This book focuses on the dynamics of clouds and of precipitating mesoscale meteorological systems. Clouds and precipitating mesoscale systems represent some of the most important and scientifically exciting weather systems in the world. These are the systems that produce torrential rains, severe winds including downburst and tornadoes, hail, thunder and lightning, and major snow storms. Forecasting such storms represents a major challenge since they are too small to be adequately resolved by conventional observing networks and numerical prediction models. Key Features* Key Highlights of This Text* Provides a complete treatment of clouds integrating the analysis of air motions with cloud structure, microphysics, and precipitation mechanics* Describes and explains the basic types of clouds and cloud systems that occur in the atmosphere-fog, stratus, stratocumulus, altocumulus, altostratus, cirrus, thunderstorms, tornadoes, waterspouts, orographically induced clouds, mesoscale convection complexes, hurricanes, fronts, and extratropical cyclones* Presents a photographic guide, presented in the first chapter, linking the examination of each type of cloud with an image to enhance visual retention and understanding* Summarizes the fundamentals, both observational and theoretical, of atmospheric dynamics, thermodynamics, cloud microphysics, and radar meteorology, allowing each type of cloud to be examined in depth* Integrates the latest field observations, numerical model simulations, and theory* Supplies a theoretical treatment suitable for the advanced undergraduate or graduate level
While steroids from the periphery have profound effects on the nervous system, the nervous system also produces its own steroids de novo (“neurosteroids”). The physiological importance of neurosteroids is beginning to be understood. These steroids potentially have roles in sedative/hypnotic behavior, anxiety, learning, and memory. At the cellular level, neurosteroids affect neuronal excitability, synaptic plasticity and cell proliferation and survival. Early findings hold promise for future strategies to treat specific psychologicalconditions and neurological diseases. This Brief will focus on the current state of understanding of brainderived neurosteroids.
This textbook provides a basic understanding of the principles of the field of organic electronics, through to their applications in organic devices. Useful for both students and practitioners, it is a teaching text as well as an invaluable resource that serves as a jumping-off point for those interested in learning, working and innovating in this rapidly growing field. Organics serve as a platform for very low cost and high performance optoelectronic and electronic devices that cover large areas, are lightweight, and can be both flexible and conformable to fit onto irregularly shaped surfaces such as foldable smart phones. Organic electronics is at the core of the global organic light emitting device (OLED) display industry. OLEDs also have potential uses as lighting sources. Other emerging organic electronic applications include organic solar cells, and organic thin film transistors useful in medical and a range of other sensing, memory and logic applications. This book is a product of both one and two semester courses that have been taught over a period of more than two decades. It is divided into two sections. Part I, Foundations, lays down the fundamental principles of the field of organic electronics. It is assumed that the reader has an elementary knowledge of quantum mechanics, and electricity and magnetism. A background knowledge of organic chemistry is not required. Part II, Applications, focuses on organic electronic devices. It begins with a discussion of organic thin film deposition and patterning, followed by chapters on organic light emitters, detectors, and thin film transistors. The last chapter describes several devices and phenomena that are not covered in the previous chapters, since they lie somewhat outside of the current mainstream of the field, but are nevertheless important.
Progress in Heterocyclic Chemistry: Volume 34, the latest in this annual review series commissioned by the International Society of Heterocyclic Chemistry (ISHC), contains both highlights of the previous year’s literature on heterocyclic chemistry and articles on new developing topics of particular interest to heterocyclic chemists. Highlight chapters in Volume 34 are all written by leading researchers in their field, thus constituting a systematic survey of the important original material reported in the literature of heterocyclic chemistry in 2021. As with previous volumes in the series, Volume 34 will enable academic and industrial chemists and advanced students to keep abreast of developments in heterocyclic chemistry in a convenient way. Recognized as the premiere review of heterocyclic chemistry Includes contributions from leading researchers in the field Provides a systematic survey of the important 2021 heterocyclic chemistry literature Presents articles on new and developing topics of interest to heterocyclic chemist
The definitive bible for the field of biomedical engineering, this collection of volumes is a major reference for all practicing biomedical engineers and students. Now in its fourth edition, this work presents a substantial revision, with all sections updated to offer the latest research findings. New sections address drugs and devices, personalized medicine, and stem cell engineering. Also included is a historical overview as well as a special section on medical ethics. This set provides complete coverage of biomedical engineering fundamentals, medical devices and systems, computer applications in medicine, and molecular engineering.
