Features a practical approach to the analysis of biomedical data via mathematical methods and provides a MATLAB® toolbox for the collection, visualization, and evaluation of experimental and real-life data Applied Mathematics for the Analysis of Biomedical Data: Models, Methods, and MATLAB® presents a practical approach to the task that biological scientists face when analyzing data. The primary focus is on the application of mathematical models and scientific computing methods to provide insight into the behavior of biological systems. The author draws upon his experience in academia, industry, and government–sponsored research as well as his expertise in MATLAB to produce a suite of computer programs with applications in epidemiology, machine learning, and biostatistics. These models are derived from real–world data and concerns. Among the topics included are the spread of infectious disease (HIV/AIDS) through a population, statistical pattern recognition methods to determine the presence of disease in a diagnostic sample, and the fundamentals of hypothesis testing. In addition, the author uses his professional experiences to present unique case studies whose analyses provide detailed insights into biological systems and the problems inherent in their examination. The book contains a well-developed and tested set of MATLAB functions that act as a general toolbox for practitioners of quantitative biology and biostatistics. This combination of MATLAB functions and practical tips amplifies the book’s technical merit and value to industry professionals. Through numerous examples and sample code blocks, the book provides readers with illustrations of MATLAB programming. Moreover, the associated toolbox permits readers to engage in the process of data analysis without needing to delve deeply into the mathematical theory. This gives an accessible view of the material for readers with varied backgrounds. As a result, the book provides a streamlined framework for the development of mathematical models, algorithms, and the corresponding computer code. In addition, the book features: Real–world computational procedures that can be readily applied to similar problems without the need for keen mathematical acumen Clear delineation of topics to accelerate access to data analysis Access to a book companion website containing the MATLAB toolbox created for this book, as well as a Solutions Manual with solutions to selected exercises Applied Mathematics for the Analysis of Biomedical Data: Models, Methods, and MATLAB® is an excellent textbook for students in mathematics, biostatistics, the life and social sciences, and quantitative, computational, and mathematical biology. This book is also an ideal reference for industrial scientists, biostatisticians, product development scientists, and practitioners who use mathematical models of biological systems in biomedical research, medical device development, and pharmaceutical submissions.
Fully updated to meet the demands of the 21st-century surgeon, this title provides you with all the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Edited by Drs. Mathes and Hentz in its last edition, this six-volume plastic surgery reference now features new expert leadership, a new organization, new online features, and a vast collection of new information - delivering all the state-of-the-art know-how you need to overcome any challenge you may face. Renowned authorities provide evidence-based guidance to help you make the best clinical decisions, get the best results from each procedure, avoid complications, and exceed your patients' expectations.
Understanding organogenesis is central to current efforts to direct stem cell differentiation and function in the context of a complex organ. Defects in organogenesis are often the major manifestations of human genetic disease syndromes. This volume describes the development of 10 major organ systems, reviewed by experts in each, to provide an up-to-date overview for researchers within and outside the field, students, teachers and clinicians. - Summarizes the key morphological and cellular events - Emphasizes up-to-date research relating to molecular control mechanisms - Draws on a range of model vertebrates and contemporary experimental approaches, including lessons learnt from human developmental disease - Distils common themes and differences for comparative studies - Highlights key remaining questions and sets the agenda for future research
Fully updated to meet the demands of the 21st-century surgeon, Principles, Volume 1 of Plastic Surgery, 3rd Edition, provides you with the most current knowledge and techniques in the principles of plastic surgery, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Apply the very latest advances in plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Stay abreast of the latest information on business practices, stem cell therapy, and tissue engineering, and walk through the history, psychology, and core principles of reconstructive and aesthetic plastic surgery. Know what to look for and what results you can expect with over 1,000 color photographs and illustrations. Easily find the answers you need with a more templated, user-friendly, high-yield presentation.
