The CRC Handbook of Chromatography is a series of work-bench references for scientists and researchers using chromatographic systems for the analysis of organic and inorganic compounds. This handbook is an assemblage of tables where, besides data obtained by modern separation methods, older sources often difficult to access have been included to give maximum information. For use in scientific research and routine analysis where the exact determination of plant pigments, because of their light absorbing properties and defined tasks, is necessary.
This new edition of Sky Pilot is beautifully reformatted and republished, for a new reading audience. It is a comprehensive update of the 1st edition that was published in 1990 by the same author. Sky Pilots is timely. In an era when the importance of Chaplaincy is not fully understood in some quarters, the need for it is real and remains undiminished. These stories will showcase to the general reader that our Air Force Padres do so much more than conduct religious services. The author, Peter Davidson, in this well researched work, has captured much of the breadth of the amazing work the Chaplains of the Royal Australian Air Force give in the line of duty. It is a history of the work of God who calls them to care for all people at a time in the history of the world where, now probably more than ever, we might listen for a fresh Voice of the One who has been with us always, who is with us now, and who will continue with us as we step forward into an uncertain future.,
First published in 2009. From the founding of Jamestown to the American Civil War, slavery and abolition shaped American national, regional and racial identities. This four-volume reset edition draws together rare sources relating to American slavery systems. Volume 3 includes the Antebellum Period from 1828 to 1859.
This book reproduces and expands upon the author’s mother’s diary that she kept from 1942 through 1945 while she lived in England. For most of that time she resided in eastern Surrey about 20 miles from the southern outskirts of London. As part of ‘Bomb Alley’ her area of the county experienced air raids as well as V1 and V2 attacks. She was a war bride, having been married in 1940 to a Canadian army officer who served on the staff of the 1st Canadian Army in England, France and Holland. The author has extensively annotated the diary entries and added considerable historical background in relation to both domestic and military matters. The book describes in detail what life was like for a woman starting a family and keeping house in the English countryside during World War 2, and how different were lifestyles then from what they are today. In revisiting the circumstances surrounding his and his sister’s birth, the journey for the author was one of personal revelation as well as historical interest.
How does a religious fundamentalist come to embrace a counter-cultural world view? Fundamentalism can be analysed from a variety of perspectives. It is a type of belief system which enables individuals to make sense of their lives and provides them with an identity. It is a social phenomenon, in which strictly religious people act according to the norms, values, and beliefs of the group to which they belong. It is a cultural product, in the sense that different cultural settings result in different forms of fundamentalism. And it is a global phenomenon, in the obvious sense that it is to be found everywhere, and also because it is both a reaction against, and also a part of, the globalising modern world. Religious Fundamentalism deals with all of these four levels of analysis, uniquely combining sociological and psychological perspectives, and relating them to each other. Each chapter is followed by a lengthy case study, and these range from a close textual analysis of George W. Bush’s second inaugural speech through to a treatment of Al-Qaida as a global media event. This book provides a comprehensive social scientific perspective on a subject of immense contemporary significance, and should be of use both to university students and also to students of the contemporary world.
This book introduces and analyzes the crucial role of AP-1 in cell growth, proliferation, differentiation, and apoptosis. AP-1 is the endpoint of several pathways of signal transduction, including one that triggers cancerous growth. The control of its activity is an issue of basic science, cancer therapy, and other diseases. The chapters provide multiple viewpoints of the emerging data on AP-1, including its role as a factor regulating genes involved in the metastatic properties of cancer, as a factor that interacts with viral gene products, and as a part of the mechanism by which steroid and retinoic acid receptors function as anti-inflammatory proteins.
First published in 1989, the main thrust in this volume has been to denote and elucidate a source of information on motorcyclists・a source which the editors believe is particularly rich with data about characteristics, images and everyday social behaviors.
