Through case studies, this book makes sense of the profound revolution that historical biogeography has undergone in the last two decades, and of the resulting confusion over its foundations, basic concepts, methods, and relationships to other disciplines of comparative biology.
For Dummies Travel guides are the ultimate user-friendly trip planners, combining the broad appeal and time-tested features of the For Dummies series with up-to-the-minute advice and information from the experts at Frommer’s. • Small trim size for use on-the-go • Focused coverage of only the best hotels and restaurants in all price ranges • Tear-out “cheat sheet” with full-color maps or easy reference pointers San Francisco is one of the most exciting, inviting, unique, and eclectic cities in the world. From the Golden Gate Bridge to Lombardy Street to the Embarcadero…from Little Italy to Chinatown to Russian Hill, there’s an invigorating mix of attractions and cultures. This friendly guide helps you zero in on your "must sees" and plan your personal itinerary. Enjoy incredible upscale shopping or bargain-hunting in Chinatown, browse for books at City Lights, or hit Haight Street or Hayes Street for the latest trends Choose from all kinds of entertainment options, ranging from a Giants game to grand opera to theater to blues to leather-clad, fire-dancing performance artists Have a romantic dinner at Absinthe or Quince, sip a cappuccino in North Beach, enjoy authentic Italian pastas, or try the catch of the day Take a day trip to Berkeley, an overnighter to the coast, or a getaway to Wine Country, including winery tours and a mud bath Like every For Dummies travel guide, San Francisco For Dummies, 5th Edition helps you make the most of your vacation. It includes: Down-to-earth trip-planning advice Info on the best ships for every budget Tips on sightseeing at ports of call Handy Post-it Flags to mark your favorite pages Whether you want to experience the thrills and views provided by the cable cars, escape from Alcatraz, climb Telegraph Hill, bike in Golden State Park, or simply relax in a room with a private outdoor soaking tub, this guide helps you find your way in the City by the Bay.
Marine organisms have been increasingly regarded as excellent sources of new drugs for human therapeutics due to their remarkable chemistry, which, in turn, is reflected in their wide range of biological applications, including cancer, inflammation, infection, and pain. In the past 20 years, several new drugs have been discovered, some of them with novel pharmacological targets and the first sea-derived approved medicines are now paving their way into the market. In this chapter, we will focus on small-molecule drugs obtained from marine animals (sponges, gorgonians, mollusks, echinoderms) for the treatment of inflammation. The distribution of these compounds by different taxonomical families will be discussed, as well as the state-of-the-art regarding their structure–activity relationship. The most important chemical classes will be presented, such as terpenes, alkaloids, among others. The most important molecular targets, including phospholipase A2 (PLA2), cyclooxygenases (COXs), nitric oxide synthase (NOS), and NF-κB will be discussed.
With two of the nation’s largest megalopolises — Los Angeles and the San Francisco Bay area—California has the largest, wealthiest, and most urbanized population of any state in the nation. Yet it’s also an agricultural wonderland, a nature-lovers paradise, a wine-lover’s dream, an outdoor enthusiast’s ideal playground, and more. In fact, there’s so much to see and do in California that you’ll probably have to choose. With this guide, you can’t lose. It gives you the scoop on: Northern California, including San Francisco, the Napa and Sonoma Valleys, Redwood Country, Yosemite National Park, and more The central coast, including the Monterey Peninsula and the spectacular Big Sur Coast The Southland cities, including L.A., San Juan Capistrano and Laguna Beach, ritzy Palm Springs, and San Diego Major attractions like Hearst Castle, Disneyland, the San Diego Zoo, and Alcatraz Activities like hiking in the Yosemite Valley, biking along the Monterey coastline, cruising Sunset Boulevard, taking in the scenery on the Pacific Coast Highway, and more All kinds of dining options, ranging from foodie favorites like the French Laundry in Yountville and Campanile, Patina, and Providence in L. A. to good restaurants for picky eaters, and great places to enjoy a vegetarian meal or incredible Vietnamese, Italian, Mexican, or Thai specialties Can’t miss family destinations in various parts of the state, including Humboldt Redwood State Park, the Santa Cruz Beach Boardwalk, the Monterey Bay Aquarium, the California Science Center, in L.A., and more All sorts of accommodations, from new Treebones Resort in Big Sur that houses you in a gorgeous yurt, L. A.’s Chateau Marmont, with its Art Deco and Beaux Arts castle-style main building and individual bungalows, the Grand View and Seven Gables inns in Monterey/Pacific Grove with their spectacular ocean views, Chateau du Sureau in Oakhurst for pure pampering and four-star dining, and more Like every For Dummies travel guide, California For Dummies, 4th Edition includes: Down-to-earth trip-planning advice What you shouldn’t miss — and what you can skip The best hotels and restaurants for every budget Handy Post-it Flags to mark your favorite pages Complete with all kinds of planning tips plus actual time-tested itineraries, this covers the must-see attractions, suggests things to see or do that are off the beaten path, and answers questions you might not even think to ask, like where to go to get down and wacky the way actual Californians do, where to find great inexpensive, gifts, and even where to find the graves of some of Hollywood’s biggest stars. With this guide, you’ll soon be singing, "California, here I come.
