A rich, wide-ranging history of ignorance in all its forms, from antiquity to the present day A Seminary Coop Notable Book of 2023 "Ignorance: A Global History explores the myriad ways in which 'not-knowing' affects our lives, sometimes for good, sometimes for ill."--Michael Dirda, Washington Post Throughout history, every age has thought of itself as more knowledgeable than the last. Renaissance humanists viewed the Middle Ages as an era of darkness, Enlightenment thinkers tried to sweep superstition away with reason, the modern welfare state sought to slay the "giant" of ignorance, and in today's hyperconnected world seemingly limitless information is available on demand. But what about the knowledge lost over the centuries? Are we really any less ignorant than our ancestors? In this highly original account, Peter Burke examines the long history of humanity's ignorance across religion and science, war and politics, business and catastrophes. Burke reveals remarkable stories of the many forms of ignorance--genuine or feigned, conscious and unconscious--from the willful politicians who redrew Europe's borders in 1919 to the politics of whistleblowing and climate change denial. The result is a lively exploration of human knowledge across the ages, and the importance of recognizing its limits.
What ants, bees, fish, and smart swarms can teach us about communication, organization, and decision-making The modern world may be obsessed with speed and productivity, but twenty-first-century humans actually have much to learn from the ancient instincts of swarms. A fascinating new take on the concept of collective intelligence and its colorful manifestations in some of our most complex problems, The Smart Swarm introduces a compelling new understanding of the real experts on solving our own complex problems relating to such topics as business, politics, and technology. Based on extensive globe-trotting research, this lively tour from National Geographic reporter Peter Miller introduces thriving throngs of ant colonies, which have inspired computer programs for streamlining factory processes, telephone networks, and truck routes; termites, used in recent studies for climate-control solutions; schools of fish, on which the U.S. military modeled a team of robots; and many other examples of the wisdom to be gleaned about the behavior of crowds-among critters and corporations alike. In the tradition of James Surowiecki's The Wisdom of Crowds and the innovative works of Malcolm Gladwell, The Smart Swarm is an entertaining yet enlightening look at small-scale phenomena with big implications for us all.
Oncogene proteins are proteins coded by oncogenes. They include proteins resulting from the fusion of an oncogene and another gene. This new book presents the latest research in the field from around the world.
Business/IT Fusion - How to move beyond alignment and transform IT in your organization is a business book authored by Peter Hinssen. It discusses an approach to IT management that moves beyond the classic model of business/IT alignment: alignment focused on the collaboration between business and IT, Hinssen suggests that the future evolution in IT lies in the convergence of the two parties: integrating IT into the business rather than treating it as asupplier. The work is presented as a guidebook to "IT 2.0
Macular Surgery, Second Edition serves as a comprehensive and contemporary review of macular diseases and their management. An exhaustive review of the latest proven surgical techniques and therapies for treatment of macular disorders is provided, with emphasis on proven techniques from extensive reviews of controlled clinical trials. Specific chapters of the book are devoted to age-related macular degeneration, diabetic retinopathy, macular holes, epiretinal membranes, subretinal hemorrhage, and choroidal neovascularization. An entire section is devoted to prevention of complications from macular surgery. All chapters are written by leading experts within the field.
This book evaluates Central Asian regionalism by analyzing the impact of Russia and China on physical infrastructure in the region. The narrative builds a picture of the nature of the two powers’ influence on the development of regional connectivity in Central Asia. The study covers the 30-year period since the dissolution of the Soviet Union, with a focus on the last decade preceding the global pandemic. Qualitative research methods, i.e., documentary analysis, media analysis, and elite interviews, are implemented to explore how activities of Russia and China impact regional cooperation among Central Asian states. Multiple case studies of projects in the networked sectors of infrastructure, i.e., transportation, energy, and telecommunications, are used to build the argument and demonstrate the ways in which Russia’s and China’s engagement influence regional connectivity. The book is of interest to the scholars who study international relations in Eurasia, major power relations, Sino-Russian relations, China foreign policy, international institutions in Asia, multilateralism, and regionalism. The empirical depth of the book attracts attention of area studies scholars who focus on Central Asia, Central Eurasia, and any of the five Central Asian states. Additionally, the scholars who analyze the roles of hard infrastructure find the book particularly important. The in-depth cases on multilateral financial institutions and regional networks, particularly energy, transportation, and telecommunication, are of great value to those interested in these respective sectors.