There are moments in American history when all eyes are focused on a federal court: when its bench speaks for millions of Americans, and when its decision changes the course of history. More often, the story of the federal judiciary is simply a tale of hard work: of finding order in the chaotic system of state and federal law, local custom, and contentious lawyering. The Federal Courts is a story of all of these courts and the judges and justices who served on them, of the case law they made, and of the acts of Congress and the administrative organs that shaped the courts. But, even more importantly, this is a story of the courts' development and their vital part in America's history. Peter Charles Hoffer, Williamjames Hull Hoffer, and N. E. H. Hull's retelling of that history is framed the three key features that shape the federal courts' narrative: the separation of powers; the federal system, in which both the national and state governments are sovereign; and the widest circle: the democratic-republican framework of American self-government. The federal judiciary is not elective and its principal judges serve during good behavior rather than at the pleasure of Congress, the President, or the electorate. But the independence that lifetime tenure theoretically confers did not and does not isolate the judiciary from political currents, partisan quarrels, and public opinion. Many vital political issues came to the federal courts, and the courts' decisions in turn shaped American politics. The federal courts, while the least democratic branch in theory, have proved in some ways and at various times to be the most democratic: open to ordinary people seeking redress, for example. Litigation in the federal courts reflects the changing aspirations and values of America's many peoples. The Federal Courts is an essential account of the branch that provides what Massachusetts Supreme Judicial Court Judge Oliver Wendell Homes Jr. called "a magic mirror, wherein we see reflected our own lives.
Actins are a highly conserved family of proteins found in virtually all eukaryotic cells. They have prolific roles in cell motility - from the contraction of striated muscle to the movement of organelles within cells, and are known to interact with a diverse number of proteins families from myosins to gelsolins. This up-to-date edition gives a comprehensive account of actin sequence, mutation and structure as well as providing insight into ligand-binding sites and drug and toxin binding. Illustrated throughout, this modern text also contains an extensive bibliography for the interested reader.
This power, by necessity and preference, has become the central congressional tool for participating in national security policy. Inevitably attacks on policy are transformed into attacks on the making and effects of appropriations.
The Fourth Edition of Greene's Protective Groups in Organic Synthesis continues to be an indispensable reference for controlling the reactivity of the most common functional groups during a synthetic sequence. This new edition incorporates the significant developments in the field since publication of the third edition in 1998, including... New protective groups such as the fluorous family and the uniquely removable 2-methoxybenzenesulfonyl group for the protection of amines New techniques for the formation and cleavage of existing protective groups, with examples to illustrate each new technique Expanded coverage of the unexpected side reactions that occur with protective groups New chart covering the selective deprotection of silyl ethers 3,100 new references from the professional literature The content is organized around the functional group to be protected, and ranges from the simplest to the most complex and highly specialized protective groups.
Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations Endocrine disrupters are chemicals both man-made and natural that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals. Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including: Crustaceans and mollusks Insects Fish Amphibians and reptiles Birds and mammals Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost. Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field. Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.
With the combined expertise of leading hand surgeons and therapists, Rehabilitation of the Hand and Upper Extremity, 6th Edition, by Drs. Skirven, Osterman, Fedorczyk and Amadio, helps you apply the best practices in the rehabilitation of hand, wrist, elbow, arm and shoulder problems, so you can help your patients achieve the highest level of function possible. This popular, unparalleled text has been updated with 30 new chapters that include the latest information on arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management. An expanded editorial team and an even more geographically diverse set of contributors provide you with a fresh, authoritative, and truly global perspective while new full-color images and photos provide unmatched visual guidance. Access the complete contents online at www.expertconsult.com along with streaming video of surgical and rehabilitation techniques, links to Pub Med, and more. Provide the best patient care and optimal outcomes with trusted guidance from this multidisciplinary, comprehensive resource covering the entire upper extremity, now with increased coverage of wrist and elbow problems. Apply the latest treatments, rehabilitation protocols, and expertise of leading surgeons and therapists to help your patients regain maximum movement after traumatic injuries or to improve limited functionality caused by chronic or acquired conditions. Effectively implement the newest techniques detailed in new and updated chapters on a variety of sports-specific and other acquired injuries, and chronic disorders. Keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management See conditions and treatments as they appear in practice thanks to detailed, full-color design, illustrations, and photographs. Access the full contents online with streaming video of surgical and rehabilitation techniques, downloadable patient handouts, links to Pub Med, and regular updates at www.expertconsult.com. Get a fresh perspective from seven new section editors, as well as an even more geographically diverse set of contributors.
