Becoming German tells the intriguing story of the largest and earliest mass movement of German-speaking immigrants to America. The so-called Palatine migration of 1709 began in the western part of the Holy Roman Empire, where perhaps as many as thirty thousand people left their homes, lured by rumors that Britain's Queen Anne would give them free passage overseas and land in America. They journeyed down the Rhine and eventually made their way to London, where they settled in refugee camps. The rumors of free passage and land proved false, but, in an attempt to clear the camps, the British government finally agreed to send about three thousand of the immigrants to New York in exchange for several years of labor. After their arrival, the Palatines refused to work as indentured servants and eventually settled in autonomous German communities near the Iroquois of central New York.Becoming German tracks the Palatines' travels from Germany to London to New York City and into the frontier areas of New York. Philip Otterness demonstrates that the Palatines cannot be viewed as a cohesive "German" group until after their arrival in America; indeed, they came from dozens of distinct principalities in the Holy Roman Empire. It was only in refusing to assimilate to British colonial culture—instead maintaining separate German-speaking communities and mixing on friendly terms with Native American neighbors—that the Palatines became German in America.
Publisher's Note: Products purchased from 3rd Party sellers are not guaranteed by the Publisher for quality, authenticity, or access to any online entitlements included with the product. Substantially updated with more illustrations and brand-new chapters that reflect the growth and advances in the field, this latest edition of Acute Care Surgery features an editorial board drawn from the ranks of trauma surgery, emergency surgery, and critical care surgery. A comprehensive, updated, and timely overview of this fledgling specialty!
As Ben Goldacre’s Guardian Bad Science column debunks popular scientific myths, this book aims to do the same for education myths and unjustified claims.
gricultural science policy in the United States has profoundly affected the growth and development of agriculture worldwide, not just in the A United States. Over the past 150 years, and especially over the second th half of the 20 Century, public investments in agricultural R&D in the United States grew faster than the value of agricultural production. Public spending on agricultural science grew similarly in other more-developed countries, and c- lectively these efforts, along with private spending, spurred agricultural prod- tivity growth in rich and poor nations alike. The value of this investment is seldom fully appreciated. The resulting p- ductivity improvements have released labor and other resources for alternative uses—in 1900, 29. 2 million Americans (39 percent of the population) were - rectly engaged in farming compared with just 2. 9 million (1. 1 percent) today— while making food and fiber more abundant and cheaper. The benefits are not confined to Americans. U. S. agricultural science has contributed with others to growth in agricultural productivity in many other countries as well as the Un- ed States. The world’s population more than doubled from around 3 billion in 1961 to 6. 54 billion in 2006 (U. S. Census Bureau 2009). Over the same period, production of important grain crops (including maize, wheat and rice) almost trebled, such that global per capita grain production was 18 percent higher in 2006.
It has been over 50 years since Hans Selye formulated his concept of stress. This came after the isolation of epinephrine and norepinephrine and after the sympathetic system was associated with Walter Cannon's "fight or flight" response. The intervening years have witnessed a number of dis coveries that have furthered our understanding of the mechanisms of the stress response. The isolation, identification and manufacture of gluco corticoids, the identification and synthesis of ACTH and vasopressin, and the demonstration of hypothalamic regulation of ACTH secretion were pivotal discoveries. The recent identification and synthesis of CRR by Willie Vale and his colleagues gave new impetus to stress research. Several new concepts of stress have developed as a result of advances in bench research. These include the concept of an integrated "stress sys tem", the realization that there are bi-directional effects between stress and the immune system, the suggestion that a number of common psychiatric disorders represent dysregulation of systems responding to stress, and the epidemiologic association of stress with the major scourges of humanity.
Of the multitude of toxins known and the enormous variety of effects they cause, of particular interest are those that influence signal transduction. Intercellular communication by chemical signals is essential for the functioning of multicellular organisms. Many toxins exert their biological effects by interfering with the signal transduction initiated by these chemicals (hormones, transmitters, growth factors, and other mediators). Up-to-date information is provided by outstanding experts, who discuss the molecular mechanisms involved in the action of many toxins, as well as the use of toxins as informative tools with which to study signal transduction and their potential therapeutic usage. This volume contains useful information for the experimentalist interested in toxins or in signal transduction, as well as for the reader interested in gaining a comprehensive overview of the field. The Cellular and Molecular Mechanisms of Toxin Action series will include monographs on signal transduction, secretory systems, cytoskeleton, selective neurotoxicity of natural, recombinant and chimeric toxins giving a broader emphasis on the mechanism of action, structure-function relationship, and use of toxins as research tools and their therapeutic applications.
Knowledge of transcription has moved forward at a furious pace over recent years, and an understanding of the processes involved in gene regulation and expression has become an essential element in biochemistry, genome biology, molecular biology and molecular genetics. In this timely book, the authors present an accessible, yet comprehensive, coverage suitable for students at a senior undergraduate level, and for postgraduates needing an overview of the current state of play. It covers a number of pertinent examples of transcription systems for eukaryotes and prokaryotes, indicates methods for studying transcription, and surveys the whole topic of transcription from many perspectives.
