After a substantial new essay examining the nature of a properly skeptical historical inquiry into Jesus of Nazareth in the context of contemporary worldviews, from pre-modernism to meta-modernism, Behold the Man presents revised essays on an eclectic range of issues: from how the Epistle of James treats Jesus as Divine within decades of the crucifixion, and an evaluation of recent arguments about the dating of the Fourth Gospel, to debunking claims about Jesus and “ancient aliens,” and furthering debate about the resurrection. With a foreword by eminent New Testament scholar Craig L. Blomberg, and extensive recommended resources, Behold the Man: Essays on the Historical Jesus represents a wide-ranging, interdisciplinary engagement with historical Jesus studies.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
This volume contains papers addressing issues in task-based research into second language learning which are essential to informed pedagogic decision-making about how best to achieve this aim. These issues include research into the design characteristics of pedagogic tasks that promote the accuracy, fluency and complexity of learner language; the role of individual differences in the motivational and other cognitive variables that demands made by pedagogic tasks draw on; the extent to which tasks, and teacher interventions during task performance, promote the quantity and quality of interaction that facilitate L2 learning; and the generalizability of task-based research in laboratory contexts to classroom settings.
Introduction to temperate floodplains -- Hydrology -- Floodplain and geomorphology -- Biogeochemistry -- Ecology: introduction -- Floodplain forests -- Primary and secondary production -- Fish and other vertebrates -- Ecosystem services and floodplain reconciliation -- Floodplains as green infrastructure -- Case studies of floodplain management and reconciliation -- Central Valley floodplains: introduction and history -- Central Valley floodplains today -- Reconciling Central Valley floodplains -- Conclusions: managing temperate floodplains for multiple benefits
This second edition of what was in 1999 an acclaimed work, has been completely rewritten. In approaching this, the authors have considerably increased the analysis of the theoretical aspects of criminal law and strengthened citations of academic literature and comparative case law while keeping the narrative concise and focused for easy use by practitioners. Key benefits to readers include a complete overview of criminal law theory; a new series of chapters on the law of evidence as it applies in the fraught circumstances of a criminal trial; a much more analytical approach to the general part and to criminal defences; and the comprehensive coverage of all the major, and many minor, areas of indictable crime. Since the last edition, commentary and case law on sexual offences has proliferated as have legislative interventions; a completely new scheme for dealing with property offences was necessitated by a series of recent statutes; company law and competition offences have assumed a greater significance; and the range of offences covered has had to be increased in order to ensure a comprehensive coverage of this most sensitive and politically charged aspect of law.
This study considers diverse features of syntax and translation technique in the Syriac version of 1 Kings. It seeks to formulate rules and make observations about translation tendencies that may be generalized to some extent across the whole Peshitta.
Good Faith and Insurance Contracts sets out an exhaustive analysis of the law concerning the duty of utmost good faith, as applied to insurance contracts. Now in its fourth edition, it has been updated to address the arrival of the Insurance Act 2015, as well as any references to new case law. In addition, it synthesises all known judicial decisions by the English Courts concerning good faith in this area. This book is still the only text devoted to a discussion of the duty of utmost good faith applicable to insurance contracts. As good faith is an issue which arises in respect of all insurance contracts, it is a book which will be extremely useful to lawyers involved in insurance as well as insurance practitioners.
This book is an introduction to the archaeology of Australia from prehistoric times to the eighteenth century AD. It is the only up-to-date textbook on the subject and is designed for undergraduate courses, based on the author's considerable experience of teaching at the Australian National University. Lucidly written, it shows the diversity and colourfulness of the history of humanity in the southern continent. The Archaeology of Ancient Australia demonstrates with an array of illustrations and clear descriptions of key archaeological evidence from Australia a thorough evaluation of Australian prehistory. Readers are shown how this human past can be reconstructed from archaeological evidence, supplemented by information from genetics, environmental sciences, anthropology, and history. The result is a challenging view about how varied human life in the ancient past has been.
Researching Pedagogic Tasks brings together a series of empirical studies into the use of pedagogical tasks for second language learning, with a view to better understanding the structure of tasks, their impact on students, and their use by teachers. The volume starts with an introduction to the background and key issues in the topic area and is then organised into three sections: the first section focuses on the language and learning of students on tasks the second on the use of tasks in the language classroom the third on the use of tasks for language testing Each section begins with a succinct section introduction, and the volume concludes with an afterword relating the theme of the volume to issues in curriculum development. The chapters include both experimental and qualitative approaches to the topic, some providing original accounts of specific studies, others offering overviews of linked series of studies.