The aim of this book is to give a simple, short, and elementary introduction to the second quantized formalism as applied to a many-electron system. It is intended for those, mainly chemists, who are familiar with traditional quantum chemistry but have not yet become acquainted with second quantization. The treatment is, in part, based on a series of seminars held by the author on the subject. It has been realized that many quantum chemists either interested in theory or in applications, being educated as chemi~ts and not as physicists, have never devoted themselves to taking a course on the second quantized approach. Most available textbooks on this topic are not very easy to follow for those who are not trained in theory, or they are not detailed enough to offer a comprehensive treatment. At the same time there are several papers in quantum chemical literature which take advantage of using second quantization, and it would be worthwhile if those papers were accessible for a wider reading public. For this reason, it is intended in this survey to review the basic formalism of second quantization, and to treat some selected chapters of quantum chemistry in this language. Most derivations will be carried out in a detailed manner, so the reader need not accept gaps to understand the result.
Intended for cell biologists, biophysicists, biochemists, molecular biologists, physiologists, researchers in hemostatsis and thrombosis and pathologists, this book provides an insight into cell adhesion from three interdisciplinary perspectives: fundamental facts of adhesion; molecular biochemistry of adhesion and physiological aspects. It summarizes the basic aspects of surfaces in general and describes the theoretical and experimental tools necessary to investigate cell adhesion, including the basic biochemistry and molecular biology of adhesion. The book offers concise treatment of individual topics, features current material, and provides key references as a guide to further study.
Developed by UK and US anesthetists with extensive experience in theater, this book describes the latest anesthesia techniques, practices, and equipment used in current combat and humanitarian operations. Includes chapters on topics such as injuries and physiology, team members, protocols, vascular access, airway management, burns, imaging, pain management and medications, regional anesthesia, ventilation, and postoperative management.
Rarely have the many mechanisms that might underlie neural plasticity been examined as explicitly as they are in this broad, lavishly illustrated treatment of plasticity in the somatosensory system. The reader is provided with state-of-the-art knowledge of connections at all levels of the somatosensory system. The authors examine the propensity for changes of connectivity in both the mature and developing mammal and make clear proposals regarding the mechanisms underlying these changes. Their functional significance to relevant psychophysical and neurological observations is also discussed.
This title includes the following features: Great breadth of coverage inone volume: covers all aspects of cancer, in a concise and affordable format;Provides a comprehensive introduction to the initiation, development, andtreatment of cancer; Chapter are written by experts in each field, giving astate-of-the-art summary of each topic; Extensive references provide links toall the relevant literature, facilitating further study
This book describes the experiences of the author's great-uncle, Wilberforce Cooper, who was an Anglican priest ministering to the people of Vancouver's downtown east side during 1921-1952. Reverend Cooper began his ecclesiastical calling in the slums of London and then as a British Army chaplain in the hospitals and trenches of WW1 before moving to Canada - first to the B.C. Cariboo and then to be the rector of St. James Church in Vancouver. During the early-mid 1900s the East End of Vancouver was home to most of the city's poor, homeless, addicted and unemployed, and was a magnet for illegal intoxicants, disreputable venues and prostitution. In addition, the East End was where Chinese and Japanese immigrants had settled and their presence attracted the continuing attention of white racists. And all this vice and prejudice was enabled by a corrupt Civic Administration that depended upon graft. This was the parish that Father Cooper presided over and where he became well known and loved as someone who cared and fought for the physical as well as the spiritual wellbeing of each individual resident. The author has made use of unpublished memoirs as well as stories in newspapers and other writings to document his great-uncle's life and times. While a number of references to Rev. Cooper's religious thought and outreach can be found in the literature, this is the first book to address his work and actions solidly within the context of the social and political milieu of the Lower Mainland during his tenure.