Fully updated to meet the demands of the 21st-century surgeon, Plastic Surgery provides you with all the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Edited by Drs. Mathes and Hentz in its last edition, this six-volume plastic surgery reference now features new expert leadership, a new organization, new online features, and a vast collection of new information - delivering all the state-of-the-art know-how you need to overcome any challenge you may face. Renowned authorities provide evidence-based guidance to help you make the best clinical decisions, get the best results from each procedure, avoid complications, and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in every area of plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Master the latest on stem cell therapy, tissue engineering, and inductive therapies • aesthetic surgical techniques and nonsurgical treatments • conjoined twin separation and other craniofacial surgery advances • microsurgical lymphatic reconstruction, super microsurgery, and sternal fixation • autologous lipofilling of the breast • nerve transfers in hand surgery, hand allotransplantation, and functional prosthetics • and much, much more. Easily find the answers you need with a new organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity, plus a more templated, user-friendly, high-yield presentation. Visualize procedures more clearly through an abundance of completely redrawn full-color illustrations and new color clinical photographs. Access the complete, fully searchable contents of each volume online, download all the tables and figures, view 160 procedural videos, and take advantage of additional content and images at www.expertconsult.com!
Engages in key debates in contemporary consumption and identity studies, yet presents a firmly grounded study that will complement the more speculative writing about shopping, place and identity that has developed in recent years.
This book is an account of two dimension of state and nation building in France and Spain since the seventeenth century--the invention of a national boundary line and the making of Frenchmen and Spaniards. It is also a history of Catalan rural society in the Cerdanya, a valley in the eastern Pyrenees divided between Spain and France in 1659. This study shuttles between two levels, between the center and the periphery. It connects the "macroscopic" political and diplomatic history of France and Spain, from the Old Regime monarchies to the national territorial states of the later nineteenth century; and the "molecular" history--the historical ethnography--of Catalan village communities, rural nobles, and peasants in the borderland. On the frontier, these two histories come together, and they can be told as one. This title is part of UC Press's Voices Revived program, which commemorates University of California Press's mission to seek out and cultivate the brightest minds and give them voice, reach, and impact. Drawing on a backlist dating to 1893, Voices Revived makes high-quality, peer-reviewed scholarship accessible once again using print-on-demand technology. This title was originally published in 1990. This book is an account of two dimension of state and nation building in France and Spain since the seventeenth century--the invention of a national boundary line and the making of Frenchmen and Spaniards. It is also a history of Catalan rural society in
This book focuses on the crucial role that relationships play in the lives of teenagers. The authors particularly examine the ways that healthy relationships can help teens avoid such common risk behaviors as substance abuse, dating violence, sexual assault, and unsafe sexual practices. Addressing the current lack of effective prevention programs for teens, they present new strategies for encouraging healthy choices. The book first traces differences between the “rules of relating” for boys and girls and discusses typical and atypical patterns of experimentation in teens. The authors identify the common link among risk behaviors: the relationship connection. In the second part of the book, they examine the principles of successful programs used by schools and communities to cultivate healthy adolescent development. An illuminating conclusion describes the key ingredients for engaging adolescents, their parents, teachers, and communities in the effort to promote healthy, nonviolent relationships among teens.
Elizabeth A. Kaye specializes in communications as part of her coaching and consulting practice. She has edited Requirements for Certification since the 2000-01 edition.
This user-friendly reference tool presents clinical scenarios and discusses some practical complementary and alternative therapies available in dermatology. It focuses on peer-reviewed data that are suitable for use in a conventional dermatology practice and helps dermatologists guide their patients when faced with questions regarding integrative dermatology using an evidence-based, reader-friendly, and case-focused approach. Within the field of dermatology, there is a marked void in the understanding of complementary and alternative approaches, though dermatologists frequently use off-label therapies to manage chronic conditions. They do so, however, with a range of success and potentially considerable side effect profiles. Handbook of Integrative Dermatology is a must-have tool for any practicing dermatologist.
This text provides an introduction to the applications and implementations of partial differential equations. The content is structured in three progressive levels which are suited for upper–level undergraduates with background in multivariable calculus and elementary linear algebra (chapters 1–5), first– and second–year graduate students who have taken advanced calculus and real analysis (chapters 6-7), as well as doctoral-level students with an understanding of linear and nonlinear functional analysis (chapters 7-8) respectively. Level one gives readers a full exposure to the fundamental linear partial differential equations of physics. It details methods to understand and solve these equations leading ultimately to solutions of Maxwell’s equations. Level two addresses nonlinearity and provides examples of separation of variables, linearizing change of variables, and the inverse scattering transform for select nonlinear partial differential equations. Level three presents rich sources of advanced techniques and strategies for the study of nonlinear partial differential equations, including unique and previously unpublished results. Ultimately the text aims to familiarize readers in applied mathematics, physics, and engineering with some of the myriad techniques that have been developed to model and solve linear and nonlinear partial differential equations.
