Developments in the field of genetics (including, but not limited to, human genetics) have brought into being (or at least into the realm of plausibility) a genetic engineering which is widely perceived to pose a diverse assortment of intricately tangled and in many respects novel ethical problem
The undisputed gold standard text in the field, Ryan's Retina is your award-winning choice for the most current, authoritative information on new technologies, surgical approaches, scientific advances and diagnostic and therapeutic options for retinal diseases and disorders. Packed with timely updates throughout, new illustrations, and a dedicated team of editors who extend Dr. Ryan’s legacy in retina, this outstanding 6th Edition is a must-have reference for retinal specialists, ophthalmologists, and fellows in training. Offers the most comprehensive content available on retina, balancing the latest scientific research and clinical correlations, covering everything you need to know on retinal diagnosis, treatment, development, structure, function, and pathophysiology. Provides a truly global perspective from five highly esteemed section editors and more than 350 other world authorities from across Europe, Asia, Australasia, and the Americas. Bullets Includes new chapters on widefield imaging, intraoperative OCT imaging, medical management of diabetes mellitus and age-related macular degeneration, and senile retinoschisis. Includes more than 1,150 brand-new illustrations, scans, and photographs throughout. Covers the explosion of new imaging options across optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging, including a greatly expanded OCT imaging chapter that features crucial information on OCT-Angiography (OCT-A). Presents new pharmacotherapy data and the latest approaches in anti-VEGF therapy for age-related macular degeneration, diabetic retinopathy, and venous occlusive disease. Contains thorough content updates in every area of retina, including advanced imaging technologies, gene therapy, inflammation and immune responses, white dot syndromes, epigenetic mechanisms, transplantation frontiers to improve retinal function, macular hole, myopic eye disease, ocular trauma, drug delivery to the posterior segment, advances in macular surgery, vitrectomy and complex retinal detachment, tumors, and retinal genetics and biology.
Macular Surgery, Second Edition serves as a comprehensive and contemporary review of macular diseases and their management. An exhaustive review of the latest proven surgical techniques and therapies for treatment of macular disorders is provided, with emphasis on proven techniques from extensive reviews of controlled clinical trials. Specific chapters of the book are devoted to age-related macular degeneration, diabetic retinopathy, macular holes, epiretinal membranes, subretinal hemorrhage, and choroidal neovascularization. An entire section is devoted to prevention of complications from macular surgery. All chapters are written by leading experts within the field.
Modern city dwellers are largely detached from the environmental effects of their daily lives. The sources of the water they drink, the food they eat, and the energy they consume are all but invisible, often coming from other continents, and their waste ends up in places beyond their city boundaries. Cities as Sustainable Ecosystems shows how cities and their residents can begin to reintegrate into their bioregional environment, and how cities themselves can be planned with nature’s organizing principles in mind. Taking cues from living systems for sustainability strategies, Newman and Jennings reassess urban design by exploring flows of energy, materials, and information, along with the interactions between human and non-human parts of the system. Drawing on examples from all corners of the world, the authors explore natural patterns and processes that cities can emulate in order to move toward sustainability. Some cities have adopted simple strategies such as harvesting rainwater, greening roofs, and producing renewable energy. Others have created biodiversity parks for endangered species, community gardens that support a connection to their foodshed, and pedestrian-friendly spaces that encourage walking and cycling. A powerful model for urban redevelopment, Cities as Sustainable Ecosystems describes aspects of urban ecosystems from the visioning process to achieving economic security to fostering a sense of place.
Now in a revised and updated Second Edition, this handy guide to eye care uses evidence from the latest clinical trials to deliver practical advice directly applicable to the challenges of daily ophthalmic practice. Helpful illustrations and tables support the text and improve outcomes.
