Hypermobility of Joints 4th Edition follows the same format as its successful predecessors. The aim of which was to provide an overview of hyperlaxity of joints and this edition follows that aim by describing the most recent research and new developments in biochemistry, as well as providing practical advice on clinical features and management. Hypermobility of Joints 4th Edition provides illustrative case histories, a review of hypermobility in the performing arts and sports and an outline of heritable hypermobility syndromes. This book is a valuable reference tool for a wide number of specialties, although it will particularly be of interest to rheumatologists, orthopedic surgeons and medical geneticists.
The Man Behind the Syndrome by my friends and colleagues Peter and Greta Beighton is a delightful book which will be read eagedy and with keen intellectual pleasure by all human, medical, and dinical genetieists. The reader with a historical tum of mind will note right away that the book achieyes more than the usual entry in a dictionary of seientific biography. In addition to the standard professional data, it gives a photo and some personal glimpses of the man, allowing the reader to appreeiate his human qualities as weIl. This volume contains, so to speak, the creme de la creme, namely, those in a group whose names are daily on the lips of every practicing dinical geneticist. This interesting and instructive book is commended to all in medical genetics and the history of medieine with the highest enthusiasm and gratitude to its authors for undertaking this labor of love. A second volume is planned for more recently delineated disorders for which an eponym is not yet widely used.
Fully updated to meet the demands of the 21st-century surgeon, Plastic Surgery provides you with all the most current knowledge and techniques across your entire field, allowing you to offer every patient the best possible outcome. Edited by Drs. Mathes and Hentz in its last edition, this six-volume plastic surgery reference now features new expert leadership, a new organization, new online features, and a vast collection of new information - delivering all the state-of-the-art know-how you need to overcome any challenge you may face. Renowned authorities provide evidence-based guidance to help you make the best clinical decisions, get the best results from each procedure, avoid complications, and exceed your patients’ expectations. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Apply the very latest advances in every area of plastic surgery and ensure optimal outcomes with evidence-based advice from a diverse collection of world-leading authorities. Master the latest on stem cell therapy, tissue engineering, and inductive therapies • aesthetic surgical techniques and nonsurgical treatments • conjoined twin separation and other craniofacial surgery advances • microsurgical lymphatic reconstruction, super microsurgery, and sternal fixation • autologous lipofilling of the breast • nerve transfers in hand surgery, hand allotransplantation, and functional prosthetics • and much, much more. Easily find the answers you need with a new organization that features separate volumes covering Principles • Aesthetic • Craniofacial, Head and Neck Surgery • Lower Extremity, Trunk and Burns • Breast • and Hand and Upper Extremity, plus a more templated, user-friendly, high-yield presentation. Visualize procedures more clearly through an abundance of completely redrawn full-color illustrations and new color clinical photographs. Access the complete, fully searchable contents of each volume online, download all the tables and figures, view 160 procedural videos, and take advantage of additional content and images at www.expertconsult.com!
Through a study of horses, the book reveals how an important and growing aristocratic estate was managed, where the aristocrat at the centre of it - William Cavendish - travelled and how he spent his time, and how horses were oneof the means by which he asserted his social status.
A decade after the publication of The Man Behind the Syndrome, which was warmly received, particularly by medical geneticists, syndromologists and those doctors from many different dis ciplines with an interest in medical history, Peter and Greta Beighton now present the second volume of their work, promised ten years ago. The length of time which has passed since the pub lication of the first book gives an inkling of the extraordinary effort involved on the part of the authors in collecting the necessary biographical data and the portraits of their subjects. The Person Behind the Syndrome conforms exactly in structure, quality and size with the first volume, thus facilitating the use of the series. Again we find detailed presentations of a hundred people who have given their names to disorders or syndromes which are thought to have a significant genetic or chromosomal component (with a photograph or portrait, biography, com mentary on the development of nomenclature and references). The reader finds information not only on the doctor and/or scientist under discussion, but also, as in the previous volume, on the person behind the name. This is followed by brief, un illustrated biographies of about seventy, mostly younger and, in some cases, still professionally active personalities.