This work covers two bases, both performance optimization strategies and a complete introduction to mathematical procedures required for a successful circuit design. It starts from the basics of mathematical procedures and circuit analysis before moving on to the more advanced topics of system optimization and synthesis, along with the complete mathematical apparatus required. The authors have been at pains to make the material accessible by limiting the mathematics to the necessary minimum.
Are natural resources really so limited that, as Mahatma Gandhi once famously said, “Earth provides enough to satisfy every man’s need, but not every man’s greed”? (TE 2012) This limiting view of natural resources can be contrasted with an opposing view by John Maynard Keynes, who “summarized Say’s Law as ‘supply creates its own demand’” but then “turned Say’s Law on its head in the 1930s by declaring that demand creates its own supply,” so whenever a demand exists, there will be resources to create the supply. (EN 2012) Contrary to these opposing views (and other ones as will be discussed in the book), natural resources, in relation to both diversity and discontinuity are neither possible or impossible, nor desirable or undesirable to the extent that the respective ideologues on different sides would like us to believe. Needless to say, this challenge to the opposing views of natural resources does not mean that natural resources are unimportant, or that those interdisciplinary fields (related to natural resources) like conservation biology, environmental management, ecological economics, political ecology, environmental ethics, adaptive management, genetic engineering, Malthusianism, and so on are not worth studying. Of course, neither of these extreme views is reasonable. Rather, this book offers an alternative, better way to understand the future of natural resources, especially in the dialectic context of diversity and discontinuity—while learning from different approaches in the literature but without favoring any one of them or integrating them, since they are not necessarily compatible with each other. More specifically, this book offers a new theory (that is, the resilient theory of natural resources) to go beyond the existing approaches in a novel way. If successful, this seminal project is to fundamentally change the way that we think about natural resources in relation to diversity and discontinuity from the combined perspectives of the mind, nature, society, and culture, with enormous implications for the human future and what the author originally called its “post-human” fate.
This collection of original chapters brings together cutting-edge research on informal education - that is, learning practices that emphasise dialogue and learning through everyday life. For the first time, it highlights the way in which geography matters to informal education practices. Through a range of examples from the nineteenth, twentieth and twenty-first centuries, and from a range of geographical contexts, the authors explore the relationship between history, geography and practice in the field of informal education. Case studies include youth work, Scouting, Guiding, Care Farms, youth music programmes and the use of online/information technologies. This book will be of interest to geographers and sociologists of education, childhood and youth scholars. It also provides an engaging resource and collection of case studies for educators, youth workers and other professionals who work with young people.
This companion provides a collection of frequently needed numerical data as a convenient desk-top or pocket reference for atmospheric scientists as well as a concise source of information for others interested in this matter. The material contained in this book was extracted from the recent and the past scientific literature; it covers essentially all aspects of atmospheric chemistry. The data are presented primarily in the form of annotated tables while any explanatory text is kept to a minimum. In this condensed form of presentation, the volume may serve also as a supplement to many textbooks used in teaching the subject at various universities. Peter Warneck, a physical chemist specializing in atmospheric chemistry, received the diploma in 1954 and the doctorate in 1956 at the university in Bonn, Germany. In 1959, following several postdoctoral assignments, he joined the GCA Corporation in Bedford, Massachusetts, where he explored elementary processes in the atmospheres of the earth and other planets. He returned to Germany in 1970 to head the chemical kinetics group in the Air Chemistry Division of the Max-Planck-Institute for Chemistry in Mainz. In 1974 he also became professor of physical chemistry at the university in Mainz. In 1991, following German reunification, Warneck was appointed the founding director of the new Institute for Tropospheric Research in Leipzig. He served in this position parallel to his activities in Mainz until official retirement. Warneck’s research included laboratory studies of chemical mechanisms and photochemistry as well as the development of analytical techniques for field measurements. Since 1990, his interests are focused on chemical reactions in clouds. Jonathan Williams is an atmospheric chemist. He received his BSc in Chemistry and French and his Ph.D. in Environmental Science from the University of East Anglia, England. Between 1995-1997 he worked as a postdoctoral researcher at the NOAA Aeronomy laboratory in Boulder, USA, and from 1998 to present as a member of staff at the Max Planck Institute for Chemistry, Mainz, Germany. He has participated in many international field measurement campaigns on aircraft, ships and at ground stations. Dr Williams is currently an editor on three atmospheric chemistry journals. His present research involves investigating the chemistry of reactive organic species in the atmosphere, in particular over forested ecosystems and in the marine boundary layer. Dr Williams leads a research group focussed specifically on Volatile Organic Compounds (VOC) at the Max Planck Institute and in 2008 he was made an honorary Reader at the University of East Anglia, UK.