Professor Hay (environmental studies, U. of Tasmania) must have been a patient and long-time follower of environmental debate over the last 35 years to have masterfully untangled the myriad and subtle contentions and changes of heart in ecophilosophy, ecofeminism, ecoreligiosity and spirituality, green critiques of science, green politics, philosophies of place, and ecology's relationship to democracy and postmodernism. Hay's Tasmanian provenance seems less weakness than strength since he provides a more international perspective on environmentalism that includes Australia, North America, and Europe. Not only geographically wide-ranging, Hay is ideologically inclusive, bringing into the environmental forum --without apology or pride--discussions among animal rightists and their critics, and assertions that environmental concern is partially pre-rational. Reading Hay's environmental tome is likely to introduce even seasoned readers to new names (Deborah Slicer, John Rodman, Warwick Fox, Stephen Clark, Ariel Salleh) and so, new arguments. Suitable as a primary or secondary text for an advanced undergraduate or graduate class in environmental thought. Annotation copyrighted by Book News, Inc., Portland, OR
Using both historical and contemporary contexts, The Child Welfare Challenge examines major policy practice and research issues as they jointly shape child welfare practice and its future. This text focuses on families and children whose primary recourse to services has been through publicly funded child welfare agencies, and considers historical areas of service—foster care and adoptions, in-home family-centered services, child-protective services, and residential treatment services—where social work has an important role. This fourth edition features new content on child maltreatment and prevention that is informed by key conceptual frameworks informed by brain science, public health, and other research. This edition uses cross-sector data and more sophisticated predictive and other analytical processes to enhance planning and practice design. The authors have streamlined content on child protective services (CPS) to allow for new chapters on juvenile justice/cross-over youth, and international innovations, as well as more content on biology and brain science. The fourth edition includes a glossary of terms as well as instructor and student resource papers available online.
The availability of electric lighting has changed the lives of people the world over, yet as a major user of electricity it has come under increasing scrutiny in recent years. This scrutiny has focused largely on the environmental consequences, with little consideration of the benefits of lighting. Human Factors in Lighting, Third Edition restores
Schizophrenia: The Positive Perspectivecounters a century-long tradition which has searched relentlessly for the critical deficits and dysfunctions in schizophrenic people. Peter Chadwick, who has himself suffered from the illness, shows that such people can demonstrate elevated creativity, empathy and social sensitivity and are by no means as irrational and misguided as is commonly thought. The author presents the fascinating case studies of some schizophrenics with whom he has worked. Using autobiography, biography, psychometric and experimental methods, he reveals areas of enhanced functioning in those vulnerable to the schizophrenia label, and argues for a much more positive picture of the schizophrenia-prone mind.
Buildings consume 40% of our planet’s materials and 30% of its energy. Their construction uses up to three million tonnes of raw materials a year and generates 20% of the soild waste stream. If we want to survive our urban future, there is no option but to build in ways which improve the health of ecosystems. Understanding the concept of ecological sustainability and translating it into practice as sustainable development is a key challenge for today’s built environment professionals. The skill and vision of those who shape our cities and homes is vital to achieving sustainable solutions to the many environmental, economic and social problems we face on a local, national and global scale. Peter Graham offers here a holistic view of ecologically sustainable building by drawing on established areas of knowledge, demonstrating their relevance to the environmentally-conscious building professional and putting the process, product and impact of building into context. Case studies illustrate how sustainable principles have been applied successfully and discussion topics are offered to stimulate thought. Building Ecology will help planners, surveyors, designers and builders to incorporate sustainability into their everyday practice by: · showing which styles of building are ecologically sustainable · providing fundamental knowledge for making decisions using the principles of ecologically sustainable building · explaining a complex subject in a clear, balanced way. Building Ecology sets out the current scientific view of how nature works and how buildings link with and affect nature. It provides fundamental knowledge for building in harmony with nature and keeping Earth’s life-supporting ecosystems healthy.
The title of this book derives from C. Wright Mills’ classic The Sociological Imagination (Penguin, 1970), in which he sees the essential project of social science as the use of the imagination to 'grasp history and biography and the relations between the two in society'. This enables the social scientist to 'range from the most impersonal and remote transformations to the most intimate features of the human self'. Another of Mills’ concerns was the relationship between 'the personal troubles of the milieu' and 'the public issues of social structure' and these are most acutely illustrated in human genetics, the most personal of the new technologies. The chapters in this volume address these issues through discussions of choice and informed decision-making, risks and hazards, the economic and political organization of new technology, and the public as well as the scientist’s understanding of science. The methods used range from detailed ethnographies, through deconstruction's of text and action, to surveys and interviews.
