A clear methodological and philosophical introduction to complexity theory as applied to urban and regional systems is given, together with a detailed series of modelling case studies compiled over the last couple of decades. Based on the new complex systems thinking, mathematical models are developed which attempt to simulate the evolution of towns, cities, and regions and the complicated co-evolutionary interaction there is both between and within them. The aim of these models is to help policy analysis and decision-making in urban and regional planning, energy policy, transport policy, and many other areas of service provision, infrastructure planning, and investment that are necessary for a successful society.
For three editions, Rosen’s Breast Pathology has been widely recognized as the “gold standard” reference. Now in its Fourth Edition, this classic text continues its legacy of being the leading reference work on the pathology of the breast. Precise pathological diagnosis of breast disease is the most critical factor in determining treatment and establishing prognosis. The Fourth Edition of Rosen’s Breast Pathology provides the most comprehensive, updated information on diseases of the breast. Intended primarily for pathologists, the book will be an indispensible reference for all surgeons, oncologists, radiologists, radiation oncologists, as well as other physicians and medical personnel who require a thorough knowledge of breast pathology to provide optimal care for their patients. Discussions of most disease entities include clinical and radiological presentation, epidemiology, gross pathology, microscopic pathology, treatment, and prognosis. Surgical and oncological aspects of the various diseases are addressed wherever appropriate. Numerous images, a large proportion of which are new, complement the encyclopedic descriptions of the surgical pathology and cytology of diseases of the breast.
This book provides a critical assessment and examination of the prose and poetry of Ireland's Samuel Ferguson. It presents a clear understanding of the shape and purpose of Ferguson's career as a writer, which extended over half a century. The scholarly sources from which Ferguson extracted many of his themes are carefully examined, as are the times during which Ferguson lived and wrote. This book will be of great interest to students and scholars of Irish literature, and the politics and history of nineteenth century Ireland. CONTENTS Introduction; Early Periodical Writings; Hibernian Nights' Entertainments R and Other Fiction; The 1840s: A New Beginning; Lays of the Western Gael and Other Poems I; Lays of the Western Gael and Other Poems II; Congal; Poems; Passing On; Notes; Samuel Ferguson: A Chronology; A Checklist of Samuel Ferguson's Published Writings; Bibliography; Index R. Irish Literary Studies Series No. 39.
The book describes what it means to say the world is complex and explores what that means for managers, policy makers and individuals. The first part of the book is about the theory and ideas of complexity. This is explained in a way that is thorough but not mathematical. It compares differing approaches, and also provides a historical perspective, showing how such thinking has been around since the beginning of civilisation. It emphasises the difference between a complexity worldview and the dominant mechanical worldview that underpins much of current management practice. It defines the complexity worldview as recognising the world is interconnected, shaped by history and the particularities of context. The comparison of the differing approaches to modelling complexity is unique in its depth and accessibility. The second part of the book uses this lens of complexity to explore issues in the fields of management, strategy, economics, and international development. It also explores how to facilitate others to recognise the implications of adopting a complex rather than a mechanical worldview and suggests methods of research to explore systemic, path-dependent emergent aspects of situations. The authors of this book span both science and management, academia and practice, thus the explanations of science are authoritative and yet the examples of changing how you live and work in the world are real and accessible. The aim of the book is to bring alive what complexity is all about and to illustrate the importance of loosening the grip of a modernist worldview with its hope for prediction, certainty and control.
