This book represents the first complete and systematic guide to the virus-like particles (VLPs) and their applications as vaccines, therapeutic tools, nanomaterials, and nanodevices. The grouping of the VLPs follows the most recent virus taxonomy and the traditional Baltimore classification of viruses, which are based on the genome structure and mechanism of mRNA synthesis. Within each of the seven Baltimore classes, the order taxon serves as a framework of the chapter’s arrangement. The term "VLP" is used as a universal designation for the virus-, core-, or capsid-like structures, which became an important part of the modern molecular virology. The 3D structures, expression systems, and nanotechnological applications are described for VLPs in the context of the original viruses and uncover their evolving potential as novel vaccines and medical interventions. Key Features Presents the first full guide to the VLP nanotechnology, classified by current viral taxonomy Outlines specific structural properties and interconnection of the virions and VLPs Explains generation and characteristics of VLPs produced by various expression systems Offers up-to-date summary of VLPs designed as vaccines and delivery tools Unveils interconnection of VLPs with novel organic and inorganic nanomaterials
Peter Swenson's study implies that contrary to popular wisdom the welfare state builders in the USA and Sweden during the 1930s were motivated by a pragmatism founded in capitalist interests and preferences.
New technological approaches in dermatologic diagnostics, such as surface microscopy and dermoscopy, are continuously advancing. Anatomical structures can be viewed like never before. Through these new techniques the necessity of a new terminology and a new set of dermoscopic criteria has come up. So far, many different and sometimes confusing terms have been used in designating these microscopic features. However, the daily challenge physicians face when evaluating skin lesions acquires immediate access to the current dermoscopic nomenclature and definition. This unique guide provides a comprehensive, current, and accurate A-Z encyclopaedia to clarify the meaning of surface microscopic and dermoscopic terminology including a broad range of both melanocytic and non-melanocytic skin lesions. It will support dermatologists, histopathologists and all other physicians in charge of a biopsy and excision decision.
This in-depth textbook with a focus on atom-light interactions prepares students for research in a fast-growing and dynamic field. Intended to accompany the laser-induced revolution in atomic physics, it is a comprehensive text for the emerging era in atomic, molecular and optical science. Utilising an intuitive and physical approach, the text describes two-level atom transitions, including appendices on Ramsey spectroscopy, adiabatic rapid passage and entanglement. With a unique focus on optical interactions, the authors present multi-level atomic transitions with dipole selection rules, and M1/E2 and multiphoton transitions. Conventional structure topics are discussed in some detail, beginning with the hydrogen atom and these are interspersed with material rarely found in textbooks such as intuitive descriptions of quantum defects. The final chapters examine modern applications and include many references to current research literature. The numerous exercises and multiple appendices throughout enable advanced undergraduate and graduate students to balance theory with experiment.
The perfect gift for aspiring leaders: The Peter F. Drucker Library. Filled with practical guidance on perennial leadership issues, the Peter F. Drucker Boxed Set is essential reading for all managers and executives. More vitally relevant than ever, each book features the best of Peter F. Drucker's legendary wisdom. This specially priced 8-volume set includes every book in the Drucker Library: Peter F. Drucker on Economic Threats; Peter F. Drucker on Technology; Peter F. Drucker on Business and Society; Peter F. Drucker on Nonprofits and the Public Sector; Peter F. Drucker on the Network Economy; Peter F. Drucker on Management Essentials; Peter F. Drucker on Globalization; and Peter F. Drucker on Practical Leadership. Build your professional library with the Peter F. Drucker Boxed Set.
This is a timely book. The question of how to help people with challenging behaviour -and how to design and manage services so that staff, families and users feel that what should be done is being done - is at the top of the agenda. Failure to deal com petently with the issue results in disaffection, poor quality ser vices and a less than optimal quality of life for service users. Moreover, the credibility of services for all people with learning disabilities is intimately connected with how we cope with chal lenging behaviour, a point made recently by a Department of Health Working Group chaired by Jim Mansell (Department of Health, 1993). The book is welcome because it draws together what is known about the important questions from a British perspective, although, of course, most of the underlying issues have world wide relevance. The contributors, while all having a good deal of experience and authority, do not put forward simple portrayals of the problems, nor glib solutions, and this is one of the book's major strengths. Clarity in the field of challenging behaviour is sometimes elu sive. What is presented here forces the reader to confront argu ments in a rational and logical fashion.
Managing in a Globalized Economy In this collection of essays, renowned management thinker and teacher Peter F. Drucker guides leaders on how to find opportunities and make the right decisions in a business context that is increasingly global. This collection delivers a set of urgently needed lessons on how business leaders today can manage through complexity and volatility—and make the wisest possible choices while balancing the perils and promise of globalization. Using in-depth stories and examples from a diverse range of sectors, industries, and geographies, Drucker offers managers insight into: The global economic trends impacting world trade The productivity of the global workforce Managing major organizational decisions in a turbulent environment Both timely and enduring, Peter F. Drucker on Globalization is a forward-looking guidebook packed with practical wisdom.
