Pratima Sinha's Books

Cancer Immunotherapy

Chapter 28. Tumor-induced Myeloid-derived Suppressor Cells

By: Suzanne Ostrand-Rosenberg,Pratima Sinha,Daniel W. Beury,Olesya Chornoguz,Katherine H. Parker

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Cancer Immunotherapy

Chapter 28. Tumor-induced Myeloid-derived Suppressor Cells

By: Suzanne Ostrand-Rosenberg,Pratima Sinha,Daniel W. Beury,Olesya Chornoguz,Katherine H. Parker

Immune escape and inflammation are now recognized as hallmarks of tumor onset and progression. Myeloid-derived suppressor cells (MDSC), a heterogeneous population of immature myeloid cells that are present in virtually all patients and mice with advanced cancer, are a major contributor to immune escape through their inhibition of innate and adaptive antitumor immunity. Immature myeloid cells with the phenotype of MDSC are present in low levels in healthy individuals; however, chronic inflammation perturbs normal myelopoiesis and mobilizes MDSC, thereby facilitating tumor growth. This chapter reviews the experimental and patient findings that identified MDSC as an immune suppressive cell population mediating tumor immune escape, the phenotypic characteristics and heterogeneity of MDSC from cancer patients and mice, the diversity of mechanisms used by MDSC to facilitate tumor progression and metastasis, the pro-inflammatory mediators that drive the induction and accumulation of MDSC, and therapeutic approaches that have been developed to reduce MDSC levels and/or impair MDSC function.

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Elsevier Inc. Chapters

Published Date

ISBN 10

0128059249

ISBN 13

9780128059241

Biobased Polymers

Properties and Applications in Packaging

By: Pratima Bajpai

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Biobased Polymers

Properties and Applications in Packaging

By: Pratima Bajpai

Biobased Polymers: Properties and Applications in Packaging looks at how biopolymers may be used in packaging as a potential green solution. The book addresses bio-based feedstocks, production processes, packaging types, recent trends in packaging, the environmental impact of bio-based polymers, and legislative demands for food contact packaging materials. Chapters explore opportunities for biopolymers in key end-use sectors, the penetration of biopolymer based concepts in the packaging market, and barriers to widespread commercialization. As the development of bio-based material is an important factor for sustainably growing the packaging industry, these recent trends in consumer markets are extremely important as we move towards greener packaging. Hence, this resource is an invaluable addition on the topic. - Offers a comprehensive introduction to the subject for researchers interested in bio-based products, green and sustainable chemistry, polymer chemistry and materials science - Covers the market for bio-based materials - Includes discussions on legislative demands for food contact packaging materials - Describes interesting new technologies, including nanotechnology approaches

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Page Count

252

Publisher

Elsevier

Published Date

ISBN 10

0128184051

ISBN 13

9780128184059

Karma and Creativity

By: Christopher Key Chapple,Navin and Pratima Doshi Professor of Indic and Comparative Theology Christopher Key Chapple

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Karma and Creativity

By: Christopher Key Chapple,Navin and Pratima Doshi Professor of Indic and Comparative Theology Christopher Key Chapple

The conception of karma in the religious traditions of India has prompted numerous interpretations, many of which equate karma with notions of fate. Karma and Creativity presents a perspective on karma that emphasizes the efficacy of human activity in bringing about desired results--from upholding societal order to the attainment of spiritual liberation. Karma is examined in light of several classical Indian texts. Special attention is given to the concept of mind-only in both Hinduism and Buddhism. The study focuses on the positive approach to action first learned by the sage Vasisin the Mahabharata and then taught by him to Sri Rama in the Yogavasis. It concludes with an exploration of the theological and ethical implications of action and creativity.

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Page Count

162

Publisher

SUNY Press

Published Date

ISBN 10

0887062504

ISBN 13

9780887062506

Developments and Applications of Enzymes From Thermophilic Microorganisms

By: Pratima Bajpai

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Developments and Applications of Enzymes From Thermophilic Microorganisms

By: Pratima Bajpai

Developments and Applications of Enzymes from Thermophilic Microorganisms extensively presents the industrial application of thermophilic/hyperthermophilic enzymes. The book brings thorough and in-depth coverage on the role of these enzymes in a broad range of industries, focusing on present scenarios of these enzymes in biofuel industries, including recent advancements. The use of thermophilic enzymes in 2G biorefineries may enable the whole production process to take place at high temperatures, allowing increased reaction rate and reduced costs. Researchers in biochemistry, microbiology, microbial technology, biotechnology, molecular biology and bioresource technology will benefit from the new insights given on potential applications of hyperthermophiles. Hyperthermophilic enzymes, many of which survive at temperatures at or above 100C, contain novel macromolecules and metabolic systems which represent a vast resource for fundamental molecular and physiological studies, and for potential exploitation in biotechnology. - Covers the role of thermophilic/hyperthermophilic enzymes in a broad range of industries - Explains the Importance of thermophilic/hyperthermophilic enzymes in biorefineries using examples of lignocellulose and starch conversions to desired products - Discusses the existing and potential applications of thermophiles/hyperthermophilic enzymes

