Peter Trenkwalder's Books

Calcium Antagonists

A Critical Review

By: Helmut Lydtin,Peter Trenkwalder

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Calcium Antagonists

A Critical Review

By: Helmut Lydtin,Peter Trenkwalder

This volume critically and objectively analyses the literature up to 1989 and presents a guide to the practical use of all calcium antagonists which have been thoroughly investigated to date. It begins with a concise review of physiological principles as a basis for a discussion of the general and specific pharmacodynamics and pharmacokinetics of calcium antagonists. Special emphasis is given to their therapeutic use in practice, precise dosage schedules are provided, interactions with other medications described, and therapeutic alternatives considered.

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414

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642748872

ISBN 13

9783642748875

Nonconvulsive Status Epilepticus

By: Frank W. Drislane, MD,Peter W. Kaplan, MD

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Nonconvulsive Status Epilepticus

By: Frank W. Drislane, MD,Peter W. Kaplan, MD

The only comprehensive source of information on this frequently misdiagnosed problem, with information critical for physicians, ER and ICU doctors, and psychiatrists. An under-recognized condition that can potentially cause brain damage and even death, nonconvulsive status epilepticus (NCSE) is an important clinical problem, occurring in about 25% of status epilepsy cases. Despite this prevalence, Nonconvulsive Status Epilepticus is the first comprehensive clinical text to cover its diagnosis and management. The book progresses logically, beginning with chapters discussing the history and classification of NCSE, reflecting a contemporary understanding of developmental, syndromic, and clinical aspects. Following chapters discuss relevant epidemiology, electrophysiology, imaging and pathophysiology of NCSE, with supplementary sections devoted to psychiatric and behavioral aspects of NCSE and to the different diagnostic considerations of its frequently unusual behavioral presentations. Highlights include: An emphasis on diagnosis, management, and all pertinent clinical issues A heavily illustrated section on EEG interpretation in NCSE Contributions by the foremost international experts on NCSE Throughout, the book maintains a practical focus on recognizing the key signs and symptoms of this subtly presented and clinically challenging condition. This multidisciplinary volume will provide physicians, ER and ICU doctors, and psychiatrists with a comprehensive source of information and opinion on nonconvulsive status epilepticus.

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Page Count

317

Publisher

Demos Medical Publishing

Published Date

ISBN 10

1934559601

ISBN 13

9781934559604

Parkinsons's Disease

The Treatment Options

By: Peter Lewitt,Wolfgang H Oertel

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Parkinsons's Disease

The Treatment Options

By: Peter Lewitt,Wolfgang H Oertel

With the general population becoming increasingly aware of new developments for the diagnosis and treatment of certain neurological disorders throught increased media coverage in the popular press and on television and with celebrities being affected, the clinician must be aware of all the latest developments inthe diagnosis and treatment of disease. Parkinson's disease is no different. Peter LeWitt and Wolfgang Oertel have assembled an international team of contributors to write on their particular areas of expertise to produce a work which will help the practising clinician. This book captures all the latest information: the most important developments in the research of Parkinson's disease in recent years and the many different approaches to the treatment of the disease. These are exciting times for the study of Parkinson's disease, and this book condenses the wealth of available information into a practical text.

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Page Count

280

Publisher

CRC Press

Published Date

ISBN 10

1853173797

ISBN 13

9781853173790

Disjoined Partners

Austria and Germany since 1815

By: Peter Katzenstein

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Disjoined Partners

Austria and Germany since 1815

By: Peter Katzenstein

Is there a natural tendency toward the political integration of states that are united in culture but divided in politics? Disjoined Partners arrives at a largely negative response. In an application of political science techniques to a subject traditionally in the domain of history, Peter J. Katzenstein analyzes Austro-German relations since 1815 in six chronologically arranged case studies. Asking why these partners remain disjoined, Katzenstein finds the answer in the persistence of Austria’s political autonomy. In an appendix, the author illustrates how this type of analysis could be extended to include an examination of the unification of Germany and of Italy in the middle of the nineteenth century and of the fragmentation of Sweden-Norway and England-Ireland at the beginning of the twentieth. His study sheds new light on the reasons for the continued political autonomy of nation-states. Disjoined Partners derives from the author's dissertation, which was awarded the Charles Sumner Prize at Harvard and the American Political Science Association’s Helen Dwight Reid Award for the best dissertation of the year in the field of international relations, law, and politics. This title is part of UC Press's Voices Revived program, which commemorates University of California Press’s mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1976.

