: umfassend und enzyklopadisch enzyklopädisch vollständig vollstandig und trotzdem als Ganzes lesbar, verfaßt verfaBt von den damals besten Sachkennern in Deutschland. Inzwischen hat sich das Handbuch der Allgemeinen Pathologie gewandelt. Entsprechend der Weitung des Faches vergrößerten vergroBerten sich die Themen. Neben den Bänden Banden tiber über die die Organe Organe zum zum Hilfsmechanismus Hilfsmechanismus des des Stoffwechsels, Stoffwechsels, tiber über die die Zelle, Zelle, das das Altern Altern usw. usw. nahm sich der Geschwulstband vergleichsweise bescheiden aus. Das steht im Gegensatz zur Stellung des Geschwulstproblems in der Allgemeinen Pathologie. Die Krebsforschung erfuhr gerade in den letzten beiden Jahrzehnten einen vorher nicht geahnten Aufschwung, so daß daB eine eine enzyklopädische enzyklopadische Zusammenfassung Zusammenfassung heute heute den den Umfang Umfang des des gesamten gesamten Handbuches Handbuches einnehmen einnehmen würde wtirde -- wenn wenn sich sich jemand fände, rande, das das zu zu versuchen. versuchen. Und wenn der letzte Band gedruckt wäre, ware, ware wäre der erste hoffnungslos veraltet.
Remote Sensing Applications in Environmental and Earth System Sciences is a contemporary, multi-disciplinary, multi-scaling, updated, and upgraded approach of applied remote sensing in the environment. The book begins with an overview of remote sensing technology, and then explains the types of data that can be used as well as the image processing and analysis methods that can be applied to each type of application through the use of case studies throughout. Includes a wide spectrum of environmental applications and issues Explains methodological image analysis and interpretation procedures for conducting a variety of environmental analyses Discusses the development of early warning systems Covers monitoring of the environment as a whole – atmosphere, land, and water Explores the latest remote sensing systems in environmental applications This book is an excellent resource for anyone who is interested in remote sensing technologies and their use in Earth systems, natural resources, and environmental science.
Explore the Radiative Exchange between Surfaces Further expanding on the changes made to the fifth edition, Thermal Radiation Heat Transfer, 6th Edition continues to highlight the relevance of thermal radiative transfer and focus on concepts that develop the radiative transfer equation (RTE). The book explains the fundamentals of radiative transfer, introduces the energy and radiative transfer equations, covers a variety of approaches used to gauge radiative heat exchange between different surfaces and structures, and provides solution techniques for solving the RTE. What’s New in the Sixth Edition This revised version updates information on properties of surfaces and of absorbing/emitting/scattering materials, radiative transfer among surfaces, and radiative transfer in participating media. It also enhances the chapter on near-field effects, addresses new applications that include enhanced solar cell performance and self-regulating surfaces for thermal control, and updates references. Comprised of 17 chapters, this text: Discusses the fundamental RTE and its simplified forms for different medium properties Presents an intuitive relationship between the RTE formulations and the configuration factor analyses Explores the historical development and the radiative behavior of a blackbody Defines the radiative properties of solid opaque surfaces Provides a detailed analysis and solution procedure for radiation exchange analysis Contains methods for determining the radiative flux divergence (the radiative source term in the energy equation) Thermal Radiation Heat Transfer, 6th Edition explores methods for solving the RTE to determine the local spectral intensity, radiative flux, and flux gradient. This book enables you to assess and calculate the exchange of energy between objects that determine radiative transfer at different energy levels.