Kiumajut [Talking Back]: Game Management and Inuit Rights 1900-70 examines Inuit relations with the Canadian state, with a particular focus on two interrelated issues. The first is how a deeply flawed set of scientific practices for counting animal populations led policymakers to develop policies and laws intended to curtail the activities of Inuit hunters. Animal management informed by this knowledge became a justification for attempts to educate and, ultimately, to regulate Inuit hunters. The second issue is Inuit responses to the emerging regime of government intervention. The authors look closely at resulting court cases and rulings, as well as Inuit petitions. The activities of the first Inuit community council are also examined in exploring how Inuit began to “talk back” to the Canadian state. The authors’ award-winning previous collaboration, Tammarniit [Mistakes]: Inuit Relocation in the Eastern Arctic 1939-63, focused on government responsibility, social welfare, and relocation in Inuit relations with the state. Kiumajut is not a continuation of Tammarniit, but rather an interrelated, stand-alone study that examines a separate range of issues relevant to a historical understanding of community development in Nunavut. Kiumajut draws on new material compiled from archival sources and from an archive of oral interviews conducted by the authors with Inuit elders and others between 1997 and 1999. This volume provides the reader with new and important insights for understanding this critical period in the history of Inuit in Canada.
This century has seen the development of technologies for manipulating and controlling matter and light at the level of individual photons and atoms, a realm in which physics is fully quantum-mechanical. The dominant experimental technology is the laser, and the theoretical paradigm is quantum optics.The Quantum World of Ultra-Cold Atoms and Light is a trilogy, which presents the quantum optics way of thinking and its applications to quantum devices. This book — 'Ultra-Cold Atoms' — provides a theoretical treatment of ultra-cold Bosons and Fermions and their interactions with electromagnetic fields in a form consistent with the first two books in the trilogy.The central concept is the quantum stochastic paradigm, formulated for cold collision physics. For Bosons, this yields a suite of techniques; versions of the stochastic Gross-Pitaevskii equation, using which a wide range of dynamic and thermal properties are formulated.The eBook editions of the 'Quantum World Trilogy' feature an extensive system of hyperlinks for ease of cross reference within the books, as well as links to the other books in the trilogy. In the section Viewing the eBooks we explain how these links work, and give some advice on appropriate pdf viewer applications.
The Frontiers of Management offers stimulating and profitable reading for both existing Drucker disciples and those new to his writing. This collection of thirty-five finely balanced articles and essays, plus an interview and afterword, was planned by the author from the beginning to be published eventually in one volume and as variations on one unifying theme - the challenges of tomorrow that face the executive today. What kind of tomorrow it will be depends heavily on the knowledge, insight, foresight and competence of the decision makers of today. The future is in the hands of executives who are already fully occupied with the daily crisis, and for whom the daily crisis is the one absolutely predictable event in their working day. It is to these people that this Drucker volume is addressed, to enable them to see and to understand the long-range implications and impacts of their immediate, everyday, urgent actions and decisions.
The renormalization group (RG) has nowadays achieved the status of a meta-theory, which is a theory about theories. The theory of the RG consists of a set of concepts and methods which can be used to understand phenomena in many different ?elds of physics, ranging from quantum ?eld theory over classical statistical mechanics to nonequilibrium phenomena. RG methods are particularly useful to understand phenomena where ?uctuations involving many different length or time scales lead to the emergence of new collective behavior in complex many-body systems. In view of the diversity of ?elds where RG methods have been successfully applied, it is not surprising that a variety of apparently different implementations of the RG idea have been proposed. Unfortunately, this makes it somewhat dif?cult for beginners to learn this technique. For example, the ?eld-theoretical formulation of the RG idea looks at the ?rst sight rather different from the RG approach pioneered by Wilson, the latter being based on the concept of the effective action which is ite- tively calculated by successive elimination of the high-energy degrees of freedom. Moreover, the Wilsonian RG idea has been implemented in many different ways, depending on the particular problem at hand, and there seems to be no canonical way of setting up the RG procedure for a given problem.