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281

Publisher

Univ of California Press

Published Date

ISBN 10

0520377443

ISBN 13

9780520377448

Sleep and Pain

By: Gilles Lavigne,Barry J. Sessle,Manon Choinière,Peter Soja

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Sleep and Pain

By: Gilles Lavigne,Barry J. Sessle,Manon Choinière,Peter Soja

Many in the research and clinical communities are becoming increasingly aware of the interactions between sleep disorders and chronic pain syndromes. There are a number of obstacles on the path to better patient care, and there is considerable room for improvement in the way knowledge is shared between professionals in the sleep and pain communities. This book serves as the first step toward enhancing communication between the sleep and pain communities with the intent of improving patient care.

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Page Count

570

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496332040

ISBN 13

9781496332042

Critical Pathways to Success in CNS Drug Development

By: Neal R. Cutler,John J. Sramek,Michael F. Murphy,Henry Riordan,Peter Biek,Angelico Carta

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Critical Pathways to Success in CNS Drug Development

By: Neal R. Cutler,John J. Sramek,Michael F. Murphy,Henry Riordan,Peter Biek,Angelico Carta

Covering the latest advances in CNS drug development, this bookwill guide all those involved in pre-clinical to early clinicaltrials. The authors describe how recent innovations can acceleratethe development of novel CNS compounds, improve early detection ofefficacy and toxicity signals, and increase the safety oflater-stage clinical trials. The current crisis in the drug development industry iscritically reviewed, as well as the steps needed to correct theproblems, including new government-backed regulations andindustry-based innovations designed to accelerate CNS drugdevelopment in the future. Animal-based models of major CNS disorders are described indetail, and the ability of the latest in vitro and computer-basedmodels to simulate CNS disease states and predict drug efficacy andside-effects are examined. Particular attention is given tothe growing use of biomarkers and how they can be used effectivelyin early human trials as signals of potential drug efficacy, aswell as the increasingly important role of imaging studies to guidedose selection. Cognitive assessments that can be useful indicatorsof effect in patient populations are also discussed. Written by a team of clinical scientists involved in CNS drugtrials for over 20 years, and based on a wealth of drug developmentand clinical trial experience, Critical Pathways to Success inCNS Drug Developmentis full of practical advice forsuccessfully designing and executing CNS drug trials, avoidingpotential pitfalls, and complying with government regulations

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Page Count

272

Publisher

John Wiley & Sons

Published Date

ISBN 10

1444318586

ISBN 13

9781444318586

HIV/AIDS and the Nervous System

By: Peter Portegies

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HIV/AIDS and the Nervous System

By: Peter Portegies

This volume provides a comprehensive understanding of HIV/AIDS and neuro-AIDS, including a history of the disease, and an explanation of many of the conditions that can arise in afflicted patients, including opportunistic infections, central nervous system tumors, spinal cord disorders, myopathies and progressive encephalopathy, amongst others. Clinicians will gain a greater understanding of the complex mechanisms of the disease. Beginning with a basic introduction to HIV infections and Neuro-AIDS, practitioners will find useful data on advances in molecular biology, neuroepidemiology, neuroimaging, neuropathology, neuropharmacology, as well as information on the development of therapeutic strategies appropriate for the disorder, including groundbreaking retroviral therapies. In addition, the socioeconomic and political constraints that hinder treatment and disease management in developing parts of the world are presented. * A comprehensive understanding of HIV/AIDS and neuro-AIDS, and the progression of the scientific community's understanding of the disease * Detailed information on fields such as neuroepidemiology, neuropathology, neuropharmacology, and neuroimaging and their contributions to HIV/AIDS research * Subject specific chapters on conditions associated with HIV/AIDS, including opportunistic infections, central nervous system tumors, and myopathies, amongst others

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Page Count

386

Publisher

Newnes

Published Date

ISBN 10

0444520104

ISBN 13

9780444520104

Clinical Neurology E-Book

A Primer

By: Peter Gates

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Clinical Neurology E-Book

A Primer

By: Peter Gates

This is a clinical neurology book for the student, non neurologist, and those that teach them. The book covers neuroanatomy, history taking and examination and then proceeds to discuss the clinical features of common problems as well as some of the more common rare, neurological disorders, in a way that will demystify a part of medicine that students find complex and difficult to understand. The book is accompanied by a DVD explaining concepts, demonstrating techniques of performing the neurological examination and demonstration of abnormal neurological signs. The first chapter is devoted to neuroanatomy from a clinical viewpoint. The concept of localising problems by likening the nervous system to a map grid with vertical meridians of longitude (the ascending sensory pathways and the descending motor pathway)and horizontal parallels of latitude (cortical signs, brainstem cranial nerves, nerve roots and peripheral nerves) of the nervous system is developed. Subsequent chapters take the reader through the neurological examination and the common neurological presentations from a symptom oriented approach. Chapter 4 contains a very simple method of understanding the brainstem, the "rule of 4". Chapter 6 discusses the approach after the history and examination are completed. The final chapter is an overview of how to approach information gathering and keeping up-to-date using the complex information streams available. - widely illustrated with case studies and illustrations - key points - clinical questions - clinical orientation with comprehensive references