For 125 years, physicians have relied on Manson's Tropical Diseases for a comprehensive clinical overview of this complex and fast-changing field. The fully revised 24th Edition, Dr. Jeremy Farrar, along with an internationally recognized editorial team, global contributors, and expert authors, delivers the latest coverage on parasitic and infectious diseases from around the world. From the difficult to diagnose to the difficult to treat, this highly readable, award-winning reference prepares you to effectively handle whatever your patients may have contracted. - Covers all of tropical medicine in a comprehensive manner, general medicine in the tropics, and non-clinical issues regarding public health and ethics. - Serves as an indispensable resource for physicians who treat patients with tropical diseases and/or will be travelling to the tropics, or who are teaching others in this area. - Contains a new section on 21st Century Drivers of Tropical Medicine, with chapters covering Poverty and Inequality, Public Health in Settings of Conflict and Political Instability, Climate Change, and Medical Product Quality and Public Health. - Includes all-new chapters on Surgery in the Topics, Yellow Fever, Systemic Mycoses, and COVID-19. - Covers key topics such as drug resistance; emerging and reemerging infections such as Zika, Ebola, and Chikungunya; novel diagnostics such as PCR-based methods; point-of care-tests such as ultrasound; public health in settings of conflict and political instability; and much more. - Differentiates approaches for resource-rich and resource-poor areas. - Includes reader-friendly features such as highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.
2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. - Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. - Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. - Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. - Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. - Access the entire text and illustrations online, fully searchable, at Expert Consult.
This book constitutes the refereed proceedings of the 13th International Conference on Field-Programmable Logic and Applications, FPL 2003, held in Lisbon, Portugal in September 2003. The 90 revised full papers and 56 revised poster papers presented were carefully reviewed and selected from 216 submissions. The papers are organized in topical sections on technologies and trends, communications applications, high level design tools, reconfigurable architecture, cryptographic applications, multi-context FPGAs, low-power issues, run-time reconfiguration, compilation tools, asynchronous techniques, bio-related applications, codesign, reconfigurable fabrics, image processing applications, SAT techniques, application-specific architectures, DSP applications, dynamic reconfiguration, SoC architectures, emulation, cache design, arithmetic, bio-inspired design, SoC design, cellular applications, fault analysis, and network applications.
Understanding the dynamics of reactive polymer processes allows scientists to create new, high-value, high-performance polymers. This book is an indispensable resource for researchers and practitioners working in this area. It includes coverage of thermoplastics, thermoset and reactive polymers, together with practical industrial processes and modern chemorheological models and tools.
The Action Plan for Australian Mammals 2012 is the first review to assess the conservation status of all Australian mammals. It complements The Action Plan for Australian Birds 2010 (Garnett et al. 2011, CSIRO Publishing), and although the number of Australian mammal taxa is marginally fewer than for birds, the proportion of endemic, extinct and threatened mammal taxa is far greater. These authoritative reviews represent an important foundation for understanding the current status, fate and future of the nature of Australia. This book considers all species and subspecies of Australian mammals, including those of external territories and territorial seas. For all the mammal taxa (about 300 species and subspecies) considered Extinct, Threatened, Near Threatened or Data Deficient, the size and trend of their population is presented along with information on geographic range and trend, and relevant biological and ecological data. The book also presents the current conservation status of each taxon under Australian legislation, what additional information is needed for managers, and the required management actions. Recovery plans, where they exist, are evaluated. The voluntary participation of more than 200 mammal experts has ensured that the conservation status and information are as accurate as possible, and allowed considerable unpublished data to be included. All accounts include maps based on the latest data from Australian state and territory agencies, from published scientific literature and other sources. The Action Plan concludes that 29 Australian mammal species have become extinct and 63 species are threatened and require urgent conservation action. However, it also shows that, where guided by sound knowledge, management capability and resourcing, and longer-term commitment, there have been some notable conservation success stories, and the conservation status of some species has greatly improved over the past few decades. The Action Plan for Australian Mammals 2012 makes a major contribution to the conservation of a wonderful legacy that is a significant part of Australia’s heritage. For such a legacy to endure, our society must be more aware of and empathetic with our distinctively Australian environment, and particularly its marvellous mammal fauna; relevant information must be readily accessible; environmental policy and law must be based on sound evidence; those with responsibility for environmental management must be aware of what priority actions they should take; the urgency for action (and consequences of inaction) must be clear; and the opportunity for hope and success must be recognised. It is in this spirit that this account is offered.