The use of Bayesian methods for the analysis of data has grown substantially in areas as diverse as applied statistics, psychology, economics and medical science. Bayesian Methods for Categorical Data sets out to demystify modern Bayesian methods, making them accessible to students and researchers alike. Emphasizing the use of statistical computing and applied data analysis, this book provides a comprehensive introduction to Bayesian methods of categorical outcomes. * Reviews recent Bayesian methodology for categorical outcomes (binary, count and multinomial data). * Considers missing data models techniques and non-standard models (ZIP and negative binomial). * Evaluates time series and spatio-temporal models for discrete data. * Features discussion of univariate and multivariate techniques. * Provides a set of downloadable worked examples with documented WinBUGS code, available from an ftp site. The author's previous 2 bestselling titles provided a comprehensive introduction to the theory and application of Bayesian models. Bayesian Models for Categorical Data continues to build upon this foundation by developing their application to categorical, or discrete data - one of the most common types of data available. The author's clear and logical approach makes the book accessible to a wide range of students and practitioners, including those dealing with categorical data in medicine, sociology, psychology and epidemiology.
The idea of human dominion over nature has become entrenched by the dominant rights-based interpretation of private property. Accordingly, nature is not attributed any inherent value and becomes merely the matter of a human property relationship. Earth Jurisprudence: Private Property and the Environment explores how an alternative conception of property might be instead grounded in the ecocentric concept of an Earth community. Recognising that human beings are deeply interconnected with and dependent on nature, this concept is proposed as a standard and measure for human law. This book argues that the anthropocentric institution of private property needs to be reconceived; drawing on international case law, indigenous views of property and the land use practices of agrarian communities, Peter Burdon considers how private property can be reformulated in a way that fosters duties towards nature. Using the theory of earth jurisprudence as a guide, he outlines an alternative ecocentric description of private property as a relationship between and among members of the Earth community. This book will appeal to those researching in law, justice and ecology, as well as anyone pursuing an interest more particularly in earth jurisprudence.
The popularity of bodybuilding is at an all-time high, and the sport is continuing to grow. But seasoned competitors and beginners often have questions about how to look their best on show day. Written by expert bodybuilding coaches Peter Fitschen and Cliff Wilson, Bodybuilding: The Complete Contest Preparation Handbook will guide you through every step of the process to select a competition, prepare for the contest, and make the transition to the off-season. With no other book like it on the market, Bodybuilding offers you scientifically supported and experience-based guidelines to help you have your best show ever. Bodybuilding takes the guesswork out of preparing for a contest and answers common questions such as these: How do I choose the competition and division that are right for me? What mandatory poses do I need to learn for my competition? What is the best workout to do during contest prep? What should I do if I start to spill over during peak week? How long is too long to maintain stage-lean levels of body fat? The authors have created an easily accessible handbook that guides you step by step. The chapters begin with a background of the sport, followed by a discussion of the competitive division options for both men and women. The next chapters will help you through the process of obtaining a stage-ready physique with an evidence-based approach that combines scientific literature with practical experience. These chapters discuss important topics such as nutrition, training, and preparation timing. The next chapters address posing, peak week, tanning, and a number of other topics that will help you bring your most polished physique to the stage. More than 60 full-color photos show body types for each division and each mandatory pose, offering a visual guide to the proper positions for each pose. You will also find information on how to handle the transition to the off-season. With unparalleled detail, Bodybuilding is your go-to guide for bodybuilding success!
