For the last 30 years, polyphenols were in the centre of research work worldwide. Silymarin, an extract from a medicinal plant Silybum marianum, also known as milk thistle, has a special place in this group, having been used in human medicine for the management of liver diseases since ancient times. Accumulating scientific evidence indicates that silymarin is characterised by a wide range of protective pharmacological activities and this topic has received tremendous attention in recent years. However, until now there has been no single monograph addressing major questions related to silymarin chemistry, biochemistry and practical applications. The goal of this book is to provide up to date information about silymarin chemistry, biochemistry and molecular mechanisms of protective actions of this phytochemical with a special emphasis to its vitagene- and transcription factor-modulating properties. Silymarin applications in human diseases, including hepatoprotection, neuroprotection, anti-diabetic, anti-arthritis and other protective activities are reviewed. Immunomodulating, anti-inflammatory, anti-toxic protective activities of silymarin are characterised in detail. Practical applications of silymarin in poultry and animal industry with a special emphasis on its protective roles in gut health maintenance are also presented. This book will be of practical importance to medical and pharmaceutical scientists, including medical doctors, pharmacists, consultants, etc. as well as to poultry/animal scientists, poultry producers, nutritionists and vets, as well as to students of medical, biological and agricultural backgrounds. It can also be of interest for researchers in areas related to physiology, biochemistry, nutrition and veterinary medicine.
The Action Plan for Australian Mammals 2012 is the first review to assess the conservation status of all Australian mammals. It complements The Action Plan for Australian Birds 2010 (Garnett et al. 2011, CSIRO Publishing), and although the number of Australian mammal taxa is marginally fewer than for birds, the proportion of endemic, extinct and threatened mammal taxa is far greater. These authoritative reviews represent an important foundation for understanding the current status, fate and future of the nature of Australia. This book considers all species and subspecies of Australian mammals, including those of external territories and territorial seas. For all the mammal taxa (about 300 species and subspecies) considered Extinct, Threatened, Near Threatened or Data Deficient, the size and trend of their population is presented along with information on geographic range and trend, and relevant biological and ecological data. The book also presents the current conservation status of each taxon under Australian legislation, what additional information is needed for managers, and the required management actions. Recovery plans, where they exist, are evaluated. The voluntary participation of more than 200 mammal experts has ensured that the conservation status and information are as accurate as possible, and allowed considerable unpublished data to be included. All accounts include maps based on the latest data from Australian state and territory agencies, from published scientific literature and other sources. The Action Plan concludes that 29 Australian mammal species have become extinct and 63 species are threatened and require urgent conservation action. However, it also shows that, where guided by sound knowledge, management capability and resourcing, and longer-term commitment, there have been some notable conservation success stories, and the conservation status of some species has greatly improved over the past few decades. The Action Plan for Australian Mammals 2012 makes a major contribution to the conservation of a wonderful legacy that is a significant part of Australia’s heritage. For such a legacy to endure, our society must be more aware of and empathetic with our distinctively Australian environment, and particularly its marvellous mammal fauna; relevant information must be readily accessible; environmental policy and law must be based on sound evidence; those with responsibility for environmental management must be aware of what priority actions they should take; the urgency for action (and consequences of inaction) must be clear; and the opportunity for hope and success must be recognised. It is in this spirit that this account is offered.
Law in the United States, Second Edition, is a concise presentation of the salient elements of the American legal system designed mainly for jurists of civil law backgrounds. It focuses on features of American law likely to be least familiar to jurists from other legal traditions, such as American common law, the federal structure of the U.S. legal system, and the American constitutional tradition. The use of comparative law technique permits foreign jurists to appreciate the American legal system in comparison with legal systems with which they are already familiar. Chapters in the second edition also cover such topics as American civil justice, criminal law, jury trial, choice of laws and international jurisdiction, the American legal profession, and the influence of American law in the global legal order.
Attuned to the complexities of real-world clinical situations, this authoritative volume belongs on the desks of practitioners, researchers, and students in clinical and counseling psychology, psychiatry, and social work, as well as health care administrators and planners. In the classroom, it serves as a uniquely informative text in advanced undergraduate- and graduate-level courses in psychotherapy research and clinical practice."--BOOK JACKET.
