Paul M. Stewart's Books

Amiable Scoundrel

Simon Cameron, Lincoln's Scandalous Secretary of War

By: Paul Kahan

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Amiable Scoundrel

Simon Cameron, Lincoln's Scandalous Secretary of War

By: Paul Kahan

From abject poverty to undisputed political boss of Pennsylvania, Lincoln's secretary of war, senator, chair of the Senate Foreign Relations Committee, and a founder of the Republican Party, Simon Cameron (1799-1889) was one of the nineteenth century's most prominent political figures. In his wake, however, he left a series of questionable political and business dealings and, at the age of eighty, even a sex scandal. Far more than a biography of Cameron, Amiable Scoundrel is also a portrait of an era that allowed--indeed, encouraged--a man such as Cameron to seize political control. The political changes of the early nineteenth century enabled him not only to improve his status but also to exert real political authority. The changes caused by the Civil War, in turn, allowed Cameron to consolidate his political authority into a successful, well-oiled political machine. A key figure in designing and implementing the Union's military strategy during the Civil War's crucial first year, Cameron played an essential role in pushing Abraham Lincoln to permit the enlistment of African Americans into the U.S. Army, a stance that eventually led to his forced resignation. Yet his legacy has languished, nearly forgotten save for the fact that his name has become shorthand for corruption, even though no evidence has ever been presented to prove that Cameron was corrupt. Amiable Scoundrel puts Cameron's actions into a larger historical context by demonstrating that many politicians of the time, including Abraham Lincoln, used similar tactics to win elections and advance their careers. This study is the fascinating story of Cameron's life and an illuminating portrait of his times.

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420

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U of Nebraska Press

Published Date

ISBN 10

1612348475

ISBN 13

9781612348476

Vascular Plants of Texas

A Comprehensive Checklist Including Synonymy, Bibliography, and Index

By: Stanley D. Jones,Joseph K. Wipff,Paul M. Montgomery

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Vascular Plants of Texas

A Comprehensive Checklist Including Synonymy, Bibliography, and Index

By: Stanley D. Jones,Joseph K. Wipff,Paul M. Montgomery

Everyone with a professional interest in the flora of Texas will welcome this checklist of the vascular plants. This comprehensive list also includes crops, persistent perennials, and naturalized plants and encompasses over 1,000 changes to the previous (Hatch, 1990) checklist. The authors have arranged this checklist phylogenetically by classes following the Cronquist system. Several features make this checklist especially useful. Chief among them is the relative synonymy (name history). An extensive index makes current classification and correct nomenclature readily accessible, while the botanical bibliography is the most extensive ever compiled for Texas. The authors also note which plants have been listed as threatened or endangered by the Texas Organization of Endangered Species, which are designated as Federal Noxious Weeds, and which have been chosen as state tree, flower, fruit, etc. by the Texas Legislature.

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417

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University of Texas Press

Published Date

ISBN 10

0292788541

ISBN 13

9780292788541

Heaven's Harsh Tableland

A New History of the Llano Estacado

By: Paul H. Carlson

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Heaven's Harsh Tableland

A New History of the Llano Estacado

By: Paul H. Carlson

The Llano Estacado—dubbed by author Paul H. Carlson as “heaven’s harsh tableland”—covers some 48,000 square miles of western Texas and eastern New Mexico. In this new survey of the region, the story begins during prehistoric times and with descendants of the Comanche, Apache, and other Native American tribal groups. Other groups have also left their marks on the area: Spanish explorers, Comancheros and other traders, European settlers, farmers and ranchers, artists, and even athletes. Carlson, a veteran historian, aims to review “the Llano’s historic contours from its earliest foundations to its energetic present,” and in doing so, he skillfully narrates the story of the region up to the present time of modern agribusiness and urbanization. Throughout the ten chronologically arranged chapters, concise sidebars support the narrative, highlighting important and interesting topics such as the enigmatic origins of the region’s name, fascinating geological and paleontological facts, the arrival of humans, the natural history of bison, colorful “characters” in the history of the region, and many others. The resulting broad synthesis captures the entirety of the Llano Estacado, summarizing and interpreting its natural and human history in a single, carefully researched and clearly written volume. Heaven’s Harsh Tableland: A New History of the Llano Estacado will provide a helpful, enjoyable, and authoritative guide to the history and development of this important region.