Barley: Chemistry and Technology, Second Edition is an important resource for any cereal chemist, food scientist, or crop scientist who needs to understand the development, structure, composition, and end-use properties of the barley grain for cultivation, trade, and utilization. Editors Peter R. Shewry and Steven E. Ullrich bring together a wide range of international authorities on barley to create this truly unique, encyclopedic reference work that covers the massive increase in barley knowledge over the past 20 years, since the first edition of this book was published. Barley: Chemistry and Technology, Second Edition offers the latest coverage of barley’s applications in milling, breeding, and production for food, feed, malting, brewing, distilling, and biofuels. It delivers a complete update of the latest knowledge of barley’s many components, from the genetic and molecular level to its many constituents, such as proteins, carbohydrates, arabinoxylans, minerals, lipids, terpenoids, phenolics, and vitamins. This important book also includes chapters on barley’s plant and grain development from both the physiological and genetic perspectives, making it an important resource not only for cereal and food scientists but also for crop scientists involved in breeding, agronomy, and related plant sciences New coverage includes: Updated, comprehensive knowledge on barley’s components, including proteins, carbohydrates, arabinoxylans, and bioactive effects New end-use ideas for barley as an ingredient in food products Nonfood industrial applications for barley, including biofuels A new chapter on barley’s health benefits Molecular breeding for malting quality
Phenomena as diverse as tuberculin sensitivity, delayed sensitivity to soluble proteins other than tuberculin, contact allergy, homograft rejection, experimental autoallergies, and the response to many microorganisms, have been classified as members of the class of immune reactions known as delayed or cellular hypersensitivity. Similarities in time course, histology, and absence of detectable circulating immunoglobulins characterize these cell-mediated immune reactions in vivo. The state of delayed or cellular hypersensitivity can be transferred from one animal to another by means of sensitized living lymphoid cells (CHASE, 1945; LANDSTEINER and CHASE, 1942; MITCHISON, 1954). The responsible cell has been described by GOWANS (1965) as a small lymphocyte. Passive transfer has also been achieved in the human with extracts of sensitized cells (LAWRENCE, 1959). The in vivo characteristic of delayed hypersensitivity from which the class derives its name is the delayed skin reaction. When an antigen is injected intradermally into a previously immunized animal, the typical delayed reaction begins to appear after 4 hours, reaches a peak at 24 hours, and fades after 48 hours. It is grossly characterized by induration, erythyma, and occasionally necrosis. The histology of the delayed reaction has been studied by numerous investigators (COHEN et al., 1967; GELL and HINDE, 1951; KOSUNEN, 1966; KOSUNEN et al., 1963; MCCLUSKEY et al., 1963; WAKSMAN, 1960; WAKSMAN, 1962). Initially dilatation of the capillaries with exudation of fluid and cells occurs.
VOllS n'avez donne aucune des explications metaphysiques qui otent au mystere de I'Eucharistie ses apparentes im possibilites. Ce ne sont, il est vrai, que des hypotheses et c'est deja beaucoup que de concevoir un ensemble de rap ports qui eclaircit certaines difficultes des choses sans etre contredit par aucune loi de la nature et du raisonnement. Lettre du P. Lacordaire II Auguste Nicolas, dans A. Nicolas, Etudes Philosophiques, t. I, P. V, de laseme edition (I847). Specimen Theologiae: les pages qui suivent ne sont guere qu'un echan tillon, un essai, d'histoire de la theologie post-tridentine. La theologie moderne est ici saisie a son premier age, contemporaine de ces trois remises en cause fondamentales que sont la Reforme, Ie cartesianisme et la renaissance spirituelle du catholicisme. Trois tentatives de renou veler la vision du monde re.
Originally published in 1981, this third volume deals with the empirical data base and the theories concerning visual perception – the set of mental responses to photic stimulation of the eyes. As the book develops, the plan was to present a general taxonomy of visual processes and phenomena. It was hoped that such a general perspective would help to bring some order to the extensive, but largely unorganized, research literature dealing with our immediate perceptual responses to visual stimuli at the time. The specific goal of this work was to provide a classification system that integrates and systematizes the data base of perceptual psychology into a comprehensive intellectual scheme by means of an eclectic, multi-level metatheory invoking several different kinds of explanation.
From Roentgen to Rembrandt, Hounsfield to Hollywood and Vesalius to videogames, Imagining Imaging explores the deeply entwined relationship between art (and visual-based culture) and radiology / medical imaging. Including artworks from numerous historical eras representing varied geographic locations and visual traditions, alongside a diverse range of contemporary artists, Dr Jackson argues that the foundations of medical image construction and interpretation were laid down in artistic innovations dating back hundreds and thousands of years. Since the discovery of X-rays, artists and moviemakers have, in turn, drawn rich inspiration from radiographic imagery and concepts, but the process of cross-pollination between art and science has continued, with creative endeavour continuing to mould medical imaging examinations to this day. Blending a unique mix of art, science and medical history, together with aspects of visual neurophysiology and psychology, Imagining Imaging is essential reading for radiologists, radiographers and artists alike. Peppered with familiar TV and film references, personal insights into the business of image interpretation, and delivered in an accessible and humorous style, the book will also appeal to anyone who enjoys looking at pictures. Key features: Engaging synthesis of art and medical history, combined with anecdotes and experiences from a working clinical radiologist Diverse range of visual reference points including astronomy, botany and cartography, alongside comprehensive discussion of medical imaging modalities including plain radiography, ultrasound, CT and MRI 200 full colour illustrations
Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You'll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors-such as heavy metals and pesticides-and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. And, Expert Consult functionality allows you to access the full text of the book online, from any Internet connection. Provides a complete listing of neurotoxic agents-from manufactured to environmental-so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson's Disease, motor neuron disease, as well as other issues that are still in question. Includes access to www.expertconsult.com, a companion website where you can quickly search the complete contents of the book. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.