Cross-Cultural Practice with Couples and Families prepares you for the ways that cultural realities can affect your social work practice with both couples and families. You will gain in-depth exposure to a variety of cultural values and perspectives and learn to identify similarities and differences between and among different ethnic families. This will lead you to a deeper, more thorough understanding of the roles, dynamics, and particular challenges of social work, both current and historical.From Cross-Cultural Practice with Couples and Families, you will learn how to use the religious history, family values, rituals, and community in attaining positive outcomes in treatment. Placing value on diversity in families, supporting ethnic differences, and recognizing the strength and resiliency of modern-day families will become the cornerstones of your more effective and sensitive social work practice. The authors, who come with firsthand experience, provide you with specific models and approaches for working with families and couples of different backgrounds. They also offer you insight on: treatment implications for interracial couples the components of healthy marriages domestic violence from various cultural perspectives the Native American family circle cross-cultural considerations in family preservation the realities of racism in the worker-client relationshipCross-Cultural Practice with Couples and Families is an excellent resource for graduate students, faculty, and practitioners alike! When ideas and interventions become more complex, the authors guide you through them step-by-step to make implementation easy and practical. Nowhere else will you find such a reader-friendly form that makes the role of culture in therapy and its influence on structure, communication, dynamics, process, and interventions within couple and family systems so astonishingly clear!
Put the world's most well-known kidney reference to work in your practice with the 11th Edition of Brenner & Rector's The Kidney. This two-volume masterwork provides expert, well-illustrated information on everything from basic science and pathophysiology to clinical best practices. Addressing current issues such as new therapies for cardiorenal syndrome, the increased importance of supportive or palliative care in advanced chronic kidney disease, increasing live kidney donation in transplants, and emerging discoveries in stem cell and kidney regeneration, this revised edition prepares you for any clinical challenge you may encounter. - Extensively updated chapters throughout, providing the latest scientific and clinical information from authorities in their respective fields. - Lifespan coverage of kidney health and disease from pre-conception through fetal and infant health, childhood, adulthood, and old age. - Discussions of today's hot topics, including the global increase in acute kidney injury, chronic kidney disease of unknown etiology, cardiovascular disease and renal disease, and global initiatives for alternatives in areas with limited facilities for dialysis or transplant. - New Key Points that represent either new findings or "pearls" of information that are not widely known or understood. - New Clinical Relevance boxes that highlight the information you must know during a patient visit, such as pertinent physiology or pathophysiology. - Hundreds of full-color, high-quality photographs as well as carefully chosen figures, algorithms, and tables that illustrate essential concepts, nuances of clinical presentation and technique, and clinical decision making. - A new editor who is a world-renowned expert in global health and nephrology care in underserved populations, Dr. Valerie A. Luyckx from University of Zürich. - Board review-style questions to help you prepare for certification or recertification. - Enhanced eBook version included with purchase, which allows you to access all of the text, figures, and references from the book on a variety of devices
Ending Terrorism in Italy analyses processes of disengagement from terrorism, as well as the connected issues of reconciliation, truth and justice. It examines in a critical and original way how terrorism came to an end in Italy (Part I), and the legacy it has left behind (Part II). The book interrogates a wide array of published memoirs and a considerable number of new face-to-face interviews with both former terrorists and first and second generation victims In the last two decades, and especially in recent years, former extreme-right terrorists in Italy have started to talk about their past involvement in terrorist violence, including, for the first time, acts of violence which have for decades been considered taboo, that is to say, bomb attacks against innocent civilians. These narratives add to the perspectives offered by members of left-wing terrorist groups, such as the Red Brigades and Prima Linea. Surprisingly, these narratives have not been systematically examined, yet they form a unique and extremely rich source of first-hand testimony, providing invaluable insights into processes of youth radicalization and de-radicalization, the social re-integration of ex-terrorists, as well as personal and collective healing. Even less attention has been paid to the victims’ narratives or stories. Indeed, the views and activities of the victims and their associations have been seriously neglected in the scholarly literature on terrorism, not just in Italy, but elsewhere in Europe. The book therefore examines the perspectives of the victims and relatives of victims of terrorism, who over the years have formed dedicated associations and campaigned relentlessly to obtain justice through the courts, with little or no support from the state and, especially in the case of the bombing massacres, with increasing awareness that the state played a role in thwarting the course of justice. Ending Terrorism in Italy will be of interest to historians, social scientists and policy makers as well as students of political violence and post-conflict resolution. .
The third edition has been revised and updated to include information on micro RNAs, RNA inhibition, functional genomics, proteomics, imaging, stem cells and bioinformatics.