Keeping up with the rapidly growing research base, the leading graduate-level psychology of religion text is now in a fully updated fifth edition. It takes a balanced, empirically driven approach to understanding the role of religion in individual functioning and social behavior. Integrating research on numerous different faith traditions, the book addresses the quest for meaning; links between religion and biology; religious thought, belief, and behavior across the lifespan; experiential dimensions of religion and spirituality; the social psychology of religious organizations; and connections to coping, adjustment, and mental disorder. Chapter-opening quotations and topical research boxes enhance the readability of this highly instructive text. New to This Edition *New topics: cognitive science of religion; religion and violence; and groups that advocate terrorist tactics. *The latest empirical findings, including hundreds of new references. *Expanded discussion of atheism and varieties of nonbelief. *More research on religions outside the Judeo-Christian tradition, particularly Islam. *State-of-the-art research methods, including techniques for assessing neurological states.
Handbook of Evidence-Based Practice in Clinical Psychology, Volume 1 covers the evidence-based practices now identified for treating children and adolescents with a wide range of DSM disorders. Topics include fundamental issues, developmental disorders, behavior and habit disorders, anxiety and mood disorders, and eating disorders. Each chapter provides a comprehensive review of the evidence-based practice literature for each disorder and then covers several different treatment types for clinical implementation. Edited by the renowned Peter Sturmey and Michel Hersen and featuring contributions from experts in the field, this reference is ideal for academics, researchers, and libraries.
Settling and Unsettling Memories analyses the ways in which Canadians over the past century have narrated the story of their past in books, films, works of art, commemorative ceremonies, and online. This cohesive collection introduces readers to overarching themes of Canadian memory studies and brings them up-to-date on the latest advances in the field. With increasing debates surrounding how societies should publicly commemorate events and people, Settling and Unsettling Memories helps readers appreciate the challenges inherent in presenting the past. Prominent and emerging scholars explore the ways in which Canadian memory has been put into action across a variety of communities, regions, and time periods. Through high-quality essays touching on the central questions of historical consciousness and collective memory, this collection makes a significant contribution to a rapidly growing field.
The Best of Peter F. Drucker on Non-Profits and the Public Sector Peter F. Drucker's classic and timeless insights on improving effectiveness in the public sector--including government agencies, hospitals, universities, and other nonprofits--are as relevant now as when they were written. In these prescient essays, Drucker explores the merits of proper governance for nonprofits and the public sector by offering advice and guidance on effective business management strategies to help leaders of these organizations better understand, and manage, the complex challenges they face in our volatile world. Public sector leaders will learn how to apply many of Drucker's trusted management practices to nonprofits. In this practical guide, Drucker offers insights on a range of perennial issues: the global economy board governance environmental challenges succession planning and other essential management topics Packed with evergreen advice from the world's most trusted management thinker, Peter F. Drucker on Nonprofits and the Public Sector is regarded as essential reading for all leaders in this sector of the economy.
Neoplastic mimics or "pseudotumors" can simulate neoplasms on all levels of analysis- clinical, radiologic, and pathologic--and thus represent particular diagnostic pitfalls for the pathologist that can ultimately lead to therapeutic misdirection. This book provides the pathologist with detailed morphologic descriptions and diagnostic guidance in recognizing these neoplastic mimics as they occur in the genitourinary system. In addition, descriptions and diagnostic guidance are provided for the range of genitourinary lesions tumors that may mimic benign masses but are in fact neoplastic. Throughout the book comparisons of neoplastic mimics with true neoplasms are provided, at clinical, gross, and histologic levels. In the presentation of every entity, the points that contribute to differential diagnosis are emphasized. More than 500 color images and this analysis of diagnostic mimics guide the pathologist through recognizing and distinguishing the unusual variants, morphologic anomalies and misleading features that may easily lead to an inaccurate interpretation and missed diagnosis. Since many of entities described are uncommon Neoplastic Mimics in Genitourinary emphasizes imaging and clinical correlations throughout to support the pathologist as consultant to the entire diagnostic and clinical management team. Every pathologist who sees genitourinary cases will find this book an invaluable working tool to ensure accurate diagnosis. Neoplastic Mimics in Genitourinary Pathology features: Over 500 high-quality images showing the full range of neoplastic mimics in the genitourinary tract Concise, specific text descriptions make the book easy to use as a visual reference Expert authors guide the reader to recognizing and distinguishing misleading specimens
Advances in the Canine Cranial Cruciate Ligament, Second Edition presents in-depth, focused, and updated coverage of current knowledge on cruciate ligament rupture, using a multidisciplinary, evidence-based approach. Presents a state-of-the-art summary of the most recent knowledge on this important cause of lameness in dogs Led by a highly respected surgeon and researcher, with chapters written by leading experts in the field Provides an update to the groundbreaking first edition, with six new chapters
A new history shows how FDR developed a vision of national security focused not just on protecting Americans against physical attack but also on ensuring their economic well-being—and how the nascent conservative movement won the battle to narrow its meaning, durably reshaping US politics. Americans take for granted that national security comprises physical defense against attacks. But the concept of national security once meant something more. Franklin Roosevelt’s vision for national security, Peter Roady argues, promised an alternate path for the United States by devoting as much attention to economic want as to foreign threats. The Contest over National Security shows how a burgeoning conservative movement and power-hungry foreign policy establishment together defeated FDR’s plans for a comprehensive national security state and inaugurated the narrower approach to national security that has dominated ever since. In the 1930s, Roosevelt and his advisors, hoping to save the United States from fascism and communism, argued that national security entailed protection from both physical attack and economic want. Roosevelt’s opponents responded by promoting a more limited national security state privileging military defense over domestic economic policy. Conservatives brought numerous concerns to bear through an enormous public relations offensive, asserting not just that Roosevelt’s plans threatened individual freedom but also that the government was less competent than the private sector and incapable of delivering economic security. This contest to define the government’s national security responsibilities in law and in the public mind, Roady reveals, explains why the United States developed separate and imbalanced national security and welfare states, with far-reaching consequences. By recovering FDR’s forgotten vision, Roady restores a more expansive understanding of national security’s meanings as Americans today face the great challenges of their times.
