The completely revised and expanded edition of What They’ll Never Tell You About the Music Business is a must-have reference. You’ll learn: - How many musicians have seized do-it-yourself internet opportunities to create successful business models, - How the royalty pie is sliced—and who gets the pieces, - How the fundamentals of music publishing, producing, managing, touring, and the record industry apply more than ever, - Why this book is the indispensable guide to the worldwide music industry, - How corporate general counsels can educate their employees (and themselves) to understand the strictures of copyright law and to avoid trouble, - And much more.
This book illustrates numerous statistical practices that are commonly used by medical researchers, but which have severe flaws that may not be obvious. For each example, it provides one or more alternative statistical methods that avoid misleading or incorrect inferences being made. The technical level is kept to a minimum to make the book accessible to non-statisticians. At the same time, since many of the examples describe methods used routinely by medical statisticians with formal statistical training, the book appeals to a broad readership in the medical research community.
Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to determine this quickly and terminate the clinical evaluation process to avoid wasting resources. Bayesian Designs for Phase I–II Clinical Trials describes how phase I–II designs can serve as a bridge or protective barrier between preclinical studies and large confirmatory clinical trials. It illustrates many of the severe drawbacks with conventional methods used for early-phase clinical trials and presents numerous Bayesian designs for human clinical trials of new experimental treatment regimes. Written by research leaders from the University of Texas MD Anderson Cancer Center, this book shows how Bayesian designs for early-phase clinical trials can explore, refine, and optimize new experimental treatments. It emphasizes the importance of basing decisions on both efficacy and toxicity.
The completely revised and expanded edition of What They’ll Never Tell You About the Music Business is a must-have reference. You’ll learn: - How many musicians have seized do-it-yourself internet opportunities to create successful business models, - How the royalty pie is sliced—and who gets the pieces, - How the fundamentals of music publishing, producing, managing, touring, and the record industry apply more than ever, - Why this book is the indispensable guide to the worldwide music industry, - How corporate general counsels can educate their employees (and themselves) to understand the strictures of copyright law and to avoid trouble, - And much more.
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