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537

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Texas A&M University Press

Published Date

ISBN 10

1648431550

ISBN 13

9781648431555

Neuropsychological Aspects of Substance Use Disorders

Evidence-Based Perspectives

By: Daniel N. Allen,Steven Paul Woods

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Neuropsychological Aspects of Substance Use Disorders

Evidence-Based Perspectives

By: Daniel N. Allen,Steven Paul Woods

In Neuropsychological Aspects of Substance Use Disorders, internationally recognized experts provide clinicians with the most up to date information on the neuropsychology of substance use disorders based on the empirical literature. Substance use disorders continue to be a major health concern in the United States and worldwide, although their causes and effective treatments remain elusive. Research in this area has expanded dramatically over the past two decades and provided insights into psychobiological, behavioral, and genetic factors that contribute to the onset and maintenance of substance use disorders and associated neuropsychological abnormalities. This research has provided a strong empirical foundation that has direct implications for clinical neuropsychological practice and created a need to provide the practitioner with a cogent and up-to-date summary of current developments, which is the goal of this volume. Chapters in this volume are organized into three sections that are designed to provide a translational overview of basic research and treatment findings regarding addictions, neuropsychological and neurological sequalae of the most common substances of abuse, and consideration of special issues that might confound interpretation of neuropsychological test results. Section I provides an overview of addictions, including diagnoses based on the DSM-IV, as well as the most current conceptualizations of addiction from psychobiological, genetic, and behavioral and no economics perspectives, providing the reader with a broad evidence-based conceptual framework. Section II reviews the most common substances of abuse including coverage of structural and functional neuroimaging findings, epidemiological evidence, and neuropsychological sequelae. Substances included in this section represent the most commonly encountered drugs of abuse. Section III includes coverage of the number of special topics, including specific issues related to psychiatric, medical, and neurological comorbidities. Topics included in this section represent areas of common concerns faced by clinical neuropsychologists in the interpretation and application of neuropsychological test results.

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475

Publisher

Oxford University Press

Published Date

ISBN 10

0190845767

ISBN 13

9780190845766

Clinical Psychology, Research and Practice: an Introductory Text, 4e

By: Paul Bennett

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Clinical Psychology, Research and Practice: an Introductory Text, 4e

By: Paul Bennett

“This book provides an excellent introduction to clinical psychology. Written in an accessible style, the text effectively combines theory and research with practice examples and case studies.” —Jason Davies, Professor of Forensic and Clinical Psychology, Swansea University “Comprehensive on key areas, theories and models.” —Jessica Fielding, Lecturer in Psychology, University of Bristol “Case formulations bring to life the various disorders presented here. A scholarly discussion of developments in clinical practice including third wave cognitive behavioural therapies is another unique strength. I highly recommend this as a key text for practitioner psychology trainees and health care professionals working in medical settings.” —Christina Liossi, Chair in Paediatric Psychology, University of Southampton and Honorary Consultant in Paediatric Psychology, Great Ormond Street Hospital for Children NHS Foundation Trust Extensively updated, this popular and accessibly written textbook outlines the latest research and therapeutic approaches within clinical psychology, alongside important developments in clinical practice. The book introduces and evaluates the conceptual models of mental health problems and their treatment, including second and third wave therapies. Each disorder is considered from a psychological, social and biological perspective and different intervention types are thoroughly investigated. Key updates to this edition include: •The development of case formulations for conditions within each chapter •An articulation and use of modern theories of psychopathology, including sections on the transdiagnostic approach, meta-cognitive therapy, and acceptance and commitment therapy •An introduction to emerging mental health issues, such as internet gaming disorder •Challenging ‘stop and think’ boxes that encourage readers to address topical issues raised in each chapter, such as societal responses to topics as varied as psychopathy, paedophilia and the Black Lives Matter movement •New vocabulary collated into key terms boxes for easy reference Paul Bennett is Professor of Clinical and Health Psychology at the University of Swansea. He has previously worked as a clinical psychologist, as well as an academic at Cardiff and Bristol universities. He has published over 125 academic papers, in addition to a number of highly regarded student-focused books Praise for the previous edition: "This book provided an invaluable orientation to the grounding theoretical principles of clinical health psychology, how this knowledge can be applied by psychologists in healthcare settings, particular assessment and intervention approaches and issues associated with working with patients in healthcare settings ... I would highly recommend this as a key text for clinical psychology trainees and postgraduates working or researching in medical settings across the lifespan, both as a general orientation tool and a resource to refer to with reference to specific presenting issues. Fleur-Michelle Coiffait, Doctoral student, University of Edinburgh, UK "The tone of this volume is well pitched; it is written in clear English yet without being over-simplified. New vocabulary is collated into ‘key terms’ boxes for easy reference at the end of the chapter – a useful device for the new student. Also proffered at chapter end are ‘For Discussion’ boxes, encouraging the reader to critically assess and compare the contents of the chapter, along with useful suggestions for further reading. With a good level of detail without swamping the reader, this volume is an excellent introduction to students of abnormal psychology." Hayley Burgess, Psychology Graduate