This book is all about improving the health care of elderly people, which is facing unprecedented challenges in the 1990s. Energies need to be concentrated in three main areas: • the development of high quality care in community settings • the future role of specialized hospital services • the way that long-term care is delivered. All of these are interconnected and success with any of them depends on successful relationships. For example, success in community care requires working interfaces with primary care, the private sector and hospital care. These interfaces are not static but comprise dynamic interactions between people - people in different teams, with different back grounds, training, perspectives and interests. What people do is influenced strongly by the organizations they work for. These inescapable facts lead us to the structure of this book. By concentrating on sectors, people and organizations, we hope to deal with all the important relationships in a coherent way. Yet this book is not intended to be from a service providers' perspective. We have arranged the book in this way so that providers are best equipped to meet the needs of their customers - whether they are patients, resi dents or clients. We know that elderly people may experience dislocation in their care because of frictions and gaps be tween different sectors, disciplines, teams and organizations. To achieve seamless care, there is a need for greater under standing and harmony of purpose and action across the care spectrum.
Kingdom through Covenant is a careful exposition of how the biblical covenants unfold and relate to one another—a widely debated topic, critical for understanding the narrative plot structure of the whole Bible. By incorporating the latest available research from the ancient Near East and examining implications of their work for Christology, ecclesiology, eschatology, and hermeneutics, scholars Peter J. Gentry and Stephen J. Wellum present a thoughtful and viable alternative to both covenant theology and dispensationalism. This second edition features updated and revised content, clarifying key material and integrating the latest findings into the discussion.
An indispensable reference for any practicing synthetic organic or medicinal chemist, this book continues the tradition of Greene’s as comprehensive in the overall scope of coverage, providing the most relevant and useful examples to illustrate each methodology. • Presents valuable material, on the application of protective groups in organic chemistry, that is not easily found by casual searching • Helps chemists to plan, investigate, and carry out organic syntheses in an efficient manner • Adds over 2800 new references to update since the publication of the last edition • Reviews of the prior edition: "An essential bible for the library or personal bookshelf of chemists performing complex synthesis." (CHOICE, May 2007) "...the most up-to-date compilation available...should be an integral part of all institutional libraries...it is also highly recommended that individuals...maintain their own copy..." (Journal of Medicinal Chemistry, March 8, 2007) "...continues to be a comprehensive guide to the techniques for the formation and cleavage of protective groups." (Journal of the American Chemical Society, January 31, 2007)
First published in 1992. The collapse of communist rule in Eastern Europe has led to a widespread view that socialism is a dead, or at least dying, force. Labour’s Utopias argues that this assumption is based on the popular conception that socialism’s various traditions are simply different means to a common end. The author looks at three strands of socialism – Bolshevism, Fabianism and German Social Democracy – in order to assess whether this argument is justified, concluding that in fact each has a distinct vision of an ideal future. This study will appeal to scholars and students of politics, history and socialism, and to all those with an interest in the alternatives to capitalism.
Revised and updated, this edition covers general principles of overdose management; the automonic nervous system, neurotransmitters and drugs; drugs used in psychiatry; cardiac drugs; agents that burn; gases and abnormal haemoglobin formation; the
The authors emphasize a methodological approach in the analysis of the health impact, circumstances, and costs of injuries. They detail the role of health services in injury prevention and describe surveillance methods and effective preventive measures that can be implemented relatively easily, even in countries with limited resources.