This acclaimed work provides a systematic, comprehensive, and balanced evaluation of the current status of all major psychotherapeutic approaches. With a primary focus on adults, detailed evidence is presented for the efficacy of widely used interventions for frequently encountered mental disorders and specific populations. The book also explains the concepts that underpin psychotherapy research, examines methodological challenges in translating research into practice, and considers the impact on outcome of factors common to all therapies, such as therapist and patient characteristics.
Glasgow, April 1820. The last armed uprising on British soil, intent on severing the Union and establishing a radical Scottish republic, ended in executions, imprisonments, transportations and 85 trails for high treason. Yet despite its political and social importance, the story of this working-class revolution vanished from the historical record. This book restores the radical rising to its rightful place in history, offering an incisive analysis of the rising itself and the events which led up to it, vividly recapturing the extraordinary heroism of its leaders, John Baird and Andrew Hardie, and the savagery with which the movement was crushed by the forces of the British state.
This is a highly visual, case-based approach that covers the spectrum of the clinical presentation of heart failure. Each chapter revolves around one or more cases that best represent the diagnosis and treatment of a specific type of heart failure. The book encompasses newly diagnosed cases of heart failure, optimizing therapy for patients with known heart failure, heart failure associated with a variety of cardiac diseases, and heart failure in patients with systemic diseases. Authors also address the rapidly expanding field of familial-based cardiomyopathies and the difficult task of determining prognosis. The newly diagnosed cases of heart failure include non-ischemic dilated cardiomyopathy, post-myocardial infarction heart failure, tako-tsubo cardiomyopathy, atrial fibrillation as a cause of heart failure, and manifestations of diastolic dysfunction causing heart failure. The section on optimizing therapy for patients with chronic heart failure encompasses treatment for an initially stabilized patient who begins to decline and presents with an acute exacerbation; treating patients with devices such as defibrillators, resynchronization pacemaker systems, or both; and actions that can be taken when, despite the full gamut of treatment, a patient is still symptomatic or gradually declining. Included is a discussion of hemodynamic optimization and advanced therapy for end-stage failure. Additionally, the book covers in depth procedures for determining prognosis and evaluating familial disease; and includes descriptions of medications commonly used for heart failure. Chapters are consistently formatted to include an overview of underlying pathophysiology, presentation of the representative ìteachingî case, and a discussion of optimal management including assessment of current evidence and guidelines. The book also features video loops of select procedures, available online. KEY FEATURES: Over thirty expert authors offer a practical, visual approach to common but complex management problems in heart failure Demonstrates real-world clinical management decisions and applications of current guidelines and evidence through case presentations Discusses assessment and treatment of newly diagnosed and chronic cases of heart failure Addresses heart failure associated with the gamut of cardiac diseases and in patients with systemic diseases Provides links to video loops of select procedures
Now in a fully updated 9th Edition, Kendig's Disorders of the Respiratory Tract in Children, by Drs. Robert Wilmott, Andrew Bush, Robin Deterding, and Felix Ratjen, continues to provide authoritative, evidence-based information to residents, fellows, and practitioners in this wide-ranging specialty. Bringing key knowledge from global experts together in one easy-to-understand volume, it covers everything from the latest basic science and its relevance to today's clinical issues, to improving patient outcomes for the common and rare respiratory problems found in newborns and children worldwide. - Uses succinct, straightforward text, numerous tables and figures, summaries at the end of each chapter, and more than 500 full-color images to convey key