Snow in the Tropics by Thomas Taro Lennerfors and Peter Birch offers the first comprehensive history of the independent reefer operators. These shipping companies, such as Lauritzen, Salén, Seatrade, Star Reefers, and NYK Reefer, developed the dedicated transport of refrigerated products like meat, fish, and fruit by ship, from the early 20th century to the present. Snow in the Tropics describes how the history of the reefer operators has been formed in relation to shippers, such as Dole and Chiquita, in a constant struggle with the liner companies, such as Maersk, and in relation to global economic and political trends. It also covers how the industry is discursively constructed and the psychological drivers of the business decisions in it.
The shipping industry has an impact on each and every one of us every day. Ships transport the food we eat, the clothes we wear, the cars we drive, the materials used to build our homes, and the fuel that heats them. Yet traditional shipping companies - ones that combine various aspects of shipping under one organizational roof - are on the decline. They are gradually being replaced by new, more specialized companies with more strategic clarity and managerial focus. In Shipping Strategy Peter Lorange draws on his extensive experience in the shipping industry to show how companies can adapt to the fast-moving and volatile world of maritime business by devising strategies for future success, including specialization and innovation.
This book is intended for anyone, regardless of discipline, who is interested in the use of statistical methods to help obtain scientific explanations or to predict the outcomes of actions, experiments or policies. Much of G. Udny Yule's work illustrates a vision of statistics whose goal is to investigate when and how causal influences may be reliably inferred, and their comparative strengths estimated, from statistical samples. Yule's enterprise has been largely replaced by Ronald Fisher's conception, in which there is a fundamental cleavage between experimental and non experimental inquiry, and statistics is largely unable to aid in causal inference without randomized experimental trials. Every now and then members of the statistical community express misgivings about this turn of events, and, in our view, rightly so. Our work represents a return to something like Yule's conception of the enterprise of theoretical statistics and its potential practical benefits. If intellectual history in the 20th century had gone otherwise, there might have been a discipline to which our work belongs. As it happens, there is not. We develop material that belongs to statistics, to computer science, and to philosophy; the combination may not be entirely satisfactory for specialists in any of these subjects. We hope it is nonetheless satisfactory for its purpose.
Over the past twenty years, there's been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting 'probabilistic genotyping' to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience - Covers short tandem repeat (STR) analysis, including database searching and massive parallel sequencing (both STRs and SNPs) - Encourages dissemination and understanding of probabilistic genotyping by including practical examples of varying complexity - Written by authors intimately involved with software development, training at international workshops and reporting cases worldwide using the methods described in this book
Fully updated to meet the demands of the 21st-century surgeon, Plastic Surgery provides you with all the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Edited by Drs. Mathes and Hentz in its last edition, this six-volume plastic surgery reference now features new expert leadership, a new organization, new online features, and a vast collection of new information - delivering all the state-of-the-art know-how you need to overcome any challenge you may face. Renowned authorities provide evidence-based guidance to help you make the best clinical decisions, get the best results from each procedure, avoid complications, and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in every area of plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Master the latest on stem cell therapy, tissue engineering, and inductive therapies • aesthetic surgical techniques and nonsurgical treatments • conjoined twin separation and other craniofacial surgery advances • microsurgical lymphatic reconstruction, super microsurgery, and sternal fixation • autologous lipofilling of the breast • nerve transfers in hand surgery, hand allotransplantation, and functional prosthetics • and much, much more. Easily find the answers you need with a new organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity, plus a more templated, user-friendly, high-yield presentation. Visualize procedures more clearly through an abundance of completely redrawn full-color illustrations and new color clinical photographs. Access the complete, fully searchable contents of each volume online, download all the tables and figures, view 160 procedural videos, and take advantage of additional content and images at www.expertconsult.com!
Fully updated to meet the demands of the 21st-century surgeon, Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery, Volume 3 of Plastic Surgery, 3rd Edition, provides you with the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in craniofacial, head, neck, and pediatric plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Purchase this volume individually or own the entire set, with the ability to search across all six volumes online! Master the newest procedures in pediatric plastic surgery, including conjoined twinning. Apply the latest clinical evidence and surgical techniques to facilitate the decision-making process for craniofacial patients, and optimize outcomes in the correction of congenital, oncologic, traumatic, and acquired deformities. Know what to look for and what results you can expect with over 2,000 photographs and illustrations. See how to perform key techniques with 28 surgical videos online. Access the complete, fully searchable contents online, download all the tables and figures, and take advantage of additional content and images at www.expertconsult.com!