With the development of courses on materials synthesis and the need to carry out specific chemical transformations in the laboratory, good practical advice will be needed for those requiring more detail on conjugated materials synthesis. The purpose of this book is to give researchers and students an introduction and reference that efficiently provides general information for each important synthetic method category and a number of examples from the literature to convey practically important variations. It is useful as an outline for advanced organic and materials science courses as well as a good introduction and desk reference for new and experienced researchers in the field.
Autophagy and Cardiometabolic Diseases: From Moleculer Mechanisms to Translational Medicine covers the science of autophagy in relation to cardiometabolic diseases and the future therapeutic potentials of autophagy regulation in these processes. Processes are not described in isolation, but in concert with other cellular and/or metabolic processes, such as lipogenesis, glucose, energy metabolism and apoptosis. This approach recognizes the multifactorial nature of cardiometabolic diseases, including obesity, diabetes, insulin resistance, hypertension and dyslipidemia. The book provides explanations, while also distinguishing the delicate role for autophagy in pathogenesis and exploring complications for cardiometabolic diseases. By targeting autophagy, it offers new avenues for drug discovery and treatment for cardiometabolic anomalies. It is a perfect resource for cardiology researchers, scientists and medical practitioners. Explains the processes inherent in the protein quality control for pathogenesis and complications of cardiometabolic diseases Provides knowledge from internationally recognized contributors in the field Incorporates a translational approach, covering the basic cellular biology of autophagy and presenting the role of autophagy regulation for both pathogenesis and complication in cardiometabolic diseases Contains access to a companion website with additional illustrations
Patterned after the renowned Walls Manual of Emergency Airway Management, Manual of Airway Management in Critical Care is a concise, focused reference on this challenging topic specifically for ICU providers. Drs. Jarrod M. Mosier, Calvin A. Brown III, Matteo Parotto, and Raquel R. Bartz bring their extensive expertise in critical care airway management to this all-new volume, as well as Dr. Mosier’s experience as director of the nationally recognized The Difficult Airway Course: Critical CareTM. An excellent resource for intensivists, advanced practice providers, critical care nurses, and respiratory therapists, this first-of-its-kind text reflects ICU airway management from cover to cover: its unique standards of care, its unique risks, and its unique body of literature that set it apart from other medical disciplines.
Ideal for entry-level and experienced researchers working in materials science and engineering, this unique book introduces a new subfield of materials science and mechanics of materials: network materials. A comprehensive review of their mechanical behaviours allows readers to understand, design, and enhance the performance of these material systems, across a range of materials including cytoskeletons, connective tissue, and thermoset polymers. By introducing simple models, supported by experimental data, the book provides the necessary fundamental knowledge to assist readers to design and develop their own material systems. By presenting each of these previously disparate material systems within a unified theoretical framework, this book provides a consolidated presentation of the mechanics of networks and their interactions, introducing parameters that define the stochastic structure of the network, and discussing their mechanical behaviour. It is an ideal text for those new to this fast-growing field, and for experienced researchers looking to consolidate their knowledge.
A timely, accessible survey of the multidisciplinary field of bioanalytical chemistry Provides an all in one approach for both beginners and experts, from a broad range of backgrounds, covering introductions, theory, advanced concepts and diverse applications for each method Each chapter progresses from basic concepts to applications involving real samples Includes three new chapters on Biomimetic Materials, Lab-on-Chip, and Analytical Methods Contains end-of-chapter problems and an appendix with selected answers
Hepatocyte and Kupffer Cell Interactions presents a comprehensive discussion of historical and recent information regarding this diverse field of research. The role of Kupffer cells and hepatoctyes in normal physiology, nonseptic pathological states, and in sepsis is examined. Microanatomy and methods of experimental study are covered as well. In each of the book's chapters, the role of the Kupffer cell and hepatocyte interaction is placed in context with information on particular liver functions or disease states. Hepatocyte and Kupffer Cell Interactions is an essential reference for leukocyte specialists, gastroenterologists, immunologists, and other researchers working in this fascinating field.
In recent years there has been an explosion of interest in the production of nanoscale fibres for drug delivery and tissue engineering. Nanofibres in Drug Delivery aims to outline to new researchers in the field the utility of nanofibres in drug delivery, and to explain to them how to prepare fibres in the laboratory. The book begins with a brief discussion of the main concepts in pharmaceutical science. The authors then introduce the key techniques that can be used for fibre production and explain briefly the theory behind them. They discuss the experimental implementation of fibre production, starting with the simplest possible set-up and then moving on to consider more complex arrangements. As they do so, they offer advice from their own experience of fibre production, and use examples from current literature to show how each particular type of fibre can be applied to drug delivery. They also consider how fibre production could be moved beyond the research laboratory into industry, discussing regulatory and scale-up aspects.
The ability to culture cells is fundamental for mass propagation and as a baseline for the genetic manipulation of plant nuclei and organelles. The introduction to Plant Cell Culture: Essential Methods provides a general background to plant cell culture, including basic principles, technologies and laboratory practices that underpin the more detailed techniques described in subsequent chapters. Whilst each chapter provides a background to the topic area and methodology, a crucial aspect is the provision of detailed protocols with emphasis on trouble shooting, describing common problems and detailed advice for their avoidance. Plant Cell Culture: Essential Methods provides the reader with a concise overview of these techniques, including micropropagation, mutagenesis, cryopreservation, genetic and plastid transformation and somatic cell technologies. This book will be an essential addition to any plant science laboratory's bookshelf. Highlights the best and most up-to-date techniques for working on plant cell culture Explains clearly and precisely how to carry out selected techniques in addition to background information on the various approaches Chapters are written by leading international authorities in the field and cover both well-known and new, tried and tested, methods for working in plant cell culture An essential laboratory manual for students and early-career researchers.
This shortform textbook provides a comprehensive overview of international economics and coverage of recent trends in the global economy to supplement students’ knowledge of this fast-moving subject area. Divided into two parts, the book begins by introducing the fundamental aspects of international economics (the international economic system, global networks and flows, the theory of international trade, trade policy, trade agreements, foreign exchange market, international factor movements, and developing countries) before moving on to focus on specialist topics such as the Covid-19 pandemic, the emerging economies of BRICS, and Brexit. Each chapter includes an essential summary, key terms, study questions, and references. The book is accompanied by a suite of digital resources, including a test bank of questions, PowerPoints slides, answers to chapter questions, and an instructor’s manual. As part of the Absolute Essentials of Business and Economics series, the book provides a straightforward way for students to learn about international economics, and will be invaluable reading for any student studying the global economy as part of a business, economics or international studies degree programme.
This book presents the synthetic methodologies as well as the properties and potential usage of various ruthenium-containing materials. Starting from the first examples of 'ruthenopolymers' reported in the 1970s to the 3D architectures now synthesized, these materials have shown their importance far beyond fundamental polymer science. As well as highlighting the remarkable properties and versatile applications, this book also addresses a key question related to the applications of such heavy-metal-containing materials from the perspective of achieving a sustainable future. This book is of interest to both materials scientists and chemists in academia and industry.
VOLUME 1: INFERTILITY SECTION 1: ANATOMY AND PHYSIOLOGY 1. Anatomy of the Reproductive System 2. Regulation and Physiology of Menstrual Cycle 3. Oogenesis and Folliculogenesis 4. Spermatogenesis 5. Fertilization and Embryogenesis 6. Implantation 7. Embryo Endometrial Crosstalk and Endometrial Receptivity SECTION 2: REPRODUCTIVE ENDOCRINOLOGY 8. Synthesis and Metabolism of Steroid Hormones 9. Puberty and Aberrations 10. Amenorrhea 11. Endocrine Disorders Affecting Reproduction 12. Hirsutism 13. Luteal Phase Defect 14. Anovulation 15. Declining Fertility SECTION 3: COMBINED TOPICS 16. Evaluation of Infertility 17. Immunology and Infertility 18. Cytogenetics and Subfertility 19. Obesity and Infertility 20. Unexplained Infertility 21. Fertility Preservation 22. Counseling in Infertility 23. Assisted Reproductive Technology in Patients with Chronic Medical Disorders SECTION 4: MALE INFERTILITY 24. Etiopathogenesis of Male Infertility 25. Clinical and Endocrinological Evaluation of Infertile Male 26. Sexual Dysfunction in Male Infertility 27. Ultrasound in Male Infertility 28. Medical Management of Male Infertility 29. Azoospermia: Evaluation and Management 30. Varicocele and Infertility 31. Spinal Cord Injuries and Male Infertility 32. Algorithms for Genetic Evaluation of Infertile Males SECTION 5: FEMALE FACTOR INFERTILITY 33. Uterine Factors in Infertility 34. Tubal Factors in Infertility 35. Infections and Infertility 36. Tuberculosis and Infertility 37. Sonoendocrinology and Cycle Monitoring Assisted Reproduction Technology 38. Transvaginal Ultrasound and Doppler in Infertility 39. Polycystic Ovary Syndrome 40. Assessment of Ovarian Reserve 41. Endometriosis 42. Endoscopy in Infertility 43. Reconstructive Surgeries Enhancing Fertility SECTION 6: INTRAUTERINE INSEMINATION 44. Intrauterine Insemination 45. Optimizing Success in Intrauterine Insemination SECTION 7: OVARIAN STIMULATION 46. Drugs for Ovarian Stimulation 47. Ovulation Induction and Ovarian Stimulation Protocols 48. Role of Adjuvants in Ovarian Stimulation 49. Gonadotropinreleasing Hormone Analogs 50. Monitoring of Ovarian Stimulation 51. Ovulation Trigger 52. Individualized Controlled Ovarian Stimulation 53. In Vitro Fertilization Lite 54. Role of Luteinizing Hormone in Ovarian Stimulation 55. Anesthesia in Assisted Reproductive Techniques 56. Oocyte Retrieval. 57. Embryo Transfer 58. Troubleshooting in Assisted Reproductive Technology 59. Luteal Phase Support SECTION 8: DILEMMA IN ART 60. Poor Responder 61. Recurrent Implantation Failure 62. Empty Follicle Syndrome 63. Role of Aneuploidy Screening in Preimplantation Embryos 64. Preimplantation Genetic Testing of Embryos 65. Epigenetics and Assisted Reproductive Technology SECTION 9: COMPLICATIONS IN ART 66. Ovarian Hyperstimulation Syndrome 67. Ectopic Pregnancy 68. Multipleorder Births SECTION 10: THIRD PARTY REPRODUCTION 69. Oocyte and Sperm Donation 70. Surrogacy in Assisted Reproductive Technology 71. Assisted Reproductive Technology Guidelines 72. Adoption 73. LGBTQ and Fertility 74. Transgender Population and Fertility SECTION 11: OUTCOME FOLLOWING ASSISTED REPRODUCTIVE TECHNIQUE 75. Maternal and Fetal Outcomes Following Assisted Reproductive Technique 76. Early Pregnancy Scan 77. Recurrent Pregnancy Loss: From Diagnostic Dilemmas to Clinical Decisions SECTION 12: RECENT ADVANCES 78. Bioengineered Human Endometrium In Vitro. 79. Recent Trends in A...
Comprehensive in scope and thoroughly up to date, Wintrobe’s Clinical Hematology, 15th Edition, combines the biology and pathophysiology of hematology as well as the diagnosis and treatment of commonly encountered hematological disorders. Editor-in-chief Dr. Robert T. Means, Jr., along with a team of expert section editors and contributing authors, provide authoritative, in-depth information on the biology and pathophysiology of lymphomas, leukemias, platelet destruction, and other hematological disorders as well as the procedures for diagnosing and treating them. Packed with more than 1,500 tables and figures throughout, this trusted text is an indispensable reference for hematologists, oncologists, residents, nurse practitioners, and pathologists.
Interfacial Science for Geosystems Engineers provides geoscientists the connections between the nano-scale physico-chemical interactions between fluids and minerals and the core/field-scale observations to manage energy extraction, water resources and subsurface storage, timely topics central to the energy transition. Packed with latest research and recent developments, chapter learning objectives, and illustrative diagrams, tables and charts throughout, this specialized volume will help geosystems engineers tackle the above challenges, by systematically going through the basics of surface and interfacial tension, capillarity, surfactants, surface free energy, adsorption, electrokinetics, colloidal stability, equilibrium and stability of thin liquid films, wettability, microemulsions, emulsions and foams, and polymers for subsurface applications. Useful as a teaching, training or reference text, Interfacial Science for Geosystems Engineers prepares today’s subsurface scientists and engineers to tackle two pressing problems in the energy transition, by introducing recent developments on how to remove CO2 from our environment and how to wean ourselves off fossil energy while meeting growing energy demands. Describes fundamentals and recent advances in interface and nanoparticle/colloid dispersion science Offers critical analysis of the latest research and developments relevant to extracting low-carbon and other energy materials from, and store CO2 and H2 in, subsurface formations Helps guide geosystems (especially energy) engineers on how to solve the problems they encounter in the rapidly evolving Energy Transition
Written by the world’s foremost leaders in the field of nosocomial infections, Bennett & Brachman’s Hospital Infections, 7th Edition, is a must-have text for preventing Hospital-Acquired Infections (HAIs) in all inpatient and outpatient healthcare settings. This comprehensive volume provides up-to-date, authoritative coverage on all aspects of this vital topic, with editor Dr. William R. Jarvis leading a team of notable contributors from the U.S. Centers for Disease Control and Prevention, as well as additional authors who provide an international perspective on HAIs. The newly revised and expanded seventh edition continues to be an invaluable resource for anyone working in infection prevention and control, quality assurance or risk management in healthcare settings.
This book provides an overview on the latest advances in the synthesis, properties and applications of polymeric eco-composites and eco-nanocomposites reinforced natural fibers (e.g. pulp-fiber, flax, etc.) and nanofillers (e.g. organoclay, nano-SiC, etc.). Potential challenges and future directions of these composites are highlighted and addressed. This book offers numerous graphs and electron micrographs for easy understanding by students, researchers and practicing engineers.
This Ph.D. thesis attempts to decipher the closure of the Palaeozoic Palaeo-Asian Ocean along the enigmatic Solonker Suture in East Asia adopting a methodology that integrates geochemical and geochronological data from Palaeozoic sedimentary and volcanic rocks in the region. It provides an in-detail but also broad insight into the Palaeozoic to early Mesozoic tectonic evolution of the region, not only pin-pointing the debated location of the Solonker Suture but also the timing of final disappearance of the Palaeo-Asian Ocean during Permian to Early Triassic times. The results have led to propose a tectonic ‘soft-collision’ model for the amalgamation of the North China Craton and the Mongolian Terranes in northern Asia explaining the general absence of geologic features characteristic for continent-continent collisions such as the occurrence of regional-scale high-grade metamorphic rocks, ophiolite belts and fold-thrust structures. This new model may serve as a blueprint for the tectonic evolution of similar suture zones that are characterized by the absence of typical collision related lithologies and structures. The thesis is particularly useful as a guide for researchers who seek an in-depth understanding of the Palaeozoic to early Mesozoic tectonic evolution of northern China and Central Asia along the Solonker Suture.
The full-color Avoiding Common Anesthesia Errors, significantly updated for this second edition, combines patient safety information and evidence-based guidance for over 300 commonly encountered clinical situations. With a format that suggests conversations between an attending and a trainee, the book helps you identify potential problems and develop a treatment plan to minimize the problem. Brief, easy-to-read chapters cover basic and advanced topics and help you digest information in minutes!
The last 20 years has seen a rapid increase in infectious diseases, particularly those that are termed "emerging diseases" such as SARS, "neglected diseases" such as malaria and those that are deemed biothreats such as anthrax. It is well-recognized that the most effective modality for preventing infectious diseases is vaccination. This book provides researchers with a better understanding of what is currently known about these diseases, including whether there is a vaccine available or under development. It also informs readers of the key issues in development of a vaccine for each disease. Provides a comprehensive treatise of the agents that are responsible for emerging and neglected diseases and those that can be used as biothreats Includes the processes such as the vaccine development pathway, vaccine manufacturing and regulatory issues that are critical to the generation of these vaccines to the marketplace Each chapter will include a map of the world showing where that particular disease is naturally found
The third edition of this established classic text reference builds upon the strengths of its very popular predecessors. Organized as a broadly useful textbook Principles of Fluorescence Spectroscopy, 3rd edition maintains its emphasis on basics, while updating the examples to include recent results from the scientific literature. The third edition includes new chapters on single molecule detection, fluorescence correlation spectroscopy, novel probes and radiative decay engineering. Includes a link to Springer Extras to download files reproducing all book artwork, for easy use in lecture slides. This is an essential volume for students, researchers, and industry professionals in biophysics, biochemistry, biotechnology, bioengineering, biology and medicine.
Recognized as the definitive reference in laboratory medicine since 1908, Henry's Clinical Diagnosis continues to offer state-of-the-art guidance on the scientific foundation and clinical application of today's complete range of laboratory tests. Employing a multidisciplinary approach, it presents the newest information available in the field, including new developments in technologies and the automation platforms on which measurements are performed. Provides guidance on error detection, correction, and prevention, as well as cost-effective test selection. Features a full-color layout, illustrations and visual aids, and an organization based on organ system. Features the latest knowledge on cutting-edge technologies of molecular diagnostics and proteomics. Includes a wealth of information on the exciting subject of omics; these extraordinarily complex measurements reflect important changes in the body and have the potential to predict the onset of diseases such as diabetes mellitus. Coverage of today's hottest topics includes advances in transfusion medicine and organ transplantation; molecular diagnostics in microbiology and infectious diseases; point-of-care testing; pharmacogenomics; and the microbiome. Toxicology and Therapeutic Drug Monitoring chapter discusses the necessity of testing for therapeutic drugs that are more frequently being abused by users.
For nearly 40 years, Rosen’s Emergency Medicine has provided emergency physicians, residents, physician assistants, and other emergency medicine practitioners with authoritative, accessible, and comprehensive information in this rapidly evolving field. The fully revised 10th Edition delivers practical, evidence-based knowledge and specific recommendations from clinical experts in a clear, precise format, with focused writing, current references, and extensive use of illustrations to provide definitive guidance for emergency conditions. With coverage ranging from airway management and critical care through diagnosis and treatment of virtually every emergency condition, from highly complex to simple and common, this award-winning, two-volume reference remains your #1 choice for reliable, up-to-date information across the entire spectrum of emergency medicine practice. Please note the following important change for printed copies of Rosen’s Emergency Medicine, 10e. On page 1029, in table 74.3, the dosage for Rivaroxaban should be 15mg by mouth. You may contact Elsevier Customer Service to request a sticker (Part no. 9996133834) to make the correction in your printed copy. Corrections have been made to the eBook versions of this title. Offers the most immediately clinically relevant content of any emergency medicine resource, providing diagnostic and treatment recommendations and workflows with clear indications and preferred actions. Contains eight entirely new chapters covering coronaviruses/COVID-19, the morbidly obese patient, human trafficking, sexual minority (LGBTQ) patients, social determinants of health, community violence, and humanitarian aid in war and crisis. Features over 1,700 figures, including more than 350 new anatomy drawings, graphs and charts, algorithms, and photos. Includes new information across the spectrum of emergency care, such as adult and pediatric airway management, shock, pandemic disease, emergency toxicology, sepsis syndrome, resuscitation, medical emergencies of pregnancy, the immunocompromised patient, child abuse, pediatric sedation, pediatric trauma, and more. Features revised and refined chapter templates that enhance navigation, making it easy to find key information quickly. Provides access to more than 1,200 questions and answers online to aid in exam preparation, as well as two dozen new video clips showing how to best perform critical emergency procedures in real time. Reviewed and verified cover-to-cover by a team of expert clinical pharmacists to ensure accuracy and completeness of all drug information and treatment recommendations.
The standard-setting reference in medical toxicology—trusted as the leading evidencebased resource for poison emergencies A Doody's Core Title for 2017! For decades, one name has been synonymous with the most respected, rigorous perspectives on medical toxicology and the treatment of poisoned and overdosed patients: Goldfrank's Toxicologic Emergencies. Presented in full color, Goldfrank’s delivers essential, patientcenteredcoverage of every aspect of poison management. The editors and authors are recognized as preeminent scholars in their specialties and provide unmatched coverage of all aspects of toxicologic emergencies, from pharmacology and clinical presentation to cutting-edge treatment strategies. Goldfrank's Toxicologic Emergencies, Tenth Edition begins with an examination of medical toxicology principles and techniques. It then reviews the biochemical, molecular, and pathophysiologic basis of toxicology, followed by an intense focus on toxicologic principles related to special patient populations. Features Case studies enhance your understanding of the clinical application of the text material Practical focus on the pathophysiologic basis of medical toxicology The Antidotes in Depth sections delivers the expertise of toxicologists across the world as they present treatments for critically ill poisoned and overdosed patients and allow you to easily identify key issues relating to the use of complex and often unfamiliar therapies The principles of risk management, medicolegal decision making, patient safety, post mortem toxicology and the assessment of ethanol induced impairment described in chapters and Special Considerations emphasize the interface between medical toxicology, the law, and quality care
The most trusted, rigorous, and up-to-date toxicology resource and educational companion available – now in full color Goldfrank’s Toxicologic Emergencies continues to be the source you can turn to first for any poisoning or overdose. The text provides clear information on every aspect of toxicologic emergencies, from pharmacology to clinical presentation to management. Fully referenced and featuring a consistent organization, Goldfrank’s begins with an in-depth examination of general principles of medical toxicology. It then progresses to the biochemical principles and molecular basis of toxicology, and provides detailed insight into how xenobiotics affect vital signs, organs, and systems throughout the body. Next, a wide spectrum of clinically important exposures -- including drugs, plants, metals, household products, occupational and environmental xenobiotics are covered within logical categories for easy access to information. Finally, the book concludes with sections on principles of practicing clinical toxicology in today’s challenging healthcare environment. NEW TO THIS EDITION Full-color design and uniformly drawn figures clarify key concepts Special Considerations focus on decision-making in unique toxicologic circumstances, that influence clinical practice and have the potential to improve patient care Antidotes in Depth, following pertinent chapters, place each antidote in its proper context to ensure immediate availability of essential information relevant for clinical use More clinically-relevant figures and quick-reference tables Online learning center, available at www.goldfrankstoxicology.com, includes case studies, and a database of multiple choice questions that allow you to create a custom test for review and study. Every chapter is thoroughly rewritten and new chapters are added to reflect the very latest thinking in the field Here's why Goldfrank's is known worldwide as the field's leading text: General Approach to Medical Toxicology; The Biochemical and Molecular Basis of Medical Toxicology; The Pathophysiologic Basis of Medical; Toxicology: The Organ System Approach; The Clinical Basis of Medical Toxicology: Analgesics and Nonprescription Medications; Prescription Medications Psychopharmacologic Medications; Alcohols and Drugs of Abuse; Food Poisoning; Botanicals; Heavy Metals; Household Toxins; Pesticides; Occupational and Environmental Toxins; Toxic Envenomations; V. Special Populations; Preventive, Psychosocial, Nursing, Epidemiologic, Research & Legal Perspectives.
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