Carbon analogs of carbohydrates, dubbed C-glycosides, have remained an important and interesting class of mimetics, be it in natural product synthesis, for pharmacological applications, as conformational probes, or for biological studies. C-Furanosides: Synthesis and Stereochemistry provides a much-needed overview of synthetic and stereochemical principles for C-furanosides: analogs of a 5-membered ring carbohydrate glycoside (furanoside), in which the anomeric oxygen has been replaced with a carbon. While our understanding of conformational behavior and of stereoselective synthesis in 6-membered ring compounds is quite good, our ability to predict the conformation of 5-membered ring compounds, or to predict the stereochemical outcome of a given reaction, remains anecdotal. Through a comprehensive review of literature approaches to the different C-furanoside stereoisomers, as well as an interpretation of the outcome in terms of a reasonable number of stereochemical models, C-Furanosides: Synthesis and Stereochemistry enables the reader to determine the best approach to a particular C-glycoside compound, and also hopes to provide a certain level of rationalization and predictability for the synthesis of new systems. - Provides a comprehensive review of the growing literature in C-furanosides - Enables readers to choose the most convenient approach to access a defined target in natural products synthesis or pharmacology and make reasonable predictions for the stereochemical outcome in unpublished cases - Explores the various rational models for stereochemical analysis of furanoside reactivity, with a clear distinction made between physical chemical mechanisms and stereochemical models
Long recognized as an essential reference for therapists and surgeons treating the hand and the upper extremity, Rehabilitation of the Hand and Upper Extremity helps you return your patients to optimal function of the hand, wrist, elbow, arm, and shoulder. Leading hand surgeons and hand therapists detail the pathophysiology, diagnosis, and management of virtually any disorder you're likely to see, with a focus on evidence-based and efficient patient care. Extensively referenced and abundantly illustrated, the 7th Edition of this reference is a "must read" for surgeons interested in the upper extremity, hand therapists from physical therapy or occupational therapy backgrounds, anyone preparing for the CHT examination, and all hand therapy clinics. - Offers comprehensive coverage of all aspects of hand and upper extremity disorders, forming a complete picture for all members of the hand team—surgeons and therapists alike. - Provides multidisciplinary, global guidance from a Who's Who list of hand surgery and hand therapy editors and contributors. - Includes many features new to this edition: considerations for pediatric therapy; a surgical management focus on the most commonly used techniques; new timing of therapeutic interventions relative to healing characteristics; and in-print references wherever possible. - Features more than a dozen new chapters covering Platelet-Rich Protein Injections, Restoration of Function After Adult Brachial Plexus Injury, Acute Management of Upper Extremity Amputation, Medical Management for Pain, Proprioception in Hand Rehabilitation, Graded Motor Imagery, and more. - Provides access to an extensive video library that covers common nerve injuries, hand and upper extremity transplantation, surgical and therapy management, and much more. - Helps you keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management—all clearly depicted with full-color illustrations and photographs.
Agricultural Waste Diversity and Sustainability Issues: Sub Saharan Africa as Case Study presents solutions for overcoming limitations, guiding developmental processes, and improving knowledge transfer in agricultural waste management and development. The book gives considerable attention to treatment and conversion, with best management practices involving the reduction and elimination of waste volume in its various forms, sectors and streams. Sections cover waste management in the agriculture and food sector, including methodological approaches in waste preparation and processes, the most important energy generation techniques and strategies, and best practices, management, sustainability, associated technologies, accountability, communications, and involvement surrounding diverse stakeholders. Agricultural Waste Diversity and Sustainability Issues: Sub Saharan Africa as Case Study illustrates the use of mathematical models to minimize operational cost in agro-waste management processes and discusses the application of eco-efficiency. Ultimately, the book focuses on the prospect of agro-wastes management and risk associated in the sub-Saharan African region, including Nigeria, Uganda, and South Africa as case studies. - Captures a solutions-based assessment that redresses the challenges created by a poor biodiversity strategy in Sub-Saharan Africa to meet present needs in SSA and around the world - Provides foundational information for agricultural diversity, food waste elimination, clean energy production, and technology emergence - Enables a greater understanding of the state-of-the-art approach for effective biodegradable waste management - Inspires further research into sustainable and cost-effective biowaste operations, wastes management models, methodologies for utilization and nascent technologies that are capable of bolstering clean energy generation
Portraying themselves as challenging blind religious dogma with evidence-led skepticism, the neo-atheist movement claims that the New Testament contains unreliable tales about a mythical figure who, far from being the resurrected Lord of life, may not even have lived. This comprehensive critique documents the falsehood of these neo-atheist claims, correcting their historical and philosophical mistakes to show how we can get at the truth about the historical Jesus.
The standard reference in the field, this acclaimed work synthesizes findings from hundreds of carefully selected studies of mental health treatments for children and adolescents. Chapters on frequently encountered clinical problems systematically review the available data, identify gaps in what is known, and spell out recommendations for evidence-based practice. The authors draw on extensive clinical experience as well as research expertise. Showcasing the most effective psychosocial and pharmacological interventions for young patients, they also address challenges in translating research into real-world clinical practice. New to This Edition *Incorporates over a decade of research advances and evolving models of evidence-based care. *New chapter topic: child maltreatment. *Separate chapters on self-injurious behavior, eating disorders, and substance use disorders (previously covered in a single chapter on self-harming disorders). *Expanded chapters on depression, anxiety, and conduct disorder. *Includes reviews of the burgeoning range of manualized psychosocial "treatment packages" for children.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today's new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia the Americas.Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard.Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice.