In January 2002, forty-six-year-old Christa Worthington was found stabbed to death in the kitchen of her Cape Cod cottage, her curly-haired toddler clutching her body. A former Vassar girl and scion of a prominent local family, Christa had abandoned a glamorous career as a fashion writer for a simpler life on the Cape, where she had an affair with a married fisherman and had his child. After her murder, evidence pointed toward several local men who had known her. Yet in 2005, investigators arrested Christopher McCowen, a thirty-four-year-old African-American garbage collector with an IQ of 76. The local headlines screamed,'Black Trash Hauler Ruins Beautiful White Family' and 'Black Murderer Apprehended in Fashion Writer Slaying,' while the sole evidence against McCowen was a DNA match showing that he'd had sex with Worthington prior to her murder. There were no fingerprints, no witnesses, and although the state medical examiner acknowledged there was no evidence of rape, after a five-week trial -- replete with conflicting testimony and accusations of crime scene contamination -- McCowen was condemned to three lifetime sentences with no parole. Rarely has a homicide trial been refracted so clearly through the prism of those who engineered it. Bestselling author and biographer Peter Manso dug deep into the case, and the results were explosive. The Cape DA indicted the author, threatening him with fifty years in prison. In this exhaustively researched and vividly accessible book, Manso bares the anatomy of a horrific murder, a botched investigation rife with bias, and one of the most grossly unjust verdicts in modern trial history."--Page 4 of cove
Core Techniques in Operative Neurosurgery provides step-by-step guidance to help you effectively manage the full range of cranial and spinal neurosurgical disorders. Drs. Rahul Jandial, Paul McCormick, and Peter Black offer their expertise and experience in consistent chapters that cover the indications and contraindications, pitfalls, tips and tricks, and more for each procedure. With access to the full text and procedural videos online at www.expertconsult.com, you’ll have everything you need to minimize risk and get the best results. Master each technique by watching step-by-step videos online at www.expertconsult.com, and access the book’s complete text and illustrations. Find information easily with consistent chapters that include indications and contraindications, common pitfalls, bailout options, and tips and tricks from the experts for each procedure. Apply the expertise and experience of the world’s leading authorities in the field of neurosurgery.
This bestselling textbook will introduce undergraduate bioengineering students to the fundamental concepts and techniques, with the basic theme of integrative bioengineering. It covers bioengineering of several body systems, organs, tissues, and cells, integrating physiology at these levels with engineering concepts and approaches; novel developments in tissue engineering, regenerative medicine, nanoscience and nanotechnology; state-of-the-art knowledge in systems biology and bioinformatics; and socio-economic aspects of bioengineering.One of the distinctive features of the book is that it is integrative in nature (integration of biology, medicine and engineering, across different levels of the biological hierarchy, and basic knowledge with applications). It is unique in that it covers fundamental aspects of bioengineering, cutting-edge frontiers, and practical applications, as well as perspectives of bioengineering development. Furthermore, it covers important socio-economical aspects of bioengineering such as ethics and entrepreneurism.
For the last 30 years, polyphenols were in the centre of research work worldwide. Silymarin, an extract from a medicinal plant Silybum marianum, also known as milk thistle, has a special place in this group, having been used in human medicine for the management of liver diseases since ancient times. Accumulating scientific evidence indicates that silymarin is characterised by a wide range of protective pharmacological activities and this topic has received tremendous attention in recent years. However, until now there has been no single monograph addressing major questions related to silymarin chemistry, biochemistry and practical applications. The goal of this book is to provide up to date information about silymarin chemistry, biochemistry and molecular mechanisms of protective actions of this phytochemical with a special emphasis to its vitagene- and transcription factor-modulating properties. Silymarin applications in human diseases, including hepatoprotection, neuroprotection, anti-diabetic, anti-arthritis and other protective activities are reviewed. Immunomodulating, anti-inflammatory, anti-toxic protective activities of silymarin are characterised in detail. Practical applications of silymarin in poultry and animal industry with a special emphasis on its protective roles in gut health maintenance are also presented. This book will be of practical importance to medical and pharmaceutical scientists, including medical doctors, pharmacists, consultants, etc. as well as to poultry/animal scientists, poultry producers, nutritionists and vets, as well as to students of medical, biological and agricultural backgrounds. It can also be of interest for researchers in areas related to physiology, biochemistry, nutrition and veterinary medicine.
