Teaching the science and the technology of programming as a unified discipline that shows the deep relationships between programming paradigms. This innovative text presents computer programming as a unified discipline in a way that is both practical and scientifically sound. The book focuses on techniques of lasting value and explains them precisely in terms of a simple abstract machine. The book presents all major programming paradigms in a uniform framework that shows their deep relationships and how and where to use them together. After an introduction to programming concepts, the book presents both well-known and lesser-known computation models ("programming paradigms"). Each model has its own set of techniques and each is included on the basis of its usefulness in practice. The general models include declarative programming, declarative concurrency, message-passing concurrency, explicit state, object-oriented programming, shared-state concurrency, and relational programming. Specialized models include graphical user interface programming, distributed programming, and constraint programming. Each model is based on its kernel language—a simple core language that consists of a small number of programmer-significant elements. The kernel languages are introduced progressively, adding concepts one by one, thus showing the deep relationships between different models. The kernel languages are defined precisely in terms of a simple abstract machine. Because a wide variety of languages and programming paradigms can be modeled by a small set of closely related kernel languages, this approach allows programmer and student to grasp the underlying unity of programming. The book has many program fragments and exercises, all of which can be run on the Mozart Programming System, an Open Source software package that features an interactive incremental development environment.
Teaching the science and the technology of programming as a unified discipline that shows the deep relationships between programming paradigms. This innovative text presents computer programming as a unified discipline in a way that is both practical and scientifically sound. The book focuses on techniques of lasting value and explains them precisely in terms of a simple abstract machine. The book presents all major programming paradigms in a uniform framework that shows their deep relationships and how and where to use them together. After an introduction to programming concepts, the book presents both well-known and lesser-known computation models ("programming paradigms"). Each model has its own set of techniques and each is included on the basis of its usefulness in practice. The general models include declarative programming, declarative concurrency, message-passing concurrency, explicit state, object-oriented programming, shared-state concurrency, and relational programming. Specialized models include graphical user interface programming, distributed programming, and constraint programming. Each model is based on its kernel language—a simple core language that consists of a small number of programmer-significant elements. The kernel languages are introduced progressively, adding concepts one by one, thus showing the deep relationships between different models. The kernel languages are defined precisely in terms of a simple abstract machine. Because a wide variety of languages and programming paradigms can be modeled by a small set of closely related kernel languages, this approach allows programmer and student to grasp the underlying unity of programming. The book has many program fragments and exercises, all of which can be run on the Mozart Programming System, an Open Source software package that features an interactive incremental development environment.
This major, revisionist reference work explains for the first time how the Stationers' Company acquired both a charter and a nationwide monopoly of printing. In the most detailed and comprehensive investigation of the London book trade in any period, Peter Blayney systematically documents the story from 1501, when printing first established permanent roots inside the City boundaries, until the Stationers' Company was incorporated by royal charter in 1557. Having exhaustively re-examined original sources and scoured numerous archives unexplored by others in the field, Blayney radically revises accepted beliefs about such matters as the scale of native production versus importation, privileges and patents, and the regulation of printing by the Church, Crown and City. His persistent focus on individuals - most notably the families, rivals and successors of Richard Pynson, John Rastell and Robert Redman - keeps this study firmly grounded in the vivid lives and careers of early Tudor Londoners.
In this Completely Revised and Extended Edition with a significantly enhanced content, all Chapters have been updated considering relevant literature and recent developments until 2016 together with application oriented examples with a focus on Industrial Biocatalysis. Newly treated topics comprise among others systems metabolic engineering approaches, metagenome screening, new tools for pathway engineering, and de-novo computational design as actual research areas in biocatalysis. Information about different aspects of RNA technologies, and completely new Chapters on 'Fluorescent Proteins' and 'Biocatalysis and Nanotechnology' are also included.
