The validity of a contract can be undermined by factors affecting contractual consent. Issues of contractual validity frequently arise for consideration in all types of litigation, not least commercial disputes. This book provides practitioners and academics with an invaluable reference tool, which will enable them to navigate the complex issues of vitiation of contract. When contractual disputes arise, there are a variety of vitiating factors which may be relied on to undermine a contract’s validity. This book provides a comprehensive examination of all the factors vitiating contractual consent from fraud, misrepresentation, non-disclosure, and mistake, to duress, undue influence, unconscionable bargains, and includes chapters on incapacity and unfairness. Each chapter gives a thorough account of the law on each of these vitiating factors, together with an overview of the remedies available. The book’s introduction considers the theoretical foundations of the law in this area. The book will be an invaluable reference tool for lawyers involved in all types of contractual disputes. It will also be a useful reference for academics and postgraduate students of commercial law.
Chronic obstructive pulmonary disease (COPD), which encompasses both chronic bronchitis and emphysema, is one of the most common respiratory conditions of adults in the developed world. Asthma and COPD: Basic Mechanisms and Clinical Management provides a unique, authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it is a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.* Highlights distinguishing features between asthma and COPD* Reviews benefits and limitations of current therapies* Summarises key information in two-colour artwork * Extensively referenced to primary literature
This issue of Clinics in Chest Medicine is Guest Edited by Peter J. Barnes FRS, FMedSci from Imperial College London and will fosus on COPD. Article topics include epidemiology, pathophysiology, cellular and molecular mechanisms and comorbidities of COPD, diagnosis and phenotype of COPD, pulmonary rehabilitation, asthma and COPD, biomarkers, bronchodilators, non invasive ventialtion, and new drug therapies.
During the past decade, major scientific advances have occured in our understanding of asthma and associated diseases of the airways such as rhinitis and sinusitis. These developments have been accompanied by new, potent and safe medications and better drug delivery systems. As a result, most children with asthma and similar problems involving the nose, eyes and ears can now have their conditions completely controlled so that they no longer suffer from breathlessness, cough or wheeze. The end result is an improved quality of life for children who no longer need miss school, or recreational activities. Conquering Childhood Asthma will show most asthmatics how to live a healthier and happier life, hardly aware that they have asthma. We hope that parents will enjoy understanding and participating actively with their doctors in the care of their children.
During the past decade, major scientific advances have occured in our understanding of asthma and associated diseases of the airways such as rhinitis and sinusitis. These developments have been accompanied by new, potent and safe medications and better drug delivery systems. As a result, most people with asthma and similar problems involving the nose, eyes and ears can now have their conditions completely controlled so that they no longer suffer from breathlessness, cough or wheeze. The end result is an improved quality of life for people who no longer need miss school, work or recreational activities. Conquering Asthma will show most asthmatics how to live a healthier and happier life, hardly aware that they have asthma. We hope that you will enjoy understanding and participating actively with your doctor in the self care of your disease.
Widely recognized as the gold standard reference in the field, Rosen’s Breast Pathology provides comprehensive, up-to-date information on diseases of the breast from renowned experts at four leading medical centers, masterfully edited by Dr. Paul P. Rosen. The revised fifth edition covers the latest advances in immunohistochemical, pathobiological, and molecular aspects of benign and malignant breast diseases, helping you reach an accurate diagnosis with confidence. It’s an ideal reference for all physicians and medical personnel who require a thorough knowledge of breast pathology, including pathologists, surgeons, oncologists, radiologists, and radiation oncologists.
The central argument of this book is that the univocal ontology and corresponding immanent metaphysics of the French philosopher Gilles Deleuze (1925-1995) can provide a theoretical perspective capable of accounting for the complex nature of world politics. Drawing on a wide variety of Deleuze’s writings, it develops a thorough investigation of his ontology and metaphysics as they pertain to core questions of world politics such as power, identity, hierarchy, space, time, territory and the state. The book explores the dynamics of contemporary world politics and issues by focusing on the ‘anti’ or ‘alter-globalization movement’ (AGM). It analyses several approaches to social and political theory which deal explicitly with the AGM including global governance theory, international relations, social movement theory, Marxism, and post-Marxism. These are contrasted with a larger Deleuzian theory which can be of use when addressing the diffuse, and often paradoxical aspects of world politics. Deleuze’s work poses a major challenge to traditional understanding of global politics and this book will be of considerable interest to those with an interest in social and political theory, critical international relations and globalization studies.