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570

Publisher

McGraw-Hill Education (UK)

Published Date

ISBN 10

0335249000

ISBN 13

9780335249008

Links Golf

The Inside Story

By: Paul Daley

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Links Golf

The Inside Story

By: Paul Daley

“Encompassing the history, tradition, and images of the great links, this book is a worthy travelling companion, and guide, on your golfing journey.” —Ian Baker-Finch, Australian professional golfer and sports commentator On the short list for the 2000 USGA International Book Award for “outstanding golf book of the year,” Links Golf: The Inside Story describes the beautiful land on which the links courses are built. Daley explains the term “links” and discusses their architecture, style, and great clusters. This behind-the-scenes look at the health of links golf in Britain puts an emphasis on elements that are undermining its viability and long-term future. In a time when many treeless courses are claiming to be genuine, Daley explains how to determine what is and what is not a links course. Concentrating on Great Britain and Ireland, he also examines the unique characteristics of this early form of seaside golf, how geological processes helped shaped the land, and how links golf differs from inland golf. “Links are the soul of the game—the greatest places on which to play, and they teach us much about the way the game ought to be. So does this book.” —Michael Clayton, Australian professional golfer, golf course architect, and sports commentator

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212

Publisher

Pelican Publishing

Published Date

ISBN 10

1455607401

ISBN 13

9781455607402

Political Participation in Britain

The Decline and Revival of Civic Culture

By: Paul Whiteley

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Political Participation in Britain

The Decline and Revival of Civic Culture

By: Paul Whiteley

This broad-ranging text examines the big issues about political attitudes, behaviour and participation in contemporary Britain. Written by a leading expert and drawing on extensive research, this will be essential reading for all students of British politics and everyone involved in the world of politics and policy.

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216

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Bloomsbury Publishing

Published Date

ISBN 10

0230358497

ISBN 13

9780230358492

A Most Wicked Conspiracy

The Last Great Swindle of the Gilded Age

By: Paul Starobin

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A Most Wicked Conspiracy

The Last Great Swindle of the Gilded Age

By: Paul Starobin

A tale of Gilded Age corruption and greed from the frontier of Alaska to America's capital. In the feverish, money-making age of railroad barons, political machines, and gold rushes, corruption was the rule, not the exception. Yet the Republican mogul "Big Alex" McKenzie defied even the era's standard for avarice. Charismatic and shameless, he arrived in the new Alaskan territory intent on controlling gold mines and draining them of their ore. Miners who had rushed to the frozen tundra to strike gold were appalled at his unabashed deviousness. A Most Wicked Conspiracy recounts McKenzie's plot to rob the gold fields. It's a story of how America's political and economic life was in the grip of domineering, self-dealing, seemingly-untouchable party bosses in cahoots with robber barons, Senators and even Presidents. Yet it is also the tale of a righteous resistance of working-class miners, muckraking journalists, and courageous judges who fought to expose a conspiracy and reassert the rule of law. Through a bold set of characters and a captivating narrative, Paul Starobin examines power and rampant corruption during a pivotal time in America, drawing undoubted parallels with present-day politics and society.