This book is a comprehensive exposition of FET modeling, and is a must-have resource for seasoned professionals and new graduates in the RF and microwave power amplifier design and modeling community. In it, you will find descriptions of characterization and measurement techniques, analysis methods, and the simulator implementation, model verification and validation procedures that are needed to produce a transistor model that can be used with confidence by the circuit designer. Written by semiconductor industry professionals with many years' device modeling experience in LDMOS and III-V technologies, this was the first book to address the modeling requirements specific to high-power RF transistors. A technology-independent approach is described, addressing thermal effects, scaling issues, nonlinear modeling, and in-package matching networks. These are illustrated using the current market-leading high-power RF technology, LDMOS, as well as with III-V power devices.
Comprehensive and fully up to date, Dr. Peter Neligan's six-volume masterwork, Plastic Surgery, 5th Edition, remains the gold standard text in this complex area of surgery. Completely revised to meet the demands of both the trainee and experienced surgeon, it features new, full-color clinical photos, procedural videos, and lectures across all six volumes. Bonus material online includes additional text, images, and over 200 procedural videos that help you improve your mastery of the latest techniques. - Easily find the answers you need with an organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery and Pediatric Plastic Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity. Each easily readable, individual volume is a standalone comprehensive text full of salient and applicable anatomy and techniques. - Key procedures include gender affirmation management and surgery, microsurgery and surgery for lymphedema, aesthetic facial surgery, aesthetic body surgery, and the education, training and practice of plastic surgery. - New digital video preface by Dr. Neligan addresses the changes across all six volumes. - New treatment and decision-making algorithms added to chapters where applicable. - New video lectures and editor-narrated slide presentations offer a step-by-step audiovisual walkthrough of techniques and procedures. - Four new international experts join the editorial team, and lead editor Peter C. Neligan creates a cohesive tone throughout the chapters and content across all six volumes. - Evidence-based advice from a diverse collection of experts allows you to apply the very latest advances in every area of plastic surgery and ensure optimal outcomes. - Purchase only the volumes you need or own the entire set, with the ability to search across all six volumes online!
Prison and Jail Administration: Practice and Theory, Second Edition has been completely revised an updated to include the latest research and best practices in corrections management. This book is the compendium for correctional administration courses, covering everything from organizational structure and management accountability to food service, personnel corruption, and the impact of technology in penal institutions. With chapters contributed by over sixty leading academics and practitioners, this text provides students with a unique balance of practice and theory. Suggested readings, learning objectives, discussion questions, and a glossary help students gain an in-depth understanding of the material.
The extended metropolitan regions of Southeast Asia are the dynamic cores of their national economies and societies and the frontiers of accelerating globalization. This title explores ways of moving beyond outmoded paradigms of the Third World City or a Southeast Asian city 'type'.
Insurance Economics brings together the economic analysis of decision making under risk, risk management and demand for insurance among individuals and corporations, objectives pursued and management tools used by insurance companies, the regulation of insurance, and the division of labor between private and social insurance. Appropriate both for advanced undergraduate and graduate students of economics, management, and finance, this text provides the background required to understand current research. Predictions derived from theoretical arguments are not merely stated, but also related to empirical evidence. Throughout the book, conclusions summarize key results, helping readers to check their knowledge and comprehension. Issues discussed include paradoxes in decision making under risk and attempts at their resolution, moral hazard and adverse selection including the possibility of a “death spiral”, and future challenges to both private and social insurance such as globalization and the availability of genetic information. This second edition has been extensively revised. Most importantly, substantial content has been added to represent the evolution of risk-related research. A new chapter, Insurance Demand II: Nontraditional Approaches, provides a timely addition in view of recent developments in risk theory and insurance. Previous discussions of Enterprise Risk Management, long-term care insurance, adverse selection, and moral hazard have all been updated. In an effort to expand the global reach of the text, evidence and research from the U.S. and China have also been added.