Paradigms of AI Programming is the first text to teach advanced Common Lisp techniques in the context of building major AI systems. By reconstructing authentic, complex AI programs using state-of-the-art Common Lisp, the book teaches students and professionals how to build and debug robust practical programs, while demonstrating superior programming style and important AI concepts. The author strongly emphasizes the practical performance issues involved in writing real working programs of significant size. Chapters on troubleshooting and efficiency are included, along with a discussion of the fundamentals of object-oriented programming and a description of the main CLOS functions. This volume is an excellent text for a course on AI programming, a useful supplement for general AI courses and an indispensable reference for the professional programmer.
Now in a newly updated and revised edition, this timely resource provides you with complete and current details on the theory, design, and applications of wireless antennas for on-body electronic systems. The Second Edition offers readers brand new material on advances in physical phantom design and production, recent developments in simulation methods and numerical phantoms, descriptions of methods for simulation of moving bodies, and the use of the body as a transmission channel. You also find a completely revised chapter on channel characterization and antenna design at microwave frequencies. This cutting-edge volume brings you the state-of-the-art in existing applications like Bluetooth headsets together with detailed treatment of techniques, tools, and challenges in developing on-body antennas for an array of medical, emergency response, law enforcement, personal entertainment, and military applications on the horizon. The book briefs you on energy propagation around and into the body and how to estimate performance of on-body wireless links, and then dives into the nuts-and-bolts of designing antenna systems that deliver the goods. It covers on-body communication channels at microwave frequency bands and at low frequency bands, as well as ultra wideband systems for WPANs and WBANs. You get details on body-centric UWB antennas and channels, as well as advances in wearable mobile, EBG, and smart fabricù antennas for cellular and WLAN communications. Chapters on telemedicine applications, such as remote diagnoses, and implantable medical devices cover crucial propagation issues and other obstacles that need to be addressed. Rounding out the coverage is a section on antenna design for body-sensor networks and their emerging military and space applications. Packed with hands-on guidance from noted experts, this volume will be indispensable for your efforts in designing and improving body-centric communication systems.
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
This issue provides an overview of anatomy for the practicing radiologist using MR. Neuroanatomy is covered in separate articles on the brain, neck, spine, and skull base. Body imaging is reviewed in articles on chest, abdomen, breast, and pelvis, and finally, the musculoskeletal system is thoroughly displayed by articles on shoulder, elbow, wrist and hand, knee, and ankle and foot. Long bones of the upper and lower extremities are reviewed in separate articles as well.
How to build winning digital products today? In this book, the authors explore what it takes to build winning digital products today. They focus on the idea that one should stop building software, and build digital services instead, effectively combining Hyperscale and Microcare: the ability to establish an intimate relationship with each and every of your thousands of users. The authors discuss the capabilities and processes you need to build such digital services. They zoom in on the kinds of assets you need to develop, and that will greatly influence the valuation, all supported with practical advice and real world examples. Discover a guide with practical advices and real world examples to build digital services and create relashionship with users. EXTRAIT As any cookbook, this work contains recipes, ingredient descriptions and best practices. To us – both amateur chefs – a flaw of most kitchen guides is the focus on lists and the weak insight they bring about the basic mechanisms. The process behind a tricky recipe like sauce Hollandaise is an emulsion between an oil and an aqueous component: butter and lemon juice are bound by egg yolk, used as an emulsifier. Digital entrepreneurship (cook) books show the same weakness. They distill guide-lines without linking them to the root mechanisms in digital. We base our recipes on these mechanisms. To explain them, we tell the story through the arrival of three digital paradoxes. Paradoxes intrigue, trigger curiosity, and animate a discussion between peers. That’s why they are excellent starting material to reason about a world in change. À PROPOS DE L'AUTEUR Peter Verhasselt coaches technology companies in optimizing their Product Management, Business Plan and Go-to-Market strategy. Before joining Sirris, Peter worked for industrial companies in Sales and Product Management, Field Service and R&D. Peter has degrees in Engineering, Law, Economics and Management. Nick Boucart is a mentor, coach and regular speaker on topics like Cloud, SaaS, Data Driven Product Management and Software Engineering. He’s an interim CTO for a number of startups. Prior to working at Sirris, Nick was a software engineer at LMS International and EMC.
