The 6th edition of this established text is streamlined to a more manageable format, with the Appendices moved to the web-site and a significant shortening of the main text. There is a greater focus on the global analysis of industry and competition; and analysis of the internal environment. In consultation with feedback from their adopters, the authors have concentrated on the fundamentals of strategy analysis and the underlying sources of profit. This reflects waning interest among senior executives in the pursuit of short-term shareholder value. As ever students are provided with the guidance they need to strategic planning, analysis of the health services environment (internal and external) and lessons on implementation; with additional discussionssion of organizational capability, deeper treatment of sustainability and corporate social responsibility and more coverageof the sources of organizational inertia and competency traps. This edition is rich in new examples from real-world health care organizations. Chapters are brought to life by the 'Introductory Incidents', 'Learning Objectives', 'Perspectives', 'Strategy Capsules', useful chapter summaries; and questions for class discussion. All cases and examples have been updated or replaced. In this edition the teaching materials and web supplements have been greatly enhanced, with power-point slides, to give lecturers a unique resource.
2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. - Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. - Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. - Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. - Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. - Access the entire text and illustrations online, fully searchable, at Expert Consult.
Malaria causes more death and disease than any other parasitic pathogen known today. This multiauthored text covers the important areas of malaria research, particularly focusing on those sectors which are of clinical importance for the understanding of the disease, the parasite, and its vector. The chapter authors are all leading experts within their own particular fields. The biology and molecular biology of the parasite, the clinical spectrum of the disease, the pathogenesis of malaria, and the immunology and emergence of malaria vaccines are some examples of the scientific spheres that are discussed. The book is suitable as a text for graduate students and clinicians as well as researchers at universities and companies involved in treating or studying infectious diseases.
Ecological Methods by the late T.R. E. Southwood and revised over the years by P. A. Henderson has developed into a classic reference work for the field biologist. It provides a handbook of ecological methods and analytical techniques pertinent to the study of animals, with an emphasis on non-microscopic animals in both terrestrial and aquatic environments. It remains unique in the breadth of the methods presented and in the depth of the literature cited, stretching right back to the earliest days of ecological research. The universal availability of R as an open source package has radically changed the way ecologists analyse their data. In response, Southwood's classic text has been thoroughly revised to be more relevant and useful to a new generation of ecologists, making the vast resource of R packages more readily available to the wider ecological community. By focusing on the use of R for data analysis, supported by worked examples, the book is now more accessible than previous editions to students requiring support and ideas for their projects. Southwood's Ecological Methods provides a crucial resource for both graduate students and research scientists in applied ecology, wildlife ecology, fisheries, agriculture, conservation biology, and habitat ecology. It will also be useful to the many professional ecologists, wildlife biologists, conservation biologists and practitioners requiring an authoritative overview of ecological methodology.
In Augustine's Leaders, Peter Iver Kaufman works from the premise that appropriations of Augustine endorsing contemporary liberal efforts to mix piety and politics are mistaken--that Augustine was skeptical about the prospects for involving Christianity in meaningful political change. His skepticism raises several questions for historians. What roles did one of the most influential Christian theologians set for religious and political leaders? What expectations did he have for emperors, statesmen, bishops, and pastors? What obstacles did he presume they would face? And what pastoral, polemical, and political challenges shaped Augustine's expectations--and frustrations? Augustine's Leaders answers those questions and underscores the leadership its subject provided as he continued to commend humility and compassion in religious and political cultures that seemed to him to reward, above all, celebrity and self-interest.
Experts in herbicide research and development - chemists and plant physiologists - have written 15 chapters that review all aspects pertinent to Peroxidizing Herbicides, compounds of topical interest since extremely low use rates ensure high environmental safety. This comprehensive review will be welcomed as a unique and timely compilation of the current status of peroxidizing herbicide research and development. It will be of interest to professional chemists and biologists in agrochemical companies, universities and agricultural colleges.