Brought together for the first time in a single volume, these eight important and fascinating essays by Nobel Prize-winning psychiatrist Eric Kandel provide a breakthrough perspective on how biology has influenced modern psychiatric thought. Complete with commentaries by experts in the field, Psychiatry, Psychoanalysis, and the New Biology of Mind reflects the author's evolving view of how biology has revolutionized psychiatry and psychology and how potentially could alter modern psychoanalytic thought. The author's unique perspective on both psychoanalysis and biological research has led to breakthroughs in our thinking about neurobiology, psychiatry, and psychoanalysis -- all driven by the central idea that a fuller understanding of the biological processes of learning and memory can illuminate our understanding of behavior and its disorders. These wonderful essays cover the mechanisms of psychotherapy and medications, showing that both work at the same level of neural circuits and synapses, and the implications of neurobiological research for psychotherapy; the ability to detect functional changes in the brain after psychotherapy, which enables us, for the first time, to objectively evaluate the effects of psychotherapy on individual patients; the need for animal models of mental disorders; for example, learned fear, to show how molecules and cellular mechanisms for learning and memory can be combined in various ways to produce a range of adaptive and maladaptive behaviors; the unification of behavioral psychology, cognitive psychology, neuroscience, and molecular biology into the new science of the mind, charted in two seminal reports on neurobiology and molecular biology given in 1983 and 2000; the critical role of synapses and synaptic strength in both short- and long-term learning; the biological and social implications of the mapping of the human genome for medicine in general and for psychiatry and mental health in particular; The author concludes by calling for a revolution in psychiatry, one that can use the power of biology and cognitive psychology to treat the many mentally ill persons who do not benefit from drug therapy. Fascinating reading for psychiatrists, psychoanalysts, social workers, residents in psychiatry, and trainees in psychoanalysis, Psychiatry, Psychoanalysis, and the New Biology of Mind records with elegant precision the monumental changes taking place in psychiatric thinking. It is an invaluable reference work and a treasured resource for thinking about the future.
This book gives a comprehensive account of the history and underlying economics of the modern art market in eighteenth- and nineteenth-century Britain.
Essentials of Cognitive Neuroscience introduces and explicates key principles and concepts in cognitive neuroscience in such a way that the reader will be equipped to critically evaluate the ever-growing body of findings that the field is generating. For some students this knowledge will be needed for subsequent formal study, and for all readers it will be needed to evaluate and interpret reports about cognitive neuroscience research that make their way daily into the news media and popular culture. The book seeks to do so in a style that will give the student a sense of what it's like to be a cognitive neuroscientist: when confronted with a problem, how does one proceed? How does one read and interpret research that's outside of one's sub-area of specialization? How do two scientists advancing mutually incompatible models interrelate? Most importantly, what does it feel like to partake in the wonder and excitement of this most dynamic and fundamental of sciences?
This unique reference article, excerpted from the larger work (Dictionary of Daily Life in Biblical and Post-Biblical Antiquity), provides background cultural and technical information on the world of the Hebrew Bible and New Testament from 2000 BC to approximately AD 600. Written and edited by a world-class historian and a highly respected biblical scholar, each article addresses cultural, technical, and/or sociological issues of interest to the study of the Scriptures. Contains a high level of scholarship.Information and concepts are explained in detail and are accompanied by bibliographic material for further exploration.Useful for scholars, pastors, teachers, and students—for biblical study, exegesis, or sermon preparation.Possible areas covered include details of domestic life, technology, culture, laws, or religious practices.Each article ranges from 5 to 20 pages in length. For the complete contents of Dictionary of Daily Life in Biblical and Post-Biblical Antiquity, see ISBN 9781619708617 (4-volume set) or ISBN 9781619701458 (complete in one volume).