The #1 text in Sports Medicine! This cornerstone textbook has been updated with the latest research and developments. Brukner & Khan's world-leading title provides an authoritative foundation for clinicians and students. This complete practical guide to physiotherapy and musculoskeletal medicine covers all aspects of diagnosis and contemporary management of sports-related injuries. The fifth edition has been expanded to accommodate a much higher level of evidence-based content and reflects the huge amount of new research and significant changes in thinking since the previous edition was published. The contributing editors are an international compilation of globally recognised experts within their fields. This is essential reading for sports medicine physicians, physical therapists and physical therapy students. Topics in Volume Two Include: •Exercise and health •Exercise and disease •Environment •Harassment and abuse •Special groups •Maximising athletic performance •Nutrition for performance
The essential guide to living with orthostatic intolerance. Orthostatic intolerance (OI) describes a group of circulatory disorders whose symptoms are characterized by a dramatic drop in blood flow to the brain when people sit down or stand up. It is often associated with other acute issues, such as substantial drops in blood pressure, tachycardia, dizziness, and fainting, or long-term problems, such as chronic fatigue, fibromyalgia, and "long COVID." Living Well with Orthostatic Intolerance is an indispensable guide for those diagnosed with the disorder, their families, and physicians. Written by Peter C. Rowe, MD, a pediatrician, researcher, and professor who directs the Chronic Fatigue Clinic at Johns Hopkins Children's Center, this guide explains: • The symptoms, causes, and different forms of OI • What a diagnosis of OI entails • How to manage OI symptoms using medications, physical therapy, and other treatments • How diet affects OI Guided by decades of research on managing and treating OI patients, Dr. Rowe provides illustrative case studies to help explain the disease and includes additional resources for further information.
Kim is a good typist. When her new boss dictates the story of an old, bloody murder she must become clever, wise and brave. What she must avoid are nausea, stupidity, obsession... and sleep.
This book provides a clear and concise guide to hypermobility in medicine and physiotherapy. Each chapter is written with a uniform style, including illustrations highlighting the clinical characteristics of manifestations related to hypermobility. Key topics are comprehensively covered throughout the book in the context of both medicine and physiotherapy. This book offers supportive information for practitioners who are seeking as single resource on the topic. Medical professionals, physiotherapists, physical educators, psychologists, nutritionists, occupational therapists, psychomotor therapists, and postgraduate students will find this book to be an essential guide in their daily clinical practice and research in the field.
When 1 first developed an interest in the pathology of bone 1 found that there were relatively few books on the subject available. Much of my information had either to be obtained from searching the journals or from senior colleagues in the field, who, 1 should add, were always more than willing to teach me. With this memory in mind, 1 have endeavoured to produce a book which 1 hope is of a convenient size and yet will hold sufficient information to be of use mainly to the pathologist faced with a bone problem. This is not intended to be an all-embracing source of knowledge on the subject; indeed, such a task could not be undertaken by a single author in these days of the rapid increase in information even in small subspecialist areas within bone pathology. Although this book is written mainly for the pathologist, it is hoped that it may also be of interest and value to orthopaedic surgeons, rheumatolog ists and radiologists. Most of the illustrations are original and many of the drawings are my own. There has been a long tradition of interest in bone pathology at The London Hospital, which has resulted in a wealth of material being available to me from the archives of the Department of Morbid Anatomy. A few of the photo graphs are those of Prof. H. Turnbull; the observant reader will detect these, since the scales used are not metric.
Make optimal use of the latest diagnostic and interventional ultrasound applications in your practice! This new edition of the world's best-selling reference on obstetric and gynecologic ultrasound guides you through all of the newest ultrasound technologies, enabling you to diagnose problems accurately. The entire book has been radically updated by many new contributors to reflect all of the most recent advances, including greatly expanded information on 3-D ultrasound and the latest generation of ultrasound scanners, as well as significantly increased discussions of gynecologic ultrasound. What's more, over 2,400 digital-quality images - 1,050 in full color - capture the characteristic appearance of a full range of ultrasound findings, and a new full-color format makes reference easier than ever. The result is an essential purchase for everyone who uses ultrasound for fetal and gynecologic diagnosis and treatment. Get dependable guidance on any clinical issue or challenge by consulting the world's most popular, trusted reference on ob/gyn ultrasound! Obtain optimal results by applying the masterful expertise of world-renowned authority Peter W. Callen, MD, as well as a care of other top specialists on the diagnostic and interventional applications of ultrasound. Make optimal use of all of the latest developments, including 3-D ultrasound, the use of the latest generation of ultrasound scanners, the growing role of ultrasound in gynecologic imaging. Diagnose with confidence by comparing your imaging findings to more than 2,400 digital-quality images - 1,050 in full color - that depict the complete range of normal and abnormal imaging presentations. Locate information more quickly thanks to a new highly templated, full-color format. Visualize key anatomic details more clearly with hundreds of medical illustrations redrawn in full color.
