This book is a selection from the articles that I have written over a period of more than twenty years. Since the focus of my research interests has shifted several times during this period, it would be difficult to identify a common theme for all the papers in the volume. Following the Swedish tradition, I therefore present this as a smörgåsbord of philosophical and cognitive issues that I have worked on. To create some order, I have organized the sixteen papers into five general sections: (1) Decision theory; (2) belief revision and nonmonotonic logic; (3) induction; (4) semantics and pragmatics; and (5) cognition and evolution. Having said this, I still think that there is a common theme to my work over the years: The dynamics of thought. My academic interests have all the time dealt with aspects of how different kinds of knowledge should be represented, and, in particular, how changes in knowledge will affect thinking. Hence the title of the book.
Combinatorial chemistry has taken the pharmaceutical industry by storm over the past ten to fifteen years. There has been a massive investment in automation by pharmaceutical companies and a demand for graduates/PhDs with experience and knowledge of combinatorial chemistry. These days the academic education of chemists and biologists is gradually converging, so those entering the pharmaceutical industry need to be not only chemistry graduates but also biologists applying their biological knowledge to chemistry. Many chemists, however, still require experience in biological methods and similarly biologists have not yet realized the power of chemical methods. This book will therefore help ease the transition from biology into chemistry and vice versa, for those working in the combinatorial chemistry field. Because combinatorial chemistry evolved from the requirements of the biology field, the authors have written this book with both biologists and chemists in mind. Combinatorial chemistry is a new and highly influential area of modern synthetic chemistry based on efficient, parallel synthesis of molecules, as opposed to the use of several synthetic steps, to produce many sets of compounds for biological evaluation. The techniques used in this area are key to the discovery of new drug compounds in the pharmaceutical and agrochemical industries. Combinatorial Methods in Chemistry and Biology describes the origins, basics and techniques used both in combinatorial chemistry and molecular biology. Key features: * First book to cover combinatorial methods in both chemistry and biology - ideal for those with either a chemical or biological background. * Introductory text - ideal for newcomers to the field. * Covers a wide swathe of techniques and topics - providing beginners with a complete overview of the field. * Contains chapters on supporting material and linkers, two important areas in the field. * Up-to-date and topical. This volume will be of key interest to technicians/scientists working in the pharmaceutical industry with backgrounds in either biology or chemistry. It will also be invaluable to students - postgraduates studying chemistry and molecular biology or those chemistry/molecular biology undergraduates at universities where combinatorial chemistry is taught as a module.
Fashion Writing and Criticism provides students with the tools to critique fashion with skill and style. Explaining the history and theory of criticism, this innovative text demonstrates how the tradition of criticism has developed and how this knowledge can be applied to fashion, enabling students to acquire the methods and proper vocabulary to be active critics themselves. Integrating history and theory, this innovative book explains the development of fashion writing, the theoretical basis on which it sits, and how it might be improved and applied. Through concise snapshot case studies, top international scholars McNeil and Miller analyse fashion excerpts in relation to philosophical ideas and situate them within historical contexts. Case studies include classic examples of fashion writing, such as Diana Vreeland at Harper's Bazaar and Richard Martin on Karl Lagerfeld, as well as contemporary examples such as Suzy Menkes and the blogger Tavi. Accessibly written, Fashion Writing and Criticism enables readers to understand, assess and make value judgments about the fascinating and changeable field of fashion. It is an invaluable text for students and researchers alike, studying fashion, journalism, history and media studies.