The Dictionary of Daily Life in Biblical & Post-Biblical Antiquity is a unique reference work that provides background cultural and technical information on the world of the Hebrew Bible and New Testament from 4000 BC to approximately AD 600. Also available as a 4-volume set (ISBN 9781619708617), this complete one-volume edition covers topics from A-Z. This dictionary casts light on the culture, technology, history, and politics of the periods of the Hebrew Bible and the New Testament. Written and edited by a world-class historian and a highly respected biblical scholar, with contributions by many others, this unique reference work explains details of domestic life, technology, culture, laws, and religious practices, with extensive bibliographic material for further exploration. There are 115 articles ranging from 5-20 pages long. Scholars, pastors, and students (and their teachers) will find this to be a useful resource for biblical study, exegesis, and sermon preparation. "This is not your standard Bible dictionary, but one that focuses on aspects of daily life in Bible times, addressing interesting and sometimes puzzling topics that are often overlooked in other encyclopedias. I highly recommend the Dictionary of Daily Life in Biblical and Post-Biblical Antiquity and will be giving it 'shout-outs' in my classes in the years to come." --James K. Hoffmeier, Professor of Old Testament and Near Eastern Archaeology, Trinity Evangelical Divinity School "This wonderful resource is much more than a dictionary. It is a compendium of substantive essays on numerous facets of daily life in the ancient world. I am frequently asked by pastors and students for recommendations on books that illuminate the manners, customs, and cultural practices of the biblical world. Now I have the ideal set of books to recommend." --Clinton E. Arnold, Dean and Professor of New Testament, Talbot School of Theology, Biola University
This text is an unbound, binder-ready edition. Visualizing Psychology, Third Edition helps students examine their own personal studying and learning styles with several new pedagogical aids--encouraging students to apply what they are learning to their everyday lives while offering ongoing study tips and psychological techniques for mastering the material. Most importantly, students are provided with numerous opportunities to immediately access their understanding.
fudustrial uses of polysaccharides centre on their ability to thicken or structure many times their own weight of water, or in other words to control the rheology of hydrated systems. Until comparatively recently, however, objective characterisation of polysaccharide rheology, except in a few specialist research laboratories, was largely confined to compression of gels, simple measurements of solution viscosity, often in ill-defined geometries, and imitative tests intended to reflectproductperformance in specific areas ofend-use. Several factors have combined to bring a wider range of rheological techniques into common use. One is the increasing practical importance of systems that cannot adequately be described as solids or liquids, such as 'weak gels' and spreadable pastes. fu parallel, routine characterisation of such systems has become economically feasible with the development of a new generation of comparatively inexpensive computer-controlled instruments. There has also been a change ofemphasis from phenomenologicaldescription ofproduct texture towards the use of rheological measurements to probe the underlying molecular and supramolecular structures and the processes by which they are formed. As a result, even the most pragmatic producers and users of industrial polysaccharides are probably now familiar with terms such as creep compliance, stress overshoot and the ubiquitous G' and G", although perhaps not fully understanding their precise meaning or practical significance. A definitive text giving a rigorous description of the rheological approaches relevant to polysaccharide systems is therefore appropriate and timely. Romano Lapasin and Sabrina Priel are to be congratulated for tackling the daunting but worthwhile taskofproducing such avolume.
Making use of the only records available - pastoral visits and synodal statutes - the authors introduce fresh evidence and interpretations. They shed new light on the medieval origins of the Catholic Reformation and the nature of the reform movement in the sixteenth century. Their work shows the importance of French bishops in starting the early-modern reform and their subsequent role in preparing the Catholic Church to weather the French Revolution. They also explore both the role of the French monarchy in the creation and collapse of the Catholic Reformation, and the changing attitude of peasants and the proto-proletariat toward official religion.
The History of the Synapse provides a history of those discoveries concerning the identification and function of synapses that provide the foundations for research during this new century with a personal view of the process by which new concepts have developed. Previously published as essays, the chapters in this book provide a history of various aspects of synaptic function, beginning with the evolution over two and a half thousand years and how progress was made in the establishment of a conceptual structure that would allow the synapse to be identified at the beginning of the 20th century. Numerous illustrations explain either the technical approach or the experimental finding.