This volume critically and objectively analyses the literature up to 1989 and presents a guide to the practical use of all calcium antagonists which have been thoroughly investigated to date. It begins with a concise review of physiological principles as a basis for a discussion of the general and specific pharmacodynamics and pharmacokinetics of calcium antagonists. Special emphasis is given to their therapeutic use in practice, precise dosage schedules are provided, interactions with other medications described, and therapeutic alternatives considered.
Peter Adamson presents an engaging and wide-ranging introduction to two great intellectual cultures: Byzantium and the Italian Renaissance. First he tells the story of philosophy in the Eastern Christian world, from the 8th century to the 15th century, then he explores the rebirth of philosophy in Italy in the era of Machiavelli and Galileo.
This thesis is concerned with intention recognition for a humanoid robot and investigates how the challenges of uncertain and incomplete observations, a high degree of detail of the used models, and real-time inference may be addressed by modeling the human rationale as hybrid, dynamic Bayesian networks and performing inference with these models. The key focus lies on the automatic identification of the employed nonlinear stochastic dependencies and the situation-specific inference.
International Civil Litigation in United States Courts, by Gary B. Born and Peter B. Rutledge, is the essential, comprehensive law school text for the current and future international litigator, whether based in the United States, Europe, or elsewhere. Examiningevery topic discussed in competing texts with extensive narrative, unparalleled notes, and detailed citations, this book covers the gamut of international dispute resolution, whether judicial jurisdiction, sovereign immunity, extraterritoriality, conflicts of law, parallel proceedings, discovery disputes, service, judgment enforcement, and international arbitration. This Seventh Edition includes excerpts and updated discussions of recent U.S. court decisions and legislation relating to a wide range of private and public international law topics. New to the SeventhEdition: Latest developments in litigation under the Alien Tort Statute and the Torture Victim Protection Act Latest developments in sovereign immunity law following several landmark Supreme Court decisions Latest developments regarding the extraterritorial application of federal law following several landmark Supreme Court decisions Critical examination of the new Restatement (Fourth) of the Foreign Relations of the United States Up-to-date citation and review of the most current academic legal scholarship in the field Professors and students will benefit from: Detailed notes with easy-to-use questions for discussion and legal analysis Comprehensive discussion of international dispute resolution, including international arbitration and other forms of dispute resolution outside of litigation in national courts Comparative foreign treatment of selected issues of international civil procedure Extensive notes and up-to-date citations that ensure the book has enduring value long after a course has ended, and it becomes a resource for practitioners seeking to research the field Documentary Supplement
Surgery, 3rd Edition, provides you with the most current knowledge and techniques hand and upper extremity plastic surgery, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients' expectations.
Britain’s foremost scholar of the international shipping industry, based at the Centre for Port and Maritime History, University of Liverpool, here examines the growth and development of Japan’s modern shipping and shipbuilding industries across a wide range of topics, through the pre-war, Pacific War and post-war periods, to the transfer of shipping technology, the role of bulk carriers and world trade and the organization and structure of the Japanese merchant navy. Prompted originally by his research into the decline of the British industries in a global context, his focus inevitably turned to Japan which in the post-war years had replaced Britain as the world’s largest ship operators and ship owners and remains so today.
Peter Straub masterfully weaves horror and suspense into a love story unlike any other: the ballad of Ballard and Sandrine. Ballard and his considerably younger lover Sandrine have been brought together by a shared erotic obsession of the darkest kind. As they travel down a remote part of the Amazon River on a luxurious yacht, they spend their days indulging in their macabre pastime. Through a haze of pain and pleasure, the lovers are witness to a series of increasingly sinister portents, dreams and visions that haunt their claustrophobic and disturbing world. With Peter Straub’s signature, breathtaking twists and an astonishing climax, you’ll never forget The Ballad of Ballard and Sandrine.