This book provides a definitive critical introduction to service user views and involvement. It addresses both the theoretical and practical issues of service user involvement, and includes initiatives on the impact and outcomes from involvement.
Whales: large, mysterious, intelligent, and endangered. Over the years, large-scale commercial whaling has gradually devoured several species, resulting in a global moratorium issues by the International Whaling Commission (IWC) in 1986. Current debate centers on the validity of this ban given strong opposition from whaling communities in Norway and Japan, Iceland’s withdrawal frm the IWC, and reputed recovery of some whale populations. The International Politics of Whaling is a fascinating study of the politics, environmental dilemmas, and ethical questions surrounding this highly controversial issue. Peter Stoett seeks to clarify the multidimensional nature of whaling as well as its relation to other crucial environmental concerns such as ozone depletion, global warming, and marine pollution. Stoett combines a sensitivity to ecological questios with a hard assessment of the political realities of the international community in order to assess this important issue.
This biographical dictionary of some 3,000 photographers (and workers in related trades), active in a vast area of North America before 1866, is based on extensive research and enhanced by some 240 illustrations, most of which are published here for the first time. The territory covered extends from central Canada through Mexico and includes the United States from the Mississippi River west to, but not including, the Rocky Mountain states. Together, this volume and its predecessor, Pioneer Photographers of the Far West: A Biographical Dictionary, 1840-1865, comprise an exhaustive survey of early photographers in North America and Central America, excluding the eastern United States and eastern Canada. This work is distinguished by the large number of entries, by the appealing narratives that cover both professional and private lives of the subjects, and by the painstaking documentation. It will be an essential reference work for historians, libraries, and museums, as well as for collectors of and dealers in early American photography. In addition to photographers, the book includes photographic printers, retouchers, and colorists, and manufacturers and sellers of photographic apparatus and stock. Because creators of moving panoramas and optical amusements such as dioramas and magic lantern performances often fashioned their works after photographs, the people behind those exhibitions are also discussed.
There are one billion smokers on the planet today and up to half will die from their habit. According to the World Health Organization, approximately one person dies every six seconds from tobacco use. Despite the negative effects of smoking, the healthcare profession is not entirely smoke-free; an issue which must be addressed as this group is on the frontlines of tobacco control. This book presents the findings of more than 360 surveys of smoking among doctors, dentists and nurses, as well as students in these fields. Much can be learned from the data; the most important being a comprehensive understanding of how many healthcare professionals smoke, in what country, and at what stage in their career. The gathering of such data is the focus of this book.
Revised and updated, this edition covers general principles of overdose management; the automonic nervous system, neurotransmitters and drugs; drugs used in psychiatry; cardiac drugs; agents that burn; gases and abnormal haemoglobin formation; the
Preclinical and Clinical Modulation of Anticancer Drugs focuses on the theoretical and practical approaches to designing and enacting modulation principles. Each class of anticancer drug and the different types of modulators used within each drug class are discussed within individual chapters. The molecular and biochemical rationale for the use of specific modulators is discussed in detail, and preclinical and clinical implications of the data are integrated into each chapter. Mechanisms of drug resistance and the reasons behind circumventing the resistant phenotype are covered. The book will interest cancer chemotherapists, pharmacologists, oncologists, biochemists, and experimental therapeutics researchers, in addition to students studying the principles of drug discovery and protocol design.