The V 1, or Doodlebug or Flying-bomb came into use in June 1944 and, together with the V 2 Rocket, was Hitlers final hope in face of the advancing Allied forces sweeping across Europe towards Germany. Of the 8,000 that were launched within the first 80 days, some 2,300 reached the London area where they caused more death and destruction to its population and buildings. As the front line moved eastwards, many of the ground-based launch ramps became denied to the German forces and the modest range of the missile meant that other means of launching must be considered to continue the threat. An air-launching system, utilizing the Luftwaffes Heinkel 111 bomber, was developed and operated by the newly formed Kampfgeschwader units. This posed a dramatic new threat to the UK because the V 1s effective range was considerably increased and its mobile firing point offered a much greater target area when fired from an aircraft flying over the North Sea. This is the story of the development and operation of this new form of attack and also of the Allied reaction and defense-measures taken to minimize damage.
An eminent geneticist, veteran author, OMMG Series Editor, and noted archivist, Peter Harper presents a lively account of how our ideas and knowledge about human genetics have developed over the past century from the perspective of someone inside the field with a deep interest in its historical aspects. Dr. Harper has researched the history of genetics and has had personal contact with a host of key figures whose memories and experiences extend back 50 years, and he has interviewed and recorded conversations with many of these important geneticists. Thus, rather than being a conventional history, this book transmits the essence of the ideas and the people involved and how they interacted in advancing- and sometimes retarding- the field. From the origins of human genetics; through the contributions of Darwin, Mendel, and other giants; the identification of the first human chromosome abnormalities; and up through the completion of the Human Genome project, this Short History is written in the author's characteristic clear and personal style, which appeals to geneticists and to all those interested in the story of human genetics.
In Island Epidemics, the authors show that the complex warfare of invasion and extinction observed by Darwin for plants and animals applies with equal force to human diseases. A world picture is presented of diseases, which range from the familiar (influenza and German measles) to the exotic (kuru and tsutsugamushi), and islands which range in remoteness, from the accessible United Kingdom to the inaccessible Tristan da Cunha and Easter Island.
Easy to use, and useful when kept close at hand in the room where you work. The book is a pleasure to read: the style elegant and authoritative.' Lancet'...this book is a wonderful reference to enable primary physicians to be informed about their patients.' Annals of Internal MedicineUniversally used across the world by genetic counsellors, medical
Offering unparalleled coverage of infectious diseases in children and adolescents, Feigin & Cherry's Textbook of Pediatric Infectious Diseases 8th Edition, continues to provide the information you need on epidemiology, public health, preventive medicine, clinical manifestations, diagnosis, treatment, and much more. This extensively revised edition by Drs. James Cherry, Gail J. Demmler-Harrison, Sheldon L. Kaplan, William J. Steinbach, and Peter J. Hotez, offers a brand-new full-color design, new color images, new guidelines, and new content, reflecting today's more aggressive infectious and resistant strains as well as emerging and re-emerging diseases - Discusses infectious diseases according to organ system, as well as individually by microorganisms, placing emphasis on the clinical manifestations that may be related to the organism causing the disease. - Provides detailed information regarding the best means to establish a diagnosis, explicit recommendations for therapy, and the most appropriate uses of diagnostic imaging. - Features expanded information on infections in the compromised host; immunomodulating agents and their potential use in the treatment of infectious diseases; and Ebola virus. - Contains hundreds of new color images throughout, as well as new guidelines, new resistance epidemiology, and new Global Health Milestones. - Includes new chapters on Zika virus and Guillain-Barré syndrome. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
Practical Genetic Counselling, Third Edition presents the progress in the field of medical genetics. This book covers the broad area of congenital malformation syndromes and dysmorphology. Organized into three parts encompassing 26 chapters, this edition begins with an overview of the main steps in the process of genetic counselling. This text then examines how a Mendelian inheritance may be established by a combination of clinical diagnosis. Other chapters consider the risks in specific groups of chromosomal disorders. This book discusses as well the molecular genetic approaches, which are making an impact in the treatment of major disorders by providing pure and comparatively inexpensive gene products. The final chapter deals with how genetic counselling is contributing to reducing the general burden of genetic disease in the population. This book is a valuable resource for geneticists, neurologists, clinicians, pediatricians, and obstetricians. Readers who are interested to know about genetic disorders will also find this book useful.
This is a completely new, second edition of the classic reference which has been out of print since 1984. It is the most comprehensive work available on placental pathology, which has recently gained importance in clinical medicine, and includes discussion of legal aspects dealing with the relation between placenta and perinatal damage.
Resulting from research into the needs of teachers arising from the revised syllabuses for GCSE Geography, and focusing on topical issues throughout the UK, this is one of a three-book series of supplementary topic books providing a range of detailed case studies, enquiries and decision-making exercises. The other two pupils' books cover Europe and the world, respectively, and there are teacher resource packs which correspond to all three.
