A guide to wave-field computational methods based on contrast source type of integral equations Forward and Inverse Scattering Algorithms Based on Contrast Source Integral Equations presents a text that examines wave-field computational methods based on contrast source type of integral equations and the computational implementation in wave-field based imaging methods. Written by a noted expert on the topic, the book provides a guide to efficient methods for calculating wave fields in a known inhomogeneous medium. The author provides a link between the fundamental scattering theory and its discrete counterpart and discusses the forward scattering problem based on the contrast-source integral equations. The book fully describes the calculation of wave fields inside and outside a scattering object with general shape and material property and reviews the inverse scattering problem, in which material properties are resolved from wave-field measurements outside the scattering object. The theoretical approach is the inverse of the forward scattering problem that determines how radiation is scattered, based on the scattering object. This important book: Provides a guide to the effects of scalar waves, acoustic waves and electromagnetic waves Describes computer modeling in 1D, 2D and 3D models Includes an online site for computer codes with adjustable configurations Written for students, researchers, and professionals, Forward and Inverse Scattering Algorithms Based on Contrast Source Integral Equations offers a guide to wave-field computational methods based on contrast source type of integral equations and the computational implementation in wave-field based imaging methods.
A comprehensive guide to North Africa's most popular destination, this text features coverage of the resorts - Hammamet, Sousse, Port el Kantaoui - and their beaches, with details of excursions, including trips to the Star Wars film set; recommendations of places to eat and stay for all budgets; accounts of all the sights; advice on getting around the country; and background on Tunisian history, culture and society, wildlife, and the country's passion for football.
The first full-length study of cycling activism through the lens of social movement theory, this book demonstrates that, despite tremendous differences, bike activism can be understood as a continuous and connected activity spanning a century and a half and across continents. With examples from street protest to institutional lobbying, it emphasises cycling’s current central importance to zero carbon transport futures, while showing that cycling activism is also not always about the bike or the cyclist, as successive generations of activists have used cycling to articulate different visions of freedom and autonomy. Moving from a consideration of social movement theory as a means to understand cycling activism, the author presents a series of case studies of collective action, organisations, networks and campaigns in order to illustrate and elaborate a theoretical model through which diverse campaigns and approaches to change can be understood. As such, Cycling Activism will appeal to those with interests in mobilisation for social change, mobility and transport studies, and social movement theory, as well as cycling studies.
Software systems play an increasingly important role in modern societies. Smart cards for personal identi?cation, e-banking, software-controlled me- cal tools, airbags in cars, and autopilots for aircraft control are only some examples that illustrate how everyday life depends on the good behavior of software. Consequently, techniques and methods for the development of hi- quality, dependable software systems are a central research topic in computer science. A fundamental approach to this area is to use formal speci?cation and veri?cation. Speci?cation languages allow one to describe the crucial p- perties of software systems in an abstract, mathematically precise, and implementation-independent way. By formal veri?cation, one can then prove that an implementation really has the desired, speci?ed properties. Although this formal methods approach has been a research topic for more than 30 years, its practical success is still restricted to domains in which devel- ment costs are of minor importance. Two aspects are crucial to widen the application area of formal methods: – Formal speci?cation techniques have to be smoothly integrated into the software and program development process. – The techniques have to be applicable to reusable software components. This way, the quality gain can be exploited for more than one system, thereby justifying the higher development costs. Starting from these considerations, Peter Muller ̈ has developed new te- niques for the formal speci?cation and veri?cation of object-oriented so- ware. The speci?cation techniques are declarative and implementati- independent. They can be used for object-oriented design and programming.