With the combined expertise of leading hand surgeons and therapists, Rehabilitation of the Hand and Upper Extremity, 6th Edition, by Drs. Skirven, Osterman, Fedorczyk and Amadio, helps you apply the best practices in the rehabilitation of hand, wrist, elbow, arm and shoulder problems, so you can help your patients achieve the highest level of function possible. This popular, unparalleled text has been updated with 30 new chapters that include the latest information on arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management. An expanded editorial team and an even more geographically diverse set of contributors provide you with a fresh, authoritative, and truly global perspective while new full-color images and photos provide unmatched visual guidance. Access the complete contents online at www.expertconsult.com along with streaming video of surgical and rehabilitation techniques, links to Pub Med, and more. Provide the best patient care and optimal outcomes with trusted guidance from this multidisciplinary, comprehensive resource covering the entire upper extremity, now with increased coverage of wrist and elbow problems. Apply the latest treatments, rehabilitation protocols, and expertise of leading surgeons and therapists to help your patients regain maximum movement after traumatic injuries or to improve limited functionality caused by chronic or acquired conditions. Effectively implement the newest techniques detailed in new and updated chapters on a variety of sports-specific and other acquired injuries, and chronic disorders. Keep up with the latest advances in arthroscopy, imaging, vascular disorders, tendon transfers, fingertip injuries, mobilization techniques, traumatic brachial plexus injuries, and pain management See conditions and treatments as they appear in practice thanks to detailed, full-color design, illustrations, and photographs. Access the full contents online with streaming video of surgical and rehabilitation techniques, downloadable patient handouts, links to Pub Med, and regular updates at www.expertconsult.com. Get a fresh perspective from seven new section editors, as well as an even more geographically diverse set of contributors.
The book includes recommendations for COPD from published guidelines (eg, the GOLD, ATS, and NICE guidelines) and presents them in the context of relevant clinical treatment issues. This is an in-depth guide on the management of COPD, concentrating on the impact of COPD on a patient as well as how healthcare professionals can intervene and educate the patient at an early stage and thereby slow the onset of severe symptoms.
This book aims to help readers interpret, and reflect on, their reading more effectively. It presents doctrines of ancient and renaissance rhetoric (an education in how to write well) as questions or categories for interpreting one’s reading. The first chapter presents the questions. Later chapters use rhetorical theory to bring out the implications of, and suggest possible answers to, the questions: about occasion and audience (chapter 2), structure and disposition (3), narrative (4), argument (5), further elements of content, such as descriptions, comparisons, proverbs and moral axioms, dialogue, and examples (6), and style (7). Chapter eight describes ways of gathering material, formulating arguments and writing about the texts one reads. The conclusion considers the wider implications of taking a rhetorical approach to reading. The investigation of rhetoric’s questions is interspersed with analyses of texts by Chaucer, Sidney, Shakespeare, Fielding and Rushdie, using the questions. The text is intended for university students of literature, especially English literature, and rhetoric, and their teachers.
Head and Neck Imaging, by Drs. Peter M. Som and Hugh D. Curtin, delivers the encyclopedic and authoritative guidance you've come to expect from this book – the expert guidance you need to diagnose the most challenging disorders using today's most accurate techniques. New state-of-the-art imaging examples throughout help you recognize the imaging presentation of the full range of head and neck disorders using PET, CT, MRI, and ultrasound. Enhanced coverage of the complexities of embryology, anatomy, and physiology, including original color drawings and new color anatomical images from Frank Netter, help you distinguish subtle abnormalities and understand their etiologies. - Compare your imaging findings to thousands of crystal-clear examples representing every type of head and neck disorder. - Gain an international perspective from global authorities in the field. - Find information quickly with a logical organization by anatomic region. - Master the latest approaches to image-guided biopsies and treatments. - Utilize PET/CT scanning to its fullest potential, including head and neck cancer staging, treatment planning, and follow up to therapy. - Visualize head and neck anatomy better than ever before with greatly expanded embryology, physiology and anatomy content, including original drawings and new color anatomical images. - Grasp the finer points of head and neck imaging quickly with more images, more detail in the images, and more anatomic atlases with many examples of anatomic variants. Access the complete content- and illustrations online at www.expertconsult.com - fully searchable!