This Volume 5 in a continuing series represents the compilation of papers presented at the International Symposium on Analytical Calorimetry as part of the 185th National Meeting of the American Chemical Society, Seattle, Washington, March 20-25th. 1983. A much broader variety of topics are covered than in pre vious volumes, due to the growth in the field of Thermal Analysis. Specific topics covering such techniques as differential scanning calorimetry, combined thermogravimetric procedures, dynamic mechan ical analysis and a variety of novel kinetic analyses are covered. A wide range of material types are included in this volume such as polymers (alloys, blends and composites), fossil fuels, biological products, liquid crystals and inorganic materials. The co-editors of this volume would like to thank all the contributors for their efforts in conforming to the manuscript requirements, and for being prompt in the preparation. We would also like to thank those who presided over sessions during the course of the symposium; Professor Anselm C. Griffin, Professor Roger S. Porter and Dr. Edith A. Turi.
Overcome the toughest clinical challenges in nephrology with the new 9th edition of Brenner/Rector’s The Kidney! A brand-new editorial team of Drs. Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S. L. Yu, and Barry M. Brenner,, together with a diverse list of international contributors bring you the latest knowledge and best practices on every front in nephrology worldwide. Brand-new sections on Global Considerations in Nephrology and Pediatric Nephrology, as well as new chapters on recent clinical trials, cardiovascular and renal risk prediction in chronic kidney disease, identification of genetic causes of kidney disease, and many others, keep you at the forefront of this rapidly growing, ever-changing specialty. Brenner/Rector remains the go-to resource for practicing and training nephrologists and internists who wish to master basic science, pathophysiology, and clinical best practices. Broaden your knowledge base with expert, dependable, comprehensive answers for every stage of your career from the most comprehensive, definitive clinical reference in the field! Prepare for certification or recertification with a review of the basic science that underpins clinical nephrology as well as a comprehensive selection of the most important bibliographical sources in nephrology. Visually grasp and better understand critical information with the aid of over 700 full-color high-quality photographs as well as carefully chosen figures, algorithms, and tables to illustrate essential concepts, nuances of clinical presentation and technique, and decision making. Get internationally diverse, trusted guidance and perspectives from a team of well-respected global contributors, all of whom are at the top and the cutting edge of your field. A new editorial team headed by Dr. Taal and hand-picked by Dr. Brenner ensures the ongoing adherence to previous standards of excellence. Access information quickly thanks to a new, reorganized format and supplemental figures, tables, additional references, and expanded discussions. Keep current with the rapid development of care and research worldwide. A new section, "Global Considerations", focuses on regions outside Europe and North America. Leading experts from Latin America, Africa, Near and Middle East, Indian Subcontinent, Far East, Oceania and Australia present their expert insights into specific conditions, as well as progress and challenges in the development of the specialty. Improve therapy and outcomes for children with renal disease. New to this edition, "Pediatric Nephrology" addresses renal pathologies that usually present in childhood and covers topics such as Maturation of Kidney Structure and Function; Fluid; Electrolyte and Acid-Base Disorders in Children; Diseases of the Kidney and Urinary Tract in Children; Dialysis in Children; and Kidney Transplantation in Children. Stay up to date with all the latest clinical information including recent clinical trials, genetic causes of kidney disease, and cardiovascular and renal risk prediction in chronic kidney disease.
This pre-eminent work has developed over six editions in response to man's attempts to climb higher and higher unaided, and to spend more time at altitude for both work and recreation. Building on this established reputation, the new and highly experienced authors provide a fully revised and updated text that will help doctors continue to improve the health and safety of all people who visit, live or work in the cold, thin air of high mountains. The sixth edition remains invaluable for any doctor accompanying an expedition or advising patients on a visit to altitude, those specialising in illness and accidents in high places, and for physicians and physiologists who study our dependence on oxygen and the adaptation of the body to altitude.
Take someone with superior intelligence, unusual strength, perfect vision, catlike reflexes, exceptional marksmanship, and nerves of steel – and you just might have what it takes. The fighter pilot had total control of an airborne vehicle traveling hundreds of miles an hour, and was capable of leaving a devastating path of destruction in his wake. Navigating with brains and stamina, making life-or-death decisions in the blink of an eye, these unique heroes succeeded or failed by their skill and wit. And although their planes have changed over the years – from World War I’s precarious contraptions made of wood, wire, and cloth; to the metal monsters of the second World War, and finally to sleek, computerized birds able to cruise at speeds that exceed Mach 1 – fighter pilots still must out-think and out-fly opponents in a one-on-one contest where everything is at stake. Profusely illustrated throughout with action photos, paintings, memorabilia and mementoes, Lone Eagle is a vivid volume recalling the thrill of flying Spitfires, Phantoms, Zeroes, and other fighter planes throughout aviation history. Through engaging personal stories and remembrances, this book examines the combat missions and evolution of tactics gathered over the last 70 years, where every hour of every day was an unforgettable and marvelous experience.
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