The authors of this book link productivity change, trade competitiveness, networks of interaction and cooperation and income growth in developing Asian countries with the complex evolutionary processes of economic development and international trade. They take an innovative approach to simulating the complex micro-dynamics of competitiveness in order to distinguish those trade-related microeconomic dynamics and institutional reforms vital to leading countries out of institutional and poverty traps.
Do we have introspective access to our own thoughts? Peter Carruthers challenges the consensus that we do: he argues that access to our own thoughts is always interpretive, grounded in perceptual awareness and sensory imagery. He proposes a bold new theory of self-knowledge, with radical implications for understanding of consciousness and agency.
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This book presents a novel way to enable people, regardless of their scale of influence, to take responsibility for global environmental problems including climate change. It introduces a new framework called Planetary Accounting, which allows the Planetary Boundaries, non-negotiable limits for the environment, to be translated into limits for human activity. It shows how such limits can be broken down into chunks that can be managed at different levels (from individual and community, to business and sector levels, to cities and regions), and at any level of government. The book begins by summarising the science of climate change and introducing the notion of the Anthropocene – the “human age”. It highlights the importance of returning to and remaining within the Planetary Boundaries but shows that we can’t realistically do so unless we have a new approach to environmental accounting. The book then outlines how Planetary Accounting furnishes this new approach by combining sustainability science, change theory, and environmental accounting to create a scalable framework for environmental management that encourages systemic and individual change. The details of the science of and our human contribution to ten critical human pressures are then presented, and the book concludes with a guide for those seeking to apply Planetary Accounting in practice. Planetary Accounting could form the scientific underpinning of behaviour change programs, guide the development of policy and regulations, and provide both the basis for environmental laws, and the foundation of future global environmental agreements. It has been 50 years since the first views from space showed a blue planet alone in our solar system. This book is an historic opportunity to provide humanity for the first time with sufficient information to begin implementing Planetary Accounting.
The UK welfare state is under sustained ideological and political attack. In All Our Welfare, Peter Beresford explores the establishment and trajectory of the postwar welfare state and offers a blueprint for participatory social policy in the future. By showing that early welfare policies resulted from popular revulsion against the inequity of the market and associated poor laws, Beresford reveals that the welfare state was ultimately undermined by its failure to engage the people it was intended to help. Noting the subsequent similar failure of neoliberal social policy to engage people in improving their own welfare, Beresford draws on the pioneering theories and practices of current welfare service user movements to outline participatory approaches to social policy theory, knowledge development, policy, practice, and support, identifying a series of principles that could underpin them and offering inclusive models for sustainable change. Also including fascinating vignettes from his own family's experience, Beresford demonstrates the value of user knowledge.
The study of human reproductive ecology represents an important new development in human evolutionary biology. Its focus is on the physiology of human reproduction and evidence of adaptation, and hence the action of natural selection, in that domain. But at the same time the study of human reproductive ecology provides an important perspective on the historical process of human evolution, a lens through which we may view the forces that have shaped us as a species. In the end, all actions of natural selection can be reduced to variation in the reproductive success of individuals.Peter Ellison is one of the pioneers in the fast growing area of reproductive ecology. He has collected for this volume the research of thirty-one of the most active and influential scientists in the field. Thanks to recent noninvasive techniques, these contributors can present direct empirical data on the effect of a broad array of ecological, behavioral, and constitutional variables on the reproductive processes of humans as well as wild primates. Because biological evolution is cumulative, however, organisms in the present must be viewed as products of the selective forces of past environments. The study of adaptation thus often involves inferences about formative ecological relationships that may no longer exist, or not in the same form. Making such inferences depends on carefully weighing a broad range of evidence drawn from studies of contemporary ecological variation, comparative studies of related taxonomies, and paleontological and genetic evidence of evolutionary history. The result of this inquiry sheds light not only on the functional aspects of an organism's contemporary biology but also on its evolutionary history and the selective forces that have shaped it through time.Encompassing a range of viewpoints--controversy along with consensus--this far-ranging collection offers an indispensable guide for courses in biological anthropology, human biology, and primatology, along with
Drawing on an innovative project exploring current mobility transition policies and practices in 14 countries around the world, including key institutions such as the European Union and the United Nations, this book provides a critique of current transitions, mobility and transport policies. The authors consider how our mobility futures have been imagined, what they will potentially look and feel like, what lives we might live in them and what choices we might have to make to get there.