Is there a way out of anxiety, depression, overeating, fear, phobias, addiction, insomnia, trauma, and low self-esteem - without taking pills? Is there really an alternative to Prozac and anti-depressants? Can you really recapture the simple joy of living? The answer to all theses questions is Yes! This book will show you: How your subconscious mind has been programmed to make you feel the way you feel. How these programs can be rapidly changed through the right kind of hypnotherapy. How even your most difficult feelings and emotions can help you change your life for the better. How you can live a balanced, meaningful life and move forward in confidence and harmony with yourself and your world ,
This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Reproduction is among the most basic of human biological functions, both for our distant ancestors and for ourselves, whether we live on the plains of Africa or in North American suburbs. Our reproductive biology unites us as a species, but it has also been an important engine of our evolution. In the way our bodies function today we can see both the imprint of our formative past and implications for our future. It is the infinitely subtle and endlessly dramatic story of human reproduction and its evolutionary context that Peter T. Ellison tells in On Fertile Ground. Ranging from the latest achievements of modern fertility clinics to the lives of subsistence farmers in the rain forests of Africa, this book offers both a remarkably broad and a minutely detailed exploration of human reproduction. Ellison, a leading pioneer in the field, combines the perspectives of anthropology, stressing the range and variation of human experience; ecology, sensitive to the two-way interactions between humans and their environments; and evolutionary biology, emphasizing a functional understanding of human reproductive biology and its role in our evolutionary history. Whether contrasting female athletes missing their periods and male athletes using anabolic steroids with Polish farm women and hunter-gatherers in Paraguay, or exploring the intricate choreography of an implanting embryo or of a nursing mother and her child, On Fertile Ground advances a rich and deeply satisfying explanation of the mechanisms by which we reproduce and the evolutionary forces behind their design.
The iconic Periodic Table of the Elements is now in its most satisfyingly elegant form. This is because all the 'gaps' corresponding to missing elements in the seventh row, or period, have recently been filled and the elements named. But where do these names come from? For some, usually the most recent, the origins are quite obvious, but in others - even well-known elements such as oxygen or nitrogen - the roots are less clear. Here, Peter Wothers explores the fascinating and often surprising stories behind how the chemical elements received their names. Delving back in time to explore the history and gradual development of chemistry, he sifts through medieval manuscripts for clues to the stories surrounding the discovery of the elements, showing how they were first encountered or created, and how they were used in everyday lives. As he reveals, the oldest-known elements were often associated with astronomical bodies, and connections with the heavens influenced the naming of a number of elements. Following this, a number of elements, including hydrogen and oxygen, were named during the great reform of chemistry, set amidst the French Revolution. While some of the origins of the names were controversial (and indeed incorrect - some saying, for instance, that oxygen might be literally taken to mean 'the son of a vinegar merchant'), they have nonetheless influenced language used around the world to this very day. Throughout, Wothers delights in dusting off the original sources, and bringing to light the astonishing, the unusual, and the downright weird origins behind the names of the elements so familiar to us today.
For 125 years, physicians have relied on Manson's Tropical Diseases for a comprehensive clinical overview of this complex and fast-changing field. The fully revised 24th Edition, Dr. Jeremy Farrar, along with an internationally recognized editorial team, global contributors, and expert authors, delivers the latest coverage on parasitic and infectious diseases from around the world. From the difficult to diagnose to the difficult to treat, this highly readable, award-winning reference prepares you to effectively handle whatever your patients may have contracted. - Covers all of tropical medicine in a comprehensive manner, general medicine in the tropics, and non-clinical issues regarding public health and ethics. - Serves as an indispensable resource for physicians who treat patients with tropical diseases and/or will be travelling to the tropics, or who are teaching others in this area. - Contains a new section on 21st Century Drivers of Tropical Medicine, with chapters covering Poverty and Inequality, Public Health in Settings of Conflict and Political Instability, Climate Change, and Medical Product Quality and Public Health. - Includes all-new chapters on Surgery in the Topics, Yellow Fever, Systemic Mycoses, and COVID-19. - Covers key topics such as drug resistance; emerging and reemerging infections such as Zika, Ebola, and Chikungunya; novel diagnostics such as PCR-based methods; point-of care-tests such as ultrasound; public health in settings of conflict and political instability; and much more. - Differentiates approaches for resource-rich and resource-poor areas. - Includes reader-friendly features such as highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams.
In honor of the bicentennial of Abraham Lincoln's birth comes this sequel to the enormously successful "Lincoln: An Illustrated Biography." This work picks up where the previous book left off, and examines how the 16th president's legend came into being.