Zakim and Boyer's Hepatology-the defining work in hepatology-presents comprehensive coverage of both basic science and clinically relevant developments so you can provide the best possible patient care. Drs. Thomas Boyer, Michael Manns, and Arun Sanyal have reorganized and updated the contents of this trusted global reference to reflect today's more clinical approach to hepatology. They bring you up to date on hot topics including HIV Co-Infection Drug Toxicity, Hepatocellular Carcinoma (HCC), and much more. This new streamlined edition is now a single volume with access to the fully searchable contents and an image bank online at www.expertconsult.com making it easier to find the treatment information you need. Effectively treat all liver diseases currently seen in clinical practice with authoritative guidance from leading international authorities. Reinforce your foundation in basic science with the concise Pathophysiology of Therapeutic Targets section. See clear presentations of liver disease through hundreds of detailed, color illustrations. Explore topics further with up-to-date references that direct you to the significant literature. Access the complete, fully searchable contents of the book online at www.expertconsult.com, along with a downloadable image bank and complete list of references. Stay current on new developments in the field through five new chapters on Pathogenesis Liver Injury in HBV, HCV; HCC; Imaging and Non-Invasive DX Liver Disease CT, US, Fibroscan, MRI; HIV Co-Infection Drug Toxicity; and HBC, HCV in Non-Liver Transplant Patients, plus comprehensive updates throughout. Apply best practices with reorganized and updated content that reflects today's need for a more clinical approach to hepatology. Reference key information more easily thanks to streamlined content that now fits into one volume.
Recognizing rapidly ageing population is one key concern faced by cities and the challenge it would present to healthcare system, this book looks at ageing in China’s population as well as the delivery and financing of long-term care (LTC) in China. The book compares key features of long-term care insurance (LTCI) schemes in 15 pilot cities and evaluates the sustainability of various financing models adopted by the cities in the LTCI schemes. The book uses an interpretive case study approach to give an in-depth look into the LTC models in three pilot cities – Qingdao, Nantong, and Shanghai. The three cities represent three different models of financing and delivering LTC. To assess how effective the LTC models in these three cities are, the book uses five criteria, including utilization of medical resources, cost, equity, quality of care and sustainability. Also, the authors discuss how the financing and delivery of LTC can be improved in China, the impact of the 2019 coronavirus (COVID-19) pandemic on older adults in need of LTC in the country and the implications of China’s LTCI reform for other countries. The book will be a useful reference to scholars and policy-makers who look at urban ageing and healthcare costs and delivery.
In Buying Military Transformation, Peter Dombrowski and Eugene Gholz analyze the United States military's ongoing effort to capitalize on information technology. New ideas about military doctrine derived from comparisons to Internet Age business practices can be implemented only if the military buys technologically innovative weapons systems. Buying Military Transformation examines how political and military leaders work with the defense industry to develop the small ships, unmanned aerial vehicles, advanced communications equipment, and systems-of-systems integration that will enable the new military format. Dombrowski and Gholz's analysis integrates the political relationship between the defense industry and Congress, the bureaucratic relationship between the firms and the military services, and the technical capabilities of different types of businesses. Many government officials and analysts believe that only entrepreneurial start-up firms or leaders in commercial information technology markets can produce the new, network-oriented military equipment. But Dombrowski and Gholz find that the existing defense industry will be best able to lead military-technology development, even for equipment modeled on the civilian Internet. The U.S. government is already spending billions of dollars each year on its "military transformation" program-money that could be easily misdirected and wasted if policymakers spend it on the wrong projects or work with the wrong firms. In addition to this practical implication, Buying Military Transformation offers key lessons for the theory of "Revolutions in Military Affairs." A series of military analysts have argued that major social and economic changes, like the shift from the Agricultural Age to the Industrial Age, inherently force related changes in the military. Buying Military Transformation undermines this technologically determinist claim: commercial innovation does not directly determine military innovation; instead, political leadership and military organizations choose the trajectory of defense investment. Militaries should invest in new technology in response to strategic threats and military leaders' professional judgments about the equipment needed to improve military effectiveness. Commercial technological progress by itself does not generate an imperative for military transformation. Clear, cogent, and engaging, Buying Military Transformation is essential reading for journalists, legislators, policymakers, and scholars.