The new Companion to Peripheral Neuropathy: Illustrated Case Studies by Dr. Peter J. Dyck, et al, which supplements Dyck and Thomas’ authoritative and comprehensive Peripheral Neuropathy, features illustrated case studies that explore the evaluation and management of the most common peripheral nerve disorders. Leading authorities in the field contribute clues to the diagnosis, clinical features, imaging studies, histopathology and more for each case. You’ll gain new insights into the causes of peripheral nerve disorders to help you diagnose and treat every condition. Offers new insights in clinical and electrophysiologic characterization, imaging, histopathology, and molecular genetics Shows you how abstract diagnosis and management principles apply in real situations Presents more illustrations than any competing reference so you can see disorders as they present in practice Offers expert clues to help you diagnose and manage patients quickly and effectively Provides references to the most significant literature in the field so you can stay at the forefront of this science
Increasing numbers of general practitioners are discovering the benefits of working with Positive Health. It helps to talk with patients in a different way, with a focus on possibilities rather than on the impossibilities related to a particular health problem. This is good for the patient. And for the general practitioner. But how do we apply Positive Health? This handbook provides useful tools! The book is full of tips, tells the story of how the concept was first developed and gives practical examples. It explains the underlying scientific basis of Positive Health — with a clear emphasis on what is meaningful to patients. And, above all, this book invites you to start working with Positive Health on various levels — in your consulting room, your practice and in the local community. Because cooperation and combined effort are key. You will experience how Positive Health seamlessly fits the core values and challenges of all aspects of primary care. The handbook is intended for all primary care professionals as well as those who are still in training. It describes the Dutch health care system and the experiences related to inspiration, implementation and the anchoring of the Positive Health concept into this system. The publication is indispensable for anyone who wants to provide meaningful primary care using the Positive Health concept. ‘When I heard about Positive Health and the spider web, I felt that it gave us a much wanted tool to empower our patients and the community.’ Elínborg Bárðardóttir, general practitioner & programme director primary care training, Primary Healthcare in Iceland
The great expansion of economic activity since the end of World War II has caused an unprecedented rise in living standards, but it has also caused rapid changes in earth systems. Nearly all types of natural capital—the world’s stock of resources and services provided by nature—are in decline. Clean air, abundant and clean water, fertile soils, productive fisheries, dense forests, and healthy oceans are critical for healthy lives and healthy economies. Mounting pressures, however, suggest that the trend of declining natural capital may cast a long shadow into the future. Nature’s Frontiers: Achieving Sustainability, Efficiency, and Prosperity with Natural Capital presents a novel approach to address these foundational challenges of sustainability. A methodology combining innovative science, new data sources, and cutting-edge biophysical and economic models builds sustainable resource efficiency frontiers to assess how countries can sustainably use their natural capital more efficiently. The analysis provides recommendations on how countries can better use their natural capital to achieve their economic and environ mental goals. The report indicates that significant efficiency gaps exist in nearly every country. Closing these gaps can address many of the world’s pressing economic and environmental problems—economic productivity, health, food and water security, and climate change. Although the approach outlined in this report will entail demanding policy reforms, the costs of inaction will be far higher.
The four-volume set LNCS 2657, LNCS 2658, LNCS 2659, and LNCS 2660 constitutes the refereed proceedings of the Third International Conference on Computational Science, ICCS 2003, held concurrently in Melbourne, Australia and in St. Petersburg, Russia in June 2003. The four volumes present more than 460 reviewed contributed and invited papers and span the whole range of computational science, from foundational issues in computer science and algorithmic mathematics to advanced applications in virtually all application fields making use of computational techniques. These proceedings give a unique account of recent results in the field.
