This book discusses biochemical adaptation to environments from freezing polar oceans to boiling hot springs, and under hydrostatic pressures up to 1,000 times that at sea level. Originally published in 1984. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Surviving Hypoxia: Mechanisms of Control and Adaptation is a synthesis of findings and thoughts concerning hypoxia. The thermodynamics of hypoxia are discussed in detail, including acid-base balance and self-pollution resulting from the accumulation of anaerobic end-products. The book focuses on descriptions and discussions of common facets, contrasting solutions in a variety of physiological hypoxia defense strategies, including those shown by plants, invertebrates, and vertebrates. Special treatment is given to the distinctive problems that hypoxia presents to vulnerable organs such as the kidney, liver, and brain. It also addresses pathological events in addition to protective mechanisms. Clinical implications of basic research are examined in the book, which provides new insights into underlying pathological processes occuring in hypoxic-induced organ failure and indicates new paths for successful clinical intervention. Surviving Hypoxia: Mechanisms of Control and Adaptation is an excellent reference for all researchers interested in the physiological effects of hypoxia, underlying pathological events, and protective mechanisms.
First published in 1994, this book explores the paradigm of muscles as molecular and metabolic machines in which all structures and functions are exquisitely integrated and matched to each other. The analysis begins with a standard reductionist approach-reviewing the integrated machine parts. The key working components of the complete muscle machine are proteins (soluble, organelle, or membrane localized), and a conservative count indicates that today more than 100 such machine parts are known, essentially all occurring as cell specific isoforms. Random assortment of these machine parts or protein isoforms could generate an astronomical number of "muscle machines" and an equally enormous number of muscle fiber types. The question is, why aren't such large numbers ever seen? To attack this problem, the reductionist approach is complemented with an integrationist/adaptational one. Evidence is presented that the more highly specialized the muscle type, the further one moves from the above extreme; in the most highly specialized muscles, typically only one fiber type is found. It is argued that instead of random assortment of isoforms or machine parts, only specific and often unique combinations can work in appropriate fashion. A few established examples of this fundamental principle are reviewed, but emphasis is placed on the fact that we know dreadfully little about why this is so and what kinds of further studies are needed. The issue of why the very large numbers of fiber types theoretically possible are never even approximately realized has never before been addressed. Indeed, it is rarely recognized. Muscles as Molecular and Metabolic Machines is the first work of its kind on the subject.
A comprehensive and beautifully illustrated overview to the birds of Maine The first comprehensive overview of Maine’s incredibly rich birdlife in more than seven decades, Birds of Maine is a detailed account of all 464 species recorded in the Pine Tree State. It is also a thoroughly researched, accessible portrait of a region undergoing rapid changes, with southern birds pushing north, northern birds expanding south, and once-absent natives like Atlantic Puffins brought back by innovative conservation techniques pioneered in Maine. Written by the late Peter Vickery in cooperation with a team of leading ornithologists, this guide offers a detailed look at the state’s dynamic avifauna—from the Wild Turkey to the Arctic Tern—with information on migration patterns and timing, current status and changes in bird abundance and distribution, and how Maine's geography and shifting climate mold its birdlife. It delves into the conservation status for Maine's birds, as well as the state's unusually textured ornithological history, involving such famous names as John James Audubon and Theodore Roosevelt, and home-grown experts like Cordelia Stanwood and Ralph Palmer. Sidebars explore diverse topics, including the Old Sow whirlpool that draws multitudes of seabirds and the famed Monhegan Island, a mecca for migrant birds. Gorgeously illustrated with watercolors by Lars Jonsson and scores of line drawings by Barry Van Dusen, Birds of Maine is a remarkable guide that birders will rely on for decades to come. Copublished with the Nuttall Ornithological Club
Suitable for graduates and undergraduates in environmental biology, comparative physiology, and marine biology, this text lays out the principles of mechanistic comparative physiology in an ecological and evolutionary context. This text lays out the principles of mechanistic comparative physiology in an ecological and evolutionary context. The subject of evolutionary physiology has been advancing considerably and this book will bring readers up to date on a number of new techniques, ideas and data. Topics include NMR spectroscopy and molecular biology, evolution and adaptation, phylogenetically-based analytical techniques and more.
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