The latest addition to the popular Teaching Atlas series, this book provides a complete overview of the common and rare manifestations of musculoskeletal disorders and diseases. Internationally recognized authors guide the reader through multi-modality imaging approaches for 130 problems.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
The Birds of Turkey is the first avifauna to document this country's amazing ornithological diversity. Turkey - ornithologically one of the most fascinating countries in the Western Palearctic - lies not only at the crossroads between Europe and Asia, but also at the meeting point of a variety of biomes. The extensive semi-deserts of the Middle East reach their northernmost limit in southeastern Turkey, while the Pontic Mountains, which dominate much of the north of the country, support a principally European fauna, along with near-endemics such as Caucasian Grouse, Green Warbler, Caspian Snowcock and Krüper's Nuthatch. In Central Turkey, huge saline lakes hold colonies of flamingos, pelicans and Pygmy Cormorants, while the surrounding semi-steppe supports populations of Montagu's Harrier, Great Bustard and abundant lakes. The book looks in detail at every species ever reported in the country - breeding birds, passage migrants, winter visitors and vagrants - with a review of status and distribution, accurate distribution maps, and discussions of breeding biology and the latest taxonomic revisions. Introductory chapters provide overviews of Turkey's major biomes and the history or ornithology in the country, and a discussion of future research objections. The book also contains stunning colour photography by a number of leading Turkish ornithologists. Indispensable for anyone interested in the Turkish avifauna, The Birds of Turkey will remain the standard work on this key ornithological region for many years to come.
Among the finest examples of European craftsmanship are the clocks produced for the luxury trade in the eighteenth century. The J. Paul Getty Museum is fortunate to have in its decorative arts collection twenty clocks dating from around 1680 to 1798: eighteen produced in France and two in Germany. They demonstrate the extraordinary workmanship that went into both the design and execution of the cases and the intricate movements by which the clocks operated. In this handsome volume, each clock is pictured and discussed in detail, and each movement diagrammed and described. In addition, biographies of the clockmakers and enamelers are included, as are indexes of the names of the makers, previous owners, and locations.
Artificial intelligence: A Modern Approach, 3e,is ideal for one or two-semester, undergraduate or graduate-level courses in Artificial Intelligence. It is also a valuable resource for computer professionals, linguists, and cognitive scientists interested in artificial intelligence. The revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence.
Malaria causes more death and disease than any other parasitic pathogen known today. This multiauthored text covers the important areas of malaria research, particularly focusing on those sectors which are of clinical importance for the understanding of the disease, the parasite, and its vector. The chapter authors are all leading experts within their own particular fields. The biology and molecular biology of the parasite, the clinical spectrum of the disease, the pathogenesis of malaria, and the immunology and emergence of malaria vaccines are some examples of the scientific spheres that are discussed. The book is suitable as a text for graduate students and clinicians as well as researchers at universities and companies involved in treating or studying infectious diseases.
Who was Anthony Garrett? The murder of a reclusive local man draws DCI Hennessey and DS Yellich into a baffling new case. On a hot summer morning, Miles Law cycles into the village of Millington in the Vale of York, on his way to a few hours’ work as an under gardener at The Grange. But when he arrives, he finds his employer slumped in an armchair in the drawing room, a bullet wound on his forehead. Miles’ employer was a secretive and reclusive man who kept his employees and neighbours at a distance. Who was Anthony Garrett, and who are the three young, identical-looking blonde women who called at the house a few days before his body was discovered? Detective Chief Inspector George Hennessey and Detective Superintendent Somerled Yellich are soon on the hunt for a ruthless and efficient killer...
