Climate change is now doing far more harm than marooning polar bears on melting chunks of ice—it is damaging the health of people around the world. Brilliantly connecting stories of real people with cutting-edge scientific and medical information, Changing Planet, Changing Health brings us to places like Mozambique, Honduras, and the United States for an eye-opening on-the-ground investigation of how climate change is altering patterns of disease. Written by a physician and world expert on climate and health and an award-winning science journalist, the book reveals the surprising links between global warming and cholera, malaria, lyme disease, asthma, and other health threats. In clear, accessible language, it also discusses topics including Climategate, cap-and-trade proposals, and the relationship between free markets and the climate crisis. Most importantly, Changing Planet, Changing Health delivers a suite of innovative solutions for shaping a healthy global economic order in the twenty-first century.
From the development of each vaccine to its use in reducing disease, Plotkin's Vaccines, 7th Edition, provides the expert information you need to provide optimal care to your patients. This award-winning text offers a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Includes complete information for each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, epidemiology, and public health and regulatory issues – plus complete information for each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Covers the new oral cholera and zoster vaccines, as well as newly licensed meningococcal group B vaccines and a newly licensed dengue vaccine. - Brings you up to date on successful human trials of Ebola vaccines, an enterovirus 71 vaccine licensed in China, and new recommendations and changes to polio vaccines. - Features a new chapter on maternal immunization. - Expert ConsultTM eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.
This book constitutes the thoroughly refereed postproceedings of the Joint International Workshop on Multi-Agent and Multi-Agent-Based Simulation, MABS 2004, held in New York, NY, USA in July 2004. The 20 revised full papers presented have gone through two rounds of reviewing, selection, and improvement; they present state-of-the-art research results in agent-based simulation and modeling. The papers are organized in topical sections on simulation of multi-agent systems, techniques and technologies, methodology and modeling, social dynamics, and application.
From the latest vaccination evidence, recommendations, and protocols . . . to new vaccine development and the use of vaccines in reducing disease, Plotkin's Vaccines, 8th Edition, covers every aspect of vaccination. Now completely revised and updated from cover to cover, this award-winning text continues to provide reliable information from global authorities, offering a complete understanding of each disease, as well as the latest knowledge of both existing vaccines and those currently in research and development. Described by Bill Gates as "an indispensable guide to the enhancement of the well-being of our world," Plotkin's Vaccines is a must-have reference for current, authoritative information in this fast-moving field. - Contains all-new chapters on COVID-19, vaccine hesitancy, and non-specific effects of vaccines, as well as significantly revised content on new vaccine technologies such as mRNA vaccines, emerging vaccines, and technologies to improve immunization. - Presents exciting new data on evolution of adjuvants across the centuries, dengue vaccines, human papillomavirus vaccines, respiratory syncytial virus vaccines, tuberculosis vaccines, and zoster vaccines. - Provides up-to-date, authoritative information on vaccine production, available preparations, efficacy and safety, and recommendations for vaccine use, with rationales and data on the impact of vaccination programs on morbidity and mortality. - Provides complete coverage of each disease, including clinical characteristics, microbiology, pathogenesis, diagnosis, and treatment, as well as epidemiology and public health and regulatory issues. - Keeps you up to date with information on each vaccine, including its stability, immunogenicity, efficacy, duration of immunity, adverse events, indications, contraindications, precautions, administration with other vaccines, and disease-control strategies. - Covers vaccine-preventable diseases, vaccine science, and licensed vaccine products, as well as product technologies and global regulatory and public health issues. - Analyzes the cost-benefit and cost-effectiveness of different vaccine options. - Helps you clearly visualize concepts and objective data through an abundance of tables and figures. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
In this book Steinhauer brings together the fragmented research that has been done in a number of different disciplines. From this body of work he develops a model of intervention based on an understanding of attachment theory, development theory, and the practice of mental health consultation.