The Arctic is one of the world’s regions most affected by cultural, socio-economic, environmental and climatic changes. This book offers key insights into the history, current state of knowledge and the future of sustainability, and sustainable development, research in the Arctic. Written by an international, interdisciplinary team of experts, i
INTERNATIONAL BESTSELLER • Far more than a history of the Silk Roads, this book is truly a revelatory new history of the world, promising to destabilize notions of where we come from and where we are headed next. "A rare book that makes you question your assumptions about the world.” —The Wall Street Journal From the Middle East and its political instability to China and its economic rise, the vast region stretching eastward from the Balkans across the steppe and South Asia has been thrust into the global spotlight in recent years. Frankopan teaches us that to understand what is at stake for the cities and nations built on these intricate trade routes, we must first understand their astounding pasts. Frankopan realigns our understanding of the world, pointing us eastward. It was on the Silk Roads that East and West first encountered each other through trade and conquest, leading to the spread of ideas, cultures and religions. From the rise and fall of empires to the spread of Buddhism and the advent of Christianity and Islam, right up to the great wars of the twentieth century—this book shows how the fate of the West has always been inextricably linked to the East. Also available: The New Silk Roads, a timely exploration of the dramatic and profound changes our world is undergoing right now—as seen from the perspective of the rising powers of the East.
The leading reference on this topic has just gotten better. Building on the success of the previous two editions, all the chapters have been updated to reflect the latest developments in the field, and new chapters have been added on picolinic acids, oxathiapiprolin, flupyradifurone, and other topics. This third edition presents the most important active ingredients of modern agrochemicals, with one volume each for herbicides, fungicides, and insecticides. The international team of first-class authors from such renowned crop science companies as Bayer, Syngenta, Dow AgroSciences, DuPont (now Corteva Agriscience), and BASF, address all crucial aspects from the general chemistry and the mode of action to industrial-scale synthesis, as well as from the development of products and formulations to their application in the field. A comprehensive and invaluable source of timely information for all of those working in modern biology, including genetics, biochemistry and chemistry, and for those in modern crop protection science, whether governmental authorities, researchers in agrochemical companies, scientists at universities, conservationists, or managers in organizations and companies involved in improvements to agricultural production.
Pollution damages materials, but it has changed dramatically in the past century, with a reduction in the concentration of corrosive primary pollutants in urban atmospheres. At the same time, architectural styles and types of materials have changed, as we have moved to more organically rich, photochemically active atmospheres. Contemporary pollutants have a greater potential to degrade organic coatings and polymers, which are of great importance to modern structures.Urban Pollution and Changes to Materials and Building Surfaces examines a range of materials, discussing the ways in which they are likely to be damaged by contemporary urban pollutants, with an emphasis on the effects of air pollution. A chapter on graffiti is also included.The wide scope covered means that this volume is suitable for readers from a broad background. It should be of interest to scientists and policymakers dealing with the effects of urban pollution, as well as undergraduate and graduate students working in this area.This book, with its wealth of information, is of exceedingly good value for readers who seek to understand more on the changes of materials and building surfaces by urban pollution.