information in an easy-to-digest manner. - Contains new chapters reflecting expanding knowledge on the respiratory complications of Down syndrome and other genetic disorders, modern molecular therapies for cystic fibrosis and asthma, and pulmonary embolism and thromboembolic disease. - Includes access to a new video library with demonstrations of key procedures. - Features a new templated format with more descriptive headings and bulleted text for quick reference and navigation. - Covers today's key issues, including the genetic basis of respiratory disease, new and emerging respiratory infections, interstitial lung diseases in infants and young children, technology and diagnostic techniques for pulmonary function tests, emerging lung infections, and new therapies for cystic fibrosis and asthma. - Provides up-to-date instruction on important procedures, such as bronchoscopy and pulmonary function testing. - Highlights the knowledge and expertise of three new editors, as well as more than 100 world authorities in the fields of pediatrics, pulmonology, neurology, microbiology, cardiology, physiology, diagnostic imaging, critical care, otolaryngology, allergy, and surgery. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Of Rule-Making and Amendment Process -- Federal Rules of Evidence -- General Provisions -- Judicial Notice -- Presumptions in Civil Actions and Proceedings -- Relevancy and Its Limits -- Privileges -- Witnesses -- Opinions and Expert Testimony -- Hearsay -- Authentication and Identification -- Contents of Writings, Recordings, and Photographs -- Miscellaneous Rules -- Amendments to the Federal Rules of Evidence Proposed but Pending Adoption -- Federal Rules of Evidence Adopted by the United States Supreme Court but not Adopted by Congress -- California Evidence Code -- Preliminary Provisions and Construction -- Words and Phrases Defined -- General Provisions -- Judicial Notice -- Burden of Proof; Burden of Producing Evidence; Presumptions and Inferences -- Witnesses -- Opinion Testimony and Scientific Evidence -- Privileges -- Evidence Affected or Excluded by Extrinsic Policies -- Hearsay Evidence -- Writings -- Case Supplement -- Categorical Rules of Exclusion -- Rules of Admissibility in Non-Jury Cases -- Should the Rules of Evidence Be Modified for Civil Non-Jury Trials? / Peter L. Murray, John C. Sheldon -- Evidence of Character -- Wilson v. State -- Competency, Examination, and Credibility of Witnesses -- Evidence and Legal Ethics -- Trial Lawyers' Ethics / Peter L. Murray -- Privileges -- United States v. Hayes.
Revised and updated, this edition covers general principles of overdose management; the automonic nervous system, neurotransmitters and drugs; drugs used in psychiatry; cardiac drugs; agents that burn; gases and abnormal haemoglobin formation; the
In All Things First' looks in detail at 1 Squadron during the Second World War with particular emphasis on the pilots and its operational activities. 1 Squadron was active from a very early stage when it flew to France on 8 September 1939 as part of the Advanced Air Striking Force and played a significant role in the Battle of France. Unlike most other squadrons that fought in France, it also played a major part in the Battle of Britain in 11 Group. Later in the war the Squadron had considerable success in the night intruder role and also took part in the defense against hit-and-run raiders. It was highly active over occupied Europe carrying out Rhubarb and Ramrod operations including the dive bombing of V-1 installations. When the V-1 campaign began 1 Squadron was the highest scoring Spitfire squadron. During the Second World War it flew the Hawker Hurricane from 1939-42 before converting to the Typhoon. In early 1944 it received Spitfire IXs and ended the war with the Griffon-powered Spitfire F.21. The main parts of the book are as follows: 1) Early Days - a brief look at the history of 1 Squadron up to 1939, 2) The First Team - pilot profiles, 3) The Phoney War - Blitzkrieg - The Withdrawal from France, 4) The Battle of Britain, 5) Sweeps and Circuses in 1941, 6) Night Intruders, 7) The Typhoon - combat with Fw 190 Jabos and Ramrods, 8) The Spitfire, 9) The V-1 Campaign and conversion to the Spitfire F.21, 10) The Post War Years - the No.1 Squadron story brought up to date. There will also be extensive appendices to include aircraft losses, details of selected operations and pilot escape and evasion.
