Peter Csermely's Books

Weak Links

The Universal Key to the Stability of Networks and Complex Systems

By: Peter Csermely

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Weak Links

The Universal Key to the Stability of Networks and Complex Systems

By: Peter Csermely

How can our societies be stabilized in a crisis? Why can we enjoy and understand Shakespeare? Why are fruitflies uniform? How do omnivorous eating habits aid our survival? What makes the Mona Lisa’s smile beautiful? How do women keep our social structures intact? – Could there possibly be a single answer to all these questions? This book shows that the statement: "weak links stabilize complex systems" provides the key to understanding each of these intriguing puzzles, and many more besides. The author, a recipient of several distinguished science communication prizes, explains weak or low probability interactions, and uses them as connecting threads in a vast variety of networks from proteins to ecosystems. This unique book and the ideas it develops will have a significant impact on diverse, seemingly unrelated fields of study.

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422

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3540311572

ISBN 13

9783540311577

Structure and Function of Intrinsically Disordered Proteins

By: Peter Tompa,Alan Fersht

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Structure and Function of Intrinsically Disordered Proteins

By: Peter Tompa,Alan Fersht

The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug dev

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Page Count

362

Publisher

CRC Press

Published Date

ISBN 10

1420078933

ISBN 13

9781420078930

Weak Links

The Universal Key to the Stability of Networks and Complex Systems

By: Peter Csermely

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Weak Links

The Universal Key to the Stability of Networks and Complex Systems

By: Peter Csermely

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422

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Springer Science & Business Media

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ISBN 10

3540311572

ISBN 13

9783540311577

Recent Advances in Plant Biotechnology

By: Ara Kirakosyan,Peter B. Kaufman

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Recent Advances in Plant Biotechnology

By: Ara Kirakosyan,Peter B. Kaufman

Plant biotechnology applies to three major areas of plants and their uses: (1) control of plant growth and development; (2) protection of plants against biotic and abiotic stresses; and (3) expansion of ways by which specialty foods, biochemicals, and pharmaceuticals are produced. The topic of recent advances in plant biotechnology is ripe for consideration because of the rapid developments in this ?eld that have revolutionized our concepts of sustainable food production, cost-effective alt- native energy strategies, environmental bioremediation, and production of pla- derived medicines through plant cell biotechnology. Many of the more traditional approaches to plant biotechnology are woefully out of date and even obsolete. Fresh approaches are therefore required. To this end, we have brought together a group of contributors who address the most recent advances in plant biotechnology and what they mean for human progress, and hopefully, a more sustainable future. Achievements today in plant biotechnology have already surpassed all previous expectations. These are based on promising accomplishments in the last several decades and the fact that plant biotechnology has emerged as an exciting area of research by creating unprecedented opportunities for the manipulation of biological systems. In connection with its recent advances, plant biotechnology now allows for the transfer of a greater variety of genetic information in a more precise, controlled manner. The potential for improving plant productivity and its proper use in agric- ture relies largely on newly developed DNA biotechnology and molecular markers.

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Page Count

408

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1441901949

ISBN 13

9781441901941

The Molecular Basis of Cancer E-Book

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

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The Molecular Basis of Cancer E-Book

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

2015 BMA Medical Book Awards Highly Commended in Oncology Category!The Molecular Basis of Cancer arms you with the latest knowledge and cutting-edge advances in the battle against cancer. This thoroughly revised, comprehensive oncology reference explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease. A team of leading experts thoroughly explains the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Detailed descriptions of topics from molecular abnormalities in common cancers to new approaches for cancer therapy equip you to understand and apply the complexities of ongoing research in everyday clinical application. - Effectively determine the course of malignancy and design appropriate treatment protocols by understanding the scientific underpinnings of cancer. - Visually grasp and retain difficult concepts easily thanks to a user-friendly format with abundant full-color figures. - Find critical information quickly with chapters following a logical sequence that moves from pathogenesis to therapy. - Stay current with the latest discoveries in molecular and genomic research. Sweeping revisions throughout include eight brand-new chapters on: Tumor Suppressor Genes; Inflammation and Cancer; Cancer Systems Biology: The Future; Biomarkers Assessing Risk of Cancer; Understanding and Using Information About Cancer Genomes; The Technology of Analyzing Nucleic Acids in Cancer; Molecular Abnormalities in Kidney Cancer; and Molecular Pathology. - Access the entire text and illustrations online, fully searchable, at Expert Consult.

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Page Count

1040

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323261965

ISBN 13

9780323261968

The Hsp60 Chaperonin

By: Peter Bross

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The Hsp60 Chaperonin

By: Peter Bross

In this unique overview of the Hsp60 chaperonin, Peter Bross addresses molecular biologists, medical research scientists and individuals interested in molecular or general biology. First, Bross discusses the basics of the Hsp60 chaperonin in terms of its structure and the molecular mechanisms determining its function. Second, the author highlights the multiple roles of Hsp60 for cellular systems and regulatory pathways, especially in connection with neurodegenerative diseases caused by Hsp60 deficiency. Finally, the author highlights controversial observations suggesting additional, non-standard functions of Hsp60 in and outside mitochondria as well as possible gaps in our understanding of the chaperonin. This volume serves as a snapshot suitable for experienced researcher working in fields related to molecular chaperones yet still accessible to researchers entering the field.