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Page Count

425

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0729579352

ISBN 13

9780729579353

The Teaching Files

Brain and Spine

By: Girish Fatterpekar,Thomas P. Naidich,Peter M. Som

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The Teaching Files

Brain and Spine

By: Girish Fatterpekar,Thomas P. Naidich,Peter M. Som

Practical and clinically focused, Brain and Spine Imaging - a title in the Teaching Files Series - provides you with over 300 interesting and well-presented cases to help you better diagnose any disease of the brain and spine. Expert in the field, Dr. Girish Fatterpekar, MD uses a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for board exams. And, with Expert Consult functionality, you'll have convenient access to the full text online, all of the book's illustrations, additional cases and images, and links to PubMed at expertconsult.com. Get expert, practical guidance from over 300 cases, and brief but thorough descriptions of findings that help you make review easier than ever before. Conveniently reference the full text anytime, anywhere online at expertconsult.com, including all of the book's illustrations and links to Medline. Test your knowledge by turning image labels on and off. Stay current with the most up-to-date radiologic modalities and technologies. Provides brief but thorough descriptions of findings putting the information you need at your fingertips. Expand your knowledge with references to the most important sources on specific topics of interest. Find key information quickly and easily thanks to consistently formatted chapters that include Demographics/Clinical History; Findings; Discussion; Characteristic/Clinical Features; Radiologic Findings; Primary Differential Diagnosis; and Suggested Readings. See how to resolve challenging diagnostic questions by reviewing discussions of similar cases. Hone your skills, brush up on difficult diagnoses, and prepare for board exams with this essential case-based reference.

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Page Count

825

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1416056203

ISBN 13

9781416056201

The Teaching Files: Brain and Spine Imaging E-Book

By: Girish M. Fatterpekar,Thomas P. Naidich,Peter M. Som

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The Teaching Files: Brain and Spine Imaging E-Book

By: Girish M. Fatterpekar,Thomas P. Naidich,Peter M. Som

Practical and clinically focused, Brain and Spine Imaging - a title in the Teaching Files Series - provides you with over 300 interesting and well-presented cases to help you better diagnose any disease of the brain and spine. Expert in the field, Dr. Girish Fatterpekar, MD uses a logical organization throughout, making referencing difficult diagnoses easier than ever before. Detailed discussions of today's modalities and technologies keep you up to date, and challenging diagnostic questions probe your knowledge of the material. This unique, case-based resource offers you an ideal way to sharpen your diagnostic skills and study for board exams. Get expert, practical guidance from over 300 cases, and brief but thorough descriptions of findings that help you make review easier than ever before. Stay current with the most up-to-date radiologic modalities and technologies. Provides brief but thorough descriptions of findings putting the information you need at your fingertips. Expand your knowledge with references to the most important sources on specific topics of interest. Find key information quickly and easily thanks to consistently formatted chapters that include Demographics/Clinical History; Findings; Discussion; Characteristic/Clinical Features; Radiologic Findings; Primary Differential Diagnosis; and Suggested Readings. See how to resolve challenging diagnostic questions by reviewing discussions of similar cases.

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Page Count

824

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1455733636

ISBN 13

9781455733637

Endothelium and Cardiovascular Diseases

Vascular Biology and Clinical Syndromes

By: Protasio L. Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas

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Endothelium and Cardiovascular Diseases

Vascular Biology and Clinical Syndromes

By: Protasio L. Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. - Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information - Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress - Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