Spencer Bower: Reliance-Based Estoppel, previously titled Estoppel by Representation, is the highly regarded and long established textbook on the doctrines of reliance-based estoppel, by which a party is prevented from changing his position if he has induced another to rely on it such that the other will suffer by that change. Since the fourth edition in 2003 the House of Lords has decided two proprietary estoppel cases, Cobbe v Yeoman's Row Property Management Ltd and Thorner v Major, whose combined effect is identified as helping to define a criterion for a reliance-based estoppel founded on a representation, namely that the party estopped actually intends the estoppel raiser to act in reliance on the representation, or is reasonably understood to intend him so to act. Other developments in the doctrine of proprietary estoppel have required a complete revision of the related chapter, Chapter 12, in this edition. Thorner v Major confirms too the submission in the fourth edition that unequivocality is a requirement for any reliance-based estoppel founded on a representation. Other views expressed in the fourth edition are also noted to have been upheld, such as the recognition that an estoppel may be founded on a representation of law (Briggs v Gleeds), that a party may preclude itself from denying a proposition by contract as well as another's reliance (Peekay Intermark Ltd v Australia and New Zealand Banking Group Ltd and Springwell Navigation Corp v JP Morgan Chase Bank) and that an estoppel by deed binds by agreement or declaration under seal rather than by reason of reliance (Prime Sight Ltd v Lavarello). With the adjustment reflected in the change of title, and distinguishing the foundation of estoppels that bind by deed and by contract, the editors adopt Spencer Bower's unificatory project by the identification of the reliance-based estoppels as aspects of a single principle preventing a change of position that would be unfair by reason of responsibility for prejudicial reliance. From this follow the views: that reliance-based estoppels have common requirements of responsibility, causation and prejudice; that estoppel by representation of fact is, like the other reliance-based estoppels, a rule of law; that the result of estoppel by representation of fact may, accordingly, be mitigated on equitable grounds to avoid injustice; that the result of an estoppel by convention depends on whether its subject matter is factual, promissory or proprietary; that a reliance-based estoppel (other than a proprietary estoppel, which uniquely generates a cause of action) may be deployed to complete a cause of action where, absent the estoppel, a cause of action would not lie, unless it would unacceptably subvert a rule of law (in particular the doctrine of consideration); that an estoppel as to a right in or over property generates a discretionary remedy; and that the prohibition on the deployment of a promissory estoppel as a sword should be understood as an application of the defence of illegality, viz that an estoppel may not unacceptably subvert a statute or rule of law.
Oral, Head and Neck Oncology and Reconstructive Surgery is the first multidisciplinary text to provide readers with a system for managing adult head and neck cancers based upon stage. Using an evidence-based approach to the management and treatment of a wide variety of clinical conditions, the extensive experience of the author and contributors in head and neck surgery and oncology are highlighted throughout the text. This includes computer aided surgical simulation, intraoperative navigation, robotic surgery, endoscopic surgery, microvascular reconstructive surgery, molecular science, and tumor immunology. In addition, high quality photos and illustrations are included, which are easily accessible on mobile devices. - Management protocols and outcomes assessment provide clear guidelines for managing problems related to adult head and neck oncology and reconstructive surgery. - State-of-the art guidance by recognized experts details current techniques as well as technological advances in head and neck/cranio-maxillofacial surgery and oncology. - Evidence-based content details the latest diagnostic and therapeutic options for treating a wide-variety of clinical problems with an emphasis on surgical technique and outcomes. - Multidisciplinary approach reflects best practices in managing head and neck oncology and cranio-maxillofacial surgery. - 900 highly detailed images clearly demonstrate pathologies and procedures. - Designed for the modern classroom which lets you access important information anywhere through mobile tablets and smart phones.
Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome
Completely revised to meet the demands of today's trainee and practicing plastic surgeon, Craniofacial, Head and Neck Surgery Pediatric Plastic Surgery, Volume 3 of Plastic Surgery, 4th Edition, features new full-color clinical photos, dynamic videos, and authoritative coverage of hot topics in the field. Editor-narrated PowerPoint presentations offer a step-by-step audio-visual walkthrough of techniques and procedures in plastic surgery. - Offers evidence-based advice from a diverse collection of experts to help you apply the very latest advances in craniofacial, head and neck, and pediatric plastic surgery and ensure optimal outcomes. - Provides updated coverage of: Aesthetic reconstruction of the nose; Orbito-maxillary reconstruction; Cheek and lip reconstruction; Facial paralysis; Facial transplant; and Surgical management of migraine headaches. - Highlights the latest information on Computerised surgical planning in orthognathic surgery; Computerised surgical planning in craniofacial, head and neck surgery; and Rotation advancement. - Includes brand-new color clinical photos, videos, and lectures. - Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, videos, and references from the book on a variety of devices.
Head and Neck Imaging, by Drs. Peter M. Som and Hugh D. Curtin, delivers the encyclopedic and authoritative guidance you've come to expect from this book – the expert guidance you need to diagnose the most challenging disorders using today's most accurate techniques. New state-of-the-art imaging examples throughout help you recognize the imaging presentation of the full range of head and neck disorders using PET, CT, MRI, and ultrasound. Enhanced coverage of the complexities of embryology, anatomy, and physiology, including original color drawings and new color anatomical images from Frank Netter, help you distinguish subtle abnormalities and understand their etiologies. - Compare your imaging findings to thousands of crystal-clear examples representing every type of head and neck disorder. - Gain an international perspective from global authorities in the field. - Find information quickly with a logical organization by anatomic region. - Master the latest approaches to image-guided biopsies and treatments. - Utilize PET/CT scanning to its fullest potential, including head and neck cancer staging, treatment planning, and follow up to therapy. - Visualize head and neck anatomy better than ever before with greatly expanded embryology, physiology and anatomy content, including original drawings and new color anatomical images. - Grasp the finer points of head and neck imaging quickly with more images, more detail in the images, and more anatomic atlases with many examples of anatomic variants. Access the complete content- and illustrations online at www.expertconsult.com - fully searchable!
The validity of a contract can be undermined by factors affecting contractual consent. Issues of contractual validity frequently arise for consideration in all types of litigation, not least commercial disputes. This book provides practitioners and academics with an invaluable reference tool, which will enable them to navigate the complex issues of vitiation of contract. When contractual disputes arise, there are a variety of vitiating factors which may be relied on to undermine a contract’s validity. This book provides a comprehensive examination of all the factors vitiating contractual consent from fraud, misrepresentation, non-disclosure, and mistake, to duress, undue influence, unconscionable bargains, and includes chapters on incapacity and unfairness. Each chapter gives a thorough account of the law on each of these vitiating factors, together with an overview of the remedies available. The book’s introduction considers the theoretical foundations of the law in this area. The book will be an invaluable reference tool for lawyers involved in all types of contractual disputes. It will also be a useful reference for academics and postgraduate students of commercial law.
Now in full color, Maxillofacial Surgery, 3rd Edition covers the entire specialty of maxillofacial surgery, including craniofacial deformity, oral surgery, trauma, and oncology. Unlike other OMFS texts where the contributors are singly boarded in oral surgery, this richly illustrated text boasts OMFS contributors who are all dual boarded in both oral surgery and medicine. Thoroughly updated with evidence-based content, it addresses the advances in technology and procedures providing oral and maxillofacial surgeons with new and exciting treatment options. And with print and digital formats, it is easy to use in any setting. - Authoritative guidance on oral and maxillofacial surgery by internationally recognized experts in the field. - 2,800 illustrations, including radiographs and full color artwork and clinical photos, provide clinicians and OMS residents with a clear visual guide to diagnoses, key concepts, and surgical techniques, as well as examples of preoperative and postoperative results. - A multidisciplinary approach reflects the best practices in the disciplines of oral and maxillofacial surgery, head and neck surgery, plastic surgery, and otolaryngology. - Covers contemporary techniques and technological advances at the forefront of maxillofacial surgery. - Evidence-based content supports the newest, most up-to-date diagnostic and therapeutic options available for a wide variety of clinical problems. - Key Points and Pitfalls boxes clearly identify the most important information, as well as potential problem areas that can arise when treating patients. - Available in print and digital formats that can be easily accessed via mobile tablets and smart phones in any setting, making it perfect for the modern student of surgery. - NEW! Full-color images clearly depict pathologies, concepts, and procedures. - EXPANDED and UPDATED! Expanded from 82 to 111 chapters with thoroughly revised content that reflects current information and advances in OMS, so clinicians and students can depend on this text as their go-to resource on oral maxillofacial surgery. - NEW! 29 new state-of-the-art chapters covering new topics, including the salivary glands, thyroid and parathyroid glands, tissue engineering, navigational surgery, 3D modeling, and lasers in OMFS. - NEW! Two new editors, Professors Brennan and Schliephake, and new section editors and contributors have helped bring advances in the field of oral and maxillofacial surgery and offer a fresh perspective. - UPDATED! Expanded chapter on cancer keeps you in the know.