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Springer

Published Date

ISBN 10

331926088X

ISBN 13

9783319260884

The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

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The Molecular Basis of Cancer

Expert Consult - Online

By: John Mendelsohn,Peter M. Howley,Mark A. Israel,Joe W. Gray,Craig B. Thompson

Successfully fighting cancer starts with understanding how it begins. This thoroughly revised 3rd Edition explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of cancer. A team of leading experts thoroughly explain the molecular biologic principles that underlie the diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating cutting-edge advances and the newest research, the book provides thorough descriptions of everything from molecular abnormalities in common cancers to new approaches for cancer therapy. Features sweeping updates throughout, including molecular targets for the development of anti-cancer drugs, gene therapy, and vaccines...keeping you on the cutting edge of your specialty. Offers a new, more user-friendly full-color format so the information that you need is easier to find. Presents abundant figures-all redrawn in full color-illustrating major concepts for easier comprehension. Features numerous descriptions of the latest clinical strategies-helping you to understand and take advantage of today’s state-of-the-art biotechnology advances.

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Page Count

1948

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437710999

ISBN 13

9781437710991

Quantitative Understanding of Biosystems

An Introduction to Biophysics, Second Edition

By: Thomas M. Nordlund,Peter M. Hoffmann

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Quantitative Understanding of Biosystems

An Introduction to Biophysics, Second Edition

By: Thomas M. Nordlund,Peter M. Hoffmann

Praise for the prior edition "The author has done a magnificent job... this book is highly recommended for introducing biophysics to the motivated and curious undergraduate student." ―Contemporary Physics "a terrific text ... will enable students to understand the significance of biological parameters through quantitative examples―a modern way of learning biophysics." ―American Journal of Physics "A superb pedagogical textbook... Full-color illustrations aid students in their understanding" ―Midwest Book Review This new edition provides a complete update to the most accessible yet thorough introduction to the physical and quantitative aspects of biological systems and processes involving macromolecules, subcellular structures, and whole cells. It includes two brand new chapters covering experimental techniques, especially atomic force microscopy, complementing the updated coverage of mathematical and computational tools. The authors have also incorporated additions to the multimedia component of video clips and animations, as well as interactive diagrams and graphs. Key Features: Illustrates biological examples with estimates and calculations of biophysical parameters. Features two brand-new chapters on experimental methods, a general overview and focused introduction to atomic force microscopy. Includes new coverage of important topics such as measures of DNA twist, images of nanoparticle assembly, and novel optical and electron nanoscopy. Provides a guide to investigating current expert biophysical research. Enhanced self-study problems and an updated glossary of terms.

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Page Count

608

Publisher

CRC Press

Published Date

ISBN 10

135180118X

ISBN 13

9781351801188

Computational Methods for Understanding Bacterial and Archaeal Genomes

By: Ying Xu,J. Peter Gogarten

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Computational Methods for Understanding Bacterial and Archaeal Genomes

By: Ying Xu,J. Peter Gogarten

Over 500 prokaryotic genomes have been sequenced to date, and thousands more have been planned for the next few years. While these genomic sequence data provide unprecedented opportunities for biologists to study the world of prokaryotes, they also raise extremely challenging issues such as how to decode the rich information encoded in these genomes. This comprehensive volume includes a collection of cohesively written chapters on prokaryotic genomes, their organization and evolution, the information they encode, and the computational approaches needed to derive such information. A comparative view of bacterial and archaeal genomes, and how information is encoded differently in them, is also presented. Combining theoretical discussions and computational techniques, the book serves as a valuable introductory textbook for graduate-level microbial genomics and informatics courses.

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Page Count

494

Publisher

World Scientific

Published Date

ISBN 10

1860949827

ISBN 13

9781860949821

Raman Spectroscopy in Cultural Heritage Preservation

By: Howell G. M. Edwards,Peter Vandenabeele,Philippe Colomban

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Raman Spectroscopy in Cultural Heritage Preservation