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Page Count

760

Publisher

Academic Press

Published Date

ISBN 10

0128125519

ISBN 13

9780128125519

Outlive

The Science and Art of Longevity

By: Peter Attia, MD

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Outlive

The Science and Art of Longevity

By: Peter Attia, MD

#1 NEW YORK TIMES BESTSELLER • OVER ONE MILLION COPIES SOLD • A groundbreaking manifesto on living better and longer that challenges the conventional medical thinking on aging and reveals a new approach to preventing chronic disease and extending long-term health, from a visionary physician and leading longevity expert “One of the most important books you’ll ever read.”—Steven D. Levitt, New York Times bestselling author of Freakonomics AN ECONOMIST AND BLOOMBERG BEST BOOK OF THE YEAR Wouldn’t you like to live longer? And better? In this operating manual for longevity, Dr. Peter Attia draws on the latest science to deliver innovative nutritional interventions, techniques for optimizing exercise and sleep, and tools for addressing emotional and mental health. For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimer’s disease, and type 2 diabetes. Too often, it intervenes with treatments too late to help, prolonging lifespan at the expense of healthspan, or quality of life. Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. This is not “biohacking,” it’s science: a well-founded strategic and tactical approach to extending lifespan while also improving our physical, cognitive, and emotional health. Dr. Attia’s aim is less to tell you what to do and more to help you learn how to think about long-term health, in order to create the best plan for you as an individual. In Outlive, readers will discover: • Why the cholesterol test at your annual physical doesn’t tell you enough about your actual risk of dying from a heart attack. • That you may already suffer from an extremely common yet underdiagnosed liver condition that could be a precursor to the chronic diseases of aging. • Why exercise is the most potent pro-longevity “drug”—and how to begin training for the “Centenarian Decathlon.” • Why you should forget about diets, and focus instead on nutritional biochemistry, using technology and data to personalize your eating pattern. • Why striving for physical health and longevity, but ignoring emotional health, could be the ultimate curse of all. Aging and longevity are far more malleable than we think; our fate is not set in stone. With the right roadmap, you can plot a different path for your life, one that lets you outlive your genes to make each decade better than the one before.

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425

Publisher

Harmony

Published Date

ISBN 10

0593236602

ISBN 13

9780593236604

Imitators of Epilepsy

By: Robert S Fisher, MD,Peter W. Kaplan, MD

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Imitators of Epilepsy

By: Robert S Fisher, MD,Peter W. Kaplan, MD

Many patients referred for an epilepsy evaluation actually suffer from one of many conditions that can imitate it. Imitators of epilepsy are a diverse group that involve consideration of many areas of internal medicine, neurology, and psychiatry. The most important imitators of epileptic seizures are dizziness, vertigo, syncope, complicated migraine; and somewhat less frequently sleep disorders, transient cerebral ischemia, paroxysmal movement disorders, endocrine or metabolic dysfunction, delirium, psychiatric conditions or transient global amnesia. Clearly under-recognized are hyperventilation episodes, panic attacks, and other psychogenic and psychiatric paroxysmal disorders that may simulate epileptic seizures. This volume provides a comprehensive review of the differential diagnosis of seizures: how do the imitators of epilepsy present clinically, what are their particular distinguishing historical features, and what tests are helpful with diagnosis? Expanding beyond the first edition, this second edition is divided into four sections. The first deals with an introduction and approach diagnosing spells, the electroencephalography of epilepsy and its imitators, and specialized tests of diagnosis such as measurement of serum prolactin. There are chapters on epileptic seizures that do not look like typical epileptic seizures, and conversely, apparent epileptic seizures that are not. A second section approaches imitators of epileptic seizures along age-based lines; i.e., what sorts of spells are likely to beset infants, children, or the elderly? A third section addresses individual imitators of epilepsy, ranging from the common to the rare, from dizziness and faintness to startle disease, arranged according to whether they might simulate partial, generalized, or both types of epileptic seizures. The volume finishes off with hyperventilation syndrome, psychogenic seizures (with or without epilepsy), and panic disorders. Most chapters review the basic definitions and physiology of the respective imitator, followed by the clinical characteristics. Emphasis is given to those features that may differentiate it from an epileptic event, but also mark it for what it is, and give possible criteria for an alternate diagnosis. Case vignettes are used to illustrate particular aspects, along with tables that compare and contrast phenotypically similar conditions. Based on their extensive clinical experience, the authors provide a personal perspective on diagnosis and treatment.

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Page Count

314

Publisher

Demos Medical Publishing

Published Date

ISBN 10

1934559199

ISBN 13

9781934559192

Calcium Antagonists

A Critical Review

By: Helmut Lydtin,Peter Trenkwalder

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Calcium Antagonists

A Critical Review

By: Helmut Lydtin,Peter Trenkwalder

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Page Count

414

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642748872

ISBN 13

9783642748875

Book's by Peter Trenkwalder

Calcium Antagonists

Calcium Antagonists

Nonconvulsive Status Epilepticus

Nonconvulsive Status Epilepticus

Parkinsons's Disease

Parkinsons's Disease

Disjoined Partners

Disjoined Partners

Sleep and Pain

Sleep and Pain

Critical Pathways to Success in CNS Drug Development

Critical Pathways to Success in CNS Drug Development

HIV/AIDS and the Nervous System

HIV/AIDS and the Nervous System

Clinical Neurology E-Book

Clinical Neurology E-Book

The Teaching Files

The Teaching Files

The Teaching Files: Brain and Spine Imaging E-Book

The Teaching Files: Brain and Spine Imaging E-Book

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases

Outlive

Outlive

Imitators of Epilepsy

Imitators of Epilepsy

Calcium Antagonists

Calcium Antagonists

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