This issue of Medical Clinics of North America provides the latest essential updates on COPD. The following topics are covered: pathobiological mechanisms; genes and the disease (alpha-l-antitrypsin); the environment, phenotype, and comorbidity; the role and potential of imaging; pulmonary function and its importance; exercise in testing and therapy; patients’ perception and quality of life; exacerbations, causes, prevention, and treatment; an integrated approach to the medical treatment; meducal pneumoplasty, surgical resection, or lung transplant; and smoking cessation and environmental hygiene.
Space Transport Liability examines the national and international space transport liability principles which govern personal injury, property damage, and cargo losses caused by spacecraft. The value of maritime, aviation, and general transport analogies and law is considered. The book then considers the proper parties, forums, law, and precedents available to resolve space transport disputes. This book is as much about what space transport law will be as what it is. It will interest legislators as well as lawyers. It will assist space transport participants to structure their agreements and resolve their disputes. The cases described will assist insurers in underwriting space risks and venture capitalists in hedging their bets. For students of law, it will extend conventional principles to unconventional situations.
This work presents the state of knowledge on the endangered and threatened species of Thailand. Its pragmatic purpose is to improve Thailand’s future by providing access to technical guidance for planning development projects or other land-use changes. This information also should stimulate naturalists, professional biologists, or anyone who wishes to learn about the status of animals in Thailand. Which species are now on the brink of extinction from Thailand, and why? How can the Thai people reorganize themselves to reverse the course of destruction? Can ways be found for both the people and the rest of the fauna to prosper? Another purpose is to present a case study of the effects of longterm development for human use on the biological diversity of a tropical country.
Growth Regulation and Carcinogenesis discusses topics such as growth factors, including stimulators and inhibitors of proliferation; networks in proliferation regulation; differentiation-inducing factors; origins of neoplasia and their relationship to growth control; genetic alterations in cellular regulatory machinery; extrachromosomal phenomena; non-genotoxic carcinogens; immortalization and transformation of cells; and the role of cell production, cell function, and cell elimination in physiological growth control.
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. - Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats - Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace - Each chapter will include a map of the world showing where that particular disease is naturally found
With an emphasis on global advantage, the text offers a comprehensive examination of regional and international issues to provide a complete, accurate and up-to-date explanation of the strategic management process. New coverage on environmental concerns and emerging technologies as well as examples and cases from Australia, New Zealand and Asia-Pacific serve to engage students while updated international content demonstrates how strategic management is used in the global economy. The text takes a 'resource-based' approach, which requires the examining of a firm's unique bundling of its internal resources. This text is appropriate for upper-level undergrad, usually third year; post grad in Masters courses.
Evidence-Based Physical Diagnosis helps you choose the diagnostic approaches that have been proven most effective! Dr. Steven McGee puts the most current evidence at your fingertips, equipping you to easily select the best test for diagnosing a given condition and understand the diagnostic significance and accuracy of your findings. A remarkably easy-to-reference organization makes it simple to find the answers you need; and full-text online access at www.expertconsult.com lets you quickly reference the book from any computer or mobile device. Quickly review the history, pathogenesis, examination technique, and interpretation of physical findings for all areas of the body thanks to a very reader-friendly outline format, including more than 90 "EBM boxes" and accompanying "EBM ruler" illustrations. Get expert advice from Dr. Steven McGee, an internationally respected authority in physical examination and assessment, pain management, and education in general internal medicine. See exactly which studies document the significance of various findings thanks to thousands of up-to-date references. Access the complete contents online at www.expertconsult.com, plus a downloadable image collection and an evidence-based calculator that helps you determine probability ratios based on the evidence criteria. Apply the latest knowledge on hot topics such as the value of physical examination in taking care of the ICU patient, accurately diagnosing the etiology of systolic murmurs, diagnosing osteoarthritis and acute vertigo in the dizzy patient, diagnosing hemorrhagic stroke, and diagnosing pleural effusions. Implement the most current evidence-based approaches for evaluating stance and gait, Schamroth's sign (for clubbing), dementia, prediction of falls, hepatopulmonary syndrome, atrial fibrillation, relative bradycardia, tourniquet test (for dengue infections), acute stroke, and pleural effusion. Assess the pretest probability of disease, given particular signs or symptoms, with new at-a-glance tables. Make effective decisions thanks to updated content throughout, including new EBM boxes covering over 250 recent studies on physical diagnosis-ensuring that all diagnostic information (i.e., sensitivity, specificity, and likelihood ratios) is up to date. Increase diagnostic confidence with McGee!