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283

Publisher

PublicAffairs

Published Date

ISBN 10

154174229X

ISBN 13

9781541742291

Against All Odds

History of Saint Andrew's Parish Church, Charleston, 1706-2013

By: Paul Porwoll

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Against All Odds

History of Saint Andrew's Parish Church, Charleston, 1706-2013

By: Paul Porwoll

The tranquility of the magnificently restored Saint Andrews Parish Church, surrounded by stately oaks and ancient gravestones, belies a tumultuous past. If its walls could talk, they would tell a story as old as the human condition. Founded in the forest of a new colony, this simple Anglican church served planters and their slaves during the heyday of rice and indigo. Before the Civil War, ministry shifted to the slaves, and afterward to freed men and women. Following years of decline and neglect, Saint Andrews rose like the phoenix. The history of the oldest surviving church south of Virginia and the only remaining colonial cruciform church in South Carolina is one of wealth and poverty, acclaim and anonymity, slavery and freedom, war and peace, quarrelling and cooperation, failure and achievement. It is the story of a church that has refused to die, against all odds.

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472

Publisher

WestBow Press

Published Date

ISBN 10

1490818170

ISBN 13

9781490818177

Talking about Good and Bad Without Getting Ugly

A Guide to Moral Persuasion

By: Paul Chamberlain

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Talking about Good and Bad Without Getting Ugly

A Guide to Moral Persuasion

By: Paul Chamberlain

ABORTION. GAY MARRIAGE. EUTHANASIA. How do we talk about these issues in a pluralistic society? The truth is that we often avoid such conversations in order not to offend others or appear intolerant. But in doing so, we miss out on opportunities to influence others' views and make a real difference in the world. In Talking About Good and Bad...

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206

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ReadHowYouWant.com

Published Date

ISBN 10

145874907X

ISBN 13

9781458749079

Clinical Anesthesia, 8e: eBook without Multimedia

By: Paul G. Barash

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Clinical Anesthesia, 8e: eBook without Multimedia

By: Paul G. Barash

Where experts turn for definitive answers! Clinical Anesthesia covers the full spectrum of clinical issues and options in anesthesiology, providing insightful coverage of pharmacology, physiology, co-existing diseases, and surgical procedures. Unmatched in its clarity and depth of coverage as well as its robust multimedia features, this classic clinical reference brings you the very latest essential knowledge in the field, equipping you to effectively apply today’s standards of care and make optimal clinical decisions on behalf of your patients.

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5197

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496337018

ISBN 13

9781496337016

Surface Water Quality

Have the Laws Been Successful?

By: Ruth Patrick,Faith Douglass,Drew M. Palavage,Paul M. Stewart

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Surface Water Quality

Have the Laws Been Successful?

By: Ruth Patrick,Faith Douglass,Drew M. Palavage,Paul M. Stewart

Addressing ecologists, legislators, lawyers, and industrialists alike, Ruth Patrick asks what has been accomplished with the millions of dollars spent on upgrading our surface waters. Has the water improved in spite of the fact that the crayfish, snails, and algae are not those that one would expect to find in natural rivers and estuaries? To evaluate the success of environmental laws over the past two decades, the author examines the aquatic life of river systems in the Delaware Valley, Texas, and Georgia--the only areas in the United States where she found enough biological data to determine trends over time. Although tracing the impact of environmental laws is difficult, Patrick found that for these three water systems the results were generally positive. However, if society as a whole wants effective environmental legislation, organizations must take on a more systematic and orderly approach to data gathering. Patrick argues that in monitoring the waters, one must study protozoa, algae, and worms as well as fish, oysters, and shrimp; one must track amounts of metal as well as low concentrations of oxygen. In proposing options for the future, the author predicts that the cost of such monitoring will be higher than present expenditures, but the cost of lax control will be even greater. Originally published in 1992. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.

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217

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Princeton University Press

Published Date

ISBN 10

1400862779

ISBN 13

9781400862771

The Knowledge Polity

Teaching and Research in the Social Sciences

By: Paul A. Djupe,Amy Erica Smith,Anand Edward Sokhey

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The Knowledge Polity

Teaching and Research in the Social Sciences

By: Paul A. Djupe,Amy Erica Smith,Anand Edward Sokhey

This chapter introduces our holistic view of knowledge production in sociology and political science. Enlarging our view beyond the individualistic publication pipeline metaphor, we press the conception of academics as citizens of a knowledge polity with rights and responsibilities. Knowledge production does not just mean research, but encompasses teaching, reviewing, blogging, commenting, and other activities, which signal its communal nature. We then advance an explanation for knowledge production that situates academics in institutional and social contexts - including the family - while maintaining individual agency. We search for inequalities by gender and racial/ethnic identification, but are careful to consider the changing compositions of political science and sociology (both are diversifying steadily) and different situations (e.g., faculty rank) when making comparisons. The chapter describes our PASS study, which sampled academic departments and surveyed 1,700 faculty in 2017. Respondent reports were linked with data on lifetime publications, Twitter activity and other data"--