International Trade Law offers a clear overview of the complexities of an international sale transaction through informed analysis of case law, legislation, and international conventions and rules. Fully updated with changes to the law and new directions in legal debate, this new edition considers: Standard trade terms including INCOTERMS 2010, the Convention on International Sales of Goods 1980 and the UNIDROIT Principles for International Commercial Contracts E-Commerce issues, including electronic bills of lading Insurance and payment mechanisms, such as letters of credit and the UCP 600 International transportation of cargo, including the Rotterdam Rules Dispute resolution (including jurisdiction, applicable law, arbitration and mediation), with particular reference to the relevant EU regulations and the developing case-law thereon Corruption and anti-corruption conventions, including the UK Bribery Act 2010 and developments relating to deferred prosecution agreements In addition to clarifying a range of topics through tables and diagrams, the book directs readers to relevant further reading and online resources throughout, offering students an accessible resource to this often challenging area of the law.
This book focuses on informed consent in African Traditional Medicine (ATM). ATM forms a large portion of the healthcare systems in Africa. WHO statistics show that as much as 80% of the population in Africa uses traditional medicine for primary health care. With such a large constituency, it follows that ATM and its practices should receive more attention in bioethics. By comparing the ethics of care approach with the ATM approach to Relational Autonomy In Consent (RAIC), the authors argue that the ATM focus on consent based on consensus constitutes a legitimate informed consent. This book is distinctive insofar as it employs the ethics of care as a hermeneutic to interpret ATM. The analysis examines the ethics of care movement in Western bioethics to explore its relational approach to informed consent. Additionally, this is the first known study that discusses healthcare ethics committees in ATM.
Bike racers were America’s media darlings less than a century ago—dashing, eccentric, and very rich daredevils. Until the 1920s bike races drew larger crowds than all other American sports events, including Major League Baseball games. Prize-winning racer and journalist Peter Joffre Nye vividly re-creates this period of sports history, forgotten until now, in Hearts of Lions, a true story of courage, daring, and occasional lunacy. Revised, updated, and expanded, this second edition of Hearts of Lions is based on interviews with more than one thousand cyclists whose racing careers span from 1908 through the 2016 Rio Olympics, along with interviews with trainers and family members. Included are stories about Joseph Magnani, the lone American from southern Illinois who rode on the dusty roads of Europe in road racing’s golden era of the 1930s and 1940s; Lance Armstrong, whose rise in the mid-1990s was eclipsed in the doping era that still casts a long shadow over the sport; Kristin Armstrong, a three-time Olympic gold medalist who set new standards for women in cycling; and Evelyn “Evie” Stevens, who chucked a Wall Street career in her mid-twenties to compete in two Olympics and win several world championship gold medals. Hearts of Lions is a colorful, exciting, classic work on the art of bicycle racing over 140 years against a backdrop of social, political, and technical changes.
Modern statistics deals with large and complex data sets, and consequently with models containing a large number of parameters. This book presents a detailed account of recently developed approaches, including the Lasso and versions of it for various models, boosting methods, undirected graphical modeling, and procedures controlling false positive selections. A special characteristic of the book is that it contains comprehensive mathematical theory on high-dimensional statistics combined with methodology, algorithms and illustrations with real data examples. This in-depth approach highlights the methods’ great potential and practical applicability in a variety of settings. As such, it is a valuable resource for researchers, graduate students and experts in statistics, applied mathematics and computer science.
NORWEGIAN FOLK TALES were collected and published in the mid 19th century by Peter Christian Asbjørnsen (1812-1885) and Jørgen Moe (1813-1882). The folk tales were early on illustrated by our leading artists, and contributed to the development of a national identity. The book contains 20 of the most wellknown folk tales, such as: White-Bear-King-Valemon, Little Freddie and his Fiddle, The Seventh Father of the House, The Princess who Always had to have the Last Word. NORWEGIAN HERITAGE is a series of books about our most important and best-known national icons. The respective titles introduce major personalities from the worlds of art and literature, science and sports, but also the many natural wonders of the country, as well as significant historical periods and cultural expressions. Each book offers an updated introduction to readers who wish to familiarize themselves with a given subject.