#1 NEW YORK TIMES BESTSELLER • “I’ve read kind of all the books on this subject . . . and this is the one you want to read.”—Rachel Maddow Before Ukraine, before impeachment: This is the never-before-told inside story of the high-stakes, four-year-long investigation into Donald Trump’s Russia ties—culminating in the Steele dossier, and sparking the Mueller report—from the founders of political opposition research company Fusion GPS. Fusion GPS was founded in 2010 by Glenn Simpson and Peter Fritsch, two former reporters at The Wall Street Journal who decided to abandon the struggling news business and use their reporting skills to conduct open-source investigations for businesses and law firms—and opposition research for political candidates. In the fall of 2015, they were hired to look into the finances of Donald Trump. What began as a march through a mind-boggling trove of lawsuits, bankruptcies, and sketchy overseas projects soon took a darker turn: The deeper Fusion dug, the more it began to notice names that Simpson and Fritsch had come across during their days covering Russian corruption—and the clearer it became that the focus of Fusion’s research going forward would be Trump’s entanglements with Russia. To help them make sense of what they were seeing, Simpson and Fritsch engaged the services of a former British intelligence agent and Russia expert named Christopher Steele. He would produce a series of memos—which collectively became known as the Steele dossier—that raised deeply alarming questions about the nature of Trump’s ties to a hostile foreign power. Those memos made their way to U.S. intelligence agencies, and then to President Barack Obama and President-elect Trump. On January 10, 2017, the Steele dossier broke into public view, and the Trump-Russia story reached escape velocity. At the time, Fusion GPS was just a ten-person consulting firm tucked away above a Starbucks near Dupont Circle, but it would soon be thrust into the center of the biggest news story on the planet—a story that would lead to accusations of witch hunts, a relentless campaign of persecution by congressional Republicans, bizarre conspiracy theories, lawsuits by Russian oligarchs, and the Mueller report. In Crime in Progress, Simpson and Fritsch tell their story for the first time—a tale of the high-stakes pursuit of one of the biggest, most important stories of our time—no matter the costs.
Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. This multimedia e-dition includes not only the printed reference, but also access to the complete contents online, fully searchable, with regular updates and much more. The expertise of the contributors, the scope of the coverage, and the versatile, multimedia format all make this the ultimate reference for the practicing cardiologist. Locate the answers you need fast, thanks to a user-friendly, full-color design, complete with more than 1,500 color illustrations. Glean clinically actionable information quickly with Clinical Practice Points in every chapter. Access the complete contents of the 2-volume set online, fully searchable, plus regular updates to reflect the latest clinical developments · Focused Reviews · Commentaries · Late-Breaking Trials · and more. Apply the latest knowledge in your field with 7 new chapters on Acute Heart Failure · Device Therapy of Heart Failure · Emerging Therapies for Heart Failure · Complementary and Alternative Approaches to Management · Prevention and Management of Stroke · Hypertrophic Cardiomyopathy · and Coronary Arteriography Guidelines. Get fresh perspectives on your practice with contributions from more than 20 brand-new authors.
This informative new book presents an accessible account of the development of medical genetics over the past 70 years, one of the most important areas of 20th, and now 21st, century science and medicine. Based largely on the author’s personal involvement and career as a leader in the field over the last half century, both in the UK and internationally, it draws on his interest and involvement in documenting the history of medical genetics. Underpinning the content is a unique series of 100 recorded interviews undertaken by the author with key older workers in the field, the majority British, providing invaluable information going back to the very beginnings of human and medical genetics. Focusing principally on medically relevant areas of genetics rather than the underlying basic science and technological aspects, the book offers a fascinating insight for those working and training in the field of clinical or laboratory aspects of medical genetics, genomics and allied areas; it will also be of interest to historians of science and medicine and to workers in the social sciences who are increasingly attracted by the social and ethical challenges posed by modern medical genetics and genomics.
Shaft sinking for the extraction of minerals has taken place for centuries, and for much of this time, coal mining was carried out in the North East of England. Various methods of pit sinking developed from the use of shallow bell pits to the excavation of deep shafts, in order to access rich seams of coal and other minerals for sale in rapidly urbanising areas such as London. In the close mining communities of Northumberland and Durham, those who dug the initial shafts, the sinkers themselves, were regarded as the mining elite. This book not only tells the story of mining itself, through upheaval and technological developments, but also focuses on the lives of miners and their families above ground in the emerging pit towns adn villages; places where religion adn miners' galas were an integral part of life. Peter Ford Mason, descended from three generations of County Durham miners, has written a fascinating investigation onto miming society, which makes a compelling read for anyone interested in the social history of the North East or the mining industry as a whole.