The seabed in southern Scandinavia contains numerous traces of a submerged landscape that is thought to be the remnant of a once important habitat for Mesolithic hunter-gatherers. Large parts of this landscape were gradually flooded by rising seas between 9500 and 4000 BC and perceptions of the Maglemose culture (9500-6400 BC) have, consequently, been based almost exclusively on former inland settlements. As a result, Early and Late Mesolithic societies have been understood as almost diametrically opposed with regards to their reliance upon marine resources and their degree of sedentism. The main objective of the book is to investigate two questions that are directly related to our current understanding of the populations of the now submerged areas: 1) Do we have a representative picture of the spread of Early Mesolithic sites in southern Scandinavia, or does the weighting towards inland sites reflect the fact that coastal sites have not been identified below present-day sea-level? 2) How did sea-level changes impact Mesolithic populations at different temporal and spatial scales, and how were these experienced from 8000-4000 BC? The book presents an extensive and up-to-date review of various types of evidence from the Boreal period such as faunal remains, fishing instruments, d13C values in bones, settlement positions and available marine resources. These are used to discuss the extent to which marine resources were utilised in the Maglemose culture. Another central component of this book is a series of new coastline models made to determine the Mesolithic sea-level changes / coastline positions. The eight new coastline models are created to facilitate new evaluations of possible relationships between sea-level changes and cultural changes. On the basis of the new coastline models the book also presents the preliminary results of 47 diver investigations conducted with the aim of identifying potential coastal settlements from the Maglemose culture.
Current, comprehensive, and evidence-based Braunwald's Heart Disease remains the most trusted reference in the field and the leading source of reliable cardiology information for practitioners and trainees worldwide. The fully updated 12th Edition continues the tradition of excellence with dependable, state-of-the-art coverage of new drugs, new guidelines, more powerful imaging modalities, and recent developments in precision medicine that continue to change and advance the practice of cardiovascular medicine. Written and edited by global experts in the field, this award-winning text is an unparalleled multimedia reference for every aspect of this complex and fast-changing area. - Offers balanced, dependable content on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. - Includes 76 new contributing authors and 14 new chapters that cover Artificial intelligence in Cardiovascular Medicine; Wearables; Influenza, Pandemics, COVID-19, and Cardiovascular Disease; Tobacco and Nicotine Products in Cardiovascular Disease; Cardiac Amyloidosis; Impact of the Environment on Cardiovascular Health, and more. - Features a new introductory chapter Cardiovascular Disease: Past, Present, and Future by Eugene Braunwald, MD, offering his unique, visionary approach to the field of cardiology. Dr. Braunwald also curates the extensive, bimonthly online updates that include "Hot Off the Press" (with links to Practice Update) and "Late-Breaking Clinical Trials". - Provides cutting-edge coverage of key topics such as proteomics and metabolomics, TAVR, diabetocardiology, and cardio-oncology. - Contains 1,850 high-quality illustrations, radiographic images, algorithms, and charts, and provides access to 215 videos called out with icons in the print version. - Highlights the latest AHA, ACC, and ESC guidelines to clearly summarize diagnostic criteria and clinical implications. - Provides tightly edited, focused content for quick, dependable reference. Flexible format options include either one or two volumes in print, as well as a searchable eBook with ongoing updates. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
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