The 3rd edition has been extensively re-written and many topics of particular interest to food technologists have been added or completely revised. The book now comprises more than 620 tables and 472 figures, including the structural formulae of around 1,100 food components. This standard text and reference is logically organized according to food constituents and commodities. It provides students and researchers in food science, food technology, agricultural chemistry and nutrition with the up-to-date information they require. The extensive tables for easy reference, the wealth of information, and the comprehensive subject index aid advanced students to acquire in-depth insight into food chemistry and technology and make this book also a valuable on-the-job reference for chemists, food chemists, food technologists, and more. Praise for the first edition: "Few books on food chemistry treat the subject as exhaustively researchers will find it to be a useful source of information. It is easy to read and the material is systematically presented." (JACS)
From the difficult to diagnose to the difficult to treat, Manson's Tropical Diseases prepares you to effectively handle whatever your patients may have contracted. Featuring an internationally recognized editorial team, global contributors, and expert authors, this revised and updated medical reference book provides you with the latest coverage on parasitic and infectious diseases from around the world. - Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. - Incorporate the latest therapies into your practice, such as recently approved drugs and new treatment options. - Find what you need easily and apply it quickly with highlighted key information, convenient boxes and tables, extensive cross-referencing, and clinical management diagrams. - Make the most accurate Tropical Disease diagnoses through a completely redesigned and modernized format, which includes full-color images throughout plus a wealth of additional illustrations online at Expert Consult. - Apply the latest treatment strategies for HIV/AIDS, tropical neurology, malaria, and much more. - Put the latest international expertise to work for you and your patients with new chapters covering Global Health; Global Health Governance and Tropical Diseases; Non-communicable Diseases; Obesity in the Tropics; and Emergency and Intensive Care Medicine in Resource-poor Settings. - See which diseases are most prevalent in specific areas of the tropics through a new index of diseases by country, as well as online-only maps that provide additional detail. - Better understand the variations in treatment approaches across the globe.
How can our societies be stabilized in a crisis? Why can we enjoy and understand Shakespeare? Why are fruitflies uniform? How do omnivorous eating habits aid our survival? What makes the Mona Lisa’s smile beautiful? How do women keep our social structures intact? – Could there possibly be a single answer to all these questions? This book shows that the statement: "weak links stabilize complex systems" provides the key to understanding each of these intriguing puzzles, and many more besides. The author, a recipient of several distinguished science communication prizes, explains weak or low probability interactions, and uses them as connecting threads in a vast variety of networks from proteins to ecosystems. This unique book and the ideas it develops will have a significant impact on diverse, seemingly unrelated fields of study.
This handbook will assist the practitioner, whether lawyer, counsel or arbitrator, in some of the practical minefields of international commercial arbitration. It considers the typical course of an international commercial arbitral proceeding, from deciding what claims may be arbitrated to calculating damages and the contents of an award, giving guidance and sample documents for each step. It also provides an extensive discussion of discovery and the presentation of evidence during hearings. This will work in aid the efficiency of the arbitral process, especially by reducing time and cost. For counsel and arbitrators alike, it provides a convenient reference work for the problems that inevitably arise in the procedural and substantive steps in arbitration. Analyzing the relevant law and rules from a range of jurisdictions and international arbitral institutions, the Handbook is a truly invaluable companion for everyone involved in international commercial arbitration.
Phospholipase A2 in Clinical Inflammation presents an up-to-date topical review of the biochemistry, molecular biology, and biology of mammalian phospholipase A2 (PLA2). The emphasis of this monograph is on the current aspects of PLA2 research using molecular approaches to investigate PLA2 structure and function, inhibitor design, and the regulation of sPLA2 and cPLA2 in cellular systems. The second section examines the major disease states where PLA2 has been implicated: rheumatoid diseases; acute pancreatitis; and psoriasis. These chapters, contributed by experts in the field, give the reader an overall sense of the clinical relevance of the molecular approaches to study PLA2 in relation to the disease entities that may be associated with altered PLA2 levels and activity. This comprehensive text not only provides the necessary historical review for beginning researchers but also addresses the more current molecular approaches as well as the major disease states for the seasoned researcher.