Classical Philosophy is the first of a series of books in which Peter Adamson aims ultimately to present a complete history of philosophy, more thoroughly but also more enjoyably than ever before. In short, lively chapters, based on the popular History of Philosophy podcast, he offers an accessible, humorous, and detailed look at the emergence of philosophy with the Presocratics, the probing questions of Socrates, and the first full flowering of philosophy with the dialogues of Plato and the treatises of Aristotle. The story is told 'without any gaps', discussing not only such major figures but also less commonly discussed topics like the Hippocratic Corpus, the Platonic Academy, and the role of women in ancient philosophy. Within the thought of Plato and Aristotle, the reader will find in-depth introductions to major works, such as the Republic and the Nicomachean Ethics, which are treated in detail that is unusual in an introduction to ancient philosophy. Adamson looks at fascinating but less frequently read Platonic dialogues like the Charmides and Cratylus, and Aristotle's ideas in zoology and poetics. This full coverage allows him to tackle ancient discussions in all areas of philosophy, including epistemology, metaphysics, philosophy of language, philosophy of science, ethics and politics. Attention is also given to the historical and literary context of classical philosophy, with exploration of how early Greek cosmology responded to the poets Homer and Hesiod, how Socrates was presented by the comic playwright Aristophanes and the historian Xenophon, and how events in Greek history may have influenced Plato's thought. This is a new kind of history which will bring philosophy to life for all readers, including those coming to the subject for the first time.
Peter Adamson offers an accessible, humorous tour through a period of eight hundred years when some of the most influential of all schools of thought were formed: from the third century BC to the sixth century AD. He introduces us to Cynics and Skeptics, Epicureans and Stoics, emperors and slaves, and traces the development of Christian and Jewish philosophy and of ancient science. Chapters are devoted to such major figures as Epicurus, Lucretius, Cicero, Seneca, Plotinus, and Augustine. But in keeping with the motto of the series, the story is told 'without any gaps,' providing an in-depth look at less familiar topics that remains suitable for the general reader. For instance, there are chapters on the fascinating but relatively obscure Cyrenaic philosophical school, on pagan philosophical figures like Porphyry and Iamblichus, and extensive coverage of the Greek and Latin Christian Fathers who are at best peripheral in most surveys of ancient philosophy. A major theme of the book is in fact the competition between pagan and Christian philosophy in this period, and the Jewish tradition also appears in the shape of Philo of Alexandria. Ancient science is also considered, with chapters on ancient medicine and the interaction between philosophy and astronomy. Considerable attention is paid also to the wider historical context, for instance by looking at the ascetic movement in Christianity and how it drew on ideas from Hellenic philosophy. From the counter-cultural witticisms of Diogenes the Cynic to the subtle skepticism of Sextus Empiricus, from the irreverent atheism of the Epicureans to the ambitious metaphysical speculation of Neoplatonism, from the ethical teachings of Marcus Aurelius to the political philosophy of Augustine, the book gathers together all aspects of later ancient thought in an accessible and entertaining way.
Ancient philosophers had always been fascinated by religion. From the first century BC onwards the traditionally hostile attitude of Greek and Roman philosophy was abandoned in favour of the view that religion was a source of philosophical knowledge. This book studies that change, not from the usual perspective of the history of religion, but as part of the wider tendency of Post-Hellenistic philosophy to open up to external, non-philosophical sources of knowledge and authority. It situates two key themes, ancient wisdom and cosmic hierarchy, in the context of Post-Hellenistic philosophy and traces their reconfigurations in contemporary literature and in the polemic between Jews, Christians and pagans. Overall, Post-Hellenistic philosophy displayed a relatively high degree of unity in its ideas on religion, which should not be reduced to a preparation for Neoplatonism.
One of the key tools in effectively managing critical illness is the use of mechanical ventilator support. This essential text helps you navigate this rapidly evolving technology and understand the latest research and treatment modalities. A deeper understanding of the effects of mechanical ventilation will enable you to optimize patient outcomes while reducing the risk of trauma to the lungs and other organ systems. A physiologically-based approach helps you better understand the impact of mechanical ventilation on cytokine levels, lung physiology, and other organ systems. The latest guidelines and protocols help you minimize trauma to the lungs and reduce patient length of stay. Expert contributors provide the latest knowledge on all aspects of mechanical ventilation, from basic principles and invasive and non-invasive techniques to patient monitoring and controlling costs in the ICU. Comprehensive coverage of advanced biological therapies helps you master cutting-edge techniques involving surfactant therapy, nitric oxide therapy, and cytokine modulators. Detailed discussions of both neonatal and pediatric ventilator support helps you better meet the unique needs of younger patients.
