Philippe Derreumaux's Books

Alzheimer's Disease

Insights Into Low Molecular Weight and Cytotoxic Aggregates from in Vitro and Computer Experiments - Molecular Basis of Amyloid-Beta Protein Aggregation and Fibril Formation

By: Philippe Derreumaux

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Alzheimer's Disease

Insights Into Low Molecular Weight and Cytotoxic Aggregates from in Vitro and Computer Experiments - Molecular Basis of Amyloid-Beta Protein Aggregation and Fibril Formation

By: Philippe Derreumaux

Alzheimer's disease is the most common form of senile dementia, affecting more than 24 million people worldwide. It is characterised pathologically by abnormally high levels of neurofibrillary tangles resulting from the accumulation of tau protein in dead and dying neurons, and by elevated numbers of senile plaques in the cortex and hippocampus of the brain. The major component of senile plaques is a small protein of 39OCo43 amino acids called amyloid-? (A?). Thus far, no treatment has been shown to slow the progression of sporadic and familial Alzheimer's disease.A large body of evidence points, however, to the early A?-formed oligomers as the primary toxic species in Alzheimer's disease. A powerful strategy for developing pharmaceutical treatments against Alzheimer's is to elucidate the pathways of oligomer formation and determine the structures of the toxic aggregates.This book provides a panoramic view across recent in vitro and in vivo studies along with state-of-the-art computer simulations, designed to increase the readers' understanding of A? oligomerisation and fibril formation. At the same time, the book delves into the pathogenesis of familial and sporadic Alzheimer's disease at the atomic level of detail.Written by leading authors in their respective fields, this book will be valuable to all scientists working on Alzheimer's disease.

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Page Count

465

Publisher

World Scientific

Published Date

ISBN 10

1848167555

ISBN 13

9781848167551

Alzheimer's Disease

Insights Into Low Molecular Weight and Cytotoxic Aggregates from in Vitro and Computer Experiments - Molecular Basis of Amyloid-Beta Protein Aggregation and Fibril Formation

By: Philippe Derreumaux

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Alzheimer's Disease

Insights Into Low Molecular Weight and Cytotoxic Aggregates from in Vitro and Computer Experiments - Molecular Basis of Amyloid-Beta Protein Aggregation and Fibril Formation

By: Philippe Derreumaux

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465

Publisher

World Scientific

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ISBN 10

1848167555

ISBN 13

9781848167551

Disturbance

Surviving Charlie Hebdo

By: Philippe Lançon

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Disturbance

Surviving Charlie Hebdo

By: Philippe Lançon

In this Prix Femina–winning memoir, a writer at the French satirical newspaper Charlie Hebdo recounts surviving the deadly terror attack on their office. On January 7, 2015, two terrorists claiming allegiance to ISIS attack the Paris office of the satirical weekly Charlie Hebdo. The event causes untold pain to the victims and their families, prompts a global solidarity movement, and ignites a fierce debate over press freedoms and the role of satire today. Philippe Lançon, a journalist, author, and a weekly contributor to Charlie Hebdo is gravely wounded in the attack—an experience that upends his relationship to the world. As Lançon attempts to reconstruct his life on the page, he rereads Proust, Thomas Mann, Kafka, and others in search of guidance. It is a year before he can return to writing, a year in which he learns to work through his experiences and their aftermath. Disturbance is not an essay on terrorism nor is it a witness’s account of Charlie Hebdo. It is an honest, intimate account of a man seeking to put his life back together after it has been torn apart. “A powerful and deeply civilized memoir.” —The New York Times

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Page Count

404

Publisher

Europa Editions

Published Date

ISBN 10

1609455576

ISBN 13

9781609455576

Book's by Philippe Derreumaux

Alzheimer's Disease

Alzheimer's Disease

Alzheimer's Disease

Alzheimer's Disease

Disturbance

Disturbance

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