7 1. THE LIVER IN NORMAL PREGNANCY 9 Liver palpation. ... 9 Spider angiomas and palmar erythema 9 Histological changes in liver biopsies 10 Liver blood flow ... 10 Hemoglobin and serum iron ... 11 Total leucocyte and differential count. 11 Prothrombin time 11 Urinary bile components 11 Serum bilirubin ... 11 Bromsulfalein retention . 12 Galactose tolerance test . 12 Serum alkaline phosphatase 12 Serum transaminases and other enzymes . 13 Serum cholesterol and serum lipids ... 14 Total serum proteins and serum electrophoresis 14 Serum turbidity and flocculation tests 15 Conclusions ... 15 II. JAUNDICE DURING PREGNANCY ... - - 17 1) Incidence of jaundice durip. g pregnancy 17 2) Classification of jaundice during pregnancy 17 3) Frequency distribution of different diseases causing jaundice during pregnancy ... '. 20 4) Review of literature on jaundice during pregnancy . . 23 Infectious hepatitis during pregnancy ... 23 Susceptability of pregnant women to viral hepatitis 23 Incidence of hepatitis in relation to stage of pregnancy 25 Mortality from hepatitis during pregnancy . 26 Clinical course of hepatitis during pregnancy ... 27 Sequellae from hepatitis during pregnancy ... 28 Child survival from mothers with hepatitis during pregnancy 29 Transplacentar infection with hepatitis virus and incidence of malformation in babies of mothers with hepatitis during pr- nancy. ... 30 Jaundice in liver cirrhosis during plegnancy ... 31 Drug-induced intrahepatic cholestasis during pregnancy ... 32 Obstructive jaundice due to choledocholithiasis during pregnancy 33 Effect of pregnancy in chronic idiopathic hyperbilirubinemias (Dubin-Johnson syndrome, Rotor syndrome, Gilbert-Meul- gracht syndrome) ...
The symposium "Pacific Salmon and Their Ecosystems: Status and Future Options',' and this book resulted from initial efforts in 1992 by Robert J. Naiman and Deanna J. Stouder to examine the problem of declining Pacific salmon (Oncorhynchus spp.). Our primary goal was to determine informational gaps. As we explored different scientific sources, state, provincial, and federal agencies, as well as non-profit and fishing organizations, we found that the information existed but was not being communicated across institutional and organizational boundaries. At this juncture, we decided to create a steering committee and plan a symposium to bring together researchers, managers, and resource users. The steering committee consisted of members from state and federal agencies, non-profit organizations, and private industry (see Acknowledgments for names and affiliations). In February 1993, we met at the University of Washington in Seattle to begin planning the symposium. The steering committee spent the next four months developing the conceptual framework for the symposium and the subsequent book. Our objectives were to accomplish the following: (1) assess changes in anadromous Pacific Northwest salmonid populations, (2) examine factors responsible for those changes, and (3) identify options available to society to restore Pacific salmon in the Northwest. The symposium on Pacific Salmon was held in Seattle, Washington, January 10-12, 1994. Four hundred and thirty-five people listened to oral presentations and examined more than forty posters over two and a half days. We made a deliberate attempt to draw in speakers and attendees from outside the Pacific Northwest.
From the author of How the World Moves: A revelatory new look at the hallowed, diverse, and threatened landscapes of the American Indian For thousands of years , Native Americans have told stories about the powers of revered landscapes and sought spiritual direction at mysterious places in their homelands. In this important book, respected scholar and anthropologist Peter Nabokov writes of a wide range of sacred places in Native America. From the “high country” of California to Tennessee’s Tellico Valley, from the Black Hills of South Dakota to Rainbow Canyon in Arizona, each chapter delves into the relationship between Indian cultures and their environments and describes the myths and legends, practices, and rituals that sustained them.
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
In the modern era, solutions to many environmental problems appear to be beyond the reach of a dialogue based solely on argumentation, dialectics, and the presentation of 'evidence.' The purpose of this study is to construct a bridge between incommensurable ways of perceiving reality, a bridge that can facilitate dialogue across worldview boundaries on environmental issues. This book attempts to link ecology, philosophy, and theology through an exploration of a new model of intercultural dialogue. Case studies provide practical and theoretical applications, which lead to a deeper understanding of not only environmental guardianships but also the fundamental relationship between human beings and nature's being. This book attempts to link ecology, philosophy, and theology through an exploration of a new model of intercultural dialogue. Case studies provide practical and theoretical applications, which lead to a deeper understanding of not only environmental guardianships but also the fundamental relationship between human beings and nature's being.
The International Politics of Whaling examines contemporary whaling issues with an emphasis on three factors: our knowledge of whales and current whale populations and the impact of whaling; the actors and institutions involved in the debate over whaling; and the ethical dimension. Reluctantly, he concludes that the current global moratorium on whaling is problematic and that we must focus instead on habitat preservation in order to protect whales more effectively.