Far from a sign of healthy prosperity and contentment, overweight and obesity are now considered high risk factors for a wide range of diseases including early death and disability, heart disease, diabetes, reproductive problems, cancer, breathing problems and arthritis. Obesity, now at epidemic levels in many countries, is defined as an excessively high amount of body fat or adipose tissue in relation to lean body mass. The amount of body fat (or adiposity) includes concern for both the distribution of fat throughout the body and the size of the adipose tissue deposits. This book includes within its scope the causal connection of obesity to diseases as well as the prevention and treatment of obesity. Leading-edge scientific research from throughout the world is presented in this book.
Practical and highly illustrated, Genital Dermatology Manual, 4th Edition, by Drs. Libby Edwards and Peter J. Lynch, helps clinicians at all levels of experience arrive at an accurate diagnosis for both common and rare genital dermatologic lesions. More than 500 full-color photographs are arranged by appearance for rapid identification, offering superb visual guidance even for conditions not previously encountered. This easy-to-use reference is ideal for any clinician who sees men and women with disorders of the external genitalia, including dermatologists, gynecologists, urologists, primary care physicians, nurse practitioners, nurse midwives, and physician assistants.
A collection of Peter Ferdinand Drucker's legendary essays on business, management, economics and society, written between 1972 and 1980. They reflect an international viewpoint and are concerned with what Drucker called "social ecology" and especially institutions - governments, organized science, business or schools. This hardcover release is being published as part of the Harvard Business Press Drucker Library.
Evidence-Based Practice and Intellectual Disabilities responds to the recent increased focus on, and need for, the use of evidence-based practice (EBP) in treating intellectual disabilities. The first book wholly dedicated to addressing EBP specifically in relation to intellectual disabilities Provides clinical guidelines based on the strength of evidence of treatments for a given problematic behavioral topography or disorder Highly relevant to a wide-ranging audience, including professionals working in community services, clinicians and parents and carers
This issue of Thoracic Surgery Clinics of North America, guest edited by Dr. Peter Licht, is devoted to Management of Hyperhidrosis. Dr. Licht has assembled expert authors to review the following topics: History of Sympathetic Surgery; Pathophysiology of Hyperhidrosis; Emerging Nonsurgical Treatments for Hyperhidrosis; Selecting the Right Patient for Surgical Treatment of Hyperhidrosis; Targeting the Sympathetic Chain for Primary Hyperhidrosis: An Evidence-Based Review; Reversibility of Clipping for Primary Hyperhidrosis; Robotic Sympathectomy; Reconstruction of the Sympathetic Chain; Quality of Life Changes Following Surgery for Hyperhidrosis; Management of Compensatory Sweating after Sympathetic Surgery; Less Common Side Effects Following Sympathetic Surgery; Facial Blushing: Patient Selection and Long Term Results; Management of Plantar Hyperhidrosis; and more!
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.
Magnetic resonance imaging (MRI) has become the leading cross-sectional imaging method in clinical practice. Continuous technical improvements have significantly broadened the scope of applications. At present, MR imaging is not only the most important diagnostic technique in neuroradiology and musculoskeletal radiology, but has also become an invaluable diagnostic tool for abdominal, pelvic, cardiac, breast and vascular imaging. This book offers practical guidelines for performing efficient and cost-effective MRI examinations in daily practice. The underlying idea is that, by adopting a practical protocol-based approach, the work-flow in a MRI unit can be streamlined and optimized. For the second edition, all chapters have been thoroughly reviewed, and new techniques and figures were included. This book will help beginners to advance their starting point in implementing the protocols and will aid more experienced users in updating their knowledge.
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