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321

Publisher

Oxford University Press

Published Date

ISBN 10

0197611915

ISBN 13

9780197611913

The Idea of Poverty

By: Paul Spicker

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The Idea of Poverty

By: Paul Spicker

Paul Spicker examines views about what poverty is and what should be done about it. 'Poverty' means many different things to different people - for example, lack of money or dependency on benefits. Here, he makes an argument for a participative, inclusive understanding of the term.

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184

Publisher

Policy Press

Published Date

ISBN 10

1861348886

ISBN 13

9781861348883

Localization in Clinical Neurology

By: Paul Brazis,Joseph C. Masdeu,José Biller

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Localization in Clinical Neurology

By: Paul Brazis,Joseph C. Masdeu,José Biller

Develop and perfect your neurological localization skills with the gold standard text in the field. Anatomical localization skills based in physical examination are essential for any clinician caring for patients with neurologic disease processes. Newly revised and updated, Localization in Clinical Neurology, Seventh Edition, uses detailed, easy-to-read descriptions and full-color illustrations to help you understand and pinpoint the source of a patient’s signs and symptoms. Improve your diagnostic accuracy and avoid unnecessary testing with this outstanding roadmap to neurologic diagnosis.

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1220

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1496356152

ISBN 13

9781496356154

Stochastic Processes in Cell Biology

By: Paul C. Bressloff

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Stochastic Processes in Cell Biology

By: Paul C. Bressloff

This book develops the theory of continuous and discrete stochastic processes within the context of cell biology. A wide range of biological topics are covered including normal and anomalous diffusion in complex cellular environments, stochastic ion channels and excitable systems, stochastic calcium signaling, molecular motors, intracellular transport, signal transduction, bacterial chemotaxis, robustness in gene networks, genetic switches and oscillators, cell polarization, polymerization, cellular length control, and branching processes. The book also provides a pedagogical introduction to the theory of stochastic process – Fokker Planck equations, stochastic differential equations, master equations and jump Markov processes, diffusion approximations and the system size expansion, first passage time problems, stochastic hybrid systems, reaction-diffusion equations, exclusion processes, WKB methods, martingales and branching processes, stochastic calculus, and numerical methods. This text is primarily aimed at graduate students and researchers working in mathematical biology and applied mathematicians interested in stochastic modeling. Applied probabilists and theoretical physicists should also find it of interest. It assumes no prior background in statistical physics and introduces concepts in stochastic processes via motivating biological applications. The book is highly illustrated and contains a large number of examples and exercises that further develop the models and ideas in the body of the text. It is based on a course that the author has taught at the University of Utah for many years.

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688

Publisher

Springer

Published Date

ISBN 10

3319084887

ISBN 13

9783319084886

Localization in Clinical Neurology

By: Paul W. Brazis,Joseph C. Masdeu,Jose Biller

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Localization in Clinical Neurology

By: Paul W. Brazis,Joseph C. Masdeu,Jose Biller

Anatomical localization skills based in physical examination are essential for any clinician caring for patients with neurologic disease processes. Now fully revised and up to date, Localization in Clinical Neurology, 8th Edition, uses easy-to-read descriptions, full-color illustrations and videos to help readers understand and locate the source of a patient’s signs and symptoms. This gold standard text now features dozens of clinical videos that help clinicians improve diagnostic accuracy and avoid unnecessary testing.

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1287

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1975160266

ISBN 13

9781975160265

Volcanoes of the World

Third Edition

By: Lee Siebert,Tom Simkin,Paul Kimberly

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Volcanoes of the World

Third Edition

By: Lee Siebert,Tom Simkin,Paul Kimberly

This impressive scientific resource presents up-to-date information on ten thousand years of volcanic activity on Earth. In the decade and a half since the previous edition was published new studies have refined assessments of the ages of many volcanoes, and several thousand new eruptions have been documented. This edition updates the book’s key components: a directory of volcanoes active during the Holocene; a chronology of eruptions over the past ten thousand years; a gazetteer of volcano names, synonyms, and subsidiary features; an extensive list of references; and an introduction placing these data in context. This edition also includes new photographs, data on the most common rock types forming each volcano, information on population densities near volcanoes, and other features, making it the most comprehensive source available on Earth’s dynamic volcanism.