First International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2005, Las Palmas, Canary Islands, Spain, June 15-18, 2005, Proceedings
First International Work-Conference on the Interplay Between Natural and Artificial Computation, IWINAC 2005, Las Palmas, Canary Islands, Spain, June 15-18, 2005, Proceedings
The two-volume set LNCS 3561 and LNCS 3562 constitute the refereed proceedings of the First International Work-Conference on the Interplay between Natural and Artificial Computation, IWINAC 2005, held in Las Palmas, Canary Islands, Spain in June 2005. The 118 revised papers presented are thematically divided into two volumes; the first includes all the contributions mainly related with the methodological, conceptual, formal, and experimental developments in the fields of Neurophysiology and cognitive science. The second volume collects the papers related with bioinspired programming strategies and all the contributions related with the computational solutions to engineering problems in different application domains.
Clinical Procedures in Emergency Medicine, by James R. Roberts, MD & Jerris R. Hedges, MD, MS, is far and away the most well-known and trusted procedures manual in emergency medicine. Completely updated with the latest equipment, devices, drug therapies, and techniques, this 5th edition enables you to make optimal use of today's best options. And a new full-color format makes the book easier to consult than ever before. You'll see exactly how and when to perform every type of emergency procedure, so you can choose and implement the best possible approach for every patient! Provides over 1,700 detailed illustrations, 1,350 in full color, allowing you to visualize procedures clearly so you can perform them correctly. Explains not only how to perform each rocedure but also why, when, and what other procedures you should consider. Covers the latest equipment, devices, drug therapies, and techniques, including new devices for cricothyrotomy, monitoring CPR effectiveness, intraosseous infusion, autotransfusion and transfusion therapy, and wound closure. Incorporates coverage of ultrasound-guided procedures throughout the book to assist you in the use of these increasingly pervasive new techniques. Presents a new chapter on Chemical and Physical Restraints to facilitate management of violent or aggressive patients. Features a brand new full-color design together with all-new algorithms, illustrations, and tables for expedited reference and streamlined clinical decision making. Reflects the most recent clinical evidence and guidelines for dependable decision-making guidance. Offers updated coverage of tracheal intubation and infectious exposure management, so you can make spilt-second decisions on these difficult procedures.
This book provides practicing pathologists, dermatologists, cutaneous oncologists and dermatopathologists with a reference textbook that reviews the clinical and histopathologic features of skin disorders that affect children, along with a discussion of the molecular pathogenesis for each disease as it is currently known. The book includes a concise discussion of the clinical presentation, as well as the histologic and, when appropriate, immunohistochemical features of each disease. The book is divided into two main sections, non-neoplastic and neoplastic skin diseases. Each section is comprised of a series of chapters organized according to histologic findings rather than by clinical classification systems. This will enable the practicing pathologist to browse chapters based upon observation of routine histologic patterns. Each chapter addresses the differential diagnoses of skin disorders with focus on salient histologic characteristics. The text is richly illustrated with over 1000 colorful clinical and histologic photographs for each of the 400 entities discussed. Pediatric Dermatopathology provides a microscope table reference for the practicing pediatric pathologist, general pathologist and dermatopathologist. Further, it will serve as a reference volume for dermatologists, pediatricians and oncologic surgeons.
Iron is of fundamental importance for the growth, development and well being of almost all living organisms. Multiple biological systems have been developed for the uptake, utilisation, storage and homeostasis of iron in microbes, plants and mammals. e.g. Both iron deficiency and iron overload are found extensively in man: the intimate links between iron and oxidative stress are associated with a wide range of pathologies; iron has a well established role in infections by a wide range of microorganisms and parasites; there is a close link between iron requirements and cellular division with implications for cancers and other metals such as copper and zinc are closely linked with iron metabolism. The first edition of this book was published in 1991. Since then the extensive impact of molecular cell biology on the field of iron biochemistry has opened new horizons in our understanding of the transport and storage of iron and of its homeostasis. The explosive use of molecular biological techniques applied to cellular biology of iron metabolism has resulted in a rapid expansion in the literature which has led to the need for this second edition. This second edition also: Introduces many illustrations and colour photos to make the basic concepts far clearer Includes new chapters on iron and cell division and interactions of iron with other metals - particularly copper and zinc Provides additional anecdotes Incorporates an extensive and up-to-date bibliography
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