The HLA FactsBook presents up-to-date and comprehensive information on the HLA genes in a manner that is accessible to both beginner and expert alike. The focus of the book is on the polymorphic HLA genes (HLA-A, B, C, DP, DQ, and DR) that are typed for in clinical HLA laboratories. Each gene has a dedicated section in which individual entries describe the structure, functions, and population distribution of groups of related allotypes. Fourteen introductory chapters provide a beginner's guide to the basic structure, function, and genetics of the HLA genes, as well as to the nomenclature and methods used for HLA typing. This book will be an invaluable reference for researchers studying the human immune response, for clinicians and laboratory personnel involved in clinical and forensic HLA typing, and for human geneticists, population biologists, and evolutionary biologists interested in HLA genes as markers of human diversity. Introductory chapters provide good general overview of HLA field for novice immunologists and geneticists Up-to-date, complete listing of HLA alleles Invaluable reference resource for immunologists, geneticists, and cell biologists Combines both structural and functional information, which has never been compiled in a single reference book previously Serological specificity of allotypes Identity of material sequenced including ethnic origin Database accession numbers Population distribution Peptide binding specificities T cell epitopes Amino acid sequences of allotypes Key references
This book introduces and analyzes the crucial role of AP-1 in cell growth, proliferation, differentiation, and apoptosis. AP-1 is the endpoint of several pathways of signal transduction, including one that triggers cancerous growth. The control of its activity is an issue of basic science, cancer therapy, and other diseases. The chapters provide multiple viewpoints of the emerging data on AP-1, including its role as a factor regulating genes involved in the metastatic properties of cancer, as a factor that interacts with viral gene products, and as a part of the mechanism by which steroid and retinoic acid receptors function as anti-inflammatory proteins.
New edition of the acclaimed organic chemistry text that brings exceptional clarity and coherence to the course by focusing on the relationship between structure and function.
Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes, coacervates, ion-exchange resins, and liposomes, as well as non-particulate vehicles such as enteric coatings, mediators, and bioadhesives. Other topics discussed include diffusion; biodegradation-controlled delivery; animal model studies for toxicity, metabolism, and elimination testing; and FDA requirements for clinical studies. Drug delivery researchers will find this book to be an invaluable reference tool.
The ideas, people, and events that developed art education are described and analyzed so that art educators and educators in general will have a better understanding of what has happened (and is happening) to visual art in the schools. Peter Smith raises the issue of art education's inordinate emphasis on Eurocentric art. He challenges the often expressed notion that the field of education is the cause of art education's problems and proposes that confused conceptions within the art world are just as much a root of the difficulty. No other book in art education history gives such close and analytical attention to the careers of women in the field. The materials on Germanic cultural and historical influences are unequaled as is the scholarly treatment of Viktor Lowenfeld, probably the most influential single figure in 20th-century American art education.
Preclinical and Clinical Modulation of Anticancer Drugs focuses on the theoretical and practical approaches to designing and enacting modulation principles. Each class of anticancer drug and the different types of modulators used within each drug class are discussed within individual chapters. The molecular and biochemical rationale for the use of specific modulators is discussed in detail, and preclinical and clinical implications of the data are integrated into each chapter. Mechanisms of drug resistance and the reasons behind circumventing the resistant phenotype are covered. The book will interest cancer chemotherapists, pharmacologists, oncologists, biochemists, and experimental therapeutics researchers, in addition to students studying the principles of drug discovery and protocol design.
Birkhäuser's Pocket Dictionary of Biochemistry is the most comprehensive English-German/German-English dictionary on the international market. More than 30.000 entries and subentries with some 50.000 translations and an extent appendix with a specifically compiled list of abbreviations provide users with an unrivaled coverage of biochemistry and related bioscientific areas. The dictionary excels through a harmonious synthesis of biochemical and general bilingual dictionaries, making it the ideal choice for users from both scientific and linguistic fields. Furthermore Birkhäuser's Pocket Dictionary of Biochemistry is marked by a first class linguistic and lexicographic treatment achieving a very high user friendliness and user satisfaction. In the English-German part British terms have been included in addition to American terms, thus making it possible to find entries from either language.