Robin Paul Malloy examines efforts at urban development and revitalization as prototypical examples of a monumental transformation in American law. His investigation reveals that America has rejected a belief in the marketplace, individual freedom, and autonomy, and has instead opted for an ideological commitment to concepts contrary to the rhetoric upon which this country was founded. The urban landscape and its ideological infrastructure are being corrupted by greedy special interest groups and a political system unable to avoid its own excesses. This book is unique in its blending of legal and economic analysis. With a detailed and fresh new interpretation of Adam Smith, Malloy undertakes to challenge some of the most highly promoted urban panning devices and concludes that American law and values are in transformation. He also examines the legal and economic arrangements that have led America down this path of ideological drift and focuses on examples of urban revitalization efforts in several cities, including Indianapolis, Boston, Pittsburgh, St. Louis, and Louisville. Recommendations for change are provided. Fundamentally, however, he concludes that change must begin with the reinvigoration of individual values—values that respect individual freedom, liberty, and human dignity—values being readily displaced by the current ideological drift of American legal and economic culture. Planning for Serfdom is an important and controversial book that will be of interest to scholars and students of law, economics, politics, and philosophy.
There is an old Jewish adage that pretty much sums up Israel’s experience among the nations for the last 2,000 years. “Scratch a gentile,” the saying goes, “and you’re sure to find an anti-Semite.” That notion is given credence by the fact that the first two millennia of the Jewish-Christian encounter culminated in the systematic slaughter of six-million Jews in the heart of Christendom. But Dr. Paul R. Carlson, author of Christianity After Auschwitz, is cautiously optimistic that the dawn of this new millennium may lead to Jewish-Christian amity as the Church faces up to its past sins and seeks to work with the Synagogue against those demonic forces which threaten civilization itself. However, as Carlson illustrates, the genocidal germ that gave birth to Hitler’s criminal regime still flourishes among countless Christians, many of whom would passionately deny they harbor any anti-Semitic notions or sentiments. While the book is addressed primarily to Carlson’s fellow evangelicals, both Jews and Christians will discover that it provides the general reader with an overview of those critical issues which scholars alone have in the past wrestled with in the post-Holocaust Jewish-Christian encounter. At the outset, Carlson is quick to concede that the late Rabbi Joseph B. Soloveitchik, a scion of the great Chechnowa Rebbe, was certainly correct when he insisted that “Christians have never tried to penetrate the soul of the Jews. “They have read the Bible but neglected the oral tradition by which we interpret it,” he noted. “This makes a different Bible altogether. For example, says Rav Soloveitchik: “To equate Judaism with legalism the way Christian theologians are prone to do is like equating mathematics with a compilation of mathematical equations.” By the same token, old stereotypes die hard. “The Jew has been pictured as the arch-capitalist and the arch-Bolshevik and chastised for being both, whipsawed by contending forces,” says Nathan C. Belth. “The Soviet authorities [saw] Jews as a threat to the state, and Alexander Solzhenitsyn, who castigate[d] Soviet terror, sees Jews as libertarians who brought on socialism, after, of course, rejecting Christ.” Since time-immemorial, anti-Semites have also portrayed the Jew as the greedy, shady businessman or banker. But they conveniently forget stories such as that of Haym Salomon [1740-1785], the Jewish broker whose financial aid staved off starvation and desertion among American troops during our War for Independence. At one critical point, Robert Morris, the American financier and statesman, sent a messenger to alert Haym Salomon of the plight of the cash-strapped Colonial forces. The man brought the news to Salomon while he was attending Yom Kippur services at Mikveh Israel Synagogue in Philadelphia. The congregation was shocked at the intrusion on the holiest day of the Jewish year; but Haym Salomon quietly informed the messenger: “Tell Mr. Morris our country’s appeal will not be in vain.” But that old canard about Jews and their money remains grist for the anti-Semite’s mill. By the same token, Jews have not been entirely blameless when it comes to their own stereotypes of Christians, particularly evangelicals. Nathan Perlmutter confessed as much during his tenure as national director of the Anti-Defamation League (ADL) of B’nai B’rith. “Our image of the fundamentalist and the evangelical is a kind of collage assembled out of bits and pieces from Theodore Dreiser, Sinclair Lewis and Erskine Caldwell . . . ,” he admitted. “Even after all this time memories of the great swarm of sex-ridden, Bible-thumping caricatures continue to exert a pervasive power.” But evangelicals would be among the first to admit that Jews have come a long way since the days of the infamous Toledot