Peter F. Hamilton’s groundbreaking Mandel Files series concludes with The Nano Flower, a tour de force of unbridled imagination and cutting-edge scientific speculation. Greg Mandel is a psychic detective whose skills have been augmented by powerful but dangerous biotechnology. Those abilities have won him success and almost killed him many times over. Little wonder that he has settled down to the life of a gentleman farmer. But Greg’s former employer, the mighty tech company Event Horizon, needs him once more. After Royan, hacker-genius and husband to company owner Julia Evans, mysteriously vanishes, a business rival suddenly boasts an incredible new technology. Has Royan been kidnapped and forced to work for his captors, or is the truth far stranger? The answer may lie in a gift of flowers received by Julia—flowers with DNA like nothing on Earth. Greg already has his hands full with corporate killers and other unsavory characters. Is he going to have to add aliens to the list? The Greg Mandel trilogy—which also includes Mindstar Rising and A Quantum Murder, available in Volume 1—set a new standard for science fiction when it first appeared in the 1990s. The Nano Flower is every bit as gripping today—and even more timely.
Through eight successful editions, and over nearly 40 years, Biogeography: An Ecological and Evolutionary Approach has provided a thorough and comprehensive exploration of the varied scientific disciplines and research that are essential to understanding the subject. The text has been praised for its solid background in historical biogeography and basic biology, that is enhanced and illuminated by discussions of current research. This new edition incorporates the exciting changes of the recent years, and presents a thoughtful exploration of the research and controversies that have transformed our understanding of the biogeography of the world. It also clearly identifies the three quite different arenas of biogeographical research: continental biogeography, island biogeography and marine biogeography. It is the only current textbook with full coverage of marine biogeography. It reveals how the patterns of life that we see today have been created by the two great Engines of the Planet - the Geological Engine, plate tectonics, which alters the conditions of life on the planet, and the Biological Engine, evolution, which responds to these changes by creating new forms and patterns of life.
**ONE OF THE GUARDIAN’S BEST BOOKS OF 2018** Join renowned naturalist Peter Marren on an exciting quest to see every species of wild plant native to Britain. The mysterious Ghost Orchid blooms in near darkness among rotting leaves on the forest floor. It blends into the background to the point of invisibility, yet glows, pale and ghostly. The ultimate grail of flower hunters, it has been spotted only once in the past twenty-five years. Its few flowers have a deathly pallor and are said to smell of over-ripe bananas. Peter Marren has been a devoted flower finder all his life. While the Ghost Orchid offers the toughest challenge of any wild plant, there were fifty more British species Peter had yet to see, having ticked off the first 1,400 rummaging in hedges, slipping down gullies and peering in peat bogs. But he set himself the goal of finding the remaining fifty in a single summer. As it turned out, the wettest summer in years. This expert and emotional journey takes Peter the length and the breadth of the British Isles, from the dripping ancient woods of the New Forest to the storm-lashed cliffs of Sutherland. He paddles in lakes, clambers up cliffs in mist and rain, and walks several hundred miles, but does he manage to find them all? Partly about plants, partly autobiography, Chasing the Ghost is also a reminder that to engage with wild flowers, all we need to do is look around us and enjoy what we see. Praise for Chasing the Ghost: ‘Peter Marren is the unsung hero of Britain’s nature writers’ Stephen Moss, author of Dynasties ‘Jolly, quixotic and ends with real poignancy’ Guardian ‘A poignant reminder to us all to engage with the wild flowers that grow around us’ i Newspaper
European Whales, Dolphins, and Porpoises: Marine Mammal Conservation in Practice presents an intimate view of the workings of international conservation agreements to protect marine mammals, detailing achievements over the last 25 years, identifying weaknesses and making recommendations that governments, scientists, marine stakeholders and the public can take to improve conservation efforts. The book is written by an experienced marine mammal scientist and award-winning conservationist, providing a unique synthesis on their status, distribution and ecology. In addition, it presents information on various conservation threats, including fisheries by catch, contaminants, noise disturbance, plastic ingestion and climate change. This comprehensive resource will appeal to marine mammal conservationists and researchers, as well as environmental and wildlife practitioners at all levels. - Offers an accessible review on how scientists study this challenging group of mammals to gather necessary evidence for conservation action - Illustrates, with striking images, all recorded regional species, including distribution maps, key threats and specific research methods - Includes contributions from leading scientists, conservationists, and members of government and international bodies, like IWC and UNEP
At first no one noticed when the flower was delivered to Julia Evans, owner of Event Horizon, but this flower has genes millions of years in advance of terrestrial DNA. Where did the plant come from? Greg Mandel, telepathic investigator, must find out--before the Nano Flower blooms.
