This atlas focuses on selected aspects of cochlear anatomy as illustrated by material prepared by the microdissection technique, a three-dimensional perspective not possible with standard histological approaches. Although much of the material in this text was processed by the microdissection method, photomicrographs from conventionally cross sectioned inner ear tissues and scanning electron microscopy, are also presented. Taken together, these technical approaches provide different, complementary views of inner ear anatomy, and offer a more informative understanding than is possible with any of the methods used alone. While micrographs obtained from microdissected material appear sporadically in journal articles, there is no comprehensive collection of such images currently available. The illustrations assembled in this atlas are complementary to the more traditional histologic images and drawings available in standard texts, and aide in understanding the intricate anatomy of the cochlea. Cochlear Anatomy via Microdissection with Clinical Implications will be a useful resource for otolaryngologists, anatomists, audiologists, and neuroscientists. Those engaged in cochlear implantation, physicians and researchers in the growing fields of implantable hearing aids and drug delivery to the inner ear, and members of industry involved in designing, manufacturing, and marketing implantable hearing aids will also find this atlas of great value.
Any literate person should be familiar with the central ideas of modern science. In his sparkling new book, Peter Atkins introduces his choice of the ten great ideas of science. With wit, charm, patience, and astonishing insights, he leads the reader through the emergence of the concepts, and then presents them in a strikingly effective manner. At the same time, he works into his engaging narrative an illustration of the scientific method and shows how simple ideas can have enormous consequences. His choice of the ten great ideas are: * Evolution occurs by natural selection, in which the early attempts at explaining the origin of species is followed by an account of the modern approach and some of its unsolved problems. * Inheritance is encoded in DNA, in which the story of the emergence of an understanding of inheritance is followed through to the mapping of the human genome. * Energy is conserved, in which we see how the central concept of energy gradually dawned on scientists as they mastered the motion of particles and the concept of heat. * All change is the consequence of the purposeless collapse of energy and matter into disorder, in which the extraordinarily simple concept of entropy is used to account for events in the world. * Matter is atomic, in which we see how the concept of atoms emerged and how the different personalities of the elements arise from the structures of their atoms. * Symmetry limits, guides, and drives, in which we see how concepts related to beauty can be extended to understand the nature of fundamental particles and the forces that act between them. * Waves behave like particles and particles behave like waves, in which we see how old familiar ideas gave way to the extraordinary insights of quantum theory and transformed our perception of matter. * The universe is expanding, in which we see how a combination of astronomy and a knowledge of elementary particles accounts for the origin of the universe and its long term future. * Spacetime is curved by matter, in which we see the emergence of the theories of special and general relativity and come to understand the nature of space and time. * If arithmetic is consistent, then it is incomplete, in which we learn the origin of numbers and arithmetic, see how the philosophy of mathematics lets us understand the nature of this most cerebral of subjects, and are brought to the limits of its power. C. P. Snow once said 'not knowing the second law of thermodynamics is like never having read a work by Shakespeare'. This is an extraordinary, exciting book that not only will make you literate in science but give you deep enjoyment on the way.
From the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options. - Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams. - Make the most accurate Tropical Disease diagnoses through a completely redesigned and modernized format, which includes full-color images throughout plus a wealth of additional illustrations online at Expert Consult. - Apply the latest treatment strategies for HIV/AIDS, tropical neurology, malaria, and much more. - Put the latest international expertise to work for you and your patients with new chapters covering Global Health; Global Health Governance and Tropical Diseases; Non-communicable Diseases; Obesity in the Tropics; and Emergency and Intensive Care Medicine in Resource-poor Settings. - See which diseases are most prevalent in specific areas of the tropics through a new index of diseases by country, as well as online-only maps that provide additional detail. - Better understand the variations in treatment approaches across the globe.
The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essential for those involved in drug safety evaluation, including pathologists, toxicologists and pharmacologists working in corporate, government, academic and research settings. - This edition is in full color and features nearly 200 high-quality images - Provides extended commentary on the relevance of pathological findings and features a fully updated bibliography containing sources for further reading - Includes new content coverage on the commonly used transgenic animal models that are used in safety assessment, specific tumor types induced by drugs in rodents, and new drug-induced pathologies and lesions
From the early passions of the 'Latin Lover of the silver screen', to the adventures of modem-day heroes such as Antonio Banderas, this is an illuminating voyage into the careers and contributions of some of film history's most legendary performers. The book is a fascinating Who's Who of superstars, including Jennifer Lopez, Andy Garcia, Salma Hayek, Cameron Diaz, Freddie Prinze Jr, Jimmy Smits, John Leguizamo, Penelope Cruz and many more. The book gives readers not an entertaining but also an important record of Hispanic contributions to the greatest art form of the twentieth century. Some 400 films and television shows from the past years are listed with credits, synopses, production information relating to Hispanic stars and their contributions, as well as critical commentary. Contains an alphabetical listing of Hispanic/Latino actors, actresses, directors, producers and other behind-the-scenes people, together with their biographies. The book is beautifully illustrated with black-and-white photographs' selected from co-author Luis Reyes' personal collection.
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