A group of special interest to mammalogists, taxonomists, and systemicists, ungulates have proven difficult to classify. This comprehensive review of the taxonomic relationships of artiodactyls and perissodactyls brings forth new evidence in order to propose a theory of ungulate taxonomy. With this straightforward volume, Colin Groves and the late Peter Grubb cut through previous assumptions to define ungulate genera, species, and subspecies. The species-by-species accounts incorporate new molecular, cytogenetic, and morphological data, as well as the authors’ own observations and measurements. The authors include references and supporting arguments for new classifications. A starting point for further research, this book is sure to be discussed and hotly debated in the mammalogical community. A well-reasoned synthesis, Ungulate Taxonomy will be a defining volume for years to come.
This book offers a comprehensive and engaging introduction to the criminal justice system of England and Wales. Starting with an overview of the main theories of the causes of crime, this book explores and discusses the operation of the main criminal justice agencies including the police, probation and prison services and the legal and youth justice systems. The fourth edition has been revised, updated, expanded and features a new expert co-author. This book offers a lively and critical discussion of some of the main themes in criminal justice, from policy-making and crime control, to diversity and discrimination, to the global dimensions of criminal justice, including organised crime and the role performed by transnational policing organisations to combat it. Key updates to this new edition include: increased discussion of the measurement, prevention and detection of crime; a revised chapter on the police which discusses the principle of policing by consent, police methods, power and governance, and the abuse of power; further discussion of pressing contemporary issues in criminal justice, such as privatisation, multi-agency working, community-based criminal justice policy and the impact of the Covid-19 pandemic on the delivery of criminal justice policy; a revised chapter that deals in detail with new and emerging forms of criminality and the response of the UK and global criminal justice system to these developments. This accessible text is essential reading for students taking introductory courses in criminology and criminal justice. A wide range of useful features include review questions, lists of further reading, timelines of key events and a glossary of key terms.
Sustainability is a pressing concern for people and governments around the world, but it is also an essentially contested concept that requires an understanding of the stakes, trade-offs, and complex politics at play. Sustainability: The Basics offers an accessible and interdisciplinary introduction to the concept, and discusses key questions such as: What are the core principles of sustainability? What are the key ethical considerations for questions of sustainability? How do we measure sustainability? What are the critical obstacles to achieving global sustainability? What happens when societies fail to observe principles of sustainability? Fully updated in its second edition, Sustainability: The Basics now includes coverage of the Sustainable Development Goals, a global range of case studies and explores the complex social dynamics of Earth system changes that affect our critical life supports. The second edition also proposes a new, "sustainable humanism" that animates much of our work to make a better, more humane world. As the world reels from the effects of the Covid-19 pandemic, this book is an ideal starting point for anyone who wants to know more about what we need to do to sustain civilization, humanity, and the world we live in.
Science produces fascinating puzzles: why is there such a range of placental structures when other mammalian organs are so structurally uniform ? Why and how did the different placental structures evolve ? Comparative placental studies can facilitate the identification of the common factors in placental growth, differentiation and function and their relevance to possible evolutionary pathways. Comparative Placentation is the only book presenting up-to-date data illustrating the great variety of structure but uniform function of vertebrate placentas from fish to man. This information is essential for selection of suitable models to investigate particular practical problems of impaired or anomalous growth in human and animal placentation. The unique collection of the best light and electron micrographs from the last thirtyfive years which precisely illustrate the structural range in each taxon, make the book the most authoritative publication in this field and a vital source of information for anyone interested on reproductive physiology, anatomy and medicine.
A relational approach to the study of interpersonal communication Close Encounters: Communication in Relationships, Fifth Edition helps students better understand their relationships with romantic partners, friends, and family members. Bestselling authors Laura K. Guerrero, Peter A. Andersen, and Walid A. Afifi offer research-based insights and content illustrated with engaging scenarios to show how state-of-the-art research and theory can be applied to specific issues within relationships—with a focus on issues that are central to describing and understanding close relationships. While maintaining the spotlight on communication, the authors also emphasize the interdisciplinary nature of the study of personal relationships by including research from such disciplines as social psychology and family studies. The book covers issues relevant to developing, maintaining, repairing, and ending relationships. Both the "bright" and "dark" sides of interpersonal communication within relationships are explored.
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