By: Howell G. M. Edwards,Peter Vandenabeele,Philippe Colomban

This book addresses the application of Raman spectroscopic techniques to a range of diverse problems which arise in the study, conservation and restoration of artefacts and sites closely related to our cultural heritage as well as in authentication. These themes are naturally wider than what at first might be considered as artworks and archaeological artefacts and the topics include pigments, paintings, ceramics, glass, sculpture and patination / corrosion, textiles, industrial archaeology, the degradation and preservation of biomaterials, mummies and human skeletal remains. An interesting feature is the inclusion of modern case studies which describe specific problems and approaches to the Raman spectral analysis of items important to our cultural heritage. The text is prefaced with an introduction to the important parameters used in nondestructive Raman measurements and also highlights some future applications based upon novel miniaturised instrumentation for in-field studies and potential screening work which will identify specimens which would repay further studies in the laboratory. An attempt is made to give a snapshot of the state-of-the-art evolution since the beginning of the technique (1970s) and to point out potential further development. The book is co-edited by three international experts with many years' experience in the application of Raman spectroscopy to artworks, archaeological artefacts and in the investigation of materials and sites for cultural heritage preservation and each editor has undertaken to write individual chapters and different topics personally. The adopted approach is designed to convey the sort of information which has become available from the adoption of analytical Raman spectroscopy to different problems in the field of cultural heritage preservation through the spectral interrogation of artefacts and how the interpretation of the spectral data can assist museum curators, archaeologists and cultural heritage historians in the preservation and conservation of ancient materials and sites : a particular advantage in this respect is the ability of Raman spectroscopy to determine –generally in a strictly noninvasive procedure - at the laboratory or on-site with mobile instruments, the presence of both organic and inorganic components in a particular specimen together nondestructively without any chemical and mechanical pretreatment being undertaken, which is an essential requirement for rare and valuable samples . An important aside from this work is the means of spectral identification of ongoing biodeterioration and biological colonisation in specimens in storage and the effects of environmental deterioration such as humidity and temperature upon their integrity.

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Page Count

520

Publisher

Springer Nature

Published Date

ISBN 10

3031143795

ISBN 13

9783031143793

Actin

By: Peter Sheterline,Jon Clayton,John C. Sparrow

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Actin

By: Peter Sheterline,Jon Clayton,John C. Sparrow

Actins are a highly conserved family of proteins found in virtually all eukaryotic cells. They have prolific roles in cell motility - from the contraction of striated muscle to the movement of organelles within cells, and are known to interact with a diverse number of proteins families from myosins to gelsolins. This up-to-date edition gives a comprehensive account of actin sequence, mutation and structure as well as providing insight into ligand-binding sites and drug and toxin binding. Illustrated throughout, this modern text also contains an extensive bibliography for the interested reader.

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Page Count

293

Publisher

OUP Oxford

Published Date

ISBN 10

0191589934

ISBN 13

9780191589935

Neural Organization

Structure, Function, and Dynamics

By: Michael A. Arbib,Peter Erdi,Alice Szentagothai

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Neural Organization

Structure, Function, and Dynamics

By: Michael A. Arbib,Peter Erdi,Alice Szentagothai

In Neural Organization, Arbib, Érdi, and Szentágothai integrate structural, functional, and dynamical approaches to the interaction of brain models and neurobiologcal experiments. In Neural Organization, Arbib, Érdi, and Szentágothai integrate structural, functional, and dynamical approaches to the interaction of brain models and neurobiologcal experiments. Both structure-based "bottom-up" and function- based "top-down" models offer coherent concepts by which to evaluate the experimental data. The goal of this book is to point out the advantages of a multidisciplinary, multistrategied approach to the brain. Part I of Neural Organization provides a detailed introduction to each of the three areas of structure, function, and dynamics. Structure refers to the anatomical aspects of the brain and the relations between different brain regions. Function refers to skills and behaviors, which are explained by means of functional schemas and biologically based neural networks. Dynamics refers to the use of a mathematical framework to analyze the temporal change of neural activities and synaptic connectivities that underlie brain development and plasticity—in terms of both detailed single-cell models and large-scale network models. In part II, the authors show how their systematic approach can be used to analyze specific parts of the nervous system—the olfactory system, hippocampus, thalamus, cerebral cortex, cerebellum, and basal ganglia—as well as to integrate data from the study of brain regions, functional models, and the dynamics of neural networks. In conclusion, they offer a plan for the use of their methods in the development of cognitive neuroscience.

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Page Count

421

Publisher

MIT Press

Published Date

ISBN 10

0262526417

ISBN 13

9780262526418

Book's by Peter Csermely

Weak Links

Weak Links

Structure and Function of Intrinsically Disordered Proteins

Structure and Function of Intrinsically Disordered Proteins

Weak Links

Weak Links

Recent Advances in Plant Biotechnology

Recent Advances in Plant Biotechnology

The Molecular Basis of Cancer E-Book

The Molecular Basis of Cancer E-Book

The Hsp60 Chaperonin

The Hsp60 Chaperonin

The Molecular Basis of Cancer

The Molecular Basis of Cancer

Quantitative Understanding of Biosystems

Quantitative Understanding of Biosystems

Computational Methods for Understanding Bacterial and Archaeal Genomes

Computational Methods for Understanding Bacterial and Archaeal Genomes

Raman Spectroscopy in Cultural Heritage Preservation

Raman Spectroscopy in Cultural Heritage Preservation

Actin

Actin

Neural Organization

Neural Organization

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