Yeshu, or Life of Jesus, which depicted the Galilean in scandalous terms. Indeed, the Israeli author Shalom Ben-Chorin is representative of those Jewish intellectuals who now believe that “it is time for Jesus to come home again.” Meanwhile, few Christians realize just how vulnerable many Jews feel in what they perceive to be “Christian America.” That perception is heightened by the 1992 American Jewish Year Book finding that “roughly 12 percent of Americans of Jewish heritage are now Christians.” “There is another way of looking at what I have called a disaster in the making,” says former US Assistant Secretary of State Elliott Abrams, author of Faith or Fear: How Jews Can Survive in a Christian America “Of the 6.8 million people who are Jews or of Jewish descent, 1.1 million say they have no religion and 1.3 million have joined another religion, adding up to 2.4 million,” Abrams observes. “This means that one-third of the people in America of Jewish ethnic origin no longer report Judaism as their current religion (Abrams italics). Such statistics illustrate why Jewish leaders unanimously condemn those Christian missionary agencies which specifically target Jews for conversion. They have been particularly incensed by one recent evangelical effort, known as Peace 2000, which aimed to convert every Jew in Israel to Christianity by the dawn of the new millennium. “Centuries of martyrdom are the price which the Jewish people has paid for survival,” says Brandeis scholar Marshall Sklare. “And the apostate, at one stroke, makes a mockery of Jewish history. “But if the convert is contemptible in Jewish eyes,” Sklare adds, “the missionary — all the more, the missionary of Jewish descent -- is seen as pernicious, for he forces the Jew to relive the history of his martyrdom, all the while pressing the claim that in approaching the Jew he does so out of love. “What kind of love is it, Jews wonder, that would deprive a man of his heritage,” Sklare asks. “Furthermore, given the history of Christian treatment of the Jews, would it not seem time at last to recognize that the Jew has paid his dues and earned the right to be protected from obliteration by Christian love as well as destruction by Christian hate?” The distinguished Rabbi Abraham Joshua Heschel was even more pointed about the matter. “I had rather enter Auschwitz,” he once remarked, “than be an object of conversion.” All of this leads to the opening chapter of Christianity After Auschwitz, which introduces Christians to Emil Fackenheim’s “Eleventh Commandment” — or 614th Mitzvoth — which decrees that Jews are not permitted to grant Hitler any posthumous victories through intermarriage, assimilation, or conversion to a faith not their own. In a word, they are commanded to remain Jews. By the same token, Jewish scholars are quick to recognize that any “open and honest” dialogue will at some point involve a frank discussion of the similarities and differences between the Jewish and Christian perception[s] of the Messianic hope. With that understanding, the second chapter deals with the remarkable career of the late Rabbi Menachem Mendel Schneerson, the seventh and last Grand Rebbe of the Chabad Lubavitch Hasidim. Many of his talmidim, or disciples, believe he will ultimately be revealed as King-Messiah. His life and work are considered within the context of that of Jesus of Nazareth, as well as those of several pseudo-messiahs who have troubled Israel down through the centuries The author then makes it clear that Jesus himsel
Bringing together the top names in the field, this sharply clinical ye t user friendly work aims to educate pediatricians, family practitione rs and other health care providers about the special issues pertaining to the management of headache in children and adolescents. This is an exciting area with new indications for adolescents of drugs heretofor e approved only for adults.
Through four editions, Cummings Otolaryngology has been the world's most trusted source for comprehensive guidance on all facets of head and neck surgery. This 5th Edition - edited by Paul W. Flint, Bruce H. Haughey, Valerie J. Lund, John K. Niparko, Mark A. Richardson, K. Thomas Robbins, and J. Regan Thomas – equips you to implement all the newest discoveries, techniques, and technologies that are shaping patient outcomes. You'll find new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics such as Botox. Plus, your purchase includes access to the complete contents of this encyclopedic reference online, with video clips of key index cases! Overcome virtually any clinical challenge with detailed, expert coverage of every area of head and neck surgery, authored by hundreds of leading luminaries in the field. See clinical problems as they present in practice with 3,200 images - many new to this edition. Consult the complete contents of this encyclopedic reference online, with video clips of key index cases! Stay current with new chapters on benign neoplasms, endoscopic DCR, head and neck ultrasound, and trends in surgical technology... a new section on rhinology... and coverage of hot topics including Botox. Get fresh perspectives from a new editorial board and many new contributors. Find what you need faster through a streamlined format, reorganized chapters, and a color design that expedites reference.