Clinical Reflexology takes the practitioner on a journey of examination, critical review and debate prior to making recommendations for best practice in reflexology. The phenomenal rise in interest by health professionals in Complementary and Alternative Medicine (CAM), and in particular touch therapies, has led to a need for texts that relate and integrate theory and practice to health care settings. Clinical Reflexology does this, expanding and exploring concepts introduced in the first edition. Many CAM books have been written for therapists working in private practice but many of these practitioners are also now working in healthcare settings. This book allows both groups to facilitate the greater integration of clinical reflexology in clinical practice. The book is divided into two sections. The first deals with key themes, including an up-to-date review of the research evidence and appropriate methodology, safe and supported practice and integration issues. All these themes are explored and discussed utilizing the available literature, analysis of models and concepts and are related specifically to health care practice. The second section focuses on the clinical application of reflexology and how it can be best adapted to the context. The contributors are committed pioneers in their field with a track record of integrating reflexology within clinical settings. Many are teachers, coordinators of therapy services and supervisors. ABOUT THE AUTHORS Dr Peter Mackereth is the Clinical Lead for Complementary Therapies and Smoking Cessation Services at The Christie NHS Foundation Trust Manchester. He is a registered nurse, and has worked in intensive care, neurology and oncology. Peter has an MA in Medical Ethics and has completed a PhD project examining reflexology vs. relaxation training for people with Multiple Sclerosis. An author and renowned speaker, Peter has held academic post in number of universities, most recently as Reader in Integrative Health at the University of Derby. Denise Tiran, a midwife, lecturer and reflex zone therapist, is an internationally acclaimed authority on complementary therapies in pregnancy and childbirth. She is Director of Expectancy, the leading provider of professional education on the safe use of complementary therapies in maternity care, including a special pregnancy course for reflexologists. Her latest book, Reflexology for Pregnancy and Childbirth, was published in January 2010.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.
Current, comprehensive, and evidence-based Braunwald's Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area. - Offers balanced, dependable content on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. - Includes 76 new contributing authors and 14 new chapters that cover Artificial intelligence in Cardiovascular Medicine; Wearables; Influenza, Pandemics, COVID-19, and Cardiovascular Disease; Tobacco and Nicotine Products in Cardiovascular Disease; Cardiac Amyloidosis; Impact of the Environment on Cardiovascular Health, and more. - Features a new introductory chapter Cardiovascular Disease: Past, Present, and Future by Eugene Braunwald, MD, offering his unique, visionary approach to the field of cardiology. Dr. Braunwald also curates the extensive, bimonthly online updates that include "Hot Off the Press" (with links to Practice Update) and "Late-Breaking Clinical Trials". - Provides cutting-edge coverage of key topics such as proteomics and metabolomics, TAVR, diabetocardiology, and cardio-oncology. - Contains 1,850 high-quality illustrations, radiographic images, algorithms, and charts, and provides access to 215 videos called out with icons in the print version. - Highlights the latest AHA, ACC, and ESC guidelines to clearly summarize diagnostic criteria and clinical implications. - Provides tightly edited, focused content for quick, dependable reference. Flexible format options include either one or two volumes in print, as well as a searchable eBook with ongoing updates. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Some years ago the Gmelin Institute started to supplement the volumes on halogens and halogen compounds. For the elements chlorine and fluorine these supplementary volumes have already been finished. For the element bromine the volume A 1 is also available. Now the volume B 1 will be published starting with the description of the compounds of bromine. The present volume describes the compounds of bromine with rare gases and with hydrogen. The volume is dominated by the description of HBr and its aqueous solution, hydrobromic acid. Chemical and physical properties of the diatomic molecule HBr are extremely well studied by modern methods. Thus detailed descriptions are given of gas-phase properties, spectra, and properties of condensed phases. Emphasis is laid on elementary reaction processes such as energy transfer and single reaction steps for HBr formation and decomposition. These studies have become classics of modern reaction kinetics. Likewise, elementary reactions of HBr and Br- with nonmetallic compounds are described comprehensively.
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