In the intervening years since this book was published in 1981, the field of optimization has been exceptionally lively. This fertility has involved not only progress in theory, but also faster numerical algorithms and extensions into unexpected or previously unknown areas such as semidefinite programming. Despite these changes, many of the important principles and much of the intuition can be found in this Classics version of Practical Optimization. This book provides model algorithms and pseudocode, useful tools for users who prefer to write their own code as well as for those who want to understand externally provided code. It presents algorithms in a step-by-step format, revealing the overall structure of the underlying procedures and thereby allowing a high-level perspective on the fundamental differences. And it contains a wealth of techniques and strategies that are well suited for optimization in the twenty-first century, and particularly in the now-flourishing fields of data science, big data, and machine learning. Practical Optimization is appropriate for advanced undergraduates, graduate students, and researchers interested in methods for solving optimization problems.
This important book traces the history of genetics and genomics policy in Britain. Detailing the scientific, political, and economic factors that have informed policy and the development of new health services, the book highlights the particular importance of the field of Public Health Genomics. Although focused primarily on events in Britain, the book reveals a number of globally applicable lessons. The authors explain how and why Public Health Genomics developed and the ways in which genetics and genomics have come to have a central place in many important health debates. Consideration of their ethical, social, and legal implications and ensuring that new services that are equitable, appropriate, and well-targeted will be central to effective health planning and policymaking in future. The book features: Interviews with leading individuals who were intimately involved in the development of genetics and genomics policy and Public Health Genomics Insights from experts who participated in a pair of 'witness seminars' Historical analysis exploiting a wide range of primary sources Written in a clear and accessible style, this book will be of interest to those involved in the research and practice of genetics, genomics, bioethics, and population health, but also to NHS staff, policymakers, politicians, and the public. It will also be valuable supplementary reading for students of the History of Medicine and Health, Public Health, and Biomedical Sciences.
This classic volume covers the fundamentals of two closely related topics: linear systems (linear equations and least-squares) and linear programming (optimizing a linear function subject to linear constraints). For each problem class, stable and efficient numerical algorithms intended for a finite-precision environment are derived and analyzed. While linear algebra and optimization have made huge advances since this book first appeared in 1991, the fundamental principles have not changed. These topics were rarely taught with a unified perspective, and, somewhat surprisingly, this remains true 30 years later. As a result, some of the material in this book can be difficult to find elsewhere—in particular, techniques for updating the LU factorization, descriptions of the simplex method applied to all-inequality form, and the analysis of what happens when using an approximate inverse to solve Ax=b. Numerical Linear Algebra and Optimization is primarily a reference for students who want to learn about numerical techniques for solving linear systems and/or linear programming using the simplex method; however, Chapters 6, 7, and 8 can be used as the text for an upper-division course on linear least squares and linear programming. Understanding is enhanced by numerous exercises.
High Risk Pregnancy examines the full range of challenges in general obstetrics, medical complications of pregnancy, prenatal diagnosis, fetal disease, and management of labor and delivery. Drs. David James, Philip J. Steer, Carl P. Weiner, Bernard Gonik, Caroline Crowther, and Stephen Robson present an evidence-based approach to the available management options, equipping you with the most appropriate strategy for each patient. This comprehensive reference features the fully searchable text online at www.expertconsult.com, as well as more than 100 videos of imaging and monitoring. giving you easy access to the resources you need to manage high risk pregnancies. Prepare for clinical challenges and save time in addressing them thanks to expert advice on treatment options from international contributors. Find and apply the information you need quickly and easily through a consistent organization and at-a-glance summary boxes that discuss evidence-based management options. Access the fully searchable text online at www.expertconsult.com, along with links to Medline. View over 140 videos of detailed fetal imaging and monitoring that aid in diagnoses. Tap into recent developments in treatment and management in four new chapters—Global Maternal & Perinatal Health Issues; Recurrent Pregnancy Loss; Surveillance of the Fetus and its Indications; and Training for Obstetric Emergencies. Apply new evidence-based management options to treat genetic and constitutional factors leading to a high-risk pregnancy (such as diabetes, obesity, hypertension, and cardiac disease) through new and expanded coverage of these increasingly common presentations. Reference pregnancy-relevant laboratory values with an updated and comprehensive appendix on "Normal Values in Pregnancy." Effectively manage patients newly diagnosed with hematologic and immunologic malignancies, and explore the available drug options. Confirm your diagnoses with greater confidence thanks to full-color images throughout the text.
Almost 500 species are covered in this book, with detailed accounts and maps of their distribution, habitat, nesting, movements, taxonomy (including subspecies), status, historical changes, and conservation outlook.
Sport and Exercise Science: An Introduction provides a broad-based foundation in the major areas that underpin the scientific study of sport and exercise science, thus helping undergraduate students to develop a sound understanding of human anatomy, physiology, nutrition, metabolism, biomechanics and psychology related to sport, exercise and health. It includes a range of useful features in every chapter, including clear explanations of key concepts, colour diagrams and photographs, activities and summaries to reinforce understanding, and on-line support materials for lecturers such as question and image banks. This is the essential companion text for any student studying sport and exercise science at degree level.
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