In this stunning work of contemporary fiction, Chevalier has succeeded in illuminating one of the unspeakable tragedies of our age: the exploitation of illness. Rendering the depravity and misfeasance of our modern-day temples of medicine with scholarly aplomb, the gripping narrative in Sarcophagus chronicles the journey of an inspired physician and an intrepid biophysicist as they strive against all odds to develop the world's first effective targeted, injectable gene delivery system-the coveted holy grail of genetic medicine. It is a time in history when terminal cancer patients languish on the chain while medical institutions, academic research centers, and giant pharmaceutical companies struggle in unison against the emerging tide of genetic medicine in a misguided effort to maintain the authority and applications of their loathsome poisonous treatments. Written with the passion of a patient advocate and the omniscience of an astute insider, and set against the bleak and timely backdrop of clinical pathos, Sarcophagus is a compelling journey of discovery and descent into the netherworld of modern medicine as it stands poised at the threshold of history.
An exploration of how codes—both cipher and aesthetic—have come to exist in history from Pythagoras through the Knights Templar to Turing and more. Did the Masons encode messages in walls—and even in the street plan of Washington, D.C.? Does the Hebrew Bible conceal hidden mysteries? Ingenious methods for encoding secrets have taken many amazing turns through the ages, from the military signals the Romans flashed from hilltop to hilltop, to the computer codes that guard your cash at the ATM. Pierre Berloquin, one of France’s leading puzzle book authors, takes you on a tour of them all in a book full of astonishing historical insights. With more than 150 brain-teasing problems for readers to solve for themselves, this is a journey beyond the gee-whiz and deep into the how-to of codes, ciphers, and other secret communication systems.
The global financial crisis triggered severe shocks for developing countries, whose embrace of greater commercial and financial openness has increased their exposure to external shocks, both real and financial. This new edition of Development Macroeconomics has been fully revised to address the more open and less stable environment in which developing countries operate today. Describing the latest advances in this rapidly changing field, the book features expanded coverage of public debt and the management of capital inflows as well as new material on fiscal discipline, monetary policy regimes, currency, banking and sovereign debt crises, currency unions, and the choice of an exchange-rate regime. A new chapter on dynamic stochastic general equilibrium (DSGE) models with financial frictions has been added to reflect how the financial crisis has reshaped our thinking on the role of such frictions in generating and propagating real and financial shocks. The book also discusses the role of macroprudential regulation, both independently and through its interactions with monetary policy, in preserving financial and macroeconomic stability. Now in its fourth edition, Development Macroeconomics remains the definitive textbook on the macroeconomics of developing countries. The most authoritative book on the subject—now fully revised and expanded Features new material on fiscal discipline, monetary policy regimes, currency, banking and sovereign debt crises, and much more Comes with online supplements on informal financial markets, stabilization programs, the solution of DSGE models with financial frictions, and exchange rate crises
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