First Published in 2005. The task of compiling a bibliography of the African slave trade is a difficult one as the literature comprises books, pamphlets and periodical articles in a variety of languages from the sixteenth century to the present day. This title aspires to present a representative selection of the material available and serve as a guide to the main categories of printed material on the subject in western languages. Due to their pre-existing availability and overwhelming quantity, government publications have been kept to a minimum.
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
This fourth edition of Peter Bernath's successful Spectra of Atoms and Molecules is designed to provide advanced undergraduate and graduate students a working knowledge of the vast field of spectroscopy. Also of interest to chemists, physicists, astronomers, atmospheric scientists, and engineers, this volume emphasizes the fundamental principles of spectroscopy with the primary goal of teaching the interpretation of spectra. Features include a presentation of group theory as needed to understand spectroscopy, detailed worked examples and a large number of excellent problems at the end of each chapter. Bernath provides a large number of diagrams and spectra which have been specifically recorded for this book. Molecular symmetry, matrix representation of groups, quantum mechanics, and group theory are among the topics covered; atomic, rotational, vibrational, electronic and Raman spectra are analyzed as well. Bernath's treatment clears the confusing topic of line strengths as needed for quantitative applications. Responding to student requests, the fourth addition features detailed and worked examples in each chapter. This book has also been updated to include the 2018 CODATA revision of physical constants and a large number of corrections and clarifications. New chapters on atmospheric and astronomical spectroscopy have been added. Spectra of Atoms and Molecules demystifies spectroscopy by showing readers the intermediate steps in a derivation, as well as the final result.
New Orleans, the perfect place for Hollywood to come and make movies, after all it has distictive architecture, world famous restaurants and a quirky people. And on those tree shaded streets, an atmosphere which screams murder.
An essential reference book for sixties music lovers, this encyclopedic overview includes detailed chart statistics and biographical information for eighty songwriters and covers around two thousand songs, some of which are among the greatest ever written.
This book discusses the methods used in helio- and asteroseismology for the collection, analysis and interpretation of data. It is the first comprehensive discussion of helioseismic and asteroseismic methodology, collecting techniques from over 300 research papers spread out over decades, with a critical discussion and inter-comparison. It enables the reader to follow the path of inference from the collection of the data at the telescope through to the understanding gained in terms of the modeling of solar and stellar physics and stellar evolution.By focusing on how results are obtained, rather than on the results themselves, this book provides the essential background needed to understand this field, which is rapidly advancing due to the availability of modern observing facilities both on the ground and in space. The material is accessible for advanced undergraduates and post-graduates, and provides an essential resource for researchers in the field./a
This book presents a phenomenological approach to the field of solid state magnetism. It surveys the various theories and discusses their applicability in different types of materials. The text will be valuable as a text for graduate courses in magnetism and magnetic materials.
This package includes both Mathematical Statistics: Basic Ideas and Selected Topics, Volume I, Second Edition, as well as Mathematical Statistics: Basic Ideas and Selected Topics, Volume II. Volume I presents fundamental, classical statistical concepts at the doctorate level without using measure theory. It gives careful proofs of major results and explains how the theory sheds light on the properties of practical methods. Volume II covers a number of topics that are important in current measure theory and practice. It emphasizes nonparametric methods which can really only be implemented with modern computing power on large and complex data sets. In addition, the set includes a large number of problems with more difficult ones appearing with hints and partial solutions for the instructor.
This unique and encyclopedic reference work describes the evolution of the physics of modern shock wave and detonation from the earlier and classical percussion. The history of this complex process is first reviewed in a general survey. Subsequently, the subject is treated in more detail and the book is richly illustrated in the form of a picture gallery. This book is ideal for everyone professionally interested in shock wave phenomena.
This up-to-the-minute reference explores current trends, disease etiology and associations, novel assessment tools, and modern laboratory tests to promote coordinated treatment of comorbid substance abuse, psychiatric disease, and general medical conditions-recognizing the causal relationship between substance abuse and medical and psychiatric diso
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