Thisbook isnotatextbook tobecomeacquainted with thelaws ofnature. An elementaryknowledgeaboutlawsofnature,inparticularthelawsofphysics,is presupposed. Thebookisratherintendedtoprovideaclari?cationofconcepts and properties of the laws of nature. The authors would like to emphasise that this book has been developed – created – as a real teamwork. Although the chapters (and in some cases parts of the chapters) were originally written by one of the two authors, all of them were discussed thoroughly and in detail and have been revised and complemented afterwards. Even if both authors were in agreement on most of the foundational issues discussed in the book, they did not feel it necessary to balance every viewpoint. Thus some individual and personal di?erence or emphasis will still be recognisable from the chapters written by the di?erent authors. In this sense the authors feel speci?cally responsible for the chapters as follows: Mittelstaedt for Chaps. 4, 9. 3, 10, 11. 2, 12, 13 and Weingartner for Chaps. 1, 2, 3, 5, 7, 8. 2, 9. 2, 9. 4. The remaining parts are joint sections. Most of the chapters are formulated as questions and they begin with arguments pro and contra. Then a detailed answer is proposed which contains a systematic discussion of the question. This is the respective main part of the chapter. It sometimes begins with a survey of the problem by giving some important answers to it from history (cf. Chaps. 6 and 9).
This text gives a comprehensive discussion of the range of treatments available in asthma therapy and aims to provide a reference manual for both the specialist and trainee in respiratory medicine.
Take advantage of this unique book - the first single-volume resource to explore all important aspects of neurogenic inflammation. An unrivaled compilation of up-to-date information, Neurogenic Inflammation contains chapters written by recognized authorities in their areas of expertise. It covers the basic mechanisms and the pathophysiological implications of neurogenic inflammatory processes and points to novel therapeutic strategies in the field of inflammatory and related diseases. The book highlights the many systems and mechanisms involved in neurogenic inflammation, including vasodilatation, plasma extravasation, leukocyte adhesion, smooth muscle contraction, exocrine gland secretion, and recruitment of inflammatory cells. The authors discuss the contribution of neurogenic inflammation to human diseases, such as migraine, asthma, arthritis, and inflammatory bowel disease, linked to the ubiquitous distribution of sensory nerves to organs and tissues at both the somatic and visceral level. Neurogenic Inflammation is the clear choice for a one-step, authoritative guide to the latest developments in this dynamic field.
Peter Anstey presents a thorough and innovative study of John Locke's views on the method and content of natural philosophy. Focusing on Locke's Essay concerning Human Understanding, but also drawing extensively from his other writings and manuscript remains, Anstey argues that Locke was an advocate of the Experimental Philosophy: the new approach to natural philosophy championed by Robert Boyle and the early Royal Society who were opposed to speculative philosophy. On the question of method, Anstey shows how Locke's pessimism about the prospects for a demonstrative science of nature led him, in the Essay, to promote Francis Bacon's method of natural history, and to downplay the value of hypotheses and analogical reasoning in science. But, according to Anstey, Locke never abandoned the ideal of a demonstrative natural philosophy, for he believed that if we could discover the primary qualities of the tiny corpuscles that constitute material bodies, we could then establish a kind of corpuscular metric that would allow us a genuine science of nature. It was only after the publication of the Essay, however, that Locke came to realize that Newton's Principia provided a model for the role of demonstrative reasoning in science based on principles established upon observation, and this led him to make significant revisions to his views in the 1690s. On the content of Locke's natural philosophy, it is argued that even though Locke adhered to the Experimental Philosophy, he was not averse to speculation about the corpuscular nature of matter. Anstey takes us into new terrain and new interpretations of Locke's thought in his explorations of his mercurialist transmutational chymistry, his theory of generation by seminal principles, and his conventionalism about species.
The benchmark text in obstetrical procedures updated and expanded to reflect current practice * New chapter authors * New Study Guide with CME credit * More than 470 illustrations * Study Guide with 1,000 questions and answers This 2nd Edition of the comprehensive Operative Obstetrics first published in 1995, continues to bring you step-by-step instructions for every major surgical procedure performed in current obstetrical practice. Leading obstetricians across the country have written the nearly 40 chapters, most of them contributors to the 1st Edition. However, you'll recognize names of several new contributors to this 2nd Edition.
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