Does it seem you’ve formulated a rock-solid strategy, yet your firm still can’t get ahead? If so, construct a solid foundation for business execution—an IT infrastructure and digitized business processes to automate your company’s core capabilities. In Enterprise Architecture as Strategy: Creating a Foundation for Business Execution, authors Jeanne W. Ross, Peter Weill, and David C. Robertson show you how. The key? Make tough decisions about which processes you must execute well, then implement the IT systems needed to digitize those processes. Citing numerous companies worldwide, the authors show how constructing the right enterprise architecture enhances profitability and time to market, improves strategy execution, and even lowers IT costs. Though clear, engaging explanation, they demonstrate how to define your operating model—your vision of how your firm will survive and grow—and implement it through your enterprise architecture. Their counterintuitive but vital message: when it comes to executing your strategy, your enterprise architecture may matter far more than your strategy itself.
Following up on the fables and stories surrounding political sovereignty—once theological, now often nationalist—Peter Gratton's The State of Sovereignty takes aim at the central concepts surrounding the post-9/11 political environment. Against those content to conceptualize what has been called the "sovereign exception," Gratton argues that sovereignty underwent profound changes during modernity, changes tracked by Rousseau, Arendt, Foucault, Agamben, and Derrida. Each of these thinkers investigated the "fictions" and "illusions" of claims to sovereign omnipotence, while outlining what would become the preeminent problems of racism, nationalism, and biopower. Gratton illustrates the principal claims that tie these philosophers together and, more importantly, what lessons they offer, perhaps in spite of themselves, for those thinking about the future of politics. His innovative readings will open new ground for new and longtime readers of these philosophers alike, while confronting how their critiques of sovereignty reshape our conceptions of identity, freedom, and selfhood. The result not only fills a long-standing need for an up-to-date analysis of the concept of sovereignty but is also a tour de force engaging readers in the most important political and philosophical questions today.
Discover research from across the United States and around the world on children exposed to domestic violence! If you are a member of a helping, medical, or legal profession, Children Exposed to Domestic Violence: Current Issues in Research, Intervention, Prevention, and Policy Development will help you explore research, assessments, interventions, and policy and prevention for children, victims of battering, batterers, and their families. This important book focuses on various aspects of spousal/partner abuse and child maltreatment. Comprehensive and thorough, Children Exposed to Domestic Violence focuses on three major sections: theoretical and research issues, intervention and prevention strategies, and policy development from an international perspective. Some of the important issues you will examine include: exploring the importance of partnerships between the domestic violence front-line workers and researchers at universities addressing the thorny issues of parenting in abused women assessing all areas of children's adjustment as well as their various relationships that may be problematic investigating the results of a quarter century research on men who batter by focusing on the crucial link between exposure to violence in childhood and adult marital behavior understanding the role of physiological and environmental factors as central to the role in domestic violence exploring the challenges faced by shelter staff in providing services to children who accompany their mother to find refuge examining new ideas for primary prevention programs in schools understanding policy and legislative implications of the growing body of literature on the impact of exposure to violence on children Children Exposed to Domestic Violence exemplifies the serious challenges faced by social workers, educators, policymakers, psychologists and others in helping professions working with children who have been exposed to domestic violence. You will gain insight into the vast amount of research that has taken place in the last ten years on this problem that will assist you with creating research ideas, interventions, prevention programs, and policies concerning children exposed to domestic violence.
This new edition of the book series dedicated to “Progress in Epileptic Disorders” is the result of a recently held unique gathering of international experts that debated on the prognostic and therapeutic issues raised by the management of first unprovoked seizures and of newly diagnosed epilepsy. Current knowledge on natural evolution of a first seizure, the role of co-morbid conditions, the impact of immediate versus delayed treatment and recent guidelines are thoroughly addressed. The new ideas and suggestions that emerge from this book offer challenging perspectives for both patient care and clinical as well as fundamental research. The first section of the book includes an up to date review of epidemiological data, encompassing the natural evolution of single unprovoked seizures, risk factors for recurrent seizures, and the potential for comorbid conditions such as depression, migraine, ADHD, and dysimmune metabolic disorders to promote the development of epilepsy. The impact of febrile convulsions on long-term brain hyperexcitability is also discussed. The second section concentrates on therapeutic issues, concerning the management of single unprovoked seizures and newly diagnosed epilepsy. These include the impact of immediate versus deferred treatment and the choice of the most appropriate antiepileptic drug therapy. Several methodological issues are addressed in parallel with the chapters, providing new insights into domains, such as the representativeness of the patient population in the studies under consideration, as well as the limitations and pitfalls of most randomised controlled trials. The value of these trials in the development of treatment guidelines is also discussed.
Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. This multimedia e-dition includes not only the printed reference, but also access to the complete contents online, fully searchable, with regular updates and much more. The expertise of the contributors, the scope of the coverage, and the versatile, multimedia format all make this the ultimate reference for the practicing cardiologist. Locate the answers you need fast, thanks to a user-friendly, full-color design, complete with more than 1,500 color illustrations. Glean clinically actionable information quickly with Clinical Practice Points in every chapter. Access the complete contents of the 2-volume set online, fully searchable, plus regular updates to reflect the latest clinical developments · Focused Reviews · Commentaries · Late-Breaking Trials · and more. Apply the latest knowledge in your field with 7 new chapters on Acute Heart Failure · Device Therapy of Heart Failure · Emerging Therapies for Heart Failure · Complementary and Alternative Approaches to Management · Prevention and Management of Stroke · Hypertrophic Cardiomyopathy · and Coronary Arteriography Guidelines. Get fresh perspectives on your practice with contributions from more than 20 brand-new authors.
This book brings together new work by leading syntactic theorists from the USA and Europe on a central aspect of syntactic and morphological theory: it explores the role of agreement morphology in the morphosyntactic realization of a verb's arguments. The authors examine the differences and parallels between nonconfigurational, pronominal- agreement languages; configurational languages which allow pronoun drop (for example, "Is coming" for "He is coming"); languages that allow pronoun drop in particular constructions only; and languages which always require overt syntactic determiner phrases as arguments. The book considers whether the morphological properties of agreement play a role in determining which of these types a language belongs to and how far languages differ with respect to the argumental status of their agreement and syntactic determiner phrases. The authors explore these and related issues and problems in the context of a wide range of languages. Their book will interest linguists at graduate level and above concerned with morphosyntactic theory, linguistic typology, and the interactions of syntax and morphology in different languages.
The Northwest Foster Care Alumni Study found that quality foster care services for children pay big dividends when they grow up. Key investments in highly trained staff, low caseloads and robust complementary services can dramatically reduce rates of mental disorders and substance abuse. This book offers a model foster care programme.
This book examines the fundamental question of how legislators and other rule-makers should handle remembering and forgetting information (especially personally identifiable information) in the digital age. It encompasses such topics as privacy, data protection, individual and collective memory, and the right to be forgotten when considering data storage, processing and deletion. The authors argue in support of maintaining the new digital default, that (personally identifiable) information should be remembered rather than forgotten. The book offers guidelines for legislators as well as private and public organizations on how to make decisions on remembering and forgetting personally identifiable information in the digital age. It draws on three main perspectives: law, based on a comprehensive analysis of Swiss law that serves as an example; technology, specifically search engines, internet archives, social media and the mobile internet; and an interdisciplinary perspective with contributions from various disciplines such as philosophy, anthropology, sociology, psychology, and economics, amongst others.. Thanks to this multifaceted approach, readers will benefit from a holistic view of the informational phenomenon of “remembering and forgetting”. This book will appeal to lawyers, philosophers, sociologists, historians, economists, anthropologists, and psychologists among many others. Such wide appeal is due to its rich and interdisciplinary approach to the challenges for individuals and society at large with regard to remembering and forgetting in the digital age.
Statistics for Sport and Exercise Studies guides the student through the full research process, from selecting the most appropriate statistical procedure, to analysing data, to the presentation of results, illustrating every key step in the process with clear examples, case-studies and data taken from real sport and exercise settings. Every chapter includes a range of features designed to help the student grasp the underlying concepts and relate each statistical procedure to their own research project, including definitions of key terms, practical exercises, worked examples and clear summaries. The book also offers an in-depth and practical guide to using SPSS in sport and exercise research, the most commonly used data analysis software in sport and exercise departments. In addition, a companion website includes more than 100 downloadable data sets and work sheets for use in or out of the classroom, full solutions to exercises contained in the book, plus over 1,300 PowerPoint slides for use by tutors and lecturers. Statistics for Sport and Exercise Studies is a complete, user-friendly introduction to the use of statistical tests, techniques and procedures in sport, exercise and related subjects. Visit the companion website at: www.routledge.com/cw/odonoghue
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