For those with legitimate reason to use the Internet anonymously--diplomats, military and other government agencies, journalists, political activists, IT professionals, law enforcement personnel, political refugees and others--anonymous networking provides an invaluable tool, and many good reasons that anonymity can serve a very important purpose. Anonymous use of the Internet is made difficult by the many websites that know everything about us, by the cookies and ad networks, IP-logging ISPs, even nosy officials may get involved. It is no longer possible to turn off browser cookies to be left alone in your online life. Practical Anonymity: Hiding in Plain Sight Online shows you how to use the most effective and widely-used anonymity tools--the ones that protect diplomats, military and other government agencies to become invisible online. This practical guide skips the theoretical and technical details and focuses on getting from zero to anonymous as fast as possible. For many, using any of the open-source, peer-reviewed tools for connecting to the Internet via an anonymous network may be (or seem to be) too difficult because most of the information about these tools is burdened with discussions of how they work and how to maximize security. Even tech-savvy users may find the burden too great--but actually using the tools can be pretty simple. The primary market for this book consists of IT professionals who need/want tools for anonymity to test/work around corporate firewalls and router filtering as well as provide anonymity tools to their customers. Simple, step-by-step instructions for configuring and using anonymous networking software - Simple, step-by-step instructions for configuring and using anonymous networking software - Use of open source, time-proven and peer-reviewed tools for anonymity - Plain-language discussion of actual threats and concrete suggestions for appropriate responses - Easy-to-follow tips for safer computing - Simple, step-by-step instructions for configuring and using anonymous networking software - Use of open source, time-proven and peer-reviewed tools for anonymity - Plain-language discussion of actual threats, and concrete suggestions for appropriate responses - Easy to follow tips for safer computing
More information is always better, and full information is best. More computation is always better, and optimization is best." More-is-better ideals such as these have long shaped our vision of rationality. Yet humans and other animals typically rely on simple heuristics to solve adaptive problems, focusing on one or a few important cues and ignoring the rest, and shortcutting computation rather than striving for as much as possible. In this book, we argue that in an uncertain world, more information and computation are not always better, and we ask when, and why, less can be more. The answers to these questions constitute the idea of ecological rationality: how we are able to achieve intelligence in the world by using simple heuristics matched to the environments we face, exploiting the structures inherent in our physical, biological, social, and cultural surroundings.
The 21st century is on the verge of a possible total economic and political revolution. Technological advances in robotics, computing and digital communications have the potential to completely transform how people live and work. Even more radically, humans will soon be interacting with artificial intelligence (A.I.) as a normal and essential part of their daily existence. What is needed now more than ever is to rethink social relations to meet the challenges of this soon-to-arrive "smart" world. This book proposes an original theory of trans-human relations for this coming future. Drawing on insights from organisational studies, critical theory, psychology and futurism - it will chart for readers the coming changes to identity, institutions and governance in a world populated by intelligent human and non-human actors alike. It will be characterised by a fresh emphasis on infusing programming with values of social justice, protecting the rights and views of all forms of "consciousness" and creating the structures and practices necessary for encouraging a culture of "mutual intelligent design". To do so means moving beyond our anthropocentric worldview of today and expanding our assumptions about the state of tomorrow's politics, institutions, laws and even everyday existence. Critically such a profound shift demands transcending humanist paradigms of a world created for and by humans and instead opening ourselves to a new reality where non-human intelligence and cyborgs are increasingly central.
The production of this book represents a culmination for me of some 25 years of interest in the field of personality and substance use and abuse. In choosing the field of substanceuse and abuse for the focus of our research, all of the investi- tors collaborating in this research have been sustained by the awareness that the work we are doing has an important purpose. Substance abuse continues to have enormous impacts on individuals and families,and prevention and treatment - proaches developed to date have not always been as successful as we would hope to see. New advances in our fundamental understanding of the causal mec- nisms involved in the development ofaddiction may be necessary to advance our success in developing new forms of prevention and treatment for alcohol and drug abuse. The work in this book builds on the work of numerous previous investi- tors who have been drawn to investigate this topic. As you will notice in the extensive reference list, there have been hundreds of articles published on this topic. Although each of these references has added a small piece to our und- standing of the relationship between personality and alcohol abuse, the majority of these studies have been done on clinical samples and often involved no control groups or poorly matched control groups. Several important previous longitu- nal investigations have been conducted,but these investigations have usually not included general population samples or comprehensivepersonality test batteries.