This comprehensive and practical reference is the perfect resource for the medical specialist treating persons with spinal cord injuries. The book provides detail about all aspects of spinal cord injury and disease. The initial seven chapters present the history, anatomy, imaging, epidemiology, and general acute management of spinal cord injury. The next eleven chapters deal with medical aspects of spinal cord damage, such as pulmonary management and the neurogenic bladder. Chapters on rehabilitation are followed by nine chapters dealing with diseases that cause non-traumatic spinal cord injury. A comprehensive imaging chapter is included with 30 figures which provide the reader with an excellent resource to understand the complex issues of imaging the spine and spinal cord.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. - Summarizes the key morphological and cellular events - Emphasizes up-to-date research relating to molecular control mechanisms - Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease - Distils common themes and differences for comparative studies - Highlights key remaining questions and sets the agenda for future research
This open access book is a practical introduction to multilevel modelling or multilevel analysis (MLA) – a statistical technique being increasingly used in public health and health services research. The authors begin with a compelling argument for the importance of researchers in these fields having an understanding of MLA to be able to judge not only the growing body of research that uses it, but also to recognise the limitations of research that did not use it. The volume also guides the analysis of real-life data sets by introducing and discussing the use of the multilevel modelling software MLwiN, the statistical package that is used with the example data sets. Importantly, the book also makes the training material accessible for download – not only the datasets analysed within the book, but also a freeware version of MLwiN to allow readers to work with these datasets. The book’s practical review of MLA comprises: Theoretical, conceptual, and methodological background Statistical background The modelling process and presentation of research Tutorials with example datasets Multilevel Modelling for Public Health and Health Services Research: Health in Context is a practical and timely resource for public health and health services researchers, statisticians interested in the relationships between contexts and behaviour, graduate students across these disciplines, and anyone interested in utilising multilevel modelling or multilevel analysis. “Leyland and Groenewegen’s wealth of teaching experience makes this book and its accompanying tutorials especially useful for a practical introduction to multilevel analysis.” ̶ Juan Merlo, Professor of Social Epidemiology, Lund University “Comprehensive and insightful. A must for anyone interested in the applications of multilevel modelling to population health”. ̶ S. (Subu) V. Subramanian, Professor of Population Health and Geography, Harvard University
Now ubiquitous in modern life, spatial data present great opportunities to transform many of the processes on which we base our everyday lives. However, not only do these data depend on the scale of measurement, but also handling these data (e.g., to make suitable maps) requires that we account for the scale of measurement explicitly. Scale in Spatial Information and Analysis describes the scales of measurement and scales of spatial variation that exist in the measured data. It provides you with a series of tools for handling spatial data while accounting for scale. The authors detail a systematic strategy for handling scale issues from geographic reality, through measurements, to resultant spatial data and their analyses. They also explore a process-pattern paradigm in approaching scale issues. This is well reflected, for example, in chapters dealing with terrain analysis, in which scale in terrain derivatives is described in relation to the processing involved in the derivation of specific terrain variables from elevation data, and area classes, which are viewed as driven by class-forming covariates. Lastly, this book provides coverage of some of the issues related to scale that are relatively under-represented in the literature, such as the effects of scale on information content in remotely sensed images, and the interaction between scale and uncertainty that is increasingly important for spatial information and analysis. By taking a rigorous, scientific approach to scale and its various meanings in relation to the geographic world, the book alleviates some of the frustration caused by dealing with issues of scale. While past research has led to an increasing number of journal articles and a few books dedicated to scale modeling and change of scale, this book helps you to develop coherent strategies for scale modeling, highlighting applicability for a variety of fields, from geomatic engineering and geoinformatics to environmental modeling.
Prevention and Management of Cardiovascular and Metabolic Disease Provides accurate and well-documented information on the impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases and healthy aging. This authoritative textbook examines the independent and combined impact of diet and physical activity in the prevention and management of cardiovascular and metabolic diseases, with special emphasis on the elderly populations. In this book the authors: Provide the latest data on the association between a suboptimal diet and physical inactivity and chronic disease. Examine the role of epigenetics on longevity. Discuss the fundamentals of healthy aging. Highlight the role of well-known dietary patterns such as the Mediterranean diet and the Nordic diet in favorable health outcomes, including cardiovascular, metabolic health, and healthy aging. Discuss the health outcomes of physical activity and healthy aging. Present the most recent evidence-based data on the independent and synergistic impact of diet and exercise on disease prevention and management including, heart disease, diabetes mellitus, hypertension, dyslipidemia, kidney failure, cancer and other conditions. Prevention and Management of Cardiovascular and Metabolic Disease: Diet, Physical Activity and Healthy Aging is an excellent textbook for upper-level undergraduate and graduate students in medical and health-related disciplines and for health professionals, including dietitians and nutritionists, exercise physiologists, athletic trainers, nurses, physicians, geriatricians, and other health professionals with a special focus in older adults. This book is also a highly useful reference for health professionals interested in introducing diet and physical activity as an intervention for healthy aging as well as the prevention and management of cardiovascular and other metabolic diseases that are prevalent in aging populations.
This book constitutes the refereed proceedings of the 12th International Conference on Algorithms and Computation, ISAAC 2001, held in Christchurch, New Zealand in December 2001. The 62 revised full papers presented together with three invited papers were carefully reviewed and selected from a total of 124 submissions. The papers are organized in topical sections on combinatorial generation and optimization, parallel and distributed algorithms, graph drawing and algorithms, computational geometry, computational complexity and cryptology, automata and formal languages, computational biology and string matching, and algorithms and data structures.