This is the first major work to apply to the rule of law the insights of modern cultural theory, ranging from Clifford Geertz to Michel Foucault. Starting from Thomas Paine's observation that "in America, law is king," Paul Kahn asks: What are the elements of our belief in the rule of law? And what are the rhetorical techniques by which the courts maintain this belief? Kahn centers his exploration on the 1803 Supreme Court case of Marbury v. Madison - still the greatest of our constitutional cases. Kahn shows that Marbury is the judicial response to President Thomas Jefferson's belief that his election represented a Second American Revolution. Kahn uses the confrontation between president and Court to analyze the contrasting ways in which the revolutionary and the legal imaginations understand and give shape to political events. This contest continues today in the conflicting demands we make for a politics that preserves the past yet celebrates popular innovation.
Spotlights the threats of global warming and offers a systems approach for possible treatments. Decades spent as a physician and public health scientist have allowed Dr. Epstein to examine and now comment on the dynamics of global politics, climate change, and global health. Together with journalist Dan Ferber, he expresses a fundamental need for communities (of all scales) and industries (of all kinds) to reach together for a low-carbon economy. They make their argument by combining personal accounts with accurate histories and industry case studies. What enfolds is a prescriptive narrative for repairing an ailing planet"--Provided by publisher.
It is paramount for clinicians to understand the distinguishing signs and symptoms among many different local and systemic neuro-ophthalmic disorders in order to provide the most efficacious evaluations and treatments. Clinical Pathways in Neuro-Ophthalmology: An Evidence-Based Approach, Third Edition reflects the authors' extensive training and experience in the field of neuro-ophthalmology, as well as updates in the field. Stacy Smith, Andrew Lee, Paul Brazis, and an impressive group of contributors have written an unsurpassed learning tool on how to manage patients with known or presumed neuro-ophthalmologic conditions, in the most logical, straightforward, and cost-effective manner. The authors share significant clinical pearls and knowledge throughout 20 chapters. The book lays a solid foundation on the management of neurologic eye disorders including symptoms, ophthalmologic testing, diagnosis, and treatment. Among the discussed disorders are anterior and retrobulbar optic neuropathies, disorders of ocular motility and alignment, lid abnormalities, and anisocoria. Insights are provided on key topics including the use of office examinations, laboratory tests, and neuroimaging studies to make an ophthalmologic diagnosis; and ophthalmologic therapy to treat eye movement disorders such as nystagmus. Key Highlights Unique graphic algorithms help clinicians differentiate conditions with frequently overlapping clinical manifestations The evaluation and treatment of various neuro-ophthalmologic processes, stratified by four classes of evidence and four levels of clinical recommendation A basic set of references for each subject enables readers to expand knowledge High quality four-color clinical images enhance learning This book is essential reading for neuro-ophthalmologists, ophthalmologists, neurologists, and residents and fellows in these fields of medicine.
A fundamental critique of American law and legal thought, Against the Law consists of a series of essays written from three different perspectives that coalesce into a deep criticism of contemporary legal culture. Paul F. Campos, Pierre Schlag, and Steven D. Smith challenge the conventional representations of the legal system that are articulated and defended by American legal scholars. Unorthodox, irreverent, and provocative, Against the Law demonstrates that for many in the legal community, law has become a kind of substitute religion--an essentially idolatrous practice composed of systematic self-misrepresentation and self-deception. Linked by a persistent inquiry into the nature and identity of "the law," these essays are informed by the conviction that the conventional representations of law, both in law schools and the courts, cannot be taken at face value--that the law, as commonly conceived, makes no sense. The authors argue that the relentlessly normative prescriptions of American legal thinkers are frequently futile and, indeed, often pernicious. They also argue that the failure to recognize the role that authorship must play in the production of legal thought plagues both the teaching and the practice of American law. Ranging from the institutional to the psychological and metaphysical deficiencies of the American legal system, the depth of criticism offered by Against the Law is unprecedented. In a departure from the nearly universal legitimating and reformist tendencies of American legal thought, this book will be of interest not only to the legal academics under attack in the book, but also to sociologists, historians, and social theorists. More particularly, it will engage all the American lawyers who suspect that there is something very wrong with the nature and direction of their profession, law students who anticipate becoming part of that profession, and those readers concerned with the status of the American legal system.