Cycling: A Sociology of Vélomobility explores cycling as a sociological phenomenon. Drawing on extensive ethnographic fieldwork, it considers the interaction of materials, competencies and meanings that comprise a variety of cycling practices. What might appear at first to be self-evident actions are shown to be constructed through the interplay of numerous social and political forces. Using a theoretical framework from mobilities studies, its central themes respond to the question of what it is about cycling that provokes so much interest and passion, both positive and negative. Individual chapters consider how cycling has appeared as theme and illustration in social theory, as well as the legacies of these theorizations. The book expands on the image of cycling practices as the product of an assemblage of technology, rider and environment. Riding spaces as material technologies are found to be as important as the machinery of the cycle, and a distinction is made between routes and rides to help interpret aspects of journey-making. Ideas of both affordance and script are used to explore how elements interact in performance to create sensory and experiential scapes. Consideration is also given to the changing identities of cycling practices in historical and geographical perspective. The book adds to existing research by extending the theorization of cycling mobilities. It engages with both current and past debates on the place of cycling in mobility systems and the problems of researching, analyzing and communicating ephemeral mobile experiences.
Over the past ten to fifteen years there has emerged an increasing concern with mobility in the social sciences and humanities. In Mobility, Space and Culture, Peter Merriman provides an important and timely contribution to the mobilities turn in the social sciences, encouraging academics to rethink the relationship between movement, embodied practices, space and place. The book takes an interdisciplinary approach, drawing upon theoretical and empirical work from across the social sciences and humanities to provide a critical evaluation of the relationship between 'mobility' and 'place'/'site', reformulating places as in process, open, and dynamic spatial formations. Merriman draws upon post-structuralist writings on space, practice and society to demonstrate how movement is not simply practised or experienced in relation to space and time, but gives rise to rhythms, forces, atmospheres, affects and materialities which are often more crucial to embodied apprehensions of events than sensibilities of spatiality and temporality. He draws upon detailed empirical research on experiences of, and social reactions to, driving in late Victorian and Edwardian Britain to trace how the motor-car became associated with sensations of movement-space and enmeshed with debates about embodiment, health, visuality, gender and politics. The book will be essential reading for undergraduates and postgraduates studying mobility in sociology, geography, cultural studies, politics, transport studies, and history.
The first edition of How Your Church Family Works was written nearly thirty years ago, and the reach and velocity of change in the last three decades poses a new challenge for churches. Thirty years ago, churches functioned in a fairly stable environment and focused on growth an expansion. The tide has turned now, though, and supplanted increase with decline. Bowen family systems theory—on which How Your Church Family Works is based—has not changed, but its application has to be revised for the twenty-first century. How Your 21st-Century Church Family Works, the second edition of Peter Steinke’s landmark book, addresses the radically altered landscape of church sustainability with new introductory and concluding chapters bookending updates throughout the now-classic text. Core chapters of the book feature fresh examples of emotional process that are more exemplary of the current scene. One key addition is a new trigger of anxiety for churches—the change process. Change threatens the familiar and stable and suffers from negative connotations of endangering tradition. Where gradual change has been the norm for so long, churches now see a blistering pace of disruptions, some of which have forced change too early or too late, or sometimes in unproductive directions. How Your 21st-Century Church family works embraces the anxiety caused by change, transforming it from a source of anguish to a font of opportunity.
A Bestseller Attachment Theory shows scientifically how our earliest relationships with our mothers influence our later relationships in life. This book offers an excellent introduction to the findings of attachment theory and the major schools of psychoanalytic thought. "The book every student, colleague, and even rival theoretician has been waiting for. With characteristic wit, philosophical sophistication, scholarship, humanity, incisiveness, and creativity, Fonagy succinctly describes the links, differences, and future directions of his twin themes. [His book] is destined to take its place as one of a select list of essential psychology books of the decade." -Jeremy Holmes, Senior Lecturer in Psychotherapy, University of Exeter "Extraordinary--an invaluable resource for developmental psychoanalysis." -Joy D. Osofsky, Professor, Louisiana State University
Meningiomas, by M. Necmettin Pamir, MD, Peter M. Black, MD, PhD, and Rudolf Fahlbusch, MD, presents current and comprehensive guidance on this most common, yet clinically challenging type of brain tumor. Written and edited by the world’s most prominent brain tumor neurosurgeons, it helps you to not only determine the type and location of the tumor, but also the most ideal surgical approach to provide your patients with the best outcomes. An extensive collection of surgical photographs covers unique and original cases, while discussions of pre-surgical techniques and approaches emphasize decision making with the help of all imaging modalities and analysis of symptoms and patient history. Expert Consult functionality enhances your reference power with convenient online access to the complete text and illustrations from the book, along with videos that depict surgical techniques in real time. Provides access to the complete text online—fully searchable, along with all of the illustrations downloadable for your personal presentations, and real-time surgical videos covering microscopic extended endonasal approach to suprasellar meningioma, and more, at expertconsult.com. Covers today’s full range of management methods, including adjuvant therapies, providing you with the best strategies for obtaining optimal outcomes. Features the work of the world’s most prominent brain tumor neurosurgeons—a completely international authorship—bringing you the best procedures globally. Offers an in-depth section on surgical methods and approaches based upon tumor location, to help you in the decision-making process. Includes coverage of spinal meningiomas including pre-diagnosis symptoms and outcomes.