Banishing troublesome and deviant people from society was common in the early modern period. Many European countries removed their paupers, convicted criminals, rebels and religious dissidents to remote communities or to their colonies where they could be simultaneously punished and, perhaps, contained and reformed. Under British rule, poor Irish, Scottish Jacobites, English criminals, Quakers, gypsies, Native Americans, the Acadian French in Canada, rebellious African slaves, or vulnerable minorities like the Jews of St. Eustatius, were among those expelled and banished to another place. This book explores the legal and political development of this forced migration, focusing on the British Atlantic world between 1600 and 1800. The territories under British rule were not uniform in their policies, and not all practices were driven by instructions from London, or based on a clear legal framework. Using case studies of legal and political strategies from the Atlantic world, and drawing on accounts of collective experiences and individual narratives, the authors explore why victims were chosen for banishment, how they were transported and the impact on their lives. The different contexts of such banishment – internal colonialism ethnic and religious prejudice, suppression of religious or political dissent, or the savageries of war in Europe or the colonies – are examined to establish to what extent displacement, exile and removal were fundamental to the early British Empire.
Signal Transduction, 2e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium Extensive conceptual color artwork to assist with comprehension of key topics Instrumental margin notes highlight milestones in signaling mechanisms
Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.
Experts in herbicide research and development - chemists and plant physiologists - have written 15 chapters that review all aspects pertinent to Peroxidizing Herbicides, compounds of topical interest since extremely low use rates ensure high environmental safety. This comprehensive review will be welcomed as a unique and timely compilation of the current status of peroxidizing herbicide research and development. It will be of interest to professional chemists and biologists in agrochemical companies, universities and agricultural colleges.
This handbook is intended for the advanced specialist and for the practitioner interested in the application of lasers in medicine. It provides state-of-the art summaries of all available medical laser systems and the indications for their clinical use. The first part introduces basic laser physics, including laser-tissue interactions as well as technical equipment and particular techniques developed for medical use in connection with laser. The second part of the text covers all areas of laser application in medicine presented by senior specialists from different countries, each having extensive practical experience.
A wide-ranging introduction to the multi-faceted history of Asia—from early origins to the present Asia Past and Present is an expansive survey of the social, political, and economic history of the continent from the Paleolithic era to the early 21st century. As there is no physically discrete continent, rather an arbitrary division of the Eurasian landmass, this book focuses on terrain that encompasses India, Pakistan, Afghanistan, Central Asia, China, Korea, Japan, Mongolia, the Russian Far East, and Southeast Asia—the area which most modern scholars identify as Asia. Offering broad chronological and topical coverage of Asia, this book examines subjects including written languages, religions and philosophies, concepts of monarchy, militarism, independence and nation building, and more. Particular focus is placed on the varying levels of influence the core cultures of India and China have had on the continent in a multitude of socio-political areas. Historical dialogues of how colonies, later emerging nations, blended traditional Asian culture and Western political and economic models of modernization complement contemporary discussions of globalization, nuclear tensions, and growing demands for greater individual freedom. Written in an engaging, accessible style, this book: Covers of a wide range of topics, perspectives, geographic regions, and time periods Highlights India and China as the pre 19th century cultural cores of Asia Presents a relatable political-cultural narrative framework Discusses contemporary themes including gender, sexual orientation, the environment, and Western and Islamic influence on Asian culture Includes coverage of commonly underrepresented regions such as the Himalayan nations, Maldives, and New Guinea Asia Past and Present: A Brief History is a valuable resource for undergraduate courses where Asian cultures are introduced, and in courses on Asian politics, diplomacy, environmental issues, and socio-economics.
Exploring Shakespeare's intellectual interest in placing both characters and audiences in a state of uncertainty, mystery, and doubt, this book interrogates the use of paradox in Shakespeare's plays and in performance. By adopting this discourse-one in which opposites can co-exist and perspectives can be altered, and one that asks accepted opinions, beliefs, and truths to be reconsidered-Shakespeare used paradox to question love, gender, knowledge, and truth from multiple perspectives. Committed to situating literature within the larger culture, Peter Platt begins by examining the Renaissance culture of paradox in both the classical and Christian traditions. He then looks at selected plays in terms of paradox, including the geographical site of Venice in Othello and The Merchant of Venice, and equity law in The Comedy of Errors, Merchant, and Measure for Measure. Platt also considers the paradoxes of theater and live performance that were central to Shakespearean drama, such as the duality of the player, the boy-actor and gender, and the play/audience relationship in the Henriad, Hamlet, As You Like It, Twelfth Night, Antony and Cleopatra, The Winter's Tale, and The Tempest. In showing that Shakespeare's plays create and are created by a culture of paradox, Platt offers an exciting and innovative investigation of Shakespeare's cognitive and affective power over his audience.