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Page Count

316

Publisher

Elsevier

Published Date

ISBN 10

0443191980

ISBN 13

9780443191985

Biotechnology of Terpenoid Production from Microbial Cell Factories

By: Pratima Gupta,Suresh Phulara

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Biotechnology of Terpenoid Production from Microbial Cell Factories

By: Pratima Gupta,Suresh Phulara

Biotechnology of Terpenoid Production from Microbial Cell Factories is a unique reference to help researchers, scientists and scholars explore available strategies involved in the production of terpenoid-based, value-added compounds from GRAS status (Generally Recognized as Safe by FDA) microbes to address the associated challenges for the industry. The book covers the most up-to-date information about microbial terpenoid production, including culture condition modulation for the improved and high-specificity production of terpenoid and their in-situ extraction. Each class of terpenoid is explained in detail, including their nutritional and pharmaceutical information and their molecular aspects. - Provides an in-depth look at both the natural and metabolic engineering aspects of microbial terpenoid production - Includes production strategies and existing challenges for each class of terpenoid from microbial sources - Presents broad application opportunities of terpenoids such as food additives, pharmaceuticals and fragrances - Includes brief chapter summaries and a glossary for each chapter to simplify technical applications

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Page Count

226

Publisher

Academic Press

Published Date

ISBN 10

0128231785

ISBN 13

9780128231784

Microbial Xylanolytic Enzymes

By: Pratima Bajpai

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Microbial Xylanolytic Enzymes

By: Pratima Bajpai

Microbial Xylanolytic Enzymes describes the enzyme structure and its interaction with plant cell walls, the properties and production of different enzymes and their applications, and the knowledge gathered on the hydrolysis mechanism of hemicellulose. The knowledge gathered about the hydrolysis mechanism of the hemicelluloses, especially xylans, has greatly promoted the rapid application of these enzymes in new areas. In recent years, there has been a spurt of interest in xylan degrading enzymes due to their applications in several industrial processes, including paper and pulp industries, food and feed industries, biofuel industry, textile industry, chemical and pharmaceutical industry, brewing industry, and more. Xylan is the principal type of hemicellulose. An enzymatic complex is responsible for the hydrolysis of xylan, but the main enzymes involved are enzymes produced by fungi, bacteria, yeast, algae, protozoans, and more. - Gives up-to-date authoritative information and cites pertinent research on the synergistic action of xylanolytic enzymes - Includes studies on xylanase regulation and synergistic action between multiple forms of xylanase - Covers, in great depth, all aspects of Xylanolytic enzymes - Includes detailed descriptions on Xylanolytic enzymes as a supplement in animal feed, for the manufacture of bread, food and drinks, textile industry, pulp and paper industry, biofuel industry and production of pharmaceuticals and important chemicals and waste management, etc. - Challenges future trends in the commercial production and application of xylanases

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Page Count

246

Publisher

Academic Press

Published Date

ISBN 10

032399637X

ISBN 13

9780323996372

Carbon Fiber

By: Pratima Bajpai

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Carbon Fiber

By: Pratima Bajpai

Carbon Fiber, Second Edition, brings together available information on the production, properties, application and future of carbon fibers. This book will be of interest to those involved in the investigation of carbon fiber, carbon fiber manufacturing, and users. In addition, the recycling of carbon fiber reinforced polymers and the manufacturing of composites from recycled carbon fiber reinforced polymers are discussed. The book offers in-depth coverage on the production of carbon fiber and the global carbon fiber market, demand and major growth drivers. Carbon structures from biowaste, waste lignin and novel processes to obtain high purity lignin are presented, along with future directions. - Provides thorough and in-depth coverage of carbon fiber production - Presents the global carbon fiber market, demand and major growth drivers - Covers carbon structures from biowaste and waste lignin - Discusses novel process to obtain high purity lignin - Includes discussions of future directions for the carbon fiber industry

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246

Publisher

Elsevier

Published Date

ISBN 10

012821905X

ISBN 13

9780128219058

Single Cell Protein Production from Lignocellulosic Biomass

By: Pratima Bajpai

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Single Cell Protein Production from Lignocellulosic Biomass

By: Pratima Bajpai

This book focuses on bioconversion of lignocellulosic residues into single-cell protein, which offers an alternative to conventional proteins (such as soybean meal, egg protein or meat protein in animal feed) that is not affected by the climate. It provides an overview of the general uses of lignocellulosic residues and their bioconversion into single-cell protein using microorganisms, as well as the recovery of the valuable by-products. It also explores the benefits and potential drawbacks of single-cell protein, with an emphasis on the economic advantages of such processes. Given its multidisciplinary scope, the book represents a valuable resource for academics and industry practitioners interested in the production of single-cell protein from lignocellulosic residues.