For the first time in a single volume, Peter F. Hamilton’s acclaimed novels—Mindstar Rising and A Quantum Murder—set in a near-future so real it seems ripped from tomorrow’s headlines In Mindstar Rising, Greg Mandel, gifted—or cursed—with biotechnology that makes him a living lie detector, is hired to investigate corporate espionage by Event Horizon, a powerful company about to introduce a technology that will solve the energy problems of a world decimated by global warming. Set two years later, A Quantum Murder once again teams Mandel with Event Horizon and its beautiful young owner, Julia Evans, in a locked-room mystery that combines the ingenuity of an Agatha Christie novel with cutting-edge speculative brilliance. Read together, these novels take on fresh depth and complexity, underscoring the magnitude of Peter F. Hamilton’s creative talent.
Emergency physicians assess and manage a wide variety of problems from patients presenting with a diversity of severities, ranging from mild to severe and life-threatening. They are expected to maintain their competency and expertise in areas where there is rapid knowledge change. Evidence-based Emergency Medicine is the first book of its kind in emergency medicine to tackle the problems practicing physicians encounter in the emergency setting using an evidence-based approach. It summarizes the published evidence available for the diagnosis and treatment of common emergency health care problems in adults. Each chapter contextualizes a topic area using a clinical vignette and generates a series of key clinically important diagnostic and treatment questions. By completing detailed reviews of diagnostic and treatment research, using evidence from systematic reviews, RCTs, and prospective observational studies, the authors provide conclusions and practical recommendations. Focusing primarily on diagnosis in areas where evidence for treatment is well accepted (e.g. DVTs), and treatment in other diseases where diagnosis is not complex (e.g. asthma), this text is written by leading emergency physicians at the forefront of evidence-based medicine. Evidence-based Emergency Medicine is ideal for emergency physicians and trainees, emergency department staff, and family physicians specialising in the acute care of medical and injured patients.
This classic text, whose First Edition one reviewer referred to as"the ecologists' bible," has been substantially revised andrewritten. Not only have the advances made in the field since theSecond Edition been taken into account, but the scope has beenexplicitly extended to all macroscopic animals, with particularattention being paid to fish as well as other vertebrates. Ecological Methods provides a unique synthesis of themethods and techniques available for the study of populations andecosystems. Techniques used to obtain both absolute and relativepopulation estimates are described, and approaches to the directmeasurement of births, deaths, migration and the construction andinterpretation of life tables are reviewed. The text is extensively illustrated, clearly describing a widerange of equipment and methods of analysis. Comprehensive andup-to-date bibliographies to each chapter fully cover the relevantliterature, and references are given to available computer programsand internet addresses. The book has an active web site providingadditional illustrations, details of equipment and programs, andreferences to work published since the revision was completed. Likethe earlier editions, this book will be an indispensable source ofreference to researchers and students at all levels in the fieldsof ecology, entomology and zoology. Completely revised and rewritten edition of a classic. Scope extended to all macroscopic animals, notably fish andother vertebrates. Active web site displaying additional material. References to computer programmes and internet addressesthroughout the text. Affordable paperback.