Algorithms are at the heart of every nontrivial computer application, and algorithmics is a modern and active area of computer science. Every computer scientist and every professional programmer should know about the basic algorithmic toolbox: structures that allow efficient organization and retrieval of data, frequently used algorithms, and basic techniques for modeling, understanding and solving algorithmic problems. This book is a concise introduction addressed to students and professionals familiar with programming and basic mathematical language. Individual chapters cover arrays and linked lists, hash tables and associative arrays, sorting and selection, priority queues, sorted sequences, graph representation, graph traversal, shortest paths, minimum spanning trees, and optimization. The algorithms are presented in a modern way, with explicitly formulated invariants, and comment on recent trends such as algorithm engineering, memory hierarchies, algorithm libraries and certifying algorithms. The authors use pictures, words and high-level pseudocode to explain the algorithms, and then they present more detail on efficient implementations using real programming languages like C++ and Java. The authors have extensive experience teaching these subjects to undergraduates and graduates, and they offer a clear presentation, with examples, pictures, informal explanations, exercises, and some linkage to the real world. Most chapters have the same basic structure: a motivation for the problem, comments on the most important applications, and then simple solutions presented as informally as possible and as formally as necessary. For the more advanced issues, this approach leads to a more mathematical treatment, including some theorems and proofs. Finally, each chapter concludes with a section on further findings, providing views on the state of research, generalizations and advanced solutions.
The leading reference on this topic has just gotten better. Building on the success of the previous two editions, all the chapters have been updated to reflect the latest developments in the field, and new chapters have been added on picolinic acids, oxathiapiprolin, flupyradifurone, and other topics. This third edition presents the most important active ingredients of modern agrochemicals, with one volume each for herbicides, fungicides, and insecticides. The international team of first-class authors from such renowned crop science companies as Bayer, Syngenta, Dow AgroSciences, DuPont (now Corteva Agriscience), and BASF, address all crucial aspects from the general chemistry and the mode of action to industrial-scale synthesis, as well as from the development of products and formulations to their application in the field. A comprehensive and invaluable source of timely information for all of those working in modern biology, including genetics, biochemistry and chemistry, and for those in modern crop protection science, whether governmental authorities, researchers in agrochemical companies, scientists at universities, conservationists, or managers in organizations and companies involved in improvements to agricultural production.
A great deal of progress has been made recently in the field of asymptotic formulas that arise in the theory of Dirac and Laplace type operators. Asymptotic Formulae in Spectral Geometry collects these results and computations into one book. Written by a leading pioneer in the field, it focuses on the functorial and special cases methods of computing asymptotic heat trace and heat content coefficients in the heat equation. It incorporates the work of many authors into the presentation, and includes a complete bibliography that serves as a roadmap to the literature on the subject. Geometers, mathematical physicists, and analysts alike will undoubtedly find this book to be the definitive book on the subject
Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process. This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority, cluster and stepped wedge trials. Other new chapters describe data and safety monitoring, biomarker studies, and feasibility studies. Updated and expanded sections discuss situations where multiple organs, different body locations or competing risks are involved, subgroup analysis, and multiple outcomes. Written by an author team with extensive experience in conducting clinical trials, this book: Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced Features several new chapters, updated case studies and examples, and references to changes in regulations Explains basic randomised trials, including the parallel two-group controlled trial with a single outcome measure Covers paired trial designs and trials with more than two interventions Includes a chapter on miscellaneous topics such as adaptive designs, large simple trials, Bayesian methods for very small trials, alpha-spending functions and the predictive probability test Randomised Clinical Trials is essential reading for clinicians, nurses, data managers, and medical statisticians involved in clinical trials, and for health practitioners responsible for direct patient care in a clinical trial setting.
Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals both man-made and natural that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.
This issue of the Psychiatric Clinics, edited by Dr. Peter F. Buckley, examines advances and current management in the treatment of Schizophrenia. The topics covered in this issue include, but are not limited to: Duration of Untreated Psychosis (DUP) and Longitudinal Perspectives on DUP; Neuroinflammation and Schizophrenia; Emerging Treatments for Schizophrenia; Treatment-Resistant Schizophrenia; Comorbidities and Schizophrenia; Recovery from Schizophrenia; and the latest in schizophrenia research.