This is a clinical neurology book for the student, non neurologist, and those that teach them. The book covers neuroanatomy, history taking and examination and then proceeds to discuss the clinical features of common problems as well as some of the more common rare, neurological disorders, in a way that will demystify a part of medicine that students find complex and difficult to understand. The book is accompanied by a DVD explaining concepts, demonstrating techniques of performing the neurological examination and demonstration of abnormal neurological signs. The first chapter is devoted to neuroanatomy from a clinical viewpoint. The concept of localising problems by likening the nervous system to a map grid with vertical meridians of longitude (the ascending sensory pathways and the descending motor pathway)and horizontal parallels of latitude (cortical signs, brainstem cranial nerves, nerve roots and peripheral nerves) of the nervous system is developed. Subsequent chapters take the reader through the neurological examination and the common neurological presentations from a symptom oriented approach. Chapter 4 contains a very simple method of understanding the brainstem, the "rule of 4". Chapter 6 discusses the approach after the history and examination are completed. The final chapter is an overview of how to approach information gathering and keeping up-to-date using the complex information streams available. - widely illustrated with case studies and illustrations - key points - clinical questions - clinical orientation with comprehensive references
A self-contained introduction to probability, exchangeability and Bayes’ rule provides a theoretical understanding of the applied material. Numerous examples with R-code that can be run "as-is" allow the reader to perform the data analyses themselves. The development of Monte Carlo and Markov chain Monte Carlo methods in the context of data analysis examples provides motivation for these computational methods.
Artificial intelligence: A Modern Approach, 3e,is ideal for one or two-semester, undergraduate or graduate-level courses in Artificial Intelligence. It is also a valuable resource for computer professionals, linguists, and cognitive scientists interested in artificial intelligence. The revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence.
Comprehensive and fully up to date, Dr. Peter Neligan's six-volume masterwork, Plastic Surgery, 5th Edition, remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, it features new, full-color clinical photos, procedural videos, and lectures across all six volumes. Bonus material online includes additional text, images, and over 200 procedural videos that help you improve your mastery of the latest techniques. - Easily find the answers you need with an organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity. Each easily readable, individual volume is a standalone comprehensive text full of salient and applicable anatomy and techniques. - Key procedures include gender affirmation management and surgery, microsurgery and surgery for lymphedema, aesthetic facial surgery, aesthetic body surgery, and the education, training and practice of plastic surgery. - New digital video preface by Dr. Neligan addresses the changes across all six volumes. - New treatment and decision-making algorithms added to chapters where applicable. - New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. - Four new international experts join the editorial team, and lead editor Peter C. Neligan creates a cohesive tone throughout the chapters and content across all six volumes. - Evidence-based advice from a diverse collection of experts allows you to apply the very latest advances in every area of plastic surgery and ensure optimal outcomes. - Purchase only the volumes you need or own the entire set, with the ability to search across all six volumes online!
Although there appears to be a general understanding that the human brain functions similarly in women and in men, an increasing body of knowledge indicates that neuronal connectivity, recruitment, and disease patterns exhibit gender differences. There are clear gender differences in genetic expression, physiologic function, metabolism, hormonal makeup, and psychosocial profile, which often modify the clinical expression of neurologic and other diseases. In addition, ethnic, cultural, and economic factors are frequently overlooked in dealing with health problems of women, even though they undoubtedly have a strong influence on the clinical course of the illness. The second edition of Neurologic Disease in Women, the only text to specifically cover this important topic, will help physicians and other medical personnel seeking information relevant to clinical care. Sections address general anatomic, hormonal, epidemiologic, and drug aspects of women's health; neurologic conditions that arise during childhood, pregnancy, adulthood, and old age in females; and particular neurologic conditions that present differently or predominantly in females. There have been important advances in several areas prompting new chapters, new approaches and additional information provided in chapters on hormonal effects in women and the use of HRT; the adverse effects of antiepileptic drugs on hormonal homeostasis, weight and bone health; and cardiovascular diseases in women. New chapters include ones on reproductive and metabolic disorders with AED use, and on movement disorders.