During the past 5 years rapid progress has been made in the understanding of biochemical pathways for signal transduction in lymphocyte activation. Gene cloning technology has been instrumental in defining and making available in pure form of a number of growth and differentiation factors, in the characterization of their receptors, and in the delineation of genes for the T cell receptor. This book is divided into 6 sections. Section 1 deals with the molecular structure of the T cell receptor. Section 2 discusses the role of the T cell receptor, membrane ion channels and biochemical pathways of signal transduction in T cell activation. The molecular structures and biological and immunological effects of interleukin 1, interleukin 2 and interleukin 3 are presented in Section 3. This section also details the structure of interleukin 2 receptor and its use as a target for therapy for certain leukemias. Section 4 includes the biochemical events which occur following the delivery of the signal for B cell activation, proliferation, and differentiation by antigen, growth/differentiation factors. The molecular structure of B cell stimulating factors is also discussed. The role of oncogene expression in cellular activation and differentiation is included in Section 5. The cellular and molecular basis of natural killing and the molecular basis of cyc1osporin A-mediated immunosuppression are discussed in detail in Section 6. We hope this book will serve as a reference work on basic mechanisms of lymphocyte activation, proliferation, and differentiation for immunologists and molecular biologists.
The precise relationship between viral infection and malignancy remains an epidemiologic association and the subject of active investigation. Nonmalignant hematologic disorders have a similarly complex relationship with cancer-associated viruses and may offer insight into the pathogenesis of oncogenesis. This book explores the relationships between viral infections, immune impairments and the hematologic and malignant diseases, particularly against the backdrop of the HIV epidemic. By extending the scope to all of viral oncology the editors provide an invaluable resource on tumors related to other viruses other than HIV, particularly carcinomas of the cervix and anus with HPV and tumors of the liver with the various hepatitis viruses.
Family, Work, and Household presents the social and occupational life of a late medieval Iberian town in rich, unprecedented detail. The book combines a diachronic study of two regionally prominent families—one knightly and one mercantile—with a detailed cross-sectional urban study of household and occupation. The town in question is the market town and administrative centre of Manresa in Catalonia, whose exceptional archives make such a study possible. For the diachronic studies, Fynn-Paul relied upon the fact that Manresan archives preserve scores of individual family notarial registers, and the cross-sectional study was made possible by the Liber Manifesti of 1408, a cadastral survey which details the property holdings of individual householders to an unusually thorough degree. In these pages, the economic and social strategies of many individuals, including both knights and burghers, come to light over the course of several generations. The Black Death and its aftermath play a prominent role in changing the outlook of many social actors. Other chapters detail the socioeconomic topography of the town, and examine occupational hierarchies, for such groups as rentiers, merchants, leatherworkers, cloth workers, women householders, and the poor.
Written by an ophthalmologist and a neurologist with more than 30 years experience between them, this is the first book devoted specifically to differential diagnosis in neuro-ophthalmology. The expanded and updated second edition uses an evidence-based approach to link symptoms to specific findings, and covers all major advances in the field.The book utilizes a series of easy-to-follow pathways - supported by helpful tables and expertly written text - to help you walk through any clinical situation and confidently reach a diagnosis. Topics covered include: optic neuritis, diplopia, lid retraction, nerve palsies, and much more!Benefit from these key features:- Emphasis on cost-effective, evidence-based techniques- Coverage of new topics such as optic nerve glioma, meningiomas, and papilledema- Valuable tables of pathologies and clinical findings that help detect unusual signs and avoid common misinterpretations- Practical, easy-to-use format - written with the front line clinician in mind- Thousands of useful and updated referencesHere is an invaluable resource for all ophthalmologists, neurosurgeons, and neurologists who need the latest diagnostic and treatment techniques for neuro-ophthalmologic disorders. Residents and students will find it an outstanding introduction to the field.
In Lukewarming, two environmental scientists explain the science and spin behind the headlines and come to a provocative conclusion: climate change is real, and partially man-made, but it is becoming obvious that far more warming has been forecast than will occur, with some of the catastrophic impacts implausible or impossible. Global warming is more lukewarm than hot. This fresh analysis is an invaluable source for those looking to be more informed about global warming and the data behind it.
Organized developmentally with sections on infants and children, adolescents, adults and the elderly, this helpful reference covers all the clinical conditions that are seen, diagnosed and managed in the primary care setting.
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