The goal of How to Make Maps is to equip readers with the foundational knowledge of concepts they need to conceive, design, and produce maps in a legible, clear, and coherent manner, drawing from both classical and modern theory in cartography. This book is appropriate for graduate and undergraduate students who are beginning a course of study in geospatial sciences or who wish to begin producing their own maps. While the book assumes no a priori knowledge or experience with geospatial software, it may also serve GIS analysts and technicians who wish to explore the principles of cartographic design. The first part of the book explores the key decisions behind every map, with the aim of providing the reader with a solid foundation in fundamental cartography concepts. Chapters 1 through 3 review foundational mapping concepts and some of the decisions that are a part of every map. This is followed by a discussion of the guiding principles of cartographic design in Chapter 4—how to start thinking about putting a map together in an effective and legible form. Chapter 5 covers map projections, the process of converting the curved earth’s surface into a flat representation appropriate for mapping. Chapters 6 and 7 discuss the use of text and color, respectively. Chapter 8 reviews trends in modern cartography to summarize some of the ways the discipline is changing due to new forms of cartographic media that include 3D representations, animated cartography, and mobile cartography. Chapter 9 provides a literature review of the scholarship in cartography. The final component of the book shifts to applied, technical concepts important to cartographic production, covering data quality concepts and the acquisition of geospatial data sources (Chapter 10), and an overview of software applications particularly relevant to modern cartography production: GIS and graphics software (Chapter 11). Chapter 12 concludes the book with examples of real-world cartography projects, discussing the planning, data collection, and design process that lead to the final map products. This book aspires to introduce readers to the foundational concepts—both theoretical and applied—they need to start the actual work of making maps. The accompanying website offers hands-on exercises to guide readers through the production of a map—from conception through to the final version—as well as PowerPoint slides that accompany the text.
The ability to successfully clone genes underlies the majority of our knowledge in molecular and cellular biology. Gene Cloning introduces the diverse array of techniques available to clone genes and how they can be used effectively both in the research laboratory, to gain knowledge about the gene, and for use in biotechnology, medicine, the pharmaceutical industry, and agriculture. It shows how cloning genes is an integral part of genomics and underlines its relevance in the post-genomic age, as a tool required to test predictions of gene regulation and function made through bioinformatics. Applications of gene cloning in medicine, both for diagnosis and treatment, and in the pharmaceutical industry and agriculture, are also covered in the book. Gene Cloning takes a fresh approach to teaching molecular and cellular biology and will be a valuable resource to both undergraduates and lecturers of biological and biomedical science courses.
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Worldwide, the numbers of people suffering and dying from parasitic diseases are overwhelming, with more than 100 million cases and 1 million deaths each year from malaria alone. Despite the magnitude of the problem and the importance of the parasites that cause opportunistic infections among persons with HIV/AIDS, medical schools in the United States, Canada, and other developed countries consistently reduce the amount of time spent on parasitic diseases in the curricu lum. As a result most medical students receive limited information about these diseases, and are inadequately prepared to diagnose or treat them as physicians. This problem is too large to be resolved within the time available for parasitology in the medical school curriculum; at most, students can be acquainted with the salient features of the medically important parasites. Likewise, the traditional isolation of parasitology from the rest of the curriculum (consistent with its exclu sion from most microbiology texts) is another unresolved problem. In my opinion, this is why most physicians are unable to think about the differential diagnosis of parasitic diseases in the same way that they routinely balance the probabilities of malignancy, cardiovascular, renal, and pulmonary disease vs other infectious diseases. To resolve these problems, relevant paradigms from parasitology must be used in the teaching of cell biology, molecular biology, genetics, and immu nology.
Murphy on Evidence frames the law in its practical context. Suitable for both undergraduates and BPTC students, the text is supported by a wealth of online resources based around two fictional cases, bringing the law to life, and developing a clear contextual understanding of the subject.
A unique and outstanding military and industrial achievement, the Collins class submarine project was also plagued with difficulties and mired in politics. Its story is one of heroes and villains, grand passions, intrigue, lies, spies and backstabbing. It is as well a story of enormous commitment and resolve to achieve what many thought impossible. The building of these submarines was Australia's largest, most expensive and most controversial military project. From initiation in the 1981–2 budget to the delivery of the last submarine in 2003, the total cost was in excess of six billion dollars. Over 130 key players were interviewed for this book, and the Australian Defence Department allowed access to its classified archives and the Australian Navy archives. Vividly illustrated with photographs from the collections of the Royal Australian Navy and ASC Pty Ltd, The Collins Class Submarine Story: Steel, Spies and Spin, first published in 2008, is a riveting and accessibly written chronicle of a grand-scale quest for excellence.
First Published in 1988, this book documents the role, biology, and structure of the Intervertebral Disc. Carefully compiled and filled with a vast repertoire of notes, diagrams, and references this book serves as a useful reference for Students of Medicine, Chiropractors, and other practitioners in their respective fields.
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