The #1 text in Sports Medicine! This cornerstone textbook has been updated with the latest research and developments. Brukner & Khan's world-leading title provides an authoritative foundation for clinicians and students. This complete practical guide to physiotherapy and musculoskeletal medicine covers all aspects of diagnosis and contemporary management of sports-related injuries. The fifth edition has been expanded to accommodate a much higher level of evidence-based content and reflects the huge amount of new research and significant changes in thinking since the previous edition was published. The contributing editors are an international compilation of globally recognised experts within their fields. This is essential reading for sports medicine physicians, physical therapists and physical therapy students. Topics in Volume Two Include: •Exercise and health •Exercise and disease •Environment •Harassment and abuse •Special groups •Maximising athletic performance •Nutrition for performance
Field Crop Arthropod Pests of Economic Importance presents detailed descriptions of the biology and ecology of important arthropod pest of selected global field crops. Standard management options for insect pest control on crops include biological, non-chemical, and chemical approaches. However, because agricultural crops face a wide range of insect pests throughout the year, it can prove difficult to find a simple solution to insect pest control in many, if not most, cropping systems. A whole-farm or integrated pest management approach combines cultural, natural, and chemical controls to maintain insect pest populations below levels that cause economic damage to the crop. This practice requires accurate species identification and thorough knowledge of the biology and ecology of the target organism. Integration and effective use of various control components is often enhanced when the target organism is correctly identified, and its biology and ecology are known. This book provides a key resource toward that identification and understanding. Students and professionals in agronomy, insect detection and survey, and economic entomology will find the book a valuable learning aid and resource tool. - Includes insect synonyms, common names, and geographic distribution - Provides information on natural enemies - Is thoroughly referenced for future research
This book provides an introduction to ocean sciences that is engaging, evocative and accessible to non-experts interested in marine geoscience, while sparking readers' interest in important unsolved mysteries in marine science. The scope of the book is quite broad, but focuses on the physical ocean and its geological evolution, including the author's experiences working as an oceanographer over the last thirty years. Across ten chapters, the book traces the origins of the ocean from its formation 4 billion years ago, reviews the discoveries of the theory of plate tectonics, the ice ages and the great ocean conveyor, and discusses seafloor features (canyons, seamounts, trenches, abyssal plains, etc.), how they formed and their current environmental issues. The book concludes with a prognosis for the future ocean we might expect with global climate change and other human impacts.
This cutting-edge, standard-setting text explores the spectral geometry of Riemannian submersions. Working for the most part with the form valued Laplacian in the class of smooth compact manifolds without boundary, the authors study the relationship-if any-between the spectrum of Dp on Y and Dp on Z, given that Dp is the p form valued Laplacian and pi: Z ® Y is a Riemannian submersion. After providing the necessary background, including basic differential geometry and a discussion of Laplace type operators, the authors address rigidity theorems. They establish conditions that ensure that the pull back of every eigenform on Y is an eigenform on Z so the eigenvalues do not change, then show that if a single eigensection is preserved, the eigenvalues do not change for the scalar or Bochner Laplacians. For the form valued Laplacian, they show that if an eigenform is preserved, then the corresponding eigenvalue can only increase. They generalize these results to the complex setting as well. However, the spinor setting is quite different. For a manifold with non-trivial boundary and imposed Neumann boundary conditions, the result is surprising-the eigenvalues can change. Although this is a relatively rare phenomenon, the authors give examples-a circle bundle or, more generally, a principal bundle with structure group G where the first cohomology group H1(G;R) is non trivial. They show similar results in the complex setting, show that eigenvalues can decrease in the spinor setting, and offer a list of unsolved problems in this area. Moving to some related topics involving questions of positive curvature, for the first time in mathematical literature the authors establish a link between the spectral geometry of Riemannian submersions and the Gromov-Lawson conjecture. Spectral Geometry, Riemannian Submersions, and the Gromov-Lawson Conjecture addresses a hot research area and promises to set a standard for the field. Researchers and applied mathematicians interested in mathematical physics and relativity will find this work both fascinating and important.
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