Offering a new perspective on adult English language education, this book provides theoretical and practical insights into how digital literacies can be included in the learning programmes for newly arrived adults from migrant and refugee backgrounds. Enhancing Digital Literacies with Adult English Language Learners takes readers inside Langfield, an adult community-based English language centre that supports the settlement and learning of this vulnerable group. Drawing on a six-month ethnographic study of Langfield’s work, the book explores the approach to teaching digital literacies and presents a range of perspectives, including those of the adult learners, the teachers, and the organisation’s CEO. The chapters present a holistic view of teaching digital literacies in the adult English language context by exploring: adult learners’ digital literacy practices in everyday life and their learning at Langfield; teachers' beliefs and practices about digital literacies; and the support offered to them through institutional resources, leadership, and professional learning. The book identifies exemplary practices, as well as areas for further development in Langfield’s work and offers a range of implications for practice, policy, and research. Written in a detailed but accessible manner, this book contributes important insights into the strengths and needs of this unique and complex education sector. Addressing an area of uncertainty for many researchers, practitioners, leaders, and policy makers working within community-based learning contexts in Australia and internationally, this book will be an essential resource.
Duncan Phyfe (1770-1854), known during his lifetime as the "United States Rage," to this day remains America's best-known cabinetmaker. Establishing his reputation as a purveyor of luxury by designing high-quality furniture for New York's moneyed elite, Phyfe would come to count among his clients some of the nation's wealthiest and most storied families. This richly illustrated volume covers the full chronological sweep of the craftsman's distinguished career, from his earliest furniture-- which bears the influence of his 18th-century British predecessors Thomas Sheraton and Thomas Hope--to his late simplified designs in the Grecian Plain. More than sixty works by Phyfe and his workshop are highlighted, including rarely seen pieces from private collections and several newly discovered documented works. Additionally, essays by leading scholars bring to light new information on Phyfe's life, his workshop production, and his roster of illustrious patrons. What unfolds is the story of Phyfe's remarkable transformation from a young immigrant craftsman to an accomplished master cabinetmaker and an American icon."--Publisher's website.
Selenium (Se) is an essential dietary trace element participating in the regulation of various physiological functions in humans and farm animals through its incorporation into a range of selenoproteins. Low Se content in main feed ingredients is a common problem worldwide and dietary Se supplementation is a current practice in ruminant nutrition. Recent research clearly proved that sodium selenite, used for the last 50 years as a feed supplement, is not an optimal form of Se. However, use of organic selenium in dairy and beef diets can help meet Se requirement and maintain health/high immunocompetence, productive and reproductive performance. The goal of this book is to provide up-to-date information about the roles of Se in ruminant nutrition and health. A special emphasis is given to the role of selenium as an essential part of the integrated antioxidant system. The concept of using organic Se in ruminant nutrition is described in detail with emphasis on selenomethionine as a storage form of Se in the body. Also, specific Se deficiency-related disorders in ruminants are described and the importance of Se in growth, development, immunity and reproduction is demonstrated. Molecular mechanisms of protective effects of Se under stressful conditions of commercial milk and meat production are characterized. This book will be of practical importance to dairy and beef producers, to nutritionists and vets as well as for animal scientists, students of agricultural colleges and universities. It will also be of interest for researchers in areas related to environmental sciences, food sciences, physiology, etc.
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