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564

Publisher

Univ of California Press

Published Date

ISBN 10

0520947932

ISBN 13

9780520947931

The Papers of Andrew Johnson

By: Andrew Johnson,Paul H. Bergeron

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The Papers of Andrew Johnson

By: Andrew Johnson,Paul H. Bergeron

The correspondence in this volume is related to Johnson's presidency during the Reconstruction Era, including the president's impeachment and the subsequent trial, which resulted in the Senate narrowly voting not to remove him from office.

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782

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Univ. of Tennessee Press

Published Date

ISBN 10

0870499467

ISBN 13

9780870499463

Services Marketing

By: Christopher Lovelock,Paul Patterson

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Services Marketing

By: Christopher Lovelock,Paul Patterson

Services Marketing is well known for its authoritative presentation and strong instructor support. The new 6th edition continues to deliver on this promise. Contemporary Services Marketing concepts and techniques are presented in an Australian and Asia-Pacific context. In this edition, the very latest ideas in the subject are brought to life with new and updated case studies covering the competitive world of services marketing. New design features and a greater focus on Learning Objectives in each chapter make this an even better guide to Services Marketing for students. The strategic marketing framework gives instructors maximum flexibility in teaching. Suits undergraduate and graduate-level courses in Services Marketing.

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529

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Pearson Australia

Published Date

ISBN 10

1486004768

ISBN 13

9781486004768

Paul Henry

With a Catalogue of the Paintings, Drawings, Illustrations

By: S. B. Kennedy,Paul Henry

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Paul Henry

With a Catalogue of the Paintings, Drawings, Illustrations

By: S. B. Kennedy,Paul Henry

This is a biography of Paul Henry's life and artistic achievements, especially his idyllic landscape paintings of the west of Ireland. It interweaves the life of his talented wife, Grace, and explores his friendships and associations with Paris and Dublin.

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363

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Yale University Press

Published Date

ISBN 10

0300117124

ISBN 13

9780300117127

Partnership and the High Performance Workplace

Work and Employment Relations in the Aerospace Industry

By: Andy Danford,Mike Richardson,Paul Stewart,Stephanie Tailby,Martin Upchurch

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Partnership and the High Performance Workplace

Work and Employment Relations in the Aerospace Industry

By: Andy Danford,Mike Richardson,Paul Stewart,Stephanie Tailby,Martin Upchurch

The promotion of workplace partnership in the high performance workplace has become central to policy debates on the 'modernization' of employment relations in British industry. This book provides critical insights into the dynamics of partnership by way of in-depth case studies of employee experience in an under-researched industry noted for its high concentrations of skilled workers and graduates. Drawing on rich interview and questionnaire data, the authors highlight considerable conflicts of interest in the development of partnership that derive from the competitive capitalist environment in which management strategies operate.

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277

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Springer

Published Date

ISBN 10

0230501990

ISBN 13

9780230501997

Mechanisms of DNA Repair

By: Paul Doetsch

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Mechanisms of DNA Repair

By: Paul Doetsch

Mechanisms of DNA Repair.

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354

Publisher

Academic Press

Published Date

ISBN 10

0123876656

ISBN 13

9780123876652

An Integrated Guide to Human Drug Metabolism

From Basic Chemical Transformations to Drug-Drug Interactions

By: Mark Ashton,Paul W. Groundwater,Sophie Stocker,Adam Todd

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An Integrated Guide to Human Drug Metabolism

From Basic Chemical Transformations to Drug-Drug Interactions

By: Mark Ashton,Paul W. Groundwater,Sophie Stocker,Adam Todd

An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines and other drugs. Each of the human metabolic processes will be covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, An Integrated Guide to Human Drug Metabolism is useful for students and researchers needing a reference for interdisciplinary research in drug interactions. Metabolism is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects. - Covers each of the human metabolic processes, employing examples drawn from known metabolic transformations of drugs used clinically - Provides an integrated approach, linking together the science and practice strands of human drug metabolism - Contains questions and answers to assess learning of material and real-life case studies

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278

Publisher

Elsevier

Published Date

ISBN 10

0323993753

ISBN 13

9780323993753

Book's by Paul M. Stewart

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