Updated to reflect today’s practice guidelines, the new edition of this comprehensive text remains the definitive resource on all aspects of renal transplantation, including immunological, pathological, psychological and ethical considerations. It examines evaluation, management, and procurement of living and deceased donor kidneys, the selection of suitable recipients, interpretation of graft dysfunction, and expected survival based upon a large database of information. There are comprehensive chapters on pediatric renal transplantation and on renal transplantation in the developing world. Extensive tables and figures and comprehensive lists of references with each chapter enhance its value to the transplant team. A multidisciplinary approach from internationally renowned contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. This 6th edition remains the balanced reference you need to stay apprised of issues important to successful kidney transplantation. Provides a comprehensive description of surgical techniques, immunosuppressive methods, outcomes, risks, and medical considerations related to kidney transplantation, both in adults and children, in one convenient reference. Presents more than 335 superb illustrations-50 in full color-that demonstrate key concepts and nuances of techniques. Features a multidisciplinary approach from contributors from around the world-many new to this edition-offers practice-applicable guidance for all members of the transplant team, with coverage encompassing applied science, clinical information, and surgical procedures. Offers evidence-based decision making advice in renal transplantation-supported by a wealth of data in chapters written by internationally recognized experts-to help you make the most informed clinical decisions. Offers new tables and figures as well as revised and updated chapters that report new data and present current practice guidelines. Features a new chapter on transplantation in the sensitized patient to assist you with transplant cases that present unique challenges. Describes the latest preclinical and clinical immunosuppressive strategies, to help you see the link between clinical issues and the basic sciences. Offers tissue typing methodology updates, equipping you with the newest methods of assessing immune responses to the kidney. Features a new chapter on chronic allograft nephropathy.
Value-Driven Business Process Management gives business leaders in any industry the rationale and methods for using BPM to gain clarity on how their business operates and develop the ability to put new ideas into action quickly. Readers learn how to redirect their focus from a "method-and-tool" view of BPM to a more broadly informed view of BPM as a management approach and put it to practical use to initiate action within their organization.
Technology marches on, bringing new dangers-and new oppor-tunities. As cloud computing, social, mobile, big data, predictive analytics, and the Internet of Things are baked into more and more business processes, they will rapidly reshape how business gets done, today and tomorrow. Today companies are struggling to come to grips with these forces that introduce unprecedented complexity. Business Process Management (BPM) has delivered benefits over a long period of time and continues to do so. But as process scopes expand to meet the nexus of these forces, BPM needs to be enhanced and extended in order to harness the exploding complexity to gain competitive advantage. The idea of having all the intelligence centrally managed and delivered is outmoded and challenging, if not impossible. This book provides insights and strategies for transforming current centralized BPM approaches by exploiting decentralized, distributed intelligence in the form of intelligent agent technology. Agent-oriented BPM (aoBPM) will allow BPM to take on all of what is expected of it going forward. The book provides a starting point that will help you know what is coming, and how to think about addressing it. It's about your organization's journey toward the future. And as William Gibson wrote in The Economist, "The future is already here-it's just not evenly distributed." Sinur, Odell and Fingar, seasoned business-technology thought leaders, are just the right mix to interweave these concepts. The time is ripe for aoBPM, and this book is a telling and timely way to introduce it.
The Blueprint for Business Objects provides a clear and concise guide to making informed decisions about emerging object technology and to mastering the skills you need to make effective use of the technology in business. Driven by rapidly developing technology and the globalization of markets and competition, companies are using information technology to make radical changes in the way they organize work and conduct business. As companies redesign themselves, you'll need additional knowledge and skills to master business re-engineering and the advanced information systems that make re-engineering possible. Based on the workplace experiences of several major corporations, this book presents a framework designed for business and information systems professionals meeting this challenge. It provides the reader with a road map, starting at the level of initial concepts and moving up to the mastery level. It also includes information on how to select and find additional learning resources.
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