Long recognized as a leading textbook in this fast-moving field, Emery's Elements of Medical Genetics and Genomics offers current, complete information with a strong basis in practical clinical genetics and genomics for medical school and beyond. The 16th Edition of this award-winning text has been thoroughly updated throughout and includes case-based and multiple-choice questions, end-of-chapter summaries, an extensive glossary, and convenient online access, making it an ideal choice for all medical undergraduates as well as postgraduates seeking to improve their understanding and knowledge. Includes new case-based studies with questions and answers throughout, in addition to multiple-choice self-assessment questions for study and review. Covers key topics such as pharmacogenetics, personalized medicine, prenatal testing, reproductive genetics, and ethical and legal issues in medical genetics. Divides the text into three easy-to-use sections: The Scientific Basis of Human Genetics, Genetics in Medicine and Genomic Medicine, and Clinical Genetics, Counseling and Ethics. Features full-color illustrations and other images that help readers visualize the appearance of genetic disorders and assist with the understanding of complex genetic structures. Contains learning features such as summary boxes, an extensive glossary of terms, online hyperlinks to important genetics websites and clinical databases, and more. Presents the extensive knowledge and experience of distinguished editors Peter D. Turnpenny and Sian Ellard, as well as new editor Ruth Cleaver.
THE REVIVAL AND RESTORATION of the Welsh Highland Railway is one of the greatest heritage railway achievements of the 21st Century, yet its success followed more than one hundred years of failure.Supported by public loans, its first incarnation combined the moribund North Wales Narrow Gauge Railways, some of the abandoned works of the Portmadoc, Beddgelert & South Snowdon Railway and part of the horse-worked Croesor Tramway. Opened in 1923, it was closed in 1937 and the track was lifted in 1941.Serious talk of revival started in the 1960s but restoration did not start until 1997, with the neighbouring Ffestiniog Railway at the helm, supported by generous donors and benefactors, the Millennium Commission, the Welsh Government and teams of enthusiastic volunteers.Author Peter Johnson steers a course through the railways complicated pre-history before describing the events, including a court hearing, three public inquiries and a great deal of controversy, leading to the start of services between Caernarfon and Porthmadog in 2011. A postscript describes post-completion developments.
Surgery, 3rd Edition, provides you with the most current knowledge and techniques hand and upper extremity plastic surgery, allowing you to offer every patient the best possible outcome. Access all the state-of-the-art know-how you need to overcome any challenge you may face and exceed your patients' expectations.
Pathology of the Human Placenta remains the authoritative text in the field and is respected and used by pathologists and obstetrician-gynecologists alike. This fifth edition reflects new advances in the field and includes 800 illustrations, 173 of them in color. The detailed index has been improved and the tables updated. Defined terms are highlighted in bold for easy identification, and further findings are discussed in small type throughout each chapter. Advances in genetics and molecular biology continue to make the study of the placenta one of vast diagnostic and legal importance.
Concise and clinically focused, Gout, by Drs. Naomi Schlesinger and Peter E. Lipsky, provides a one-stop overview of recent developments regarding this common form of inflammatory arthritis. Impacting an estimated 8.3 million people in the U.S. alone, gout is seen frequently by both primary care physicians as well as rheumatologists. This resource provides detailed coverage of the epidemiology, causes, diagnosis, management, and treatment of patients with both acute and chronic gout. - Addresses key topics such as genetics, hyperuricemia, comorbidities of gout, treatment guidelines for acute and chronic gout, classification and diagnosis, and imaging. - Discusses future outlooks for improving pharmacological and nonpharmacological treatment options, including an overview of drugs in the pipeline. - Consolidates today's available information on this timely topic into one convenient resource.
Pathology of the Human Placenta has become the gold standard in the field for pathologists and obstetrician-gynecologists. Completely up-to-date, this fifth edition continues to be the essential reference for professionals in the field and includes many revised features such as a more detailed index; 700 total illustrations (350 color illustrations); and updated tables.
Chronic obstructive pulmonary disease (COPD), which encompasses both chronic bronchitis and emphysema, is one of the most common respiratory conditions of adults in the developed world. Asthma and COPD: Basic Mechanisms and Clinical Management provides a unique, authoritative comparison of asthma and COPD. Written and edited by the world's leading experts, it is a comprehensive review of the most recent understanding of the basic mechanisms of both conditions, specifically comparing their etiology, pathogenesis, and treatments.* Highlights distinguishing features between asthma and COPD* Reviews benefits and limitations of current therapies* Summarises key information in two-colour artwork * Extensively referenced to primary literature
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