Unequalled in scope, depth, and clinical precision, Retina, 5th Edition keeps you at the forefront of today’s new technologies, surgical approaches, and diagnostic and therapeutic options for retinal diseases and disorders. Comprehensively updated to reflect everything you need to know regarding retinal diagnosis, treatment, development, structure, function, and pathophysiology, this monumental ophthalmology reference work equips you with expert answers to virtually any question you may face in practice. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Examine and evaluate the newest diagnostic technologies and approaches that are changing the management of retinal disease, including future technologies which will soon become the standard. Put the very latest scientific and genetic discoveries, diagnostic imaging methods, drug therapies, treatment recommendations, and surgical techniques to work in your practice. Benefit from the extensive knowledge and experience of esteemed editor Dr. Stephen Ryan, five expert co-editors, and a truly global perspective from 358 other world authorities across Europe, Asia, Australasia, and the Americas. Make the best use of new technologies with expanded and updated coverage of optical coherence tomography (OCT), fundus imaging, and autofluorescence imaging. Apply the latest knowledge on anti-VEGF therapy for age related macular degeneration, diabetic retinopathy and vein disease. Learn about artificial vision, drug delivery to the posterior segment, advances in macular surgery, vitrectomy, and complex retinal detachment, with updates on tumors, retinal genetics, cell biology, important basic science topics, and much more. Get the most out of new pharmacologic approaches in the management of age-related macular degeneration and diabetic retinopathy. In your practice, diagnostic evaluations, and now even treatments, will be influenced by recent scientific discoveries such as in the areas of nanotechnology, neuro protection, stem cells and gene therapy, among other scientific contributions. View videos of surgical procedures and access the complete contents of Retina, 5th Edition online at www.expertconsult.com, fully searchable, with regular updates and a downloadable image gallery.
Considered by many historians to be the birthplace of the Confederacy, South Carolina experienced one of the longest and most turbulent Reconstruction periods of all the southern states. After the Civil War, white supremacist leadership in the state fiercely resisted the efforts of freed slaves to secure full citizenship rights and to remake society based upon an expansive vision of freedom forged in slavery and the crucible of war. Despite numerous obstacles, African Americans achieved remarkable social and political advances in the ten years following the war, including the establishment of the state's first publicly-funded school system and health care for the poor. Through their efforts, the state's political process and social fabric became more democratic. Peter F. Lau traces the civil rights movement in South Carolina from Reconstruction through the early twenty-first century. He stresses that the movement was shaped by local, national, and international circumstances in which individuals worked to redefine and expand the meaning and practice of democracy beyond the borders of their own state. Contrary to recent scholars who separate civil rights claims from general calls for economic justice, Lau asserts that African American demands for civil rights have been inseparable from broader demands for a redistribution of social and economic power. Using the tension between rights possession and rights application as his organizing theme, Lau fundamentally revises our understanding of the civil rights movement in America. In addition to considering South Carolina's pivotal role in the national civil rights movement, Lau offers a comprehensive analysis of the National Association for the Advancement of Colored People (NAACP) during the height of its power and influence, from 1910 through the years following Brown v. Board of Education (1954). During this time, the NAACP worked to ensure the rights guaranteed to African Americans by the 14th and 15th amendments and facilitated the emergence of a broad-based movement that included many of the nation's rural and most marginalized people. By examining events that occurred in South Carolina and the impact of the activities of the NAACP, Democracy Rising upends traditional interpretations of the civil rights movement in America. In their place, Lau offers an innovative way to understand the struggle for black equality by tracing the movement of people, institutions, and ideas across boundaries of region, nation, and identity. Ultimately, the book illustrates how conflicts caused by the state's history of racial exclusion and discrimination continue to shape modern society.
Stay up to date on today's most common GI and liver disorders and their management with GI/Liver Secrets Plus. This enhanced medical reference book is an excellent resource for understanding the physiology and therapy in hepatic and digestive disease. Whether preparing for an exam or quickly checking a clinical question, the user-friendly Secrets Series® style makes this book a valuable addition to your library! - Easily locate important information with bulleted lists, tables, boxes, short answers, and a highly detailed index to expedite reference. - Access a broad range of topics that focus on all of today's most common GI and liver disorders and their management.
Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
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