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Finite element methods have become ever more important to engineers as tools for design and optimization, now even for solving non-linear technological problems. However, several aspects must be considered for finite-element simulations which are specific for non-linear problems: These problems require the knowledge and the understanding of theoretical foundations and their finite-element discretization as well as algorithms for solving the non-linear equations. This book provides the reader with the required knowledge covering the complete field of finite element analyses in solid mechanics. It is written for advanced students in engineering fields but serves also as an introduction into non-linear simulation for the practising engineer.
A soldier of fortune implanted with telepathy glands serves as a bodyguard to the heiress of space factories which someone is trying to sabotage. The setting is a world where people store their personality on a computer for use after death, hoping no one will introduce a virus to kill it.
It is no exaggeration to claim that 46th North Midland Divisions action on 29 September 1918 was the hammer blow that shattered the will of the German High Command.Painting the strategic picture from early 1918 and the dark weeks following the Germans March offensive, the Author lays the ground for the Allied counter-strike. Ahead of them was the mighty Hindenburg Line, the Kaisers formidable defensive obstacle given added strength by the St Quentin Canal.Undaunted the Allies attacked using American, Australian and British formations. Led by Major General Boyd, 46 Division stormed the Canal and, thanks to a combination of sound planning and determined courageous fighting, seized their Hindenburg Line objective by the end of the day.The psychological damage to the German will, already weakened by the failure of the Spring offensive, is demonstrate by Ludendorffs collapse and opening of negotiations that led five weeks later to the Armistice.
The Action Plan for Australian Mammals 2012 is the first review to assess the conservation status of all Australian mammals. It complements The Action Plan for Australian Birds 2010 (Garnett et al. 2011, CSIRO Publishing), and although the number of Australian mammal taxa is marginally fewer than for birds, the proportion of endemic, extinct and threatened mammal taxa is far greater. These authoritative reviews represent an important foundation for understanding the current status, fate and future of the nature of Australia. This book considers all species and subspecies of Australian mammals, including those of external territories and territorial seas. For all the mammal taxa (about 300 species and subspecies) considered Extinct, Threatened, Near Threatened or Data Deficient, the size and trend of their population is presented along with information on geographic range and trend, and relevant biological and ecological data. The book also presents the current conservation status of each taxon under Australian legislation, what additional information is needed for managers, and the required management actions. Recovery plans, where they exist, are evaluated. The voluntary participation of more than 200 mammal experts has ensured that the conservation status and information are as accurate as possible, and allowed considerable unpublished data to be included. All accounts include maps based on the latest data from Australian state and territory agencies, from published scientific literature and other sources. The Action Plan concludes that 29 Australian mammal species have become extinct and 63 species are threatened and require urgent conservation action. However, it also shows that, where guided by sound knowledge, management capability and resourcing, and longer-term commitment, there have been some notable conservation success stories, and the conservation status of some species has greatly improved over the past few decades. The Action Plan for Australian Mammals 2012 makes a major contribution to the conservation of a wonderful legacy that is a significant part of Australia’s heritage. For such a legacy to endure, our society must be more aware of and empathetic with our distinctively Australian environment, and particularly its marvellous mammal fauna; relevant information must be readily accessible; environmental policy and law must be based on sound evidence; those with responsibility for environmental management must be aware of what priority actions they should take; the urgency for action (and consequences of inaction) must be clear; and the opportunity for hope and success must be recognised. It is in this spirit that this account is offered.
Peter Nolan presents a history of psychiatric nursing which contrasts the distress of those who have experienced mental illness with the pioneering efforts of psychiatrists and psychiatric nurses.
This title was first published in 2003. Militant racism is concerned with antagonism and hostility associated with racist activity. Within a society it is expressed by material that may stir up racial hatred and/or discrimination. It can also be seen on the streets and, indeed, the alleged racist criminality orchestrated by militant gangs. After examining the possible causes of militant racism and its effects, this book considers the new laws designed to tackle racially-motivated crime found in the 1998 Crime and Disorder Act. A central theme of the book is the balance between freedom of expression and penalizing racially-offensive expression.
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