Many patients referred for an epilepsy evaluation actually suffer from one of many conditions that can imitate it. Imitators of epilepsy are a diverse group that involve consideration of many areas of internal medicine, neurology, and psychiatry. The most important imitators of epileptic seizures are dizziness, vertigo, syncope, complicated migraine; and somewhat less frequently sleep disorders, transient cerebral ischemia, paroxysmal movement disorders, endocrine or metabolic dysfunction, delirium, psychiatric conditions or transient global amnesia. Clearly under-recognized are hyperventilation episodes, panic attacks, and other psychogenic and psychiatric paroxysmal disorders that may simulate epileptic seizures. This volume provides a comprehensive review of the differential diagnosis of seizures: how do the imitators of epilepsy present clinically, what are their particular distinguishing historical features, and what tests are helpful with diagnosis? Expanding beyond the first edition, this second edition is divided into four sections. The first deals with an introduction and approach diagnosing spells, the electroencephalography of epilepsy and its imitators, and specialized tests of diagnosis such as measurement of serum prolactin. There are chapters on epileptic seizures that do not look like typical epileptic seizures, and conversely, apparent epileptic seizures that are not. A second section approaches imitators of epileptic seizures along age-based lines; i.e., what sorts of spells are likely to beset infants, children, or the elderly? A third section addresses individual imitators of epilepsy, ranging from the common to the rare, from dizziness and faintness to startle disease, arranged according to whether they might simulate partial, generalized, or both types of epileptic seizures. The volume finishes off with hyperventilation syndrome, psychogenic seizures (with or without epilepsy), and panic disorders. Most chapters review the basic definitions and physiology of the respective imitator, followed by the clinical characteristics. Emphasis is given to those features that may differentiate it from an epileptic event, but also mark it for what it is, and give possible criteria for an alternate diagnosis. Case vignettes are used to illustrate particular aspects, along with tables that compare and contrast phenotypically similar conditions. Based on their extensive clinical experience, the authors provide a personal perspective on diagnosis and treatment.
Comprehensive and fully up to date, the six-volume Plastic Surgery remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery, Volume 3 of Plastic Surgery, 5th Edition, features new, full-color clinical photos, procedural videos, lectures, and authoritative coverage of hot topics in the field. Editor-narrated video presentations offer a step-by-step audio-visual walkthrough of techniques and procedures. - New chapters cover surgical management of facial pain, facial feminization, idiopathic progressive hemifacial atrophy, and cleft palate; coverage throughout includes new, pioneering translational work shaping the future of craniofacial, head and neck, and pediatric plastic surgery. - New digital video preface by Dr. Peter C. Neligan addresses the changes across all six volumes. - New treatment and decision-making algorithms added to chapters where applicable. - New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. - Evidence-based advice from an expanded roster of international experts allows you to apply the very latest advances in hand and upper extremity plastic surgery and ensure optimal outcomes. - Purchase this volume individually or own the entire set, with the ability to search across all six volumes online! - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.
Despite the fact that Athenians consumed great quantities of manufactured goods, and around half of the residents of classical Athens can be shown to have been more or less dependent for survival on manufacturing in some form, this subject has been almost completely neglected by historians. Poiesis brings together ancient texts and inscriptions, recent scholarly analysis, archaeological finds, and the expertise of modern craftsmen to investigate every known facet of Athens' manufacturing activities. Authored by a management consultant and a recent PhD in Ancient History, the book presents the information in terms of contemporary business principles, drawing on supply and demand and risk-return analysis to explain events and choices. Manufacturing operations are classified in a novel framework based on competitive advantage and barriers to entry, concepts previously absent from ancient history. The framework explains why certain segments were suited to the sole craftsman and others to teams of slaves, and deduces earnings potential based upon competitive differentiation. The result is a new angle on how Athenian society operated; in particular it shows how fragmented industry structures, often the result of primitive technology, were fundamental to the workings of the Athenian democracy by enabling citizens to supplement their income through casual manufacturing activity. The book explains how manufacturing for sale emerged from autarchic peasant households, explores whether any of the industries examined changed to any great extent in Hellenistic and Roman times, and shows how some were transformed by the Industrial Revolution. It includes a methodology for quantifying the demographics of participation in manufacturing. By presenting a new paradigm of historical analysis, one complementing political, military, and literary perspectives, the book will be valuable to classicists and ancient and economic historians.
Recent explorations in the neurosciences have been progressing towards an understanding of the relationship between brain struc ture and brain function. Having passed through an era which may be described as one of a localisationist philosophy, in which discrete brain areas were seen to subserve only discrete functions, the perspective of brain-behaviour relationships has advanced in recent years to an appreciation that a more holistic approach is not only heuristically valid, but is also most likely to lead to future advances. The close relationship between the mind and the brain has been appreciated since the time of Hippocrates when he opined 'men ought to know that from nothing else but thence [from the brain] comes joys, delights, laughter and sports, and sorrows, griefs, despondency and lamentations ... and by this same organ we become mad and delirious and fears and terrors assail us'. In the nineteenth century, particularly in France and Germany, descrip tions of what are now recognised to be independent neurological diseases emerged following empirical clinical observations. Investi gation led to the identification in many cases of underlying struc tural abnormalities which could be linked to pathological changes.
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