With frenetic pace and a hypnotic plot, Urgent Matters is an essential read." --Agustina Bazterrica, author of Tender is the Flesh An electric Argentinian thriller featuring a deadly train crash, two unidentified bodies, and a missing murder suspect--perfect for fans of Attica Locke and Steph Cha The Americans are more astute when it comes to matters like these. They say “not guilty”. They don’t say “innocent”. Because as far as innocence goes, no one can make that claim. A train crashes in the suburbs of Buenos Aires, leaving forty-three fatalities, two of which have not been identified. A prayer card of Saint Expeditus, the patron saint of urgent matters, flutters above the wreckage. Hugo, a criminal on the run for murder, is on the train. He seizes his chance to sneak out of the wreckage unsuspected, abandoning his possessions – and, he hopes, his identity – among bodies mangled beyond recognition. As the police descend on the scene, only grizzled Detective Domínguez sees a link between the crash and his murder case. Soon, he’s on Hugo’s tail. But he hasn’t banked on everything from the media to his mother-in-law getting in the way.
This book, the most-up-to-date guide to Guatemala, is all you need to explore the heart of the Mayan world. Whether you want to wander the steamy, jungle ruins of Tikal, climb the active cone of the Volcan de Fuego, stroll the cobblestone streets of Antigua, or browse through traditional indigenous markets, VIVA will help you get the most from your time in this beautiful country.
Interrupted Life is a gripping collection of writings by and about imprisoned women in the United States, a country that jails a larger percentage of its population than any other nation in the world. This eye-opening work brings together scores of voices from both inside and outside the prison system including incarcerated and previously incarcerated women, their advocates and allies, abolitionists, academics, and other analysts. In vivid, often highly personal essays, poems, stories, reports, and manifestos, they offer an unprecedented view of the realities of women's experiences as they try to sustain relations with children and family on the outside, struggle for healthcare, fight to define and achieve basic rights, deal with irrational sentencing systems, remake life after prison; and more. Together, these powerful writings are an intense and visceral examination of life behind bars for women, and, taken together, they underscore the failures of imagination and policy that have too often underwritten our current prison system.
Profiles model arts-based substance abuse prevention programs for youth & communities in a variety of disciplines & settings. Highlighted programs include: Tuscon's Project Choli & Old Pascua Youth Artists; San Francisco's Vietnamese Youth Dev. Center Peer Resource Program; Bronx Council on the Arts, WritersCorp; CHIL'ART Playwrights Program of New Brunswick, N.J.; Little Rock's CornerStone Project NETworks Center; Chicago's Music Theater Workshop Under Pressure series; Iowa City's United Action for Youth Synthesis Arts Workshop; & Teen Resource Project/New Visions/Nueva Visiones Theater of Holyoke, MA.
The most up-to-date Bolivia travel guidebook on the market, this book helps to to successfully navigate and explore this beautiful country. Wander the salt flats, visit the highest capital in the world, and while you're at it, the highest navigable lake. Wildlife-watch in the steamy jungles of Parque National Madidi or travel back in time at the mines of Potosi. With VIVA's book in tow, you won't miss anything.
Nelly, la vida de una mujer mexicana, nos pinta una sociologia del Siglo XX en Mexico. Narrada con todo el amor de una abuela, endulzada por una genealogia de historias y escalonadas de estratos sociales. Su infancia a principios de siglo en la capital, su adolescencia repartida por el centro de la Republica y su vida de casada paralela al ferrocarril desde donde proyecto su vida.
Though biogeography may be simply defined--the study of the geographic distributions of organisms--the subject itself is extraordinarily complex, involving a range of scientific disciplines and a bewildering diversity of approaches. For convenience, biogeographers have recognized two research traditions: ecological biogeography and historical biogeography. This book makes sense of the profound revolution that historical biogeography has undergone in the last two decades, and of the resulting confusion over its foundations, basic concepts, methods, and relationships to other disciplines of comparative biology. Using case studies, the authors explain and illustrate the fundamentals and the most frequently used methods of this discipline. They show the reader how to tell when a historical biogeographic approach is called for, how to decide what kind of data to collect, how to choose the best method for the problem at hand, how to perform the necessary calculations, how to choose and apply a computer program, and how to interpret results.
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