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Springer

Published Date

ISBN 10

9811058733

ISBN 13

9789811058738

Cellulases in the Biofuel Industry

By: Pratima Bajpai

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Cellulases in the Biofuel Industry

By: Pratima Bajpai

Cellulases in the Biofuel Industry discusses how the properties of cellulases affects the quality of the biofuels produced. Heralded as the solution to humanity's energy problem and the savior of the world's climate, extensive research is being carried out on biofuels but there are still gaps in our understanding. This book presents cost-effective and current scenarios for cellulase production in the biofuel industry, including the most recent advancements for obtaining cellulases with higher activity on pre-treated biomass substrates by screening and sequencing new organisms, engineering cellulases with improved properties, and by identifying proteins that can stimulate cellulases. The mechanism and efficiency of the cellulase enzyme system on cellulose is discussed with the specific classification of each cellulase enzyme, as well as explanations of the limitation of cellulases in terms of their production processes, efficiency and practical applications to biofuels. Various approaches to improve the production and efficiency of the cellulase enzyme system are evaluated, along with the current limitations that are hampering cost-effective production of cellulase and guidance on how these limitations might be resolved. - Includes different approaches to improve the production and efficiency of the cellulase enzyme system - Discusses the current limitations hampering the cost-effective production of cellulases - Provides case studies that include essential information for those looking to adapt cellulases technology

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Page Count

270

Publisher

Elsevier

Published Date

ISBN 10

0323994970

ISBN 13

9780323994972

Microorganisms and enzymes for lignocellulosic biorefineries

By: Pratima Bajpai

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Microorganisms and enzymes for lignocellulosic biorefineries

By: Pratima Bajpai

Enzymes and Microorganisms for Lignocellulosic Biorefinery comprehensively deals with the enzymes and microorganisms for lignocellulosic degradation, challenges in the engineering of lignocellulolytic enzymes and mining and engineering for better enzymes. The book discusses commonly used bioprocesses for lignocellulosic biorefinery, including separated hydrolysis and fermentation, simultaneous saccharification and fermentation and consolidated bioprocessing. Among these methods, construction of microbial co-culturing systems via consolidated bioprocessing is regarded as a potential strategy to efficiently produce biochemicals and biofuels, providing theoretical direction for constructing efficient and stable biorefinery process system in the future. The book discusses construction of high-performance enzyme cocktails, and presents progress witnessed in engineering lignocellulolytic enzymes and enzyme-producing microorganisms and future perspectives in the context of developing cost-effective lignocellulose conversion processes. - Presents drivers for biorefinery industry development - Discusses global drivers toward the advancement of lignocellulosic biorefineries, along with technical and operational challenges for industrialization to overcome said challenges - Discusses the biorefinery value chain and its economical and technical considerations - Provides SWOT analysis and future directions

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Page Count

256

Publisher

Elsevier

Published Date

ISBN 10

0443215022

ISBN 13

9780443215025

Recycling and Deinking of Recovered Paper

By: Pratima Bajpai

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Recycling and Deinking of Recovered Paper

By: Pratima Bajpai

Recycling and Deinking of Recovered Paper, Second Edition covers recent advances in recycling technologies. This second edition examines this new process, which is more eco-friendly than the virgin-papermaking process, and which uses less energy and natural resources, produces less solid waste and fewer atmospheric emissions, and helps to preserve natural resources and landfill space. In addition, the most recent information about the recycling of fibers into various grades of paper and board, the control of stickies, and the effects of recycled fiber on paper machines are also covered. Recycling technologies have been improved in recent years due to advances in pulping, flotation deinking, and cleaning/screening, resulting in the quality of paper made from secondary fibers remarkably approaching that of virgin paper. - Covers all aspects of recycling technologies in great depth - Offers up-to-date authoritative information and cites many mills experiences and pertinent research - Examines the use of biotech methods for deinking, refining, improving drainage, and stickies control - Includes new case studies on paper recycling

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Page Count

396

Publisher

Elsevier

Published Date

ISBN 10

0443238057

ISBN 13

9780443238055

Book's by Pratima Sinha

Cancer Immunotherapy

Cancer Immunotherapy

Biobased Polymers

Biobased Polymers

Karma and Creativity

Karma and Creativity

Developments and Applications of Enzymes From Thermophilic Microorganisms

Developments and Applications of Enzymes From Thermophilic Microorganisms

Biotechnology of Terpenoid Production from Microbial Cell Factories

Biotechnology of Terpenoid Production from Microbial Cell Factories

Microbial Xylanolytic Enzymes

Microbial Xylanolytic Enzymes

Carbon Fiber

Carbon Fiber

Single Cell Protein Production from Lignocellulosic Biomass

Single Cell Protein Production from Lignocellulosic Biomass

Cellulases in the Biofuel Industry

Cellulases in the Biofuel Industry

Microorganisms and enzymes for lignocellulosic biorefineries

Microorganisms and enzymes for lignocellulosic biorefineries

Recycling and Deinking